BR112014021373A2 - sistema de eletrodo, sensor e uso de um copolímero hidrofílico. - Google Patents

sistema de eletrodo, sensor e uso de um copolímero hidrofílico.

Info

Publication number
BR112014021373A2
BR112014021373A2 BR112014021373A BR112014021373A BR112014021373A2 BR 112014021373 A2 BR112014021373 A2 BR 112014021373A2 BR 112014021373 A BR112014021373 A BR 112014021373A BR 112014021373 A BR112014021373 A BR 112014021373A BR 112014021373 A2 BR112014021373 A2 BR 112014021373A2
Authority
BR
Brazil
Prior art keywords
sensor
electrode system
hydrophilic copolymer
hydrophilic
copolymer
Prior art date
Application number
BR112014021373A
Other languages
English (en)
Other versions
BR112014021373B1 (pt
Inventor
Arnulf Staib
Ewald Rieger
Karl-Heinz Koelker
Marcel Thiele
Alexander Licht
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44511772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014021373(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority claimed from PCT/EP2013/056619 external-priority patent/WO2013144255A1/en
Publication of BR112014021373A2 publication Critical patent/BR112014021373A2/pt
Publication of BR112014021373B1 publication Critical patent/BR112014021373B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/002Electrode membranes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/005Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006Enzyme electrodes involving specific analytes or enzymes for glucose
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q3/00Condition responsive control processes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
BR112014021373-9A 2011-03-28 2013-03-27 Sistema de eletrodo, sensor e uso de um copolímero hidrofílico BR112014021373B1 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP11160007 2011-03-28
PCT/EP2012/055406 WO2012130841A1 (en) 2011-03-28 2012-03-27 Improved diffusion layer for an enzymatic in-vivo sensor
EPPCT/EP2012/055406 2012-03-27
PCT/EP2013/056619 WO2013144255A1 (en) 2012-03-27 2013-03-27 Improved spacer membrane for an enzymatic in-vivo sensor

Publications (2)

Publication Number Publication Date
BR112014021373A2 true BR112014021373A2 (pt) 2017-06-20
BR112014021373B1 BR112014021373B1 (pt) 2021-08-10

Family

ID=44511772

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014021373-9A BR112014021373B1 (pt) 2011-03-28 2013-03-27 Sistema de eletrodo, sensor e uso de um copolímero hidrofílico

Country Status (14)

Country Link
US (3) US10422765B2 (pt)
EP (1) EP2697388B1 (pt)
KR (1) KR20130122696A (pt)
CN (1) CN103443286B (pt)
AU (1) AU2012234345A1 (pt)
BR (1) BR112014021373B1 (pt)
DK (2) DK2697388T3 (pt)
ES (2) ES2707347T3 (pt)
HK (2) HK1191984A1 (pt)
IL (1) IL234190B (pt)
MX (1) MX2013011041A (pt)
PL (1) PL2697388T3 (pt)
SI (1) SI2697388T1 (pt)
WO (1) WO2012130841A1 (pt)

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ES2922701T3 (es) 2013-03-06 2022-09-19 Hoffmann La Roche Procedimiento para detectar un analito usando un sensor con catalizador de Mn2O3
JP7184643B2 (ja) * 2015-12-30 2022-12-06 デックスコム・インコーポレーテッド グルコース濃度の測定のためのデバイス
EP3263712A1 (en) * 2016-06-29 2018-01-03 Roche Diabetes Care GmbH Galvanically functionalized sensors
EP3551760A1 (en) 2016-12-08 2019-10-16 Roche Diabetes Care GmbH Sensor device for determining the concentration of an analyte underin-vivo
ES2969074T3 (es) 2017-02-17 2024-05-16 Hoffmann La Roche Electrodo de monitorización continua de analito con enzima reticulada
ES2924910T3 (es) * 2018-05-04 2022-10-11 Hoffmann La Roche Capa de difusión mejorada para un sensor enzimático in vivo
US20210355312A1 (en) * 2018-09-27 2021-11-18 l-SENS, INC. Polymer blend for controlling blood glucose influx, and continuous glucose monitoring biosensor comprising same
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CN112014448B (zh) * 2020-09-01 2023-02-17 深圳硅基传感科技有限公司 生物传感器及其制备方法以及生物传感器用的聚合物膜层
KR20230106671A (ko) 2020-11-20 2023-07-13 에프. 호프만-라 로슈 아게 플럭스 제한 중합체 막
EP4000517A1 (en) 2020-11-23 2022-05-25 Roche Diabetes Care GmbH Working electrode for an analyte sensor
US20230384255A1 (en) 2020-11-23 2023-11-30 Roche Diabetes Care, Inc. Method for preparing a working electrode
AU2021386164A1 (en) 2020-11-24 2023-06-08 F. Hoffmann-La Roche Ag Method for preparing a counter/reference electrode
EP4130729A1 (en) * 2021-08-04 2023-02-08 Roche Diabetes Care GmbH Opening formation in a membrane of a biosensor
EP4115806A1 (en) 2021-07-06 2023-01-11 Roche Diabetes Care GmbH Analyte sensor and method for manufacturing an analyte sensor
KR20240016431A (ko) 2021-07-06 2024-02-06 에프. 호프만-라 로슈 아게 분석물 센서 및 분석물 센서를 제조하는 방법
EP4140408A1 (en) 2021-08-30 2023-03-01 Roche Diabetes Care GmbH Membrane with biodegradable polymer
EP4151151A1 (en) 2021-09-21 2023-03-22 F. Hoffmann-La Roche AG Sensor with varying stiffness
WO2023122420A1 (en) 2021-12-24 2023-06-29 Roche Diabetes Care, Inc. Analyte sensor and method for manufacturing an analyte sensor
EP4212095A1 (en) 2022-01-18 2023-07-19 F. Hoffmann-La Roche AG Analyte sensor and method for manufacturing an analyte sensor
KR102389269B1 (ko) * 2022-02-16 2022-04-21 네메시스 주식회사 연속혈당측정 바이오센서용 글루코즈 확산 제어막 용액, 이를 포함하는 연속혈당측정 바이오센서용 글루코즈 확산 제어막 및 이를 포함하는 연속혈당측정용 바이오센서

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Also Published As

Publication number Publication date
PL2697388T3 (pl) 2015-11-30
HK1191984A1 (zh) 2014-08-08
WO2012130841A1 (en) 2012-10-04
IL234190B (en) 2019-09-26
BR112014021373B1 (pt) 2021-08-10
MX2013011041A (es) 2013-12-06
US20230258595A1 (en) 2023-08-17
US20140018653A1 (en) 2014-01-16
US10422765B2 (en) 2019-09-24
EP2697388B1 (en) 2015-05-20
AU2012234345A1 (en) 2013-09-05
ES2637811T3 (es) 2017-10-17
ES2707347T3 (es) 2019-04-03
KR20130122696A (ko) 2013-11-07
SI2697388T1 (sl) 2015-07-31
CN103443286B (zh) 2015-09-23
DK2831263T3 (en) 2017-09-25
US20150005605A1 (en) 2015-01-01
CN103443286A (zh) 2013-12-11
DK2697388T3 (en) 2015-08-31
HK1206793A1 (en) 2016-01-15
EP2697388A1 (en) 2014-02-19

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/03/2013, OBSERVADAS AS CONDICOES LEGAIS.