HK1169656A1 - Substituted n-phenyl-1-(4-pyridinyl)-1h-pyrazol-3-amines n--1-(4-)-1h--3- - Google Patents

Substituted n-phenyl-1-(4-pyridinyl)-1h-pyrazol-3-amines n--1-(4-)-1h--3-

Info

Publication number
HK1169656A1
HK1169656A1 HK12110507.1A HK12110507A HK1169656A1 HK 1169656 A1 HK1169656 A1 HK 1169656A1 HK 12110507 A HK12110507 A HK 12110507A HK 1169656 A1 HK1169656 A1 HK 1169656A1
Authority
HK
Hong Kong
Prior art keywords
pyrazol
pyridinyl
amines
phenyl
substituted
Prior art date
Application number
HK12110507.1A
Other languages
English (en)
Chinese (zh)
Inventor
Gregor James Macdonald
Johannes Wilhelmus John F Thuring
Keybus Frans Alfons Maria Van Den
Yves Emiel Maria Van Roosbroeck
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1169656A1 publication Critical patent/HK1169656A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK12110507.1A 2009-09-17 2012-10-22 Substituted n-phenyl-1-(4-pyridinyl)-1h-pyrazol-3-amines n--1-(4-)-1h--3- HK1169656A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09170525 2009-09-17
PCT/EP2010/063609 WO2011033018A1 (en) 2009-09-17 2010-09-16 Substituted n-phenyl-1-(4-pyridinyl)-1h-pyrazol-3-amines

Publications (1)

Publication Number Publication Date
HK1169656A1 true HK1169656A1 (en) 2013-02-01

Family

ID=41466623

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12110507.1A HK1169656A1 (en) 2009-09-17 2012-10-22 Substituted n-phenyl-1-(4-pyridinyl)-1h-pyrazol-3-amines n--1-(4-)-1h--3-

Country Status (12)

Country Link
US (1) US8791144B2 (xx)
EP (1) EP2491024B1 (xx)
JP (1) JP5636428B2 (xx)
KR (1) KR101710197B1 (xx)
CN (1) CN102574832B (xx)
AU (1) AU2010297263B2 (xx)
BR (1) BR112012005960A2 (xx)
CA (1) CA2770932C (xx)
EA (1) EA020564B1 (xx)
ES (1) ES2446356T3 (xx)
HK (1) HK1169656A1 (xx)
WO (1) WO2011033018A1 (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
JO2784B1 (en) * 2007-10-18 2014-03-15 شركة جانسين فارماسوتيكا ان. في 5,3,1 - Triazole substitute derivative
ES2424023T3 (es) * 2007-10-18 2013-09-26 Janssen Pharmaceutica N.V. 1,2,4-triazoles trisustituidos
AU2009226988B2 (en) * 2008-03-19 2013-05-23 Janssen Pharmaceutica Nv Trisubstituted 1, 2, 4 -triazoles as nicotinic acetylcholine receptor modulators
BRPI0912196A2 (pt) * 2008-05-09 2015-10-06 Janssen Pharmaceutica Nv pirazóis trissubstituídos como moduladores do receptor de acetilcolina.
DK2571874T3 (en) 2010-05-17 2016-05-17 Forum Pharmaceuticals Inc A crystalline form of (R) -7-chloro-N- (quinuclidin-3-yl) benzo [b] thiophene-2-carboxamide hydrochloride monohydrate
DE102011055815A1 (de) 2011-11-29 2013-05-29 Aicuris Gmbh & Co. Kg Carboxamid-substituierte Heteroaryl-Pyrazole und ihre Verwendung
CA2872005A1 (en) 2012-05-08 2013-11-14 Forum Pharmaceuticals, Inc. Methods of maintaining, treating or improving cognitive function
DE102012016908A1 (de) 2012-08-17 2014-02-20 Aicuris Gmbh & Co. Kg Tris-(Hetero)Aryl-Pyrazole und ihre Verwendung
BR112019002733A2 (pt) 2016-08-11 2019-05-14 Bayer Cropscience Ag derivados de pirazolinil substituídos, processos para sua preparação e seu uso como herbicidas e/ou reguladores de crescimento da planta
WO2019000236A1 (en) * 2017-06-27 2019-01-03 Merck Sharp & Dohme Corp. ALLOSTERIC MODULATORS OF 3- (1H-PYRAZOL-4-YL) PYRIDINE FROM THE M4 ACETYLCHOLINE MUSCARINIC RECEPTOR

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0248523B1 (en) 1986-05-07 1991-10-16 FISONS plc Pyrazoles
FR2862647B1 (fr) * 2003-11-25 2008-07-04 Aventis Pharma Sa Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant
WO2006064375A2 (en) * 2004-12-16 2006-06-22 Ab Science Aminoaryl substituted five-membered ring heterocyclic compounds for the treatment of diseases
CN101263130B (zh) * 2005-09-13 2011-03-09 詹森药业有限公司 2-苯胺-4-芳基取代的噻唑衍生物
JO3019B1 (ar) * 2006-04-19 2016-09-05 Janssen Pharmaceutica Nv ثلاثي مستبدل 4،2،1-ثلاثي زولات
BRPI0912196A2 (pt) 2008-05-09 2015-10-06 Janssen Pharmaceutica Nv pirazóis trissubstituídos como moduladores do receptor de acetilcolina.

Also Published As

Publication number Publication date
US8791144B2 (en) 2014-07-29
WO2011033018A1 (en) 2011-03-24
CN102574832A (zh) 2012-07-11
BR112012005960A2 (pt) 2016-03-15
EA020564B1 (ru) 2014-12-30
ES2446356T3 (es) 2014-03-07
CA2770932A1 (en) 2011-03-24
CA2770932C (en) 2017-04-25
JP2013505217A (ja) 2013-02-14
CN102574832B (zh) 2014-09-24
US20120172354A1 (en) 2012-07-05
EP2491024A1 (en) 2012-08-29
KR20120089805A (ko) 2012-08-13
JP5636428B2 (ja) 2014-12-03
KR101710197B1 (ko) 2017-02-24
EP2491024B1 (en) 2013-11-20
AU2010297263A1 (en) 2012-03-01
AU2010297263B2 (en) 2014-07-10
EA201270428A1 (ru) 2012-08-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230920