HK1171024A1 - 用於表達 多肽的癌症的肽疫苗 - Google Patents

用於表達 多肽的癌症的肽疫苗

Info

Publication number
HK1171024A1
HK1171024A1 HK12111314.2A HK12111314A HK1171024A1 HK 1171024 A1 HK1171024 A1 HK 1171024A1 HK 12111314 A HK12111314 A HK 12111314A HK 1171024 A1 HK1171024 A1 HK 1171024A1
Authority
HK
Hong Kong
Prior art keywords
mphosph1
polypeptides
peptide vaccines
cancers expressing
cancers
Prior art date
Application number
HK12111314.2A
Other languages
English (en)
Inventor
Tomoaki Fujioka
Yusuke Nakamura
Takuya Tsunoda
Ryuji Osawa
Midori Shida
Original Assignee
Oncotherapy Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncotherapy Science Inc filed Critical Oncotherapy Science Inc
Publication of HK1171024A1 publication Critical patent/HK1171024A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Reproductive Health (AREA)
  • Physics & Mathematics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
HK12111314.2A 2006-10-17 2009-11-23 用於表達 多肽的癌症的肽疫苗 HK1171024A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85257506P 2006-10-17 2006-10-17

Publications (1)

Publication Number Publication Date
HK1171024A1 true HK1171024A1 (zh) 2013-03-15

Family

ID=39313729

Family Applications (4)

Application Number Title Priority Date Filing Date
HK09110942.9A HK1131169A1 (en) 2006-10-17 2009-11-23 Peptide vaccines for cancers expressing mphosph1 or depdc1 polypeptides
HK12111316.0A HK1171026A1 (zh) 2006-10-17 2009-11-23 用於表達 多肽的癌症的肽疫苗
HK12111315.1A HK1171025A1 (zh) 2006-10-17 2009-11-23 用於表達 多肽的癌症的肽疫苗
HK12111314.2A HK1171024A1 (zh) 2006-10-17 2009-11-23 用於表達 多肽的癌症的肽疫苗

Family Applications Before (3)

Application Number Title Priority Date Filing Date
HK09110942.9A HK1131169A1 (en) 2006-10-17 2009-11-23 Peptide vaccines for cancers expressing mphosph1 or depdc1 polypeptides
HK12111316.0A HK1171026A1 (zh) 2006-10-17 2009-11-23 用於表達 多肽的癌症的肽疫苗
HK12111315.1A HK1171025A1 (zh) 2006-10-17 2009-11-23 用於表達 多肽的癌症的肽疫苗

Country Status (18)

