HK1190036A1 - 用於自體生物療法的系統和方法 - Google Patents
用於自體生物療法的系統和方法Info
- Publication number
- HK1190036A1 HK1190036A1 HK14103229.1A HK14103229A HK1190036A1 HK 1190036 A1 HK1190036 A1 HK 1190036A1 HK 14103229 A HK14103229 A HK 14103229A HK 1190036 A1 HK1190036 A1 HK 1190036A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- systems
- methods
- biological therapeutics
- autologous biological
- autologous
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/10—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by centrifugation ; Cyclones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
- A61M1/382—Optimisation of blood component yield
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Developmental Biology & Embryology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Ecology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161453658P | 2011-03-17 | 2011-03-17 | |
PCT/US2012/029379 WO2012125899A1 (en) | 2011-03-17 | 2012-03-16 | Systems and methods for autologous biological therapeutics |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1190036A1 true HK1190036A1 (zh) | 2014-06-27 |
Family
ID=46828640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK14103229.1A HK1190036A1 (zh) | 2011-03-17 | 2014-04-03 | 用於自體生物療法的系統和方法 |
Country Status (7)
Country | Link |
---|---|
US (3) | US9164079B2 (zh) |
EP (1) | EP2685816B1 (zh) |
JP (1) | JP6243227B2 (zh) |
CN (1) | CN103491771B (zh) |
ES (1) | ES2567603T3 (zh) |
HK (1) | HK1190036A1 (zh) |
WO (1) | WO2012125899A1 (zh) |
Families Citing this family (38)
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US9164079B2 (en) * | 2011-03-17 | 2015-10-20 | Greyledge Technologies Llc | Systems for autologous biological therapeutics |
EP2734621B1 (en) | 2011-07-22 | 2019-09-04 | President and Fellows of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
US9962480B2 (en) * | 2012-01-23 | 2018-05-08 | Estar Technologies Ltd | System and method for obtaining a cellular sample enriched with defined cells such as platelet rich plasma (PRP) |
US20140099287A1 (en) * | 2012-10-06 | 2014-04-10 | Spinesmith Partners, L.P. | Plasma protein concentrate for cell delivery in regenerative applications |
EP2733200A1 (en) * | 2012-11-15 | 2014-05-21 | Biorigen International SA | Cell culture supplements |
US9114190B2 (en) | 2013-02-08 | 2015-08-25 | Laser Spine Institute, Llc | Regeneration of spinal discs |
US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
US9840699B2 (en) | 2013-12-12 | 2017-12-12 | President And Fellows Of Harvard College | Methods for nucleic acid editing |
US9452199B2 (en) | 2014-01-17 | 2016-09-27 | General Electric Company | Platelet activation and growth factor release using electric pulses |
CA2956224A1 (en) | 2014-07-30 | 2016-02-11 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
US9816080B2 (en) | 2014-10-31 | 2017-11-14 | President And Fellows Of Harvard College | Delivery of CAS9 via ARRDC1-mediated microvesicles (ARMMs) |
GB201421013D0 (en) * | 2014-11-26 | 2015-01-07 | Turzi Antoine | New standardizations & medical devices for the preparation of platelet rich plasma (PRP) or bone marrow centrate (BMC) |
WO2016178914A1 (en) * | 2015-05-01 | 2016-11-10 | Cesca Therapeutics, Inc. | Intramuscular adaminstration of autologous bone marrw for treatment |
US10512659B2 (en) | 2015-07-02 | 2019-12-24 | Arthrex, Inc. | Methods and devices for preparation of enriched biological fluids |
US10167457B2 (en) | 2015-10-23 | 2019-01-01 | President And Fellows Of Harvard College | Nucleobase editors and uses thereof |
CN106215984B (zh) * | 2016-05-04 | 2018-07-13 | 大连理工大学 | 基于介电泳作用的微流控芯片 |
SG11201900907YA (en) | 2016-08-03 | 2019-02-27 | Harvard College | Adenosine nucleobase editors and uses thereof |
CN109804066A (zh) | 2016-08-09 | 2019-05-24 | 哈佛大学的校长及成员们 | 可编程cas9-重组酶融合蛋白及其用途 |
US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
SG11201903089RA (en) | 2016-10-14 | 2019-05-30 | Harvard College | Aav delivery of nucleobase editors |
US10745677B2 (en) | 2016-12-23 | 2020-08-18 | President And Fellows Of Harvard College | Editing of CCR5 receptor gene to protect against HIV infection |
