HK1172320A1 - Novel biphenyl and phenyl pyridine amides - Google Patents
Novel biphenyl and phenyl pyridine amidesInfo
- Publication number
- HK1172320A1 HK1172320A1 HK12113110.4A HK12113110A HK1172320A1 HK 1172320 A1 HK1172320 A1 HK 1172320A1 HK 12113110 A HK12113110 A HK 12113110A HK 1172320 A1 HK1172320 A1 HK 1172320A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- phenyl pyridine
- novel biphenyl
- pyridine amides
- amides
- biphenyl
- Prior art date
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- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
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- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21901609P | 2009-06-22 | 2009-06-22 | |
PCT/EP2010/058611 WO2010149578A2 (en) | 2009-06-22 | 2010-06-18 | Novel biphenyl and phenyl-pyridine amides |
Publications (1)
Publication Number | Publication Date |
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HK1172320A1 true HK1172320A1 (en) | 2013-04-19 |
Family
ID=43127140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK12113110.4A HK1172320A1 (en) | 2009-06-22 | 2012-12-19 | Novel biphenyl and phenyl pyridine amides |
Country Status (9)
Country | Link |
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US (4) | US8283383B2 (xx) |
EP (1) | EP2445868B1 (xx) |
JP (1) | JP5476467B2 (xx) |
CN (1) | CN102574778B (xx) |
CA (1) | CA2764956A1 (xx) |
ES (1) | ES2450891T3 (xx) |
HK (1) | HK1172320A1 (xx) |
SG (1) | SG177308A1 (xx) |
WO (1) | WO2010149578A2 (xx) |
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CA2715835C (en) | 2008-02-29 | 2017-03-21 | Renovis, Inc. | Amide compounds, compositions and uses thereof |
JP5608655B2 (ja) | 2008-09-18 | 2014-10-15 | エヴォテック アーゲー | P2x3受容体活性のモジュレーター |
PL2399910T3 (pl) | 2009-02-13 | 2014-09-30 | Shionogi & Co | Pochodne triazyny jako antagoniści receptora p2x3 i/albo p2x2/3 i kompozycja farmaceutyczna zawierająca je |
ES2593405T3 (es) * | 2009-06-22 | 2016-12-09 | F. Hoffmann-La Roche Ag | Nuevas arilamidas sustituidas por benzoxazolona |
SG177308A1 (en) * | 2009-06-22 | 2012-02-28 | Hoffmann La Roche | Novel biphenyl and phenyl-pyridine amides |
RU2565073C2 (ru) | 2010-08-10 | 2015-10-20 | Сионоги Энд Ко., Лтд. | Триазиновое производное и включающая его фармацевтическая композиция, обладающая анальгетической активностью |
JP5951650B2 (ja) | 2011-03-18 | 2016-07-13 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH | N−(3−カルバモイルフェニル)−1h−ピラゾール−5−カルボキサミド誘導体及び害虫を防除するためのそれらの使用 |
JP6124351B2 (ja) | 2012-02-09 | 2017-05-10 | 塩野義製薬株式会社 | 複素環および炭素環誘導体 |
CA2903572A1 (en) * | 2013-03-15 | 2014-10-23 | Epizyme, Inc. | Substituted benzene compounds |
US9243001B2 (en) | 2013-03-15 | 2016-01-26 | Epizyme, Inc. | Substituted benzene compounds |
TWI637949B (zh) | 2013-06-14 | 2018-10-11 | 塩野義製藥股份有限公司 | 胺基三衍生物及含有其等之醫藥組合物 |
AU2015359626B2 (en) | 2014-12-09 | 2020-07-23 | Bayer Aktiengesellschaft | 1,3-thiazol-2-yl substituted benzamides |
US10183937B2 (en) | 2014-12-09 | 2019-01-22 | Bayer Aktiengesellschaft | 1,3-thiazol-2-yl substituted benzamides |
AU2020348089A1 (en) | 2019-09-19 | 2022-03-31 | Shionogi & Co., Ltd. | Crystal of 1,3,5-triazine derivative or solvate thereof and method for producing same |