Country Link
US (5) US8557955B2 (zh)
EP (7) EP2695895A1 (zh)
JP (2) JP5339292B2 (zh)
KR (4) KR101493773B1 (zh)
CN (5) CN102850435B (zh)
AU (1) AU2007311395B2 (zh)
BR (1) BRPI0717651A2 (zh)
CA (2) CA2915560A1 (zh)
DK (1) DK2091965T3 (zh)
ES (4) ES2545818T3 (zh)
HK (4) HK1131169A1 (zh)
IL (4) IL198186A (zh)
MX (1) MX2009004147A (zh)
PL (1) PL2091965T3 (zh)
PT (1) PT2091965E (zh)
RU (1) RU2469044C2 (zh)
SG (2) SG10201502098YA (zh)
WO (1) WO2008047473A1 (zh)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2295601A1 (en) 2005-02-10 2011-03-16 Oncotherapy Science, Inc. Method of diagnosing bladder cancer
ES2632123T3 (es) * 2007-08-20 2017-09-11 Oncotherapy Science, Inc. Péptido CDH3 y agente medicinal que comprende el mismo
JP5640263B2 (ja) * 2008-08-28 2014-12-17 オンコセラピー・サイエンス株式会社 Ｄｅｐｄｃ１ポリペプチドを使用した膀胱癌の治療または予防のための方法
BRPI1012312A2 (pt) * 2009-03-04 2017-03-21 Oncotherapy Science Inc peptídeos vangl1 e vacinas incluindo os mesmos
TW201211250A (en) * 2010-09-07 2012-03-16 Oncotherapy Science Inc VANGL1 peptides and vaccines including the same
KR102015648B1 (ko) * 2011-08-12 2019-08-28 온코세라피 사이언스 가부시키가이샤 Ｍｐｈｏｓｐｈ１ 펩티드 및 이를 포함한 백신
JP2013058294A (ja) * 2011-09-09 2013-03-28 Toshiba Corp 磁気記録媒体及び磁気記録媒体の製造方法
SG11201405578TA (en) 2012-03-09 2014-11-27 Oncotherapy Science Inc Pharmaceutical composition containing peptide
JP6041297B2 (ja) * 2012-08-24 2016-12-07 国立大学法人山口大学 犬リンパ腫の診断方法及び診断キット
BR112015022189A2 (pt) * 2013-03-13 2017-11-21 Katsura Misako microvesícula, método para produção e uso da mesma
JP6696969B2 (ja) 2014-04-16 2020-05-20 ユノ・セラピューティクス・ゲーエムベーハーＪｕｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｇｍｂｈ 細胞の集団を拡大する方法、キット、及び装置
DK3205661T3 (da) * 2014-10-07 2021-08-02 Cytlimic Inc Hsp70-afledt immunitetsinducerende peptid
EP3207936B1 (en) * 2014-11-18 2021-04-21 Shionogi & Co., Ltd. Stable peptide composition
DK3269733T3 (da) 2015-03-09 2020-07-27 Cytlimic Inc Peptid afledt af gpc3, farmaceutisk sammensætning til behandling eller forebyggelse af cancer under anvendelse deraf, immunitetsinducer og fremgangsmåde til fremstilling af antigenpræsenterende celler
RU2709015C2 (ru) 2015-04-07 2019-12-13 Ситлимик Инк. Лекарственное средство
RU2022100330A (ru) 2015-08-12 2022-01-19 Онкотерапи Сайенс, Инк. Пептид, полученный из depdc1, и содержащая его вакцина
KR20180055892A (ko) * 2015-10-08 2018-05-25 온코세라피 사이언스 가부시키가이샤 Mphosph1-유래 펩티드 및 이를 포함하는 백신
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
MA45488A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés, kits et appareil de culture de cellules
WO2017068419A2 (en) 2015-10-22 2017-04-27 Juno Therapeutics Gmbh Methods, kits, agents and apparatuses for transduction
WO2018070069A1 (ja) 2016-10-11 2018-04-19 サイトリミック株式会社 医薬
TW201831502A (zh) * 2016-11-18 2018-09-01 日商腫瘤療法 科學股份有限公司 對於ｔｈ１細胞的ｄｅｐｄｃ１抗原決定位胜肽及包含其之疫苗
TW201831503A (zh) * 2016-11-18 2018-09-01 日商腫瘤療法 科學股份有限公司 對於ｔｈ１細胞的ｍｐｈｏｓｐｈ１抗原決定位胜肽及包含其之疫苗
WO2018094569A1 (zh) * 2016-11-22 2018-05-31 深圳华大基因研究院 多肽及其应用
DK3573600T3 (da) 2017-01-25 2022-05-09 Ose Immunotherapeutics Fremgangsmåde til fremstilling af en stabil emulsion til peptidlevering
CN111032850A (zh) 2017-04-27 2020-04-17 朱诺治疗学有限公司 寡聚粒子试剂及其使用方法
JP7274223B2 (ja) * 2017-07-12 2023-05-16 ノイスコム アーゲー マイクロサテライト不安定性（ｍｓｉ）癌の予防及び治療のための共通腫瘍ネオアンチゲンをベースとした万能ワクチン
RU2760984C1 (ru) 2017-12-13 2021-12-02 Иновио Фармасьютикалз, Инк. Противораковые вакцины, направленные на lemd1, и их применение
CN109932510B (zh) * 2017-12-18 2022-07-12 天津云检医学检验所有限公司 一种宫颈癌生物标志物及其检测试剂盒
CN112142824B (zh) * 2019-06-27 2022-03-11 深圳市东贵博康生化科技有限公司 具有诱导细胞毒性t淋巴细胞能力的多肽及其应用
WO2021060343A1 (ja) * 2019-09-24 2021-04-01 オンコセラピー・サイエンス株式会社 Ｕｒｌｃ１０由来ペプチドまたはｄｅｐｄｃ１由来ペプチドを認識するヒトｔ細胞が発現するｔ細胞受容体

