HK1177889A1 - Therapeutic combination comprising a cdc7 inhibitor and an antineoplastic agent cdc7 - Google Patents

Therapeutic combination comprising a cdc7 inhibitor and an antineoplastic agent cdc7

Info

Publication number
HK1177889A1
HK1177889A1 HK13104963.0A HK13104963A HK1177889A1 HK 1177889 A1 HK1177889 A1 HK 1177889A1 HK 13104963 A HK13104963 A HK 13104963A HK 1177889 A1 HK1177889 A1 HK 1177889A1
Authority
HK
Hong Kong
Prior art keywords
cdc7
antineoplastic agent
therapeutic combination
inhibitor
cdc7 inhibitor
Prior art date
Application number
HK13104963.0A
Other languages
English (en)
Chinese (zh)
Inventor
．巴裡納利
．希亞沃雷拉
．派森蒂
．蒙塔尼奧利
Original Assignee
內爾維阿諾醫學科學有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 內爾維阿諾醫學科學有限公司 filed Critical 內爾維阿諾醫學科學有限公司
Publication of HK1177889A1 publication Critical patent/HK1177889A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK13104963.0A 2009-11-18 2013-04-24 Therapeutic combination comprising a cdc7 inhibitor and an antineoplastic agent cdc7 HK1177889A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09176370 2009-11-18
PCT/EP2010/067675 WO2011061222A1 (en) 2009-11-18 2010-11-17 Therapeutic combination comprising a cdc7 inhibitor and an antineoplastic agent

Publications (1)

Publication Number Publication Date
HK1177889A1 true HK1177889A1 (en) 2013-08-30

Family

ID=43501061

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13104963.0A HK1177889A1 (en) 2009-11-18 2013-04-24 Therapeutic combination comprising a cdc7 inhibitor and an antineoplastic agent cdc7

Country Status (9)

Country Link
US (1) US9119877B2 (xx)
EP (1) EP2501385B1 (xx)
JP (1) JP2013511487A (xx)
CN (1) CN102753176B (xx)
AR (1) AR079049A1 (xx)
ES (1) ES2625492T3 (xx)
HK (1) HK1177889A1 (xx)
TW (1) TW201127384A (xx)
WO (1) WO2011061222A1 (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101964479B1 (ko) 2011-03-31 2019-04-01 카나 바이오사이언스, 인코포레이션 신규 푸라논 유도체
EP2736514B1 (en) * 2011-07-28 2017-10-18 Nerviano Medical Sciences S.r.l. Alkynyl substituted pyrimidinyl-pyrroles active as kinases inhibitors
WO2015116735A1 (en) 2014-01-28 2015-08-06 Mayo Foundation For Medical Education And Research Methods and combinations for killing senescent cells and for treating senescence-associated diseases and disorders
US10328058B2 (en) 2014-01-28 2019-06-25 Mayo Foundation For Medical Education And Research Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaques
CA3100140C (en) 2014-01-28 2023-10-24 Buck Institute For Research On Aging Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders
EP3100742B1 (en) 2014-01-31 2020-05-20 Carna Biosciences Inc. Anticancer agent composition comprising a cdc7 inhibitor and a wee1 inhibitor
WO2019165473A1 (en) * 2018-02-26 2019-08-29 Sierra Oncology, Inc Methods of treatment of cancer comprising cdc7 inhibitors
GB201807147D0 (en) * 2018-05-01 2018-06-13 Oncologica Uk Ltd Therapeutic combination

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750737A (en) * 1996-09-25 1998-05-12 Sisti; Nicholas J. Method for paclitaxel synthesis
TWI394749B (zh) * 2006-03-27 2013-05-01 內維亞諾醫學公司 具有激酶抑制劑活性之雜戊環
TWI426074B (zh) * 2008-04-30 2014-02-11 Nerviano Medical Sciences Srl ５－（２－胺基－嘧啶－４－基）－２－芳基－１ｈ－吡咯－３－羧醯胺之製造方法

Also Published As

Publication number Publication date
AR079049A1 (es) 2011-12-21
ES2625492T3 (es) 2017-07-19
CN102753176B (zh) 2014-07-16
US9119877B2 (en) 2015-09-01
CN102753176A (zh) 2012-10-24
EP2501385B1 (en) 2017-03-01
TW201127384A (en) 2011-08-16
US20120276093A1 (en) 2012-11-01
WO2011061222A1 (en) 2011-05-26
JP2013511487A (ja) 2013-04-04
EP2501385A1 (en) 2012-09-26

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