AU2021282039A1 (en) * | 2020-05-25 | 2022-12-01 | The National Institutes of Pharmaceutical R&D Co., Ltd. | Arylformamide compound and preparation method and medical use thereof |
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FR2673180B1 (fr) * | 1991-02-25 | 1994-03-04 | Guerbet Sa | Nouveaux composes non ioniques poly-iodes, procede de preparation, produit de contraste les contenant. |
IL109570A0 (en) | 1993-05-17 | 1994-08-26 | Fujisawa Pharmaceutical Co | Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
US6380187B2 (en) | 1999-03-25 | 2002-04-30 | Dingwei Tim Yu | Class of thiomorpholino substituted thiazoles |
EP1194421B1 (en) | 1999-06-30 | 2005-10-12 | H. Lundbeck A/S | Selective npy (y5) antagonists |
MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
JP5230052B2 (ja) | 2000-05-26 | 2013-07-10 | イデニクス(ケイマン)リミテツド | フラビウイルスおよびペスチウイルス治療のための方法および組成物 |
CA2409762A1 (en) | 2000-06-23 | 2002-01-03 | Donald J.P. Pinto | Heteroaryl-phenyl substituted factor xa inhibitors |
DE10055713A1 (de) | 2000-11-10 | 2002-05-23 | Dingwei Tim Yu | Neue Klasse von Antifungimitteln |
EP1539188B1 (en) | 2001-01-22 | 2015-01-07 | Merck Sharp & Dohme Corp. | Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase |
US20030236439A1 (en) | 2002-01-30 | 2003-12-25 | Gregory Agoston | Non-steroidal analogs of 2-methoxyestradiol |
US20060058553A1 (en) * | 2002-02-07 | 2006-03-16 | Axys Pharmaceuticals, Inc. | Novel bicyclic hydroxamates as inhibitors of histone deacetylase |
GB0212785D0 (en) * | 2002-05-31 | 2002-07-10 | Glaxo Group Ltd | Compounds |
EP1515971A2 (en) | 2002-06-17 | 2005-03-23 | Merck & Co., Inc. | Carbocyclic nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase |
WO2004002422A2 (en) | 2002-06-28 | 2004-01-08 | Idenix (Cayman) Limited | 2’-c-methyl-3’-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections |
TW200500374A (en) | 2002-06-28 | 2005-01-01 | Idenlx Cayman Ltd | 2' and 3' -nucleoside produrgs for treating flavivridae infections |
EP1523556A1 (en) | 2002-07-18 | 2005-04-20 | Sri International | Methods of treating conditions associated with an edg-1 receptor |
CA2506129C (en) | 2002-11-15 | 2015-02-17 | Idenix (Cayman) Limited | 2'-branched nucleosides and flaviviridae mutation |
TWI332507B (en) | 2002-11-19 | 2010-11-01 | Hoffmann La Roche | Antiviral nucleoside derivatives |
US20070043512A1 (en) | 2003-03-26 | 2007-02-22 | Michael Rolph | Therapeutic and prophylactic compositions and uses therefor |
CN1805945A (zh) | 2003-04-18 | 2006-07-19 | 麦克公司 | 作为钠通道阻滞剂的联芳基取代的噻唑、噁唑和咪唑 |
BRPI0410349A (pt) | 2003-05-12 | 2006-05-30 | Pfizer Prod Inc | inibidores de benzamida do receptor p2x7 |
WO2005020885A2 (en) | 2003-05-21 | 2005-03-10 | Isis Pharmaceuticals, Inc. | Compositions and methods for the treatment of severe acute respiratory syndrome (sars) |
WO2005009418A2 (en) | 2003-07-25 | 2005-02-03 | Idenix (Cayman) Limited | Purine nucleoside analogues for treating diseases caused by flaviviridae including hepatitis c |
AU2006218404A1 (en) * | 2005-03-03 | 2006-09-08 | Sirtris Pharmaceuticals, Inc. | N-phenyl benzamide derivatives as sirtuin modulators |
JP4987871B2 (ja) | 2005-08-15 | 2012-07-25 | エフ.ホフマン−ラ ロシュ アーゲー | P2x3アンタゴニストとしてのピペリジン及びピペラジン誘導体 |
