PL2539352T3 - Pochodne amp do leczenia chorób serca - Google Patents

Pochodne amp do leczenia chorób serca

Info

Publication number
PL2539352T3
PL2539352T3 PL11713395T PL11713395T PL2539352T3 PL 2539352 T3 PL2539352 T3 PL 2539352T3 PL 11713395 T PL11713395 T PL 11713395T PL 11713395 T PL11713395 T PL 11713395T PL 2539352 T3 PL2539352 T3 PL 2539352T3
Authority
PL
Poland
Prior art keywords
treating cardiac
cardiac diseases
amp derivatives
derivatives
diseases
Prior art date
Application number
PL11713395T
Other languages
English (en)
Inventor
Bruce Liang
Kenneth A. Jacobson
Bhalchandra V. Joshi
Thatikonda Santosh Kumar
Original Assignee
University Of Connecticut
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Connecticut, The United States Of America, As Represented By The Secretary, Department Of Health And Human Services filed Critical University Of Connecticut
Publication of PL2539352T3 publication Critical patent/PL2539352T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL11713395T 2010-02-22 2011-02-22 Pochodne amp do leczenia chorób serca PL2539352T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30668710P 2010-02-22 2010-02-22
PCT/US2011/025680 WO2011103552A2 (en) 2010-02-22 2011-02-22 Compositions and methods to treat cardiac diseases
EP11713395.9A EP2539352B1 (en) 2010-02-22 2011-02-22 Amp derivatives for treating cardiac diseases

Publications (1)

Publication Number Publication Date
PL2539352T3 true PL2539352T3 (pl) 2018-03-30

Family

ID=44212109

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11713395T PL2539352T3 (pl) 2010-02-22 2011-02-22 Pochodne amp do leczenia chorób serca

Country Status (11)

Country Link
US (3) US8822434B2 (pl)
EP (1) EP2539352B1 (pl)
CN (1) CN102985432B (pl)
AU (1) AU2011217815B2 (pl)
CA (1) CA2789259C (pl)
DK (1) DK2539352T3 (pl)
ES (1) ES2654363T3 (pl)
HU (1) HUE037611T2 (pl)
PL (1) PL2539352T3 (pl)
PT (1) PT2539352T (pl)
WO (1) WO2011103552A2 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2539352B1 (en) 2010-02-22 2017-10-04 University of Connecticut Amp derivatives for treating cardiac diseases
DE112017000558B4 (de) 2016-01-29 2025-04-30 Semiconductor Energy Laboratory Co., Ltd. Lochtransportmaterial, organische Verbindung, Licht emittierendes Element und Licht emittierende Vorrichtung
MX391725B (es) 2016-04-21 2025-03-21 Astrocyte Pharmaceuticals Inc Compuestos y metodos para tratamiento de afecciones neurologicas y cardiovasculares.
KR20250012189A (ko) 2016-09-14 2025-01-23 가부시키가이샤 한도오따이 에네루기 켄큐쇼 유기 화합물, 발광 소자, 발광 장치, 전자 기기, 및 조명 장치
KR102701648B1 (ko) 2016-12-28 2024-09-03 가부시키가이샤 한도오따이 에네루기 켄큐쇼 유기 화합물, 발광 소자, 발광 장치, 전자 기기, 표시 장치, 및 조명 장치
KR102581109B1 (ko) 2017-05-02 2023-09-21 가부시키가이샤 한도오따이 에네루기 켄큐쇼 유기 화합물, 발광 소자, 발광 장치, 전자 기기, 및 조명 장치
KR102791276B1 (ko) 2018-02-09 2025-04-08 아스트로사이트 파마슈티컬스, 인코포레이티드 중독 및 관련 장애를 치료하기 위한 화합물 및 방법
WO2019229591A1 (ja) 2018-05-31 2019-12-05 株式会社半導体エネルギー研究所 有機化合物、発光素子、発光装置、電子機器、および照明装置
JP7450539B2 (ja) 2018-07-31 2024-03-15 株式会社半導体エネルギー研究所 有機化合物および発光素子
EA202190576A1 (ru) 2018-09-26 2021-09-03 Астросайт Фармасьютикалс, Инк. Полиморфные соединения и их применение
CN116173046B (zh) * 2023-03-29 2025-03-18 南京医科大学 一种天然小分子Peli1抑制剂
US20250049710A1 (en) * 2023-07-21 2025-02-13 Comovus Pharmaceuticals, Inc. Aqueous formulations of a cardiac p2x receptor agonist and their use in treating medical disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712258A (en) 1995-03-23 1998-01-27 The Trustees Of The University Of Pennsylvania Inotropic ADP and ATP analogues and their pharmaceutical compositions
US7348315B2 (en) 1995-03-23 2008-03-25 The University Of Connecticut Methods of treating heart failure with modified ATP, ADP and AMP compounds
WO1999020284A1 (en) 1997-10-23 1999-04-29 Trustees Of The University Of Pennsylvania Methods for reducing ischemic injury of the heart via the sequential administration of monophosphoryl lipid a and adenosine receptor agents
WO2001013900A2 (en) 1999-08-24 2001-03-01 Medicure International Inc. Compositions for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds
US6586413B2 (en) 1999-11-05 2003-07-01 The United States Of America As Represented By The Department Of Health And Human Services Methods and compositions for reducing ischemic injury of the heart by administering adenosine receptor agonists and antagonists
EP1252160B1 (en) 2000-01-14 2006-08-16 The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services Methanocarba cycloalkyl nucleoside analogues
JP2008512457A (ja) 2004-09-09 2008-04-24 アメリカ合衆国 A3及びa1アデノシン受容体作用薬としてのプリン誘導体
WO2006091905A1 (en) 2005-02-25 2006-08-31 Gilead Sciences, Inc. Bicyclo (3.1.0) hexane derivatives as antiviral compounds
PT2049127E (pt) 2006-05-23 2014-12-23 Univ Connecticut Derivados n-metanocarba para tratamento de doenças cardíacas
EP2539352B1 (en) 2010-02-22 2017-10-04 University of Connecticut Amp derivatives for treating cardiac diseases

Also Published As

Publication number Publication date
CA2789259C (en) 2019-08-20
CN102985432B (zh) 2016-11-02
EP2539352B1 (en) 2017-10-04
US9303053B2 (en) 2016-04-05
US9526739B2 (en) 2016-12-27
CN102985432A (zh) 2013-03-20
AU2011217815B2 (en) 2015-03-12
CA2789259A1 (en) 2011-08-25
WO2011103552A2 (en) 2011-08-25
US8822434B2 (en) 2014-09-02
HUE037611T2 (hu) 2018-09-28
PT2539352T (pt) 2018-01-03
EP2539352A2 (en) 2013-01-02
DK2539352T3 (en) 2018-01-08
AU2011217815A1 (en) 2012-10-11
WO2011103552A3 (en) 2012-03-15
US20160166591A1 (en) 2016-06-16
ES2654363T3 (es) 2018-02-13
US20150038463A1 (en) 2015-02-05
WO2011103552A9 (en) 2012-04-26
US20110212924A1 (en) 2011-09-01

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