HK1170733A1 - Thioxanthene derivatives for the treatment of infectious diseases - Google Patents

Thioxanthene derivatives for the treatment of infectious diseases

Info

Publication number
HK1170733A1
HK1170733A1 HK12111516.8A HK12111516A HK1170733A1 HK 1170733 A1 HK1170733 A1 HK 1170733A1 HK 12111516 A HK12111516 A HK 12111516A HK 1170733 A1 HK1170733 A1 HK 1170733A1
Authority
HK
Hong Kong
Prior art keywords
treatment
infectious diseases
thioxanthene derivatives
thioxanthene
derivatives
Prior art date
Application number
HK12111516.8A
Other languages
English (en)
Chinese (zh)
Inventor
Birgit Kjldgaard Giwercman
Original Assignee
Bkg Pharma Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bkg Pharma Aps filed Critical Bkg Pharma Aps
Publication of HK1170733A1 publication Critical patent/HK1170733A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/10Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
    • C07D335/12Thioxanthenes
    • C07D335/20Thioxanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK12111516.8A 2009-04-20 2012-11-14 Thioxanthene derivatives for the treatment of infectious diseases HK1170733A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20291809P 2009-04-20 2009-04-20
EP09158229A EP2246349A1 (en) 2009-04-20 2009-04-20 Treatment of infectious diseases
PCT/EP2010/055176 WO2010122012A1 (en) 2009-04-20 2010-04-20 Thioxanthene derivatives for the treatment of infectious diseases

Publications (1)

Publication Number Publication Date
HK1170733A1 true HK1170733A1 (en) 2013-03-08

Family

ID=40935562

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12111516.8A HK1170733A1 (en) 2009-04-20 2012-11-14 Thioxanthene derivatives for the treatment of infectious diseases

Country Status (16)

Country Link
US (2) US8604059B2 (da)
EP (3) EP2246349A1 (da)
JP (2) JP5854987B2 (da)
CN (1) CN102459245B (da)
AU (1) AU2010240999B2 (da)
CA (1) CA2759364A1 (da)
DK (1) DK2421858T3 (da)
EA (1) EA022060B1 (da)
ES (1) ES2484016T3 (da)
HK (1) HK1170733A1 (da)
HR (1) HRP20140671T1 (da)
MX (1) MX2011011062A (da)
NZ (1) NZ596158A (da)
PL (1) PL2421858T3 (da)
SI (1) SI2421858T1 (da)
WO (1) WO2010122012A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008080398A1 (en) * 2007-01-05 2008-07-10 Bkg Pharma Aps Anti - infective agents such as phenothiazine and thioxanthene derivates to treat infectious diseases
EP2246349A1 (en) * 2009-04-20 2010-11-03 BKG Pharma ApS Treatment of infectious diseases
AU2017279905B2 (en) * 2016-06-23 2021-10-14 Bioimics Ab Anti-infective heterocyclic compounds and uses thereof
RU2738405C1 (ru) * 2020-05-26 2020-12-11 Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" АМИД (Е)-2-АМИНО-4-ОКСО-5-(2-ОКСО-2-ФЕНИЛЭТИЛИДЕН)-1-(3-ЭТОКСИКАРБОНИЛ)-4,5,6-7-ТЕТРАГИДРОБЕНЗО[b]ТИОФЕН-2-ИЛ)4,5-ДИГИДРО-1Н-ПИРРОЛ-3-КАРБОНОВОЙ КИСЛОТЫ, ОБЛАДАЮЩИЙ ПРОТИВОМИКРОБНОЙ АКТИВНОСТЬЮ

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1033663B (de) * 1954-09-18 1958-07-10 Bayer Ag Verfahren zur Herstellung von N-Alkyl-piperidylmethyl-phenthiazinen
DE1049865B (de) * 1955-09-07 1959-02-03 Farbenfabriken Bayer Aktiengesellschaft, Leverkusen-Bayerwerk Verfahren zur Herstellung von in 3-Stellung acylierten Phenthiazinderivaten
NL258554A (da) 1960-01-13
US3449334A (en) 1967-10-26 1969-06-10 Smithkline Corp 9-(2-(2-piperidinyl)ethyl) and 9-(2-(2-pyrrolidinyl)ethyl)acridanes
AU625071B2 (en) 1988-04-20 1992-07-02 Merrell Dow Pharmaceuticals Inc. N-alkylamino derivatives of aromatic, tricyclic compounds in the treatment of drug-resistant protozoal infections
JP3037988B2 (ja) 1990-09-29 2000-05-08 キーパー株式会社 合成樹脂製蛇腹製品の射出ブロー成形方法
ES2739023T3 (es) 2001-07-06 2020-01-28 Veloxis Pharmaceuticals As Aglomeración controlada
DE10136060A1 (de) 2001-07-25 2003-02-13 Roche Diagnostics Gmbh System zur Separation von magnetisch anziehbaren Partikeln
US7544681B2 (en) * 2001-09-27 2009-06-09 Ramot At Tel Aviv University Ltd. Conjugated psychotropic drugs and uses thereof
WO2004037192A2 (en) * 2002-10-22 2004-05-06 The Trustees Of The University Of Pennsylvania Identification of antimycobacterial targets and the inhibition thereof as a treatment for infectious diseases
WO2004062643A1 (en) 2003-01-14 2004-07-29 Lifecycle Pharma A/S Dry dispersions
DK1689405T3 (da) * 2003-11-13 2012-02-20 Noa Sic Aps Thioridazin og derivater deraf til reversering af anti-mikrobiel resistens
US20080318970A1 (en) * 2004-04-30 2008-12-25 Birgit Kjaeldgaard Giwercman Treatment of Infectious Diseases
DE102006030835B3 (de) 2006-07-04 2007-10-18 Forschungszentrum Karlsruhe Gmbh Hochporöses magnetisches temporäres Festbett
WO2008027521A1 (en) * 2006-09-01 2008-03-06 Immune Control, Inc. Novel compositions and methods for treatment of diseases related to activated lymphocytes
WO2008080398A1 (en) 2007-01-05 2008-07-10 Bkg Pharma Aps Anti - infective agents such as phenothiazine and thioxanthene derivates to treat infectious diseases
EP2246349A1 (en) * 2009-04-20 2010-11-03 BKG Pharma ApS Treatment of infectious diseases

Also Published As

Publication number Publication date
HRP20140671T1 (hr) 2014-10-10
EA201171269A1 (ru) 2012-03-30
JP2014240401A (ja) 2014-12-25
EA022060B1 (ru) 2015-10-30
JP5854987B2 (ja) 2016-02-09
PL2421858T3 (pl) 2014-10-31
WO2010122012A1 (en) 2010-10-28
ES2484016T3 (es) 2014-08-08
EP2421858B1 (en) 2014-04-30
MX2011011062A (es) 2011-11-18
US8604059B2 (en) 2013-12-10
EP2778166A1 (en) 2014-09-17
US20120122880A1 (en) 2012-05-17
CA2759364A1 (en) 2010-10-28
JP2012524118A (ja) 2012-10-11
DK2421858T3 (en) 2014-07-14
AU2010240999A1 (en) 2011-11-10
AU2010240999B2 (en) 2012-09-20
CN102459245B (zh) 2015-01-28
CN102459245A (zh) 2012-05-16
EP2246349A1 (en) 2010-11-03
EP2421858A1 (en) 2012-02-29
NZ596158A (en) 2013-02-22
US20140066451A1 (en) 2014-03-06
SI2421858T1 (sl) 2014-09-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190425