SG11201401911XA - Systems and methods for biological analysis - Google Patents

Systems and methods for biological analysis

Info

Publication number
SG11201401911XA
SG11201401911XA SG11201401911XA SG11201401911XA SG11201401911XA SG 11201401911X A SG11201401911X A SG 11201401911XA SG 11201401911X A SG11201401911X A SG 11201401911XA SG 11201401911X A SG11201401911X A SG 11201401911XA SG 11201401911X A SG11201401911X A SG 11201401911XA
Authority
SG
Singapore
Prior art keywords
systems
methods
biological analysis
biological
analysis
Prior art date
Application number
SG11201401911XA
Inventor
Ronald Danehy
Gary Lim
Jacob Freudenthal
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of SG11201401911XA publication Critical patent/SG11201401911XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50851Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50855Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using modular assemblies of strips or of individual wells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50857Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using arrays or bundles of open capillaries for holding samples
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/12Well or multiwell plates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/38Caps; Covers; Plugs; Pouring means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0642Filling fluids into wells by specific techniques
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0684Venting, avoiding backpressure, avoid gas bubbles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/142Preventing evaporation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0819Microarrays; Biochips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0848Specific forms of parts of containers
    • B01L2300/0858Side walls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0893Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/161Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
SG11201401911XA 2011-09-30 2012-09-28 Systems and methods for biological analysis SG11201401911XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161541366P 2011-09-30 2011-09-30
PCT/US2012/058042 WO2013049659A2 (en) 2011-09-30 2012-09-28 Systems and methods for biological analysis

Publications (1)

Publication Number Publication Date
SG11201401911XA true SG11201401911XA (en) 2014-08-28

Family

ID=47178863

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201401911XA SG11201401911XA (en) 2011-09-30 2012-09-28 Systems and methods for biological analysis

Country Status (5)

Country Link
US (2) US9267170B2 (en)
EP (1) EP2760583B1 (en)
CN (1) CN104114280B (en)
SG (1) SG11201401911XA (en)
WO (1) WO2013049659A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2014268299A1 (en) * 2013-05-24 2016-01-21 Life Technologies Corporation Systems and Methods for Biological Analysis
ES2943159T3 (en) 2015-02-06 2023-06-09 Life Technologies Corp Optical instrument for biological analysis
US10429303B2 (en) * 2017-03-24 2019-10-01 International Business Machines Corporation Portable and autonomous, IoT enabled, optical measurement system
CN107586700A (en) * 2017-10-11 2018-01-16 华东医药(杭州)基因科技有限公司 Digital PCR container
US20210354126A1 (en) * 2018-12-07 2021-11-18 Ultima Genomics, Inc. Implementing barriers for controlled environments during sample processing and detection
CN110361365A (en) * 2019-02-03 2019-10-22 北京理工大学 A kind of scanning fluoroscopic imaging device and the portable QPCR device using it

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4731335A (en) * 1985-09-13 1988-03-15 Fisher Scientific Company Method for treating thin samples on a surface employing capillary flow
US6209589B1 (en) * 1996-10-21 2001-04-03 Smithkline Beecham Plc Apparatus and method for distributing beads
US6171780B1 (en) * 1997-06-02 2001-01-09 Aurora Biosciences Corporation Low fluorescence assay platforms and related methods for drug discovery
DE69930726T2 (en) * 1998-01-12 2007-01-25 Massachusetts Institute Of Technology, Cambridge METHOD AND DEVICE FOR MICROTEST PROCESSING
US6027873A (en) * 1999-03-19 2000-02-22 Genencor International, Inc. Multi-through hole testing plate for high throughput screening
JP2002010777A (en) 2000-06-30 2002-01-15 Precision System Science Co Ltd Reaction vessel, reactor and method for controlling temperature of reaction liquid
US20040018615A1 (en) * 2000-08-02 2004-01-29 Garyantes Tina K. Virtual wells for use in high throughput screening assays
US20030180191A1 (en) * 2000-09-18 2003-09-25 Hideyuki Suzuki Micro well array and method of sealing liquid using the micro well array
US6942836B2 (en) * 2001-10-16 2005-09-13 Applera Corporation System for filling substrate chambers with liquid
EP1608952B1 (en) * 2002-12-20 2016-08-10 Life Technologies Corporation Assay apparatus and method using microfluidic arrays
US20050030615A1 (en) * 2003-08-06 2005-02-10 Jiming Mei Measured array for slides
CA2554126A1 (en) * 2004-01-22 2005-08-04 Incom, Inc. Fiber optic interrogated microfluidic device
DK1773978T3 (en) * 2004-05-19 2014-05-26 Univ Pittsburgh Perfused, three-dimensional cell / tissue disease models
US7976795B2 (en) * 2006-01-19 2011-07-12 Rheonix, Inc. Microfluidic systems
EP1860060B1 (en) * 2006-05-22 2010-07-07 Micronas GMBH Apparatus for mixing microdroplets
US20080175757A1 (en) 2007-01-19 2008-07-24 Andrew Powell Microarray device with elastomeric well structure
WO2009111696A1 (en) * 2008-03-06 2009-09-11 Biotrove, Inc. Devices and methods for thermally-mediated chemical reactions
CN201535776U (en) * 2009-02-09 2010-07-28 马义才 Quantitative detection system based on test strip marked with constantly illuminating material
CN201581079U (en) * 2009-11-20 2010-09-15 宁波普赛微流科技有限公司 Polymerase chain reaction-capillary electrophoresis combined micro-fluidic chip laser-induced fluorescence analyzing device

Also Published As

Publication number Publication date
WO2013049659A2 (en) 2013-04-04
US9267170B2 (en) 2016-02-23
EP2760583A2 (en) 2014-08-06
EP2760583B1 (en) 2020-05-06
US20160168626A1 (en) 2016-06-16
CN104114280B (en) 2017-05-17
WO2013049659A3 (en) 2013-07-04
US10385383B2 (en) 2019-08-20
US20140242596A1 (en) 2014-08-28
CN104114280A (en) 2014-10-22

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