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
HUT68510A (en) 1991-08-26 1995-06-28 Cytel Corp Process for producing hla-restricted hapatitis b virus ctl epitopes and pharmaceutical compositions containing them
ZA926441B (en) 1991-08-26 1993-06-07 Cytel Corp HLA-restricted hepatitis B virus CTL epitopes.
AU678225B2 (en) * 1993-03-11 1997-05-22 University Of Southern California Therapeutic strategies for immunoinfective cluster virus infections
US5804566A (en) 1993-08-26 1998-09-08 The Regents Of The University Of California Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides
US5679647A (en) 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US5739118A (en) 1994-04-01 1998-04-14 Apollon, Inc. Compositions and methods for delivery of genetic material
US5736524A (en) 1994-11-14 1998-04-07 Merck & Co.,. Inc. Polynucleotide tuberculosis vaccine
US5922687A (en) 1995-05-04 1999-07-13 Board Of Trustees Of The Leland Stanford Junior University Intracellular delivery of nucleic acids using pressure
US20030198642A1 (en) 1995-08-03 2003-10-23 Johannes J. Geuze Cell derived antigen presenting vesicles
US5853719A (en) 1996-04-30 1998-12-29 Duke University Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
EP0960204A4 (en) 1996-07-26 2002-01-23 Sloan Kettering Inst Cancer METHODS AND REAGENTS FOR GENETIC IMMUNIZATION
FR2766205B1 (fr) 1997-07-16 2002-08-30 Inst Nat Sante Rech Med Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede
US7001999B1 (en) 1998-04-15 2006-02-21 Ludwig Institute For Cancer Research Tumor associated nucleic acids and uses therefor
MY139226A (en) * 1998-09-30 2009-08-28 Corixa Corp Compositions and methods for wt1 specific immunotherapy
US20050123938A1 (en) 1999-01-06 2005-06-09 Chondrogene Limited Method for the detection of osteoarthritis related gene transcripts in blood
US20040241726A1 (en) 1999-01-06 2004-12-02 Chondrogene Limited Method for the detection of allergies related gene transcripts in blood
US6291663B1 (en) 1999-03-03 2001-09-18 Board Of Trustees Of The University Of Arkansas TADG-12: a novel transmembrane serine protease overexpressed in a ovarian carcinoma
US7030215B2 (en) * 1999-03-24 2006-04-18 Sangamo Biosciences, Inc. Position dependent recognition of GNN nucleotide triplets by zinc fingers
AU5047800A (en) * 1999-05-28 2000-12-18 Ludwig Institute For Cancer Research Breast, gastric and prostate cancer associated antigens and uses therefor
ATE353366T1 (de) 2000-08-22 2007-02-15 Agensys Inc Nukleinsäure und protein, genannt 158p1d7, für die behandlung und erkennung von blasenkrebs und anderen krebsarten
WO2002031111A2 (en) 2000-10-12 2002-04-18 Hyseq, Inc. Novel nucleic acids and polypeptides
EP1455816A4 (en) 2000-10-19 2007-03-28 Epimmune Inc HLA CLASS I AND II BINDING PEPTIDES AND THEIR USE
US7919467B2 (en) 2000-12-04 2011-04-05 Immunotope, Inc. Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
WO2002046416A2 (en) * 2000-12-04 2002-06-13 Argonex Pharmaceuticals Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
US20040142325A1 (en) 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
US7078217B2 (en) * 2002-01-31 2006-07-18 Wyeth Aggrecanase molecules
AU2003222103A1 (en) 2002-03-28 2003-10-13 Idec Pharmaceuticals Corporation Novel gene targets and ligands that bind thereto for treatment and diagnosis of colon carcinomas
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US20060024692A1 (en) 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
WO2005007090A2 (en) 2003-07-03 2005-01-27 President And Fellows Of Harvard College Inhibitors of the map kinase pathway
CA2580412A1 (en) 2004-09-13 2006-03-23 Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services Compositions comprising t cell receptors and methods of use thereof
EP2295601A1 (en) 2005-02-10 2011-03-16 Oncotherapy Science, Inc. Method of diagnosing bladder cancer
JP2006302684A (ja) 2005-04-21 2006-11-02 D D K Ltd カードコネクタ
EP2298895A1 (en) 2005-07-27 2011-03-23 Oncotherapy Science, Inc. Method of diagnosing small cell lung cancer
JP5276846B2 (ja) 2005-09-13 2013-08-28 国立大学法人三重大学 Ｔ細胞レセプターをコードする核酸が挿入されてなるベクター及び該レセプターを発現する細胞
US20070099251A1 (en) 2005-10-17 2007-05-03 Institute For Systems Biology Tissue-and serum-derived glycoproteins and methods of their use
TWM336439U (en) * 2008-02-14 2008-07-11 Optivision Technology Inc Diffuser capable of light condensing
JP5640263B2 (ja) 2008-08-28 2014-12-17 オンコセラピー・サイエンス株式会社 Ｄｅｐｄｃ１ポリペプチドを使用した膀胱癌の治療または予防のための方法
KR102015648B1 (ko) 2011-08-12 2019-08-28 온코세라피 사이언스 가부시키가이샤 Ｍｐｈｏｓｐｈ１ 펩티드 및 이를 포함한 백신

