HK1170733A1 - 用於治療感染性疾病的噻吨衍生物 - Google Patents

用於治療感染性疾病的噻吨衍生物

Info

Publication number
HK1170733A1
HK1170733A1 HK12111516.8A HK12111516A HK1170733A1 HK 1170733 A1 HK1170733 A1 HK 1170733A1 HK 12111516 A HK12111516 A HK 12111516A HK 1170733 A1 HK1170733 A1 HK 1170733A1
Authority
HK
Hong Kong
Prior art keywords
treatment
infectious diseases
thioxanthene derivatives
thioxanthene
derivatives
Prior art date
Application number
HK12111516.8A
Other languages
English (en)
Inventor
Birgit Kjldgaard Giwercman
Original Assignee
Bkg Pharma Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bkg Pharma Aps filed Critical Bkg Pharma Aps
Publication of HK1170733A1 publication Critical patent/HK1170733A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
    • C07D335/12—Thioxanthenes
    • C07D335/20—Thioxanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK12111516.8A 2009-04-20 2012-11-14 用於治療感染性疾病的噻吨衍生物 HK1170733A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20291809P 2009-04-20 2009-04-20
EP09158229A EP2246349A1 (en) 2009-04-20 2009-04-20 Treatment of infectious diseases
PCT/EP2010/055176 WO2010122012A1 (en) 2009-04-20 2010-04-20 Thioxanthene derivatives for the treatment of infectious diseases

Publications (1)

Publication Number Publication Date
HK1170733A1 true HK1170733A1 (zh) 2013-03-08

Family

ID=40935562

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12111516.8A HK1170733A1 (zh) 2009-04-20 2012-11-14 用於治療感染性疾病的噻吨衍生物

Country Status (16)

Country Link
US (2) US8604059B2 (zh)
EP (3) EP2246349A1 (zh)
JP (2) JP5854987B2 (zh)
CN (1) CN102459245B (zh)
AU (1) AU2010240999B2 (zh)
CA (1) CA2759364A1 (zh)
DK (1) DK2421858T3 (zh)
EA (1) EA022060B1 (zh)
ES (1) ES2484016T3 (zh)
HK (1) HK1170733A1 (zh)
HR (1) HRP20140671T1 (zh)
MX (1) MX2011011062A (zh)
NZ (1) NZ596158A (zh)
PL (1) PL2421858T3 (zh)
SI (1) SI2421858T1 (zh)
WO (1) WO2010122012A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009007235A (es) * 2007-01-05 2009-10-16 Bkg Pharma Aps "derivados de tioxanteno utiles para el tratamiento de enfermedades infecciosas.".
EP2246349A1 (en) * 2009-04-20 2010-11-03 BKG Pharma ApS Treatment of infectious diseases
CN109641889A (zh) * 2016-06-23 2019-04-16 百欧伊米克思有限公司 抗感染杂环化合物及其用途
RU2738405C1 (ru) * 2020-05-26 2020-12-11 Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" АМИД (Е)-2-АМИНО-4-ОКСО-5-(2-ОКСО-2-ФЕНИЛЭТИЛИДЕН)-1-(3-ЭТОКСИКАРБОНИЛ)-4,5,6-7-ТЕТРАГИДРОБЕНЗО[b]ТИОФЕН-2-ИЛ)4,5-ДИГИДРО-1Н-ПИРРОЛ-3-КАРБОНОВОЙ КИСЛОТЫ, ОБЛАДАЮЩИЙ ПРОТИВОМИКРОБНОЙ АКТИВНОСТЬЮ

