HK1191984A1 - 用於酶在體傳感器的改進的擴散層 - Google Patents

用於酶在體傳感器的改進的擴散層

Info

Publication number
HK1191984A1
HK1191984A1 HK14105358.9A HK14105358A HK1191984A1 HK 1191984 A1 HK1191984 A1 HK 1191984A1 HK 14105358 A HK14105358 A HK 14105358A HK 1191984 A1 HK1191984 A1 HK 1191984A1
Authority
HK
Hong Kong
Prior art keywords
enzymatic
diffusion layer
vivo sensor
improved diffusion
vivo
Prior art date
Application number
HK14105358.9A
Other languages
English (en)
Inventor
Arnulf Staib
Marcel Thiele
Karl-Heinz Koelker
Ewald Rieger
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44511772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1191984(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1191984A1 publication Critical patent/HK1191984A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/002—Electrode membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q3/00—Condition responsive control processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
HK14105358.9A 2011-03-28 2014-06-09 用於酶在體傳感器的改進的擴散層 HK1191984A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11160007 2011-03-28
PCT/EP2012/055406 WO2012130841A1 (en) 2011-03-28 2012-03-27 Improved diffusion layer for an enzymatic in-vivo sensor

Publications (1)

Publication Number Publication Date
HK1191984A1 true HK1191984A1 (zh) 2014-08-08

Family

ID=44511772

Family Applications (2)

Application Number Title Priority Date Filing Date
HK14105358.9A HK1191984A1 (zh) 2011-03-28 2014-06-09 用於酶在體傳感器的改進的擴散層
HK15107281.6A HK1206793A1 (zh) 2011-03-28 2015-07-30 用於酶體內傳感器的改進的隔離膜

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK15107281.6A HK1206793A1 (zh) 2011-03-28 2015-07-30 用於酶體內傳感器的改進的隔離膜

Country Status (14)

Country Link
US (3) US10422765B2 (zh)
EP (1) EP2697388B1 (zh)
KR (1) KR20130122696A (zh)
CN (1) CN103443286B (zh)
AU (1) AU2012234345A1 (zh)
BR (1) BR112014021373B1 (zh)
DK (2) DK2697388T3 (zh)
ES (2) ES2637811T3 (zh)
HK (2) HK1191984A1 (zh)
IL (1) IL234190B (zh)
MX (1) MX2013011041A (zh)
PL (1) PL2697388T3 (zh)
SI (1) SI2697388T1 (zh)
WO (1) WO2012130841A1 (zh)

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EP3363910B1 (en) 2017-02-17 2023-12-06 Roche Diabetes Care GmbH Continuous analyte monitoring electrode with crosslinked enzyme
CN112074232A (zh) * 2018-05-04 2020-12-11 豪夫迈·罗氏有限公司 用于酶体内传感器的改进的扩散层
AU2019346733A1 (en) * 2018-09-27 2021-04-08 I-Sens, Inc. Polymer blend for controlling blood glucose influx, and continuous glucose monitoring biosensor comprising same
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EP4000517A1 (en) 2020-11-23 2022-05-25 Roche Diabetes Care GmbH Working electrode for an analyte sensor
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KR20230109639A (ko) 2020-11-24 2023-07-20 에프. 호프만-라 로슈 아게 상대/기준 전극을 제조하는 방법
EP4130729A1 (en) * 2021-08-04 2023-02-08 Roche Diabetes Care GmbH Opening formation in a membrane of a biosensor
EP4115806A1 (en) 2021-07-06 2023-01-11 Roche Diabetes Care GmbH Analyte sensor and method for manufacturing an analyte sensor
KR20240016431A (ko) 2021-07-06 2024-02-06 에프. 호프만-라 로슈 아게 분석물 센서 및 분석물 센서를 제조하는 방법
EP4140408A1 (en) 2021-08-30 2023-03-01 Roche Diabetes Care GmbH Membrane with biodegradable polymer
EP4151151A1 (en) 2021-09-21 2023-03-22 F. Hoffmann-La Roche AG Sensor with varying stiffness
EP4212095A1 (en) 2022-01-18 2023-07-19 F. Hoffmann-La Roche AG Analyte sensor and method for manufacturing an analyte sensor
WO2023122420A1 (en) 2021-12-24 2023-06-29 Roche Diabetes Care, Inc. Analyte sensor and method for manufacturing an analyte sensor
KR102389269B1 (ko) * 2022-02-16 2022-04-21 네메시스 주식회사 연속혈당측정 바이오센서용 글루코즈 확산 제어막 용액, 이를 포함하는 연속혈당측정 바이오센서용 글루코즈 확산 제어막 및 이를 포함하는 연속혈당측정용 바이오센서

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Also Published As

Publication number Publication date
HK1206793A1 (zh) 2016-01-15
CN103443286B (zh) 2015-09-23
AU2012234345A1 (en) 2013-09-05
SI2697388T1 (sl) 2015-07-31
DK2831263T3 (en) 2017-09-25
IL234190B (en) 2019-09-26
US20150005605A1 (en) 2015-01-01
BR112014021373B1 (pt) 2021-08-10
US20230258595A1 (en) 2023-08-17
EP2697388A1 (en) 2014-02-19
WO2012130841A1 (en) 2012-10-04
ES2637811T3 (es) 2017-10-17
KR20130122696A (ko) 2013-11-07
US10422765B2 (en) 2019-09-24
MX2013011041A (es) 2013-12-06
ES2707347T3 (es) 2019-04-03
PL2697388T3 (pl) 2015-11-30
BR112014021373A2 (pt) 2017-06-20
DK2697388T3 (en) 2015-08-31
US20140018653A1 (en) 2014-01-16
CN103443286A (zh) 2013-12-11
EP2697388B1 (en) 2015-05-20

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