HK1177229A1 - Marker consisting of plasma microrna and new method for diagnosis of hepatocellular carcinoma - Google Patents

Marker consisting of plasma microrna and new method for diagnosis of hepatocellular carcinoma

Info

Publication number
HK1177229A1
HK1177229A1 HK13104815.0A HK13104815A HK1177229A1 HK 1177229 A1 HK1177229 A1 HK 1177229A1 HK 13104815 A HK13104815 A HK 13104815A HK 1177229 A1 HK1177229 A1 HK 1177229A1
Authority
HK
Hong Kong
Prior art keywords
diagnosis
new method
hepatocellular carcinoma
marker consisting
plasma microrna
Prior art date
Application number
HK13104815.0A
Other languages
English (en)
Inventor
Jia Fan
Jian Zhou
Zhi Dai
Lei Yu
Jie Hu
Zheng Wang
Original Assignee
Zhongshan Hospital Fudan Univ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhongshan Hospital Fudan Univ filed Critical Zhongshan Hospital Fudan Univ
Publication of HK1177229A1 publication Critical patent/HK1177229A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK13104815.0A 2011-05-06 2013-04-22 Marker consisting of plasma microrna and new method for diagnosis of hepatocellular carcinoma HK1177229A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2011/073774 WO2012151736A1 (fr) 2011-05-06 2011-05-06 Marqueur constitué d'un microarn du plasma et nouvelle méthode de diagnostic d'un carcinome hépatocellulaire

Publications (1)

Publication Number Publication Date
HK1177229A1 true HK1177229A1 (en) 2013-08-30

Family

ID=47138644

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13104815.0A HK1177229A1 (en) 2011-05-06 2013-04-22 Marker consisting of plasma microrna and new method for diagnosis of hepatocellular carcinoma

Country Status (6)

Country Link
US (1) US20130237456A1 (fr)
EP (1) EP2596136B1 (fr)
JP (1) JP5753905B2 (fr)
KR (1) KR101532210B1 (fr)
HK (1) HK1177229A1 (fr)
WO (1) WO2012151736A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6837838B2 (ja) * 2014-06-18 2021-03-03 東レ株式会社 肝臓がんの検出キット又はデバイス及び検出方法
EP3233119A2 (fr) 2014-12-18 2017-10-25 Bergen Teknologioverforing AS Anticorps antagonistes anti-axl
US11339440B2 (en) 2018-09-20 2022-05-24 Tamirna Gmbh Micro-RNA signatures for the prediction of liver dysfunction
JP7058612B2 (ja) 2019-01-10 2022-04-22 株式会社丸山製作所 防振装置を備えた動力作業機及び背負式動力作業機
CN111235271A (zh) * 2019-12-12 2020-06-05 中山大学附属第三医院 基于指导肝细胞癌的精准治疗中的应用及用于试剂盒
CN113186224B (zh) * 2021-04-29 2023-01-10 中国人民解放军陆军军医大学士官学校 具有抑制乙肝病毒复制活性的microRNA-27a及其应用
CN113755597B (zh) * 2021-10-14 2022-12-06 杭州师范大学 外周血外泌体miRNA联合标志物在制备检测HBV阳性肝硬化早期肝癌试剂盒中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE180489T1 (de) * 1989-12-19 1999-06-15 Us Health Für leberzellkarzinom spezifisches onkogen
CA2667617A1 (fr) * 2006-11-01 2008-05-08 The Ohio State University Research Foundation Signature de l'expression de microarn pour la prediction de la survie et des metastases dans le carcinome hepato-cellulaire
CA2699646A1 (fr) * 2007-09-14 2009-03-19 The Ohio State University Research Foundation Expression de arnmi dans des microvesicules sanguines peripheriques humains et utilisations de celle-ci
JP5116026B2 (ja) * 2008-01-23 2013-01-09 富士フイルム株式会社 癌の検出方法および癌抑制剤
CN101368213A (zh) * 2008-10-13 2009-02-18 南京大学 血清微小核糖核酸试剂盒及其在乙肝早期诊断中的应用
WO2010055488A2 (fr) * 2008-11-13 2010-05-20 Koninklijke Philips Electronics N.V. Compositions et procédés pour le profilage de l’expression des microarn du cancer hépatocellulaire
ITMI20091538A1 (it) * 2009-09-07 2011-03-08 Istituto Naz Di Genetica Mole Colare Ingm Profili di espressione di micro-rna nel sangue periferico di pazienti affetti da epatocarcinoma o cirrosi epatica e loro usi
CN102021169A (zh) * 2010-10-14 2011-04-20 南京大学 一种血清/血浆miRNA组合物及其应用

Also Published As

Publication number Publication date
JP5753905B2 (ja) 2015-07-22
EP2596136A4 (fr) 2013-12-25
EP2596136B1 (fr) 2014-07-16
KR101532210B1 (ko) 2015-06-29
EP2596136A1 (fr) 2013-05-29
US20130237456A1 (en) 2013-09-12
WO2012151736A1 (fr) 2012-11-15
JP2013538583A (ja) 2013-10-17
KR20130029079A (ko) 2013-03-21

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