WO2018165504A1 (en) | 2017-03-09 | 2018-09-13 | President And Fellows Of Harvard College | Suppression of pain by gene editing |
WO2018165629A1 (en) | 2017-03-10 | 2018-09-13 | President And Fellows Of Harvard College | Cytosine to guanine base editor |
US11268082B2 (en) | 2017-03-23 | 2022-03-08 | President And Fellows Of Harvard College | Nucleobase editors comprising nucleic acid programmable DNA binding proteins |
WO2018209320A1 (en) | 2017-05-12 | 2018-11-15 | President And Fellows Of Harvard College | Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation |
EP3658573A1 (en) | 2017-07-28 | 2020-06-03 | President and Fellows of Harvard College | Methods and compositions for evolving base editors using phage-assisted continuous evolution (pace) |
WO2019139645A2 (en) | 2017-08-30 | 2019-07-18 | President And Fellows Of Harvard College | High efficiency base editors comprising gam |
CN111757937A (zh) | 2017-10-16 | 2020-10-09 | 布罗德研究所股份有限公司 | 腺苷碱基编辑器的用途 |
RU2685687C1 (ru) * | 2017-12-11 | 2019-04-22 | Государственное бюджетное учреждение Санкт-Петербургский научно-исследовательский институт скорой помощи им. И.И. Джанелидзе Российской Федерации | Способ лечения остеоартроза коленного сустава |
EP4439582A3 (en) * | 2018-04-28 | 2024-10-16 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Method and system for analysing a blood sample |
ES2782723B2 (es) | 2019-03-13 | 2021-05-18 | Active Bioregeneration Tech Sl | Procedimiento para obtencion y conservacion de factores de crecimiento de alta pureza y sus usos |
BR112021018607A2 (pt) | 2019-03-19 | 2021-11-23 | Massachusetts Inst Technology | Métodos e composições para editar sequências de nucleotídeos |
EP3799896A1 (en) | 2019-10-04 | 2021-04-07 | Arthrex, Inc | Devices and methods for making therapeutic fluids |
JP2023525304A (ja) | 2020-05-08 | 2023-06-15 | ザ ブロード インスティテュート,インコーポレーテッド | 標的二本鎖ヌクレオチド配列の両鎖同時編集のための方法および組成物 |
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US8454548B2 (en) * | 2008-04-14 | 2013-06-04 | Haemonetics Corporation | System and method for plasma reduced platelet collection |
US8702637B2 (en) * | 2008-04-14 | 2014-04-22 | Haemonetics Corporation | System and method for optimized apheresis draw and return |
US20100112081A1 (en) | 2008-10-07 | 2010-05-06 | Bioparadox, Llc | Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities |
US8313954B2 (en) * | 2009-04-03 | 2012-11-20 | Biomet Biologics, Llc | All-in-one means of separating blood components |
CN102262090B (zh) | 2010-05-24 | 2012-09-12 | 北京普利生仪器有限公司 | 一种血小板聚集性和凝血因子的测定方法及设备 |
US9164079B2 (en) * | 2011-03-17 | 2015-10-20 | Greyledge Technologies Llc | Systems for autologous biological therapeutics |
US10493194B2 (en) * | 2012-10-23 | 2019-12-03 | Spinesmith Partners, L.P. | Automated device for point-of-care cell processing |
US20150335681A1 (en) * | 2014-05-22 | 2015-11-26 | Microaire Surgical Instruments, Llc | Biocomposites Having Viable Stem Cells and Platelets and Methods for Making and Using the Same |
-
2012
- 2012-03-15 US US13/421,728 patent/US9164079B2/en active Active
- 2012-03-16 ES ES12757514.0T patent/ES2567603T3/es active Active
- 2012-03-16 JP JP2013558201A patent/JP6243227B2/ja active Active
- 2012-03-16 CN CN201280018114.8A patent/CN103491771B/zh active Active
- 2012-03-16 WO PCT/US2012/029379 patent/WO2012125899A1/en active Application Filing
- 2012-03-16 EP EP12757514.0A patent/EP2685816B1/en active Active
-
2014
- 2014-04-03 HK HK14103229.1A patent/HK1190036A1/zh unknown
-
2015
- 2015-09-08 US US14/848,073 patent/US9840690B2/en active Active
-
2017
- 2017-12-10 US US15/836,884 patent/US20180100133A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2014517684A (ja) | 2014-07-24 |
US20180100133A1 (en) | 2018-04-12 |
EP2685816B1 (en) | 2015-12-30 |
WO2012125899A1 (en) | 2012-09-20 |
US9164079B2 (en) | 2015-10-20 |
ES2567603T3 (es) | 2016-04-25 |
US20120237490A1 (en) | 2012-09-20 |
JP6243227B2 (ja) | 2017-12-06 |
EP2685816A1 (en) | 2014-01-22 |
US9840690B2 (en) | 2017-12-12 |
EP2685816A4 (en) | 2014-10-01 |
US20150376564A1 (en) | 2015-12-31 |
CN103491771A (zh) | 2014-01-01 |
CN103491771B (zh) | 2015-12-09 |
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