HK1179274A1 - Intermediate for synthesizing caspofungin and preparation method for therefor - Google Patents

Intermediate for synthesizing caspofungin and preparation method for therefor

Info

Publication number
HK1179274A1
HK1179274A1 HK13106387.3A HK13106387A HK1179274A1 HK 1179274 A1 HK1179274 A1 HK 1179274A1 HK 13106387 A HK13106387 A HK 13106387A HK 1179274 A1 HK1179274 A1 HK 1179274A1
Authority
HK
Hong Kong
Prior art keywords
therefor
preparation
caspofungin
synthesizing
synthesizing caspofungin
Prior art date
Application number
HK13106387.3A
Other languages
English (en)
Chinese (zh)
Inventor
張富堯
神小明
胡高强
孫飄揚
Original Assignee
上海源力生物技術有限公司 上海市浦東新區 號樓
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 上海源力生物技術有限公司 上海市浦東新區 號樓 filed Critical 上海源力生物技術有限公司 上海市浦東新區 號樓
Publication of HK1179274A1 publication Critical patent/HK1179274A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
HK13106387.3A 2011-04-28 2013-05-29 Intermediate for synthesizing caspofungin and preparation method for therefor HK1179274A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110107633 2011-04-28
PCT/CN2012/072714 WO2012146099A1 (zh) 2011-04-28 2012-03-21 用于合成卡帕芬净的中间体及其制备方法

Publications (1)

Publication Number Publication Date
HK1179274A1 true HK1179274A1 (en) 2013-09-27

Family

ID=47071596

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13106387.3A HK1179274A1 (en) 2011-04-28 2013-05-29 Intermediate for synthesizing caspofungin and preparation method for therefor

Country Status (13)

Country Link
US (1) US9321779B2 (xx)
EP (1) EP2703409B1 (xx)
JP (1) JP6032822B2 (xx)
KR (1) KR20140042805A (xx)
CN (1) CN103003295B (xx)
AU (1) AU2012248013B2 (xx)
BR (1) BR112013026868A2 (xx)
CA (1) CA2833206A1 (xx)
HK (1) HK1179274A1 (xx)
MX (1) MX2013012161A (xx)
RU (1) RU2592280C2 (xx)
TW (1) TWI597293B (xx)
WO (1) WO2012146099A1 (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9636407B2 (en) 2012-11-20 2017-05-02 Fresenius Kabi Usa, Llc Caspofungin acetate formulations
CN109721641B (zh) * 2017-10-31 2021-08-03 鲁南制药集团股份有限公司 一种卡泊芬净的合成方法
CN111233981A (zh) * 2020-03-17 2020-06-05 湖南欧亚药业有限公司 一种卡泊芬净的制备方法
CN113801202A (zh) * 2020-06-15 2021-12-17 杭州中美华东制药有限公司 一种醋酸卡泊芬净杂质g的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378804A (en) 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5552521A (en) * 1995-02-10 1996-09-03 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
US5936062A (en) 1997-06-12 1999-08-10 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
AR035808A1 (es) * 2001-04-12 2004-07-14 Merck & Co Inc Proceso de deshidratacion capaz de minimizar la epimerizacion de un grupo hidroxilo por ciertas equinocandinas
EP1785432A1 (en) * 2005-11-15 2007-05-16 Sandoz AG Process and intermediates for the synthesis of caspofungin.
TW201024322A (en) 2008-12-31 2010-07-01 Chunghwa Chemical Synthesis & Biotech Co Ltd Preparation method for nitrogen containing heterocyclic hexapeptide with high conversion rate
US9006391B2 (en) * 2009-05-07 2015-04-14 Dsm Sinochem Pharmaceuticals Netherlands B.V. Method for the preparation of cyclopeptides
WO2011014990A1 (zh) * 2009-08-06 2011-02-10 上海天伟生物制药有限公司 一种氮杂环己肽或其药学上可接受的盐及其制备方法和用途
CN101648994B (zh) * 2009-08-06 2012-09-05 上海天伟生物制药有限公司 一种氮杂环己肽或其药学上可接受的盐及其制备方法和用途
CN101792486A (zh) 2010-04-12 2010-08-04 浙江海正药业股份有限公司 一种合成醋酸卡泊芬净的方法
KR101331984B1 (ko) 2010-12-09 2013-11-25 종근당바이오 주식회사 카스포펀진 제조방법 및 그의 신규 중간체
EP2661441A4 (en) * 2011-01-03 2015-04-08 Biocon Ltd PROCESS FOR THE PREPARATION OF ACETATE CASPOFUNGIN AND ITS INTERMEDIATES

Also Published As

Publication number Publication date
JP2014513087A (ja) 2014-05-29
JP6032822B2 (ja) 2016-11-30
US9321779B2 (en) 2016-04-26
MX2013012161A (es) 2014-07-30
TW201309732A (zh) 2013-03-01
EP2703409B1 (en) 2017-01-18
WO2012146099A1 (zh) 2012-11-01
RU2592280C2 (ru) 2016-07-20
BR112013026868A2 (pt) 2016-09-06
CA2833206A1 (en) 2012-11-01
TWI597293B (zh) 2017-09-01
RU2013150969A (ru) 2015-11-10
EP2703409A1 (en) 2014-03-05
US20140058082A1 (en) 2014-02-27
EP2703409A4 (en) 2014-10-29
AU2012248013B2 (en) 2016-07-14
AU2012248013A1 (en) 2013-11-14
CN103003295A (zh) 2013-03-27
CN103003295B (zh) 2014-09-17
KR20140042805A (ko) 2014-04-07

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20220317