DK2421858T3 - Thioxanthene derivatives for the treatment of infectious diseases - Google Patents
Thioxanthene derivatives for the treatment of infectious diseasesInfo
- Publication number
- DK2421858T3 DK2421858T3 DK10713994.1T DK10713994T DK2421858T3 DK 2421858 T3 DK2421858 T3 DK 2421858T3 DK 10713994 T DK10713994 T DK 10713994T DK 2421858 T3 DK2421858 T3 DK 2421858T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- infectious diseases
- thioxanthene derivatives
- thioxanthene
- derivatives
- Prior art date
Links
- 208000035473 Communicable disease Diseases 0.000 title 1
- 229940054058 antipsychotic thioxanthene derivative Drugs 0.000 title 1
- 150000005075 thioxanthenes Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
- C07D335/12—Thioxanthenes
- C07D335/20—Thioxanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20291809P | 2009-04-20 | 2009-04-20 | |
| EP09158229A EP2246349A1 (en) | 2009-04-20 | 2009-04-20 | Treatment of infectious diseases |
| PCT/EP2010/055176 WO2010122012A1 (en) | 2009-04-20 | 2010-04-20 | Thioxanthene derivatives for the treatment of infectious diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2421858T3 true DK2421858T3 (en) | 2014-07-14 |
Family
ID=40935562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10713994.1T DK2421858T3 (en) | 2009-04-20 | 2010-04-20 | Thioxanthene derivatives for the treatment of infectious diseases |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8604059B2 (da) |
| EP (3) | EP2246349A1 (da) |
| JP (2) | JP5854987B2 (da) |
| CN (1) | CN102459245B (da) |
| AU (1) | AU2010240999B2 (da) |
| CA (1) | CA2759364A1 (da) |
| DK (1) | DK2421858T3 (da) |
| EA (1) | EA022060B1 (da) |
| ES (1) | ES2484016T3 (da) |
| HK (1) | HK1170733A1 (da) |
| HR (1) | HRP20140671T1 (da) |
| MX (1) | MX2011011062A (da) |
| NZ (1) | NZ596158A (da) |
| PL (1) | PL2421858T3 (da) |
| SI (1) | SI2421858T1 (da) |
| WO (1) | WO2010122012A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008080398A1 (en) * | 2007-01-05 | 2008-07-10 | Bkg Pharma Aps | Anti - infective agents such as phenothiazine and thioxanthene derivates to treat infectious diseases |
| EP2246349A1 (en) * | 2009-04-20 | 2010-11-03 | BKG Pharma ApS | Treatment of infectious diseases |
| WO2017222466A1 (en) * | 2016-06-23 | 2017-12-28 | Bioimics Ab | Anti-infective heterocyclic compounds and uses thereof |
| RU2738405C1 (ru) * | 2020-05-26 | 2020-12-11 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" | АМИД (Е)-2-АМИНО-4-ОКСО-5-(2-ОКСО-2-ФЕНИЛЭТИЛИДЕН)-1-(3-ЭТОКСИКАРБОНИЛ)-4,5,6-7-ТЕТРАГИДРОБЕНЗО[b]ТИОФЕН-2-ИЛ)4,5-ДИГИДРО-1Н-ПИРРОЛ-3-КАРБОНОВОЙ КИСЛОТЫ, ОБЛАДАЮЩИЙ ПРОТИВОМИКРОБНОЙ АКТИВНОСТЬЮ |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1033663B (de) * | 1954-09-18 | 1958-07-10 | Bayer Ag | Verfahren zur Herstellung von N-Alkyl-piperidylmethyl-phenthiazinen |
| BE550647A (da) * | 1955-09-07 | |||
| NL258554A (da) * | 1960-01-13 | |||
| US3449334A (en) | 1967-10-26 | 1969-06-10 | Smithkline Corp | 9-(2-(2-piperidinyl)ethyl) and 9-(2-(2-pyrrolidinyl)ethyl)acridanes |
| NZ228748A (en) | 1988-04-20 | 1991-07-26 | Merrell Dow Pharma | Treating drug-resistant protozoal infections with a tricyclic compound and an antiprotozoal agent: composition and kit therefor |
| JP3037988B2 (ja) | 1990-09-29 | 2000-05-08 | キーパー株式会社 | 合成樹脂製蛇腹製品の射出ブロー成形方法 |
| BR0210867A (pt) | 2001-07-06 | 2004-06-29 | Lifecycle Pharma As | Processo para a preparação de um material particulado, métodos para aglomeração controlada de um material sólido finamente disperso, para melhorar a biodisponibilidade de uma substância terapêutica e/ou profilaticamente ativa, e para melhorar a vida em prateleira de uma composição farmacêutica, material articulado, composição farmacêutica, uso de um veìculo, material particulado farmacêutico, e, uso de aluminossilicato de magnésio e/ou de aluminometassilicato de magnésio |
