PT2539352T - Composições e métodos para tratar doenças cardíacas - Google Patents

Composições e métodos para tratar doenças cardíacas

Info

Publication number
PT2539352T
PT2539352T PT117133959T PT11713395T PT2539352T PT 2539352 T PT2539352 T PT 2539352T PT 117133959 T PT117133959 T PT 117133959T PT 11713395 T PT11713395 T PT 11713395T PT 2539352 T PT2539352 T PT 2539352T
Authority
PT
Portugal
Prior art keywords
treating cardiac
cardiac diseases
amp derivatives
derivatives
diseases
Prior art date
Application number
PT117133959T
Other languages
English (en)
Inventor
liang Bruce
A Jacobson Kenneth
V Joshi Bhalchandra
Santosh Kumar Thatikonda
Original Assignee
Univ Connecticut
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Connecticut, Us Health filed Critical Univ Connecticut
Publication of PT2539352T publication Critical patent/PT2539352T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT117133959T 2010-02-22 2011-02-22 Composições e métodos para tratar doenças cardíacas PT2539352T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30668710P 2010-02-22 2010-02-22

Publications (1)

Publication Number Publication Date
PT2539352T true PT2539352T (pt) 2018-01-03

Family

ID=44212109

Family Applications (1)

Application Number Title Priority Date Filing Date
PT117133959T PT2539352T (pt) 2010-02-22 2011-02-22 Composições e métodos para tratar doenças cardíacas

Country Status (11)

Country Link
US (3) US8822434B2 (pt)
EP (1) EP2539352B1 (pt)
CN (1) CN102985432B (pt)
AU (1) AU2011217815B2 (pt)
CA (1) CA2789259C (pt)
DK (1) DK2539352T3 (pt)
ES (1) ES2654363T3 (pt)
HU (1) HUE037611T2 (pt)
PL (1) PL2539352T3 (pt)
PT (1) PT2539352T (pt)
WO (1) WO2011103552A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2539352B1 (en) 2010-02-22 2017-10-04 University of Connecticut Amp derivatives for treating cardiac diseases
DE112017000558T5 (de) 2016-01-29 2018-11-08 Semiconductor Energy Laboratory Co., Ltd. Licht emittierendes Element, Licht emittierende Vorrichtung, elektronisches Gerät und Beleuchtungsvorrichtung
EP3445368A4 (en) 2016-04-21 2019-12-18 Astrocyte Pharmaceuticals, Inc. COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS
CN109689636A (zh) 2016-09-14 2019-04-26 株式会社半导体能源研究所 有机化合物、发光元件、发光装置、电子设备及照明装置
KR20180077029A (ko) 2016-12-28 2018-07-06 가부시키가이샤 한도오따이 에네루기 켄큐쇼 유기 화합물, 발광 소자, 발광 장치, 전자 기기, 표시 장치, 및 조명 장치
WO2018203171A1 (en) 2017-05-02 2018-11-08 Semiconductor Energy Laboratory Co., Ltd. Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device
JP7311855B2 (ja) 2018-02-09 2023-07-20 アストロサイト ファーマシューティカルズ， インコーポレイテッド 嗜癖および関連する障害を処置するための化合物および方法
WO2019229591A1 (ja) 2018-05-31 2019-12-05 株式会社半導体エネルギー研究所 有機化合物、発光素子、発光装置、電子機器、および照明装置
EP3856741A4 (en) 2018-09-26 2022-06-22 Astrocyte Pharmaceuticals, Inc. POLYMORPHOUS COMPOUNDS AND USES THEREOF

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712258A (en) * 1995-03-23 1998-01-27 The Trustees Of The University Of Pennsylvania Inotropic ADP and ATP analogues and their pharmaceutical compositions
US7348315B2 (en) * 1995-03-23 2008-03-25 The University Of Connecticut Methods of treating heart failure with modified ATP, ADP and AMP compounds
US6329349B1 (en) * 1997-10-23 2001-12-11 Trustees Of The University Of Pennsylvania Methods for reducing ischemic injury of the heart via the sequential administration of monophosphoryl lipid A and adenosine receptor agents
US6677356B1 (en) * 1999-08-24 2004-01-13 Medicure International Inc. Treatment of cardiovascular and related pathologies
US6586413B2 (en) * 1999-11-05 2003-07-01 The United States Of America As Represented By The Department Of Health And Human Services Methods and compositions for reducing ischemic injury of the heart by administering adenosine receptor agonists and antagonists
EP1252160B1 (en) 2000-01-14 2006-08-16 The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services Methanocarba cycloalkyl nucleoside analogues
CA2601996A1 (en) 2004-09-09 2006-03-23 Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services Purine derivatives as a3 and a1 adenosine receptor agonists
WO2006091905A1 (en) 2005-02-25 2006-08-31 Gilead Sciences, Inc. Bicyclo (3.1.0) hexane derivatives as antiviral compounds
PL2049127T3 (pl) * 2006-05-23 2015-03-31 Univ Connecticut N-metanokarbapochodne do leczenia chorób serca
EP2539352B1 (en) 2010-02-22 2017-10-04 University of Connecticut Amp derivatives for treating cardiac diseases

Also Published As

Publication number Publication date
WO2011103552A3 (en) 2012-03-15
CN102985432A (zh) 2013-03-20
AU2011217815A1 (en) 2012-10-11
DK2539352T3 (en) 2018-01-08
CN102985432B (zh) 2016-11-02
US20160166591A1 (en) 2016-06-16
US8822434B2 (en) 2014-09-02
HUE037611T2 (hu) 2018-09-28
US20150038463A1 (en) 2015-02-05
PL2539352T3 (pl) 2018-03-30
WO2011103552A9 (en) 2012-04-26
EP2539352A2 (en) 2013-01-02
US9526739B2 (en) 2016-12-27
AU2011217815B2 (en) 2015-03-12
US20110212924A1 (en) 2011-09-01
WO2011103552A2 (en) 2011-08-25
CA2789259C (en) 2019-08-20
ES2654363T3 (es) 2018-02-13
CA2789259A1 (en) 2011-08-25
US9303053B2 (en) 2016-04-05
EP2539352B1 (en) 2017-10-04

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