CA2654915C (en) * | 2006-06-29 | 2015-07-28 | F.Hoffmann-La Roche Ag | Tetrazole-substituted arylamides |
TWI389895B (zh) * | 2006-08-21 | 2013-03-21 | Infinity Discovery Inc | 抑制bcl蛋白質與結合夥伴間之交互作用的化合物及方法 |
JP5084839B2 (ja) | 2006-11-09 | 2012-11-28 | エフ.ホフマン−ラ ロシュ アーゲー | チアゾール及びオキサゾール置換アリールアミド |
AU2008319309B2 (en) | 2007-10-31 | 2012-09-06 | Merck Sharp & Dohme Llc | P2X3 receptor antagonists for treatment of pain |
JP2011502148A (ja) | 2007-10-31 | 2011-01-20 | メルク・シャープ・エンド・ドーム・コーポレイション | 疼痛の治療用としてのp2x3受容体アンタゴニスト |
CA2707422C (en) | 2007-12-17 | 2016-06-07 | F. Hoffmann-La Roche Ag | Triazole-substituted arylamide derivatives and their use as p2x3 and /or p2x2/3 purinergic receptor antagonists |
WO2009077365A1 (en) | 2007-12-17 | 2009-06-25 | F. Hoffmann-La Roche Ag | Novel imidazole-substituted arylamides |
WO2009077371A1 (en) | 2007-12-17 | 2009-06-25 | F. Hoffmann-La Roche Ag | Tetrazole-substituted arylamide derivatives and their use as p2x3 and/or p2x2/3 purinergic receptor antagonists |
WO2009077367A1 (en) | 2007-12-17 | 2009-06-25 | F. Hoffmann-La Roche Ag | Novel pyrazole-substituted arylamides |
US8048887B2 (en) * | 2008-09-11 | 2011-11-01 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
SG177301A1 (en) | 2009-06-22 | 2012-02-28 | Hoffmann La Roche | Novel indole, indazole and benzimidazole arylamides as p2x3 and/or p2x2/3 antagonists |
SG177308A1 (en) * | 2009-06-22 | 2012-02-28 | Hoffmann La Roche | Novel biphenyl and phenyl-pyridine amides |
ES2593405T3 (es) | 2009-06-22 | 2016-12-09 | F. Hoffmann-La Roche Ag | Nuevas arilamidas sustituidas por benzoxazolona |
-
2010
- 2010-06-18 SG SG2011094877A patent/SG177308A1/en unknown
- 2010-06-18 WO PCT/EP2010/058611 patent/WO2010149578A2/en active Application Filing
- 2010-06-18 JP JP2012516659A patent/JP5476467B2/ja not_active Expired - Fee Related
- 2010-06-18 CN CN201080027808.9A patent/CN102574778B/zh not_active Expired - Fee Related
- 2010-06-18 EP EP10725188.6A patent/EP2445868B1/en active Active
- 2010-06-18 CA CA2764956A patent/CA2764956A1/en active Pending
- 2010-06-18 ES ES10725188.6T patent/ES2450891T3/es active Active
- 2010-06-22 US US12/820,577 patent/US8283383B2/en active Active
-
2012
- 2012-08-23 US US13/592,625 patent/US8895589B2/en active Active
- 2012-12-19 HK HK12113110.4A patent/HK1172320A1/xx not_active IP Right Cessation
-
2014
- 2014-11-19 US US14/547,632 patent/US9505726B2/en active Active
-
2016
- 2016-11-09 US US15/347,614 patent/US20170057932A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20100324056A1 (en) | 2010-12-23 |
CN102574778B (zh) | 2015-01-07 |
US20150080408A1 (en) | 2015-03-19 |
ES2450891T3 (es) | 2014-03-25 |
SG177308A1 (en) | 2012-02-28 |
US20130165443A1 (en) | 2013-06-27 |
US20170057932A1 (en) | 2017-03-02 |
EP2445868B1 (en) | 2013-12-18 |
WO2010149578A3 (en) | 2011-07-14 |
US8895589B2 (en) | 2014-11-25 |
EP2445868A2 (en) | 2012-05-02 |
US9505726B2 (en) | 2016-11-29 |
WO2010149578A2 (en) | 2010-12-29 |
JP5476467B2 (ja) | 2014-04-23 |
JP2012530750A (ja) | 2012-12-06 |
US8283383B2 (en) | 2012-10-09 |
CN102574778A (zh) | 2012-07-11 |
CA2764956A1 (en) | 2010-12-29 |
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PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190616 |