PL2539352T3 - Pochodne amp do leczenia chorób serca - Google Patents

Pochodne amp do leczenia chorób serca

Info

Publication number
PL2539352T3
PL2539352T3 PL11713395T PL11713395T PL2539352T3 PL 2539352 T3 PL2539352 T3 PL 2539352T3 PL 11713395 T PL11713395 T PL 11713395T PL 11713395 T PL11713395 T PL 11713395T PL 2539352 T3 PL2539352 T3 PL 2539352T3
Authority
PL
Poland
Prior art keywords
treating cardiac
cardiac diseases
amp derivatives
derivatives
diseases
Prior art date
Application number
PL11713395T
Other languages
English (en)
Inventor
Bruce Liang
Kenneth A. Jacobson
Bhalchandra V. Joshi
Thatikonda Santosh Kumar
Original Assignee
University Of Connecticut
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Connecticut, The United States Of America, As Represented By The Secretary, Department Of Health And Human Services filed Critical University Of Connecticut
Publication of PL2539352T3 publication Critical patent/PL2539352T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL11713395T 2010-02-22 2011-02-22 Pochodne amp do leczenia chorób serca PL2539352T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30668710P 2010-02-22 2010-02-22
EP11713395.9A EP2539352B1 (en) 2010-02-22 2011-02-22 Amp derivatives for treating cardiac diseases
PCT/US2011/025680 WO2011103552A2 (en) 2010-02-22 2011-02-22 Compositions and methods to treat cardiac diseases

Publications (1)

Publication Number Publication Date
PL2539352T3 true PL2539352T3 (pl) 2018-03-30

Family

ID=44212109

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11713395T PL2539352T3 (pl) 2010-02-22 2011-02-22 Pochodne amp do leczenia chorób serca

Country Status (11)

Country Link
US (3) US8822434B2 (pl)
EP (1) EP2539352B1 (pl)
CN (1) CN102985432B (pl)
AU (1) AU2011217815B2 (pl)
CA (1) CA2789259C (pl)
DK (1) DK2539352T3 (pl)
ES (1) ES2654363T3 (pl)
HU (1) HUE037611T2 (pl)
PL (1) PL2539352T3 (pl)
PT (1) PT2539352T (pl)
WO (1) WO2011103552A2 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2539352T (pt) 2010-02-22 2018-01-03 Univ Connecticut Composições e métodos para tratar doenças cardíacas
KR102270584B1 (ko) 2016-01-29 2021-06-28 가부시키가이샤 한도오따이 에네루기 켄큐쇼 발광 소자, 발광 장치, 전자 기기, 및 조명 장치
CN109310695B (zh) 2016-04-21 2022-04-01 阿斯特罗赛特制药公司 治疗神经和心血管病况的化合物和方法
TWI856504B (zh) 2016-09-14 2024-09-21 日商半導體能源研究所股份有限公司 有機化合物、發光元件、發光裝置、電子裝置及照明設備
KR102701648B1 (ko) 2016-12-28 2024-09-03 가부시키가이샤 한도오따이 에네루기 켄큐쇼 유기 화합물, 발광 소자, 발광 장치, 전자 기기, 표시 장치, 및 조명 장치
US11555030B2 (en) 2017-05-02 2023-01-17 Semiconductor Energy Laboratory Co., Ltd. Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device
US11839615B2 (en) 2018-02-09 2023-12-12 Astrocyte Pharmaceuticals, Inc. Compounds and methods for treating addiction and related disorders
CN112204002A (zh) 2018-05-31 2021-01-08 株式会社半导体能源研究所 有机化合物、发光元件、发光装置、电子设备及照明装置
US12089490B2 (en) 2018-07-31 2024-09-10 Semiconductor Energy Laboratory Co., Ltd. Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device
EP3856741A4 (en) 2018-09-26 2022-06-22 Astrocyte Pharmaceuticals, Inc. POLYMORPHOUS COMPOUNDS AND USES THEREOF
CN116173046B (zh) * 2023-03-29 2025-03-18 南京医科大学 一种天然小分子Peli1抑制剂
JP2026524988A (ja) * 2023-07-21 2026-07-24 コーノヴァス・ファーマシューティカルズ・インコーポレイテッド 心臓のp2x受容体アゴニストの水性製剤及びその疾患の治療における使用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712258A (en) 1995-03-23 1998-01-27 The Trustees Of The University Of Pennsylvania Inotropic ADP and ATP analogues and their pharmaceutical compositions
US7348315B2 (en) 1995-03-23 2008-03-25 The University Of Connecticut Methods of treating heart failure with modified ATP, ADP and AMP compounds
AU1363699A (en) 1997-10-23 1999-05-10 National Institute Of Health Methods for reducing ischemic injury of the heart via the sequential administ ration of monophosphoryl lipid a and adenosine receptor agents
WO2001013900A2 (en) 1999-08-24 2001-03-01 Medicure International Inc. Compositions for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds
US6586413B2 (en) 1999-11-05 2003-07-01 The United States Of America As Represented By The Department Of Health And Human Services Methods and compositions for reducing ischemic injury of the heart by administering adenosine receptor agonists and antagonists
ATE336492T1 (de) 2000-01-14 2006-09-15 Us Gov Health & Human Serv Methonocarbacycloalkylanaloga von nucleosiden
KR20070050484A (ko) 2004-09-09 2007-05-15 더 가브먼트 오브 더 유나이티드 스테이츠 오브 아메리카, 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 A1 및 a3 아데노신 수용체 아고니스트로서의 퓨린 유도체
WO2006091905A1 (en) 2005-02-25 2006-08-31 Gilead Sciences, Inc. Bicyclo (3.1.0) hexane derivatives as antiviral compounds
ES2526713T3 (es) 2006-05-23 2015-01-14 University Of Connecticut Derivados de N-metanocarba para tratar enfermedades cardiacas
PT2539352T (pt) 2010-02-22 2018-01-03 Univ Connecticut Composições e métodos para tratar doenças cardíacas

Also Published As

Publication number Publication date
US20110212924A1 (en) 2011-09-01
WO2011103552A9 (en) 2012-04-26
AU2011217815B2 (en) 2015-03-12
ES2654363T3 (es) 2018-02-13
EP2539352A2 (en) 2013-01-02
CA2789259C (en) 2019-08-20
CA2789259A1 (en) 2011-08-25
US9526739B2 (en) 2016-12-27
HUE037611T2 (hu) 2018-09-28
WO2011103552A2 (en) 2011-08-25
US9303053B2 (en) 2016-04-05
US20150038463A1 (en) 2015-02-05
WO2011103552A3 (en) 2012-03-15
US8822434B2 (en) 2014-09-02
PT2539352T (pt) 2018-01-03
AU2011217815A1 (en) 2012-10-11
CN102985432B (zh) 2016-11-02
CN102985432A (zh) 2013-03-20
DK2539352T3 (en) 2018-01-08
EP2539352B1 (en) 2017-10-04
US20160166591A1 (en) 2016-06-16

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