HK1193407A1 - Pyrrolidine-3-ylacetic acid derivative -3- - Google Patents

Pyrrolidine-3-ylacetic acid derivative -3-

Info

Publication number
HK1193407A1
HK1193407A1 HK14106800.1A HK14106800A HK1193407A1 HK 1193407 A1 HK1193407 A1 HK 1193407A1 HK 14106800 A HK14106800 A HK 14106800A HK 1193407 A1 HK1193407 A1 HK 1193407A1
Authority
HK
Hong Kong
Prior art keywords
pyrrolidine
acid derivative
ylacetic acid
ylacetic
derivative
Prior art date
Application number
HK14106800.1A
Other languages
English (en)
Chinese (zh)
Inventor
吉田郎
岡部忠志
松本泰信
渡邊信久
大橋芳章
鬼澤裕二
原田均
Original Assignee
衛材 管理有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 衛材 管理有限公司 filed Critical 衛材 管理有限公司
Publication of HK1193407A1 publication Critical patent/HK1193407A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
HK14106800.1A 2011-09-13 2014-07-04 Pyrrolidine-3-ylacetic acid derivative -3- HK1193407A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011199482 2011-09-13
PCT/JP2012/073171 WO2013039057A1 (fr) 2011-09-13 2012-09-11 Dérivé de l'acide pyrrolidin-3-ylacétique

Publications (1)

Publication Number Publication Date
HK1193407A1 true HK1193407A1 (en) 2014-09-19

Family

ID=47883287

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14106800.1A HK1193407A1 (en) 2011-09-13 2014-07-04 Pyrrolidine-3-ylacetic acid derivative -3-

Country Status (32)

Country Link
EP (1) EP2757103B1 (fr)
JP (1) JP5829689B2 (fr)
KR (1) KR101963922B1 (fr)
CN (1) CN103764648B (fr)
AR (1) AR087788A1 (fr)
AU (1) AU2012309556B2 (fr)
BR (1) BR112014004267B1 (fr)
CA (1) CA2844617C (fr)
CL (1) CL2014000484A1 (fr)
CY (1) CY1117460T1 (fr)
DK (1) DK2757103T3 (fr)
ES (1) ES2564732T3 (fr)
HK (1) HK1193407A1 (fr)
HR (1) HRP20160166T1 (fr)
HU (1) HUE026824T2 (fr)
IL (1) IL230804A (fr)
JO (1) JO3082B1 (fr)
ME (1) ME02383B (fr)
MX (1) MX358494B (fr)
MY (1) MY169869A (fr)
PE (1) PE20141353A1 (fr)
PL (1) PL2757103T3 (fr)
PT (1) PT2757103E (fr)
RS (1) RS54582B1 (fr)
RU (1) RU2615135C2 (fr)
SG (1) SG11201400163WA (fr)
SI (1) SI2757103T1 (fr)
SM (1) SMT201600071B (fr)
TW (1) TWI543975B (fr)
UA (1) UA112873C2 (fr)
WO (1) WO2013039057A1 (fr)
ZA (1) ZA201400918B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2900926A1 (fr) * 2013-03-12 2014-09-18 Eisai R&D Management Co., Ltd. Sel de derive d'acide pyrrolidin-3-yl acetique et cristaux correspondants
WO2014142086A1 (fr) * 2013-03-13 2014-09-18 エーザイ・アール・アンド・ディー・マネジメント株式会社 Dérivé acétate de pyrrolidin-3-yle et dérivé d'acétate de piperidin-3-yle
US20240199558A1 (en) 2022-10-19 2024-06-20 Astrazeneca Ab 2,4,6-trisubstituted 1,3,5-triazines as modulators of cx3cr1

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4263391B2 (ja) 2001-03-19 2009-05-13 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗cx3cr1抗体、抗フラクタルカイン抗体及びフラクタルカインの利用
AU2002363236A1 (en) * 2001-10-30 2003-05-12 Millennium Pharmaceuticals, Inc. Compounds, pharmaceutical compositions and methods of use therefor
US20070142386A1 (en) * 2003-10-07 2007-06-21 Astrazeneca New 2-substituted, 4-amino-thiazolo[4,5-d] pyrimidines, useful as chemokine receptor antagonists, esp. cx3cr1
AR053347A1 (es) * 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
UA90707C2 (en) 2005-04-06 2010-05-25 Астразенека Аб Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives
CA2664930A1 (fr) 2006-09-29 2008-04-03 Astrazeneca Ab Nouveaux derives de [1, 3 ]thiazolo[4, 5-d]pyrimidine-2(3h)-amine 5,7-disubstitutes et leur utilisation en therapie
TW200820973A (en) 2006-09-29 2008-05-16 Astrazeneca Ab Novel compounds 480
AR063275A1 (es) * 2006-10-12 2009-01-14 Epix Delaware Inc Compuestos de carboxamida, una composicion farmaceutica que los comprende y su uso en la preparacion de un medicamento para el tratamiento de enfermedades mediadas por la activacion de ccr2.
DK2262777T3 (en) * 2008-03-07 2016-05-17 Acraf 1-benzyl-3-hydroxymetylindazolderivater and their use in the treatment of diseases based on the expression of MCP-1 and CX3CR1
AR071036A1 (es) 2008-03-26 2010-05-19 Astrazeneca Ab Derivados 5, 7-disustituidos de [1, 3]tiazolo[4, 5-d]pirimidin-2 (3h)-ona, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades mediadas por el receptor cx3cr1.

Also Published As

Publication number Publication date
PE20141353A1 (es) 2014-09-26
CN103764648B (zh) 2015-07-01
ME02383B (fr) 2016-06-20
CL2014000484A1 (es) 2014-08-22
SMT201600071B (it) 2016-04-29
SI2757103T1 (sl) 2016-04-29
CA2844617C (fr) 2019-03-05
CY1117460T1 (el) 2017-04-26
EP2757103B1 (fr) 2016-01-06
JPWO2013039057A1 (ja) 2015-03-26
AU2012309556B2 (en) 2016-09-15
AR087788A1 (es) 2014-04-16
CN103764648A (zh) 2014-04-30
ZA201400918B (en) 2015-07-29
IL230804A0 (en) 2014-03-31
BR112014004267B1 (pt) 2021-11-16
RU2014107536A (ru) 2015-10-20
DK2757103T3 (en) 2016-03-07
HRP20160166T1 (hr) 2016-03-11
IL230804A (en) 2016-02-29
MX358494B (es) 2018-08-23
KR101963922B1 (ko) 2019-03-29
WO2013039057A1 (fr) 2013-03-21
ES2564732T3 (es) 2016-03-28
PL2757103T3 (pl) 2016-06-30
BR112014004267A2 (pt) 2017-03-21
MX2014002210A (es) 2014-04-30
UA112873C2 (uk) 2016-11-10
AU2012309556A1 (en) 2014-02-27
JP5829689B2 (ja) 2015-12-09
PT2757103E (pt) 2016-03-31
TW201311667A (zh) 2013-03-16
EP2757103A1 (fr) 2014-07-23
MY169869A (en) 2019-05-27
CA2844617A1 (fr) 2013-03-21
NZ620469A (en) 2015-06-26
SG11201400163WA (en) 2014-06-27
HUE026824T2 (en) 2016-07-28
TWI543975B (zh) 2016-08-01
KR20140060286A (ko) 2014-05-19
EP2757103A4 (fr) 2015-02-18
RU2615135C2 (ru) 2017-04-04
JO3082B1 (ar) 2017-03-15
RS54582B1 (en) 2016-08-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230909