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1033663B (de) * 1954-09-18 1958-07-10 Bayer Ag Verfahren zur Herstellung von N-Alkyl-piperidylmethyl-phenthiazinen
DE1049865B (de) * 1955-09-07 1959-02-03 Farbenfabriken Bayer Aktiengesellschaft, Leverkusen-Bayerwerk Verfahren zur Herstellung von in 3-Stellung acylierten Phenthiazinderivaten
LU39637A1 (zh) * 1960-01-13
US3449334A (en) 1967-10-26 1969-06-10 Smithkline Corp 9-(2-(2-piperidinyl)ethyl) and 9-(2-(2-pyrrolidinyl)ethyl)acridanes
AU625071B2 (en) 1988-04-20 1992-07-02 Merrell Dow Pharmaceuticals Inc. N-alkylamino derivatives of aromatic, tricyclic compounds in the treatment of drug-resistant protozoal infections
JP3037988B2 (ja) 1990-09-29 2000-05-08 キーパー株式会社 合成樹脂製蛇腹製品の射出ブロー成形方法
CN100579514C (zh) 2001-07-06 2010-01-13 生命周期药物公司 通过受控制的凝聚而制备颗粒物的方法以及提高生物利用度的方法
DE10136060A1 (de) 2001-07-25 2003-02-13 Roche Diagnostics Gmbh System zur Separation von magnetisch anziehbaren Partikeln
US7544681B2 (en) * 2001-09-27 2009-06-09 Ramot At Tel Aviv University Ltd. Conjugated psychotropic drugs and uses thereof
WO2004037997A2 (en) * 2002-10-22 2004-05-06 The Trustees Of The University Of Pennsylvania Fragments and activity of rel protein in m. tuberculosis adn other uses thereof
AU2003205543A1 (en) 2003-01-14 2004-08-10 Lifecycle Pharma A/S Dry dispersions
WO2005046694A1 (en) * 2003-11-13 2005-05-26 Københavns Universitet Thioridazine and derivatives thereof for reversing anti-microbial drug-resistance
DK1744781T3 (da) 2004-04-30 2012-10-15 Bkg Pharma Aps Behandling af infektionssygdomme
DE102006030835B3 (de) 2006-07-04 2007-10-18 Forschungszentrum Karlsruhe Gmbh Hochporöses magnetisches temporäres Festbett
WO2008027521A1 (en) * 2006-09-01 2008-03-06 Immune Control, Inc. Novel compositions and methods for treatment of diseases related to activated lymphocytes
MX2009007235A (es) 2007-01-05 2009-10-16 Bkg Pharma Aps "derivados de tioxanteno utiles para el tratamiento de enfermedades infecciosas.".
EP2246349A1 (en) * 2009-04-20 2010-11-03 BKG Pharma ApS Treatment of infectious diseases

Also Published As

Publication number Publication date
CN102459245A (zh) 2012-05-16
CN102459245B (zh) 2015-01-28
EP2421858A1 (en) 2012-02-29
EP2246349A1 (en) 2010-11-03
HRP20140671T1 (hr) 2014-10-10
EP2778166A1 (en) 2014-09-17
CA2759364A1 (en) 2010-10-28
EA201171269A1 (ru) 2012-03-30
AU2010240999B2 (en) 2012-09-20
NZ596158A (en) 2013-02-22
DK2421858T3 (en) 2014-07-14
JP2014240401A (ja) 2014-12-25
ES2484016T3 (es) 2014-08-08
US8604059B2 (en) 2013-12-10
SI2421858T1 (sl) 2014-09-30
MX2011011062A (es) 2011-11-18
EA022060B1 (ru) 2015-10-30
WO2010122012A1 (en) 2010-10-28
PL2421858T3 (pl) 2014-10-31
JP5854987B2 (ja) 2016-02-09
EP2421858B1 (en) 2014-04-30
JP2012524118A (ja) 2012-10-11
US20140066451A1 (en) 2014-03-06
US20120122880A1 (en) 2012-05-17
AU2010240999A1 (en) 2011-11-10

Similar Documents

Publication Publication Date Title
EP2432476A4 (en) METHOD FOR THE TREATMENT OR PREVENTION OF EYE DISEASES
HK1217763A1 (zh) 用於治療疾病的方法
EP2740482A4 (en) PROPHYLACTIC OR THERAPEUTIC FOR DISEASES OF THE MOUTH VALVE
EP2493479A4 (en) METHOD FOR THE TREATMENT OF VIRUS DISEASES
IL208357A0 (en) Spiro-indole derivatives for the treatment of parasitic diseases
GB0908193D0 (en) Treatment of disease state
GB0906159D0 (en) Drug combination for the treatment of proteostatic diseases
PT2539352T (pt) Composições e métodos para tratar doenças cardíacas
HK1176870A1 (zh) 疾病的治療方法
PL2529739T3 (pl) Środek terapeutyczny lub profilaktyczny na choroby dróg żółciowych
EP2544686A4 (en) COMBINED METHODS FOR THE TREATMENT OF DISEASES
EP2429558A4 (en) MEDICINE FOR GAS TREATMENT PROPHYLAXIS
IL219138A0 (en) Process for the preparation of 4-sulfinyl-pyrazole derivatives
HK1170733A1 (zh) 用於治療感染性疾病的噻吨衍生物
HK1158954A1 (en) 1-amino-alkylcyclohexane derivatives for the treatment of inflammatory skin diseases
IL220134A0 (en) Thiazole derivatives for the treatment of diseases such as cancer
GB0901727D0 (en) The treatment of ophthalmic diseases
GB0908666D0 (en) Treatment of proteostatic disease
GB0920651D0 (en) Molecular methods for the treatment of disease
GB0910944D0 (en) Respiratory disease treatment
GB0901831D0 (en) Respiratory disease treatment
GB0901832D0 (en) Respiratory disease treatment
TH0901000513A (th) อนุพันธ์สไปโรไซคลิค แอมีดสำหรับการรักษาโรคปอด
GB201009094D0 (en) Compounds for the treatment of closridium difficile-associated disease

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190425