HK1187678A1 - 測定心律失常的風險的方法 - Google Patents

測定心律失常的風險的方法

Info

Publication number
HK1187678A1
HK1187678A1 HK14100686.3A HK14100686A HK1187678A1 HK 1187678 A1 HK1187678 A1 HK 1187678A1 HK 14100686 A HK14100686 A HK 14100686A HK 1187678 A1 HK1187678 A1 HK 1187678A1
Authority
HK
Hong Kong
Prior art keywords
arrythmia
determining risk
risk
determining
Prior art date
Application number
HK14100686.3A
Other languages
English (en)
Inventor
Rory Abrams
Joshua Babiarz
Eric Chiao
Liang Guo
Kyle L Kolaja
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1187678A1 publication Critical patent/HK1187678A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5061—Muscle cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • G01N27/12—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon absorption of a fluid; of a solid body in dependence upon reaction with a fluid, for detecting components in the fluid
    • G01N27/128—Microapparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/326—Arrhythmias, e.g. ventricular fibrillation, tachycardia, atrioventricular block, torsade de pointes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
HK14100686.3A 2010-10-29 2014-01-22 測定心律失常的風險的方法 HK1187678A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40793110P 2010-10-29 2010-10-29
US41536810P 2010-11-19 2010-11-19
PCT/EP2011/068579 WO2012055828A1 (en) 2010-10-29 2011-10-25 Method of determining risk of arrythmia

Publications (1)

Publication Number Publication Date
HK1187678A1 true HK1187678A1 (zh) 2014-04-11

Family

ID=45001708

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14100686.3A HK1187678A1 (zh) 2010-10-29 2014-01-22 測定心律失常的風險的方法

Country Status (11)

Country Link
US (2) US20120107861A1 (zh)
EP (1) EP2633322B1 (zh)
JP (1) JP6133210B2 (zh)
KR (2) KR20130079566A (zh)
CN (1) CN103221826B (zh)
BR (1) BR112013009888A2 (zh)
CA (1) CA2815108A1 (zh)
HK (1) HK1187678A1 (zh)
MX (1) MX2013004351A (zh)
RU (1) RU2583941C2 (zh)
WO (1) WO2012055828A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014122302A1 (en) * 2013-02-08 2014-08-14 Ruprecht-Karls-Universität Heidelberg In vitro method for cardiovascular risk stratification
KR101617683B1 (ko) * 2015-01-09 2016-05-03 연세대학교 산학협력단 부정맥 치료제 효과 평가 시스템 및 방법
US9983198B2 (en) 2015-03-19 2018-05-29 Axion Biosystems, Inc. Systems and methods for assessing data collected from an electrically active cell culture
CA3089957C (en) * 2017-02-04 2024-01-23 AnaBios Corporation System and methods for predicting drug-induced inotropic and pro-arrhythmia risk
US20200240980A1 (en) * 2017-10-12 2020-07-30 The Research Foundation For The State University Of New York Method for delayed rectifier current enhancement, characterization, and analysis in human induced pluripotent stem cells
JP7341478B2 (ja) * 2017-12-26 2023-09-11 株式会社マイオリッジ 心筋細胞の薬剤応答性試験方法
US20220257665A1 (en) * 2019-06-06 2022-08-18 Novo Nordisk A/S Application of antiarrhythmic agents to stem cell derived cardiomyocytes and uses thereof
WO2022004963A1 (ko) * 2020-07-02 2022-01-06 주식회사 티앤알바이오팹 인간 전분화능줄기세포 유래 심근세포를 이용한 SARS-CoV-2 바이러스 대상 후보 약물의 부정맥 위험성 평가용 조성물 및 이를 이용한 부정맥 위험성 평가 방법
KR102590512B1 (ko) * 2021-04-19 2023-10-16 건국대학교 글로컬산학협력단 인간 유도만능줄기세포 유래 심근세포 및 다중전극 분석을 이용한 이중-심장독성평가 방법
WO2022255532A1 (ko) * 2021-06-01 2022-12-08 주식회사 티앤알바이오팹 인간 전분화능줄기세포 유래 심근세포를 이용한 약물의 부정맥 위험성 평가 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1301414A1 (ru) * 1985-09-27 1987-04-07 Научно-Исследовательский Институт По Биологическим Испытаниям Химических Соединений Способ определени индивидуальной чувствительности к кардиотропному препарату
EP1551991A4 (en) * 2002-07-26 2006-09-20 Wisconsin Alumni Res Found FUNCTIONAL HEART MUSCLE CELLS FROM HUMAN EMBRYONAL STEM CELLS
US20050009006A1 (en) * 2003-05-09 2005-01-13 Ofer Binah High throughput monitoring chamber for testing drug effects on repolarization and conduction
JP4814875B2 (ja) * 2004-05-11 2011-11-16 アキシオジェネシス エージー ｉｎｖｉｔｒｏ分化細胞に基づく薬物発見のための検定
US7813792B2 (en) * 2006-04-17 2010-10-12 General Electric Company Method and apparatus for analyzing and editing ECG morphology and time series
WO2009038079A1 (ja) * 2007-09-18 2009-03-26 Biotec Co., Ltd. 細胞測定容器、細胞外電位測定方法、薬品検査方法
JP2009244197A (ja) * 2008-03-31 2009-10-22 Hioki Ee Corp 薬剤感受性試験方法及び装置
CA2723223C (en) * 2008-05-05 2017-06-06 Acea Biosciences, Inc. Label-free monitoring of excitation-contraction coupling and excitable cells using impedance based systems with millisecond time resolution

Also Published As

Publication number Publication date
EP2633322A1 (en) 2013-09-04
JP2013543726A (ja) 2013-12-09
US20120107861A1 (en) 2012-05-03
RU2013123513A (ru) 2014-12-10
CA2815108A1 (en) 2012-05-03
MX2013004351A (es) 2013-06-07
JP6133210B2 (ja) 2017-05-24
WO2012055828A1 (en) 2012-05-03
KR20130079566A (ko) 2013-07-10
BR112013009888A2 (pt) 2021-07-20
CN103221826A (zh) 2013-07-24
KR20160022393A (ko) 2016-02-29
EP2633322B1 (en) 2018-02-14
KR101774182B1 (ko) 2017-09-01
RU2583941C2 (ru) 2016-05-10
US20170241987A1 (en) 2017-08-24
CN103221826B (zh) 2016-02-03

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20201024