| DE10136060A1 (de) | 2001-07-25 | 2003-02-13 | Roche Diagnostics Gmbh | System zur Separation von magnetisch anziehbaren Partikeln |
| US7544681B2 (en) * | 2001-09-27 | 2009-06-09 | Ramot At Tel Aviv University Ltd. | Conjugated psychotropic drugs and uses thereof |
| WO2004037997A2 (en) * | 2002-10-22 | 2004-05-06 | The Trustees Of The University Of Pennsylvania | Fragments and activity of rel protein in m. tuberculosis adn other uses thereof |
| AU2003205543A1 (en) | 2003-01-14 | 2004-08-10 | Lifecycle Pharma A/S | Dry dispersions |
| ES2377016T3 (es) * | 2003-11-13 | 2012-03-21 | Noa Sic Aps | Tioridazina y derivados de la misma para invertir la resistencia a los fármacos anti-microbianos |
| MXPA06012566A (es) * | 2004-04-30 | 2007-05-09 | Bkg Pharma Aps | Tratamiento de enfermedades infecciosas. |
| DE102006030835B3 (de) | 2006-07-04 | 2007-10-18 | Forschungszentrum Karlsruhe Gmbh | Hochporöses magnetisches temporäres Festbett |
| JP2010502621A (ja) * | 2006-09-01 | 2010-01-28 | イミユーン・コントロール・インコーポレーテツド | リンパ球の活性化に関連した病気を治療するための新規な組成物および方法 |
| WO2008080398A1 (en) | 2007-01-05 | 2008-07-10 | Bkg Pharma Aps | Anti - infective agents such as phenothiazine and thioxanthene derivates to treat infectious diseases |
| EP2246349A1 (en) * | 2009-04-20 | 2010-11-03 | BKG Pharma ApS | Treatment of infectious diseases |
-
2009
- 2009-04-20 EP EP09158229A patent/EP2246349A1/en not_active Withdrawn
-
2010
- 2010-04-20 AU AU2010240999A patent/AU2010240999B2/en not_active Ceased
- 2010-04-20 CA CA2759364A patent/CA2759364A1/en not_active Abandoned
- 2010-04-20 EP EP14166490.4A patent/EP2778166A1/en not_active Withdrawn
- 2010-04-20 WO PCT/EP2010/055176 patent/WO2010122012A1/en active Application Filing
- 2010-04-20 US US13/265,149 patent/US8604059B2/en not_active Expired - Fee Related
- 2010-04-20 MX MX2011011062A patent/MX2011011062A/es active IP Right Grant
- 2010-04-20 ES ES10713994.1T patent/ES2484016T3/es active Active
- 2010-04-20 CN CN201080027053.2A patent/CN102459245B/zh not_active Expired - Fee Related
- 2010-04-20 EP EP10713994.1A patent/EP2421858B1/en not_active Not-in-force
- 2010-04-20 JP JP2012506464A patent/JP5854987B2/ja not_active Expired - Fee Related
- 2010-04-20 PL PL10713994T patent/PL2421858T3/pl unknown
- 2010-04-20 EA EA201171269A patent/EA022060B1/ru not_active IP Right Cessation
- 2010-04-20 NZ NZ596158A patent/NZ596158A/xx not_active IP Right Cessation
- 2010-04-20 SI SI201030678T patent/SI2421858T1/sl unknown
- 2010-04-20 DK DK10713994.1T patent/DK2421858T3/da active
-
2012
- 2012-11-14 HK HK12111516.8A patent/HK1170733A1/xx not_active IP Right Cessation
-
2013
- 2013-11-04 US US14/071,260 patent/US20140066451A1/en not_active Abandoned
-
2014
- 2014-07-14 HR HRP20140671AT patent/HRP20140671T1/hr unknown
- 2014-07-25 JP JP2014152272A patent/JP2014240401A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP2421858A1 (en) | 2012-02-29 |
| JP2012524118A (ja) | 2012-10-11 |
| ES2484016T3 (es) | 2014-08-08 |
| EP2246349A1 (en) | 2010-11-03 |
| NZ596158A (en) | 2013-02-22 |
| US8604059B2 (en) | 2013-12-10 |
| JP5854987B2 (ja) | 2016-02-09 |
| US20120122880A1 (en) | 2012-05-17 |
| EA201171269A1 (ru) | 2012-03-30 |
| EA022060B1 (ru) | 2015-10-30 |
| WO2010122012A1 (en) | 2010-10-28 |
| EP2421858B1 (en) | 2014-04-30 |
| CN102459245B (zh) | 2015-01-28 |
| HK1170733A1 (en) | 2013-03-08 |
| JP2014240401A (ja) | 2014-12-25 |
| SI2421858T1 (sl) | 2014-09-30 |
| PL2421858T3 (pl) | 2014-10-31 |
| AU2010240999A1 (en) | 2011-11-10 |
| EP2778166A1 (en) | 2014-09-17 |
| CN102459245A (zh) | 2012-05-16 |
| US20140066451A1 (en) | 2014-03-06 |
| AU2010240999B2 (en) | 2012-09-20 |
| HRP20140671T1 (hr) | 2014-10-10 |
| CA2759364A1 (en) | 2010-10-28 |
| MX2011011062A (es) | 2011-11-18 |
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