Also Published As

Publication number Publication date
CA2915560A1 (en) 2008-04-24
WO2008047473A1 (en) 2008-04-24
EP2476699B1 (en) 2015-06-17
BRPI0717651A2 (pt) 2013-12-24
PL2091965T3 (pl) 2013-10-31
KR101543622B1 (ko) 2015-08-11
EP2091965B1 (en) 2013-05-15
US8557955B2 (en) 2013-10-15
DK2091965T3 (da) 2013-08-05
KR101454287B1 (ko) 2014-11-04
EP2476699A2 (en) 2012-07-18
EP2091965B9 (en) 2013-09-25
IL216713A0 (en) 2012-01-31
KR101493773B1 (ko) 2015-03-03
RU2469044C2 (ru) 2012-12-10
KR20150015042A (ko) 2015-02-09
EP2091965A1 (en) 2009-08-26
US8653234B2 (en) 2014-02-18
ES2545817T3 (es) 2015-09-16
JP5339292B2 (ja) 2013-11-13
CN102850435B (zh) 2016-02-17
EP2476697A2 (en) 2012-07-18
ES2545818T3 (es) 2015-09-16
CN102850435A (zh) 2013-01-02
EP2476697A3 (en) 2013-11-27
HK1171025A1 (zh) 2013-03-15
SG10201502098YA (en) 2015-05-28
CN102850434B (zh) 2016-04-13
CN101568550B (zh) 2012-12-26
US20120288514A1 (en) 2012-11-15
IL198186A0 (en) 2011-08-01
US20150231222A1 (en) 2015-08-20
CN102850433B (zh) 2016-03-02
CN101568550A (zh) 2009-10-28
CN102850433A (zh) 2013-01-02
US20130129759A1 (en) 2013-05-23
US8552146B2 (en) 2013-10-08
HK1171026A1 (zh) 2013-03-15
KR101527473B1 (ko) 2015-06-17
ES2545457T3 (es) 2015-09-11
KR20140057681A (ko) 2014-05-13
EP2476698A2 (en) 2012-07-18
EP2476699A3 (en) 2013-11-27
EP2476698B1 (en) 2015-06-17
MX2009004147A (es) 2009-06-15
US9545437B2 (en) 2017-01-17
EP2687541A1 (en) 2014-01-22
HK1131169A1 (en) 2010-01-15
US20100028373A1 (en) 2010-02-04
EP2476698A3 (en) 2013-11-27
EP2091965A4 (en) 2011-02-16
IL222925A0 (en) 2012-12-31
KR20090083378A (ko) 2009-08-03
PT2091965E (pt) 2013-06-11
ES2415958T3 (es) 2013-07-29
EP2695895A1 (en) 2014-02-12
US9017688B2 (en) 2015-04-28
SG175566A1 (en) 2011-11-28
CN102850434A (zh) 2013-01-02
EP2687540A1 (en) 2014-01-22
US20120282286A1 (en) 2012-11-08
JP2010506826A (ja) 2010-03-04
JP2013116115A (ja) 2013-06-13
CA2667030C (en) 2016-03-15
CA2667030A1 (en) 2008-04-24
IL216712A0 (en) 2012-01-31
RU2009118432A (ru) 2010-11-27
IL198186A (en) 2017-05-29
AU2007311395B2 (en) 2013-02-21
CN105693843A (zh) 2016-06-22
EP2476697B1 (en) 2015-06-17
KR20140104057A (ko) 2014-08-27
AU2007311395A1 (en) 2008-04-24
IL216712A (en) 2017-07-31

Similar Documents

Publication Publication Date Title
HK1171024A1 (zh) 用於表達 多肽的癌症的肽疫苗
IL221062A0 (en) Stitched polypeptides
GB0721686D0 (en) Polypeptides
IL219048A (en) Peptide compounds derived from urcl10
HK1135136A1 (en) Natriuretic polypeptides
ZA200810738B (en) Polypeptide
ZA201000283B (en) Reinigung pegylierter polypeptide
GB0723712D0 (en) Peptides
EP2123666A4 (en) PEPTIDE
GB0725201D0 (en) Peptide fusion proteins
GB0623539D0 (en) Polypeptides
GB0712302D0 (en) Chrondroitinase polypeptides
GB0703945D0 (en) Peptide
GB0809659D0 (en) Polypeptides
IL203073A0 (en) Modified growth hormone polypeptides
IL197675A0 (en) Peptides
EP2097439A4 (en) NEW PEPTIDE
GB0708529D0 (en) Peptide standards
GB0812586D0 (en) Chimaeric peptide
GB0707626D0 (en) Peptides
GB0705251D0 (en) Peptides
GB0705115D0 (en) Peptides
GB0609921D0 (en) Peptides
GB0625176D0 (en) Peptides
GB0609920D0 (en) Peptides

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20221016