HK1168588A1 - Process for the preparation of derivatives of 1-(2-halobiphenyl-4-yl)- cyclopropanecarboxylic acid 1-(2--4-)- - Google Patents
Process for the preparation of derivatives of 1-(2-halobiphenyl-4-yl)- cyclopropanecarboxylic acid 1-(2--4-)-Info
- Publication number
- HK1168588A1 HK1168588A1 HK12109297.7A HK12109297A HK1168588A1 HK 1168588 A1 HK1168588 A1 HK 1168588A1 HK 12109297 A HK12109297 A HK 12109297A HK 1168588 A1 HK1168588 A1 HK 1168588A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- halobiphenyl
- derivatives
- preparation
- cyclopropanecarboxylic acid
- cyclopropanecarboxylic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/14—Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/54—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36
- B01J23/56—Platinum group metals
- B01J23/58—Platinum group metals with alkali- or alkaline earth metals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Materials Engineering (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hospice & Palliative Care (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09167206 | 2009-08-04 | ||
| PCT/EP2010/004481 WO2011015287A2 (fr) | 2009-08-04 | 2010-07-22 | Procédé pour la préparation de dérivés dacide 1-(2-halogénobiphényl-4-yl)-cyclopropanecarboxylique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1168588A1 true HK1168588A1 (en) | 2013-01-04 |
Family
ID=41479261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12109297.7A HK1168588A1 (en) | 2009-08-04 | 2012-09-21 | Process for the preparation of derivatives of 1-(2-halobiphenyl-4-yl)- cyclopropanecarboxylic acid 1-(2--4-)- |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9056818B2 (fr) |
| EP (1) | EP2462098B1 (fr) |
| JP (2) | JP5996428B2 (fr) |
| KR (1) | KR101737653B1 (fr) |
| CN (1) | CN102596879B (fr) |
| AU (1) | AU2010281069B2 (fr) |
| BR (1) | BR112012002500A2 (fr) |
| CA (1) | CA2769960C (fr) |
| DK (1) | DK2462098T3 (fr) |
| ES (1) | ES2437163T3 (fr) |
| HK (1) | HK1168588A1 (fr) |
| HR (1) | HRP20140032T1 (fr) |
| IL (1) | IL217886A (fr) |
| MX (1) | MX2012001411A (fr) |
| MY (1) | MY152980A (fr) |
| PT (1) | PT2462098E (fr) |
| RU (1) | RU2540076C2 (fr) |
| SG (1) | SG178239A1 (fr) |
| SI (1) | SI2462098T1 (fr) |
| UA (1) | UA106619C2 (fr) |
| WO (1) | WO2011015287A2 (fr) |
| ZA (1) | ZA201200821B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2133322A1 (fr) * | 2008-06-11 | 2009-12-16 | CHIESI FARMACEUTICI S.p.A. | Procédé de préparation de dérivés d'acide 1-(2-halobiphényl-4-yl)-cyclopropanecardxylique |
| WO2011015287A2 (fr) * | 2009-08-04 | 2011-02-10 | Chiesi Farmaceutici S.P.A. | Procédé pour la préparation de dérivés dacide 1-(2-halogénobiphényl-4-yl)-cyclopropanecarboxylique |
| CN106431900A (zh) | 2010-04-01 | 2017-02-22 | 奇斯药制品公司 | 新的多晶型物和盐 |
| US8975438B2 (en) * | 2011-07-13 | 2015-03-10 | Hoffmann-La Roche Inc. | Process for the preparation of cyclohexanecarboxylic acid derivatives |
| US9592210B2 (en) | 2011-12-22 | 2017-03-14 | Chiesi Farmaceutici S.P.A. | 1-phenylalkanecarboxylic acid derivatives for the treatment of cognitive impairment |
| CA2869418A1 (fr) | 2012-04-04 | 2013-10-10 | Chiesi Farmaceutici S.P.A. | Derives d'acides 1-(2-halo-biphenyl-4-yl)alcanecarboxyliques pour le traitement de maladies neurodegeneratives |
| EP2818460A1 (fr) | 2013-06-24 | 2014-12-31 | ZaCh System S.p.A. | Cyclopropanation de phénylacétonitriles substitués ou acétates de phényle |
| KR20160021772A (ko) * | 2013-06-24 | 2016-02-26 | 키에시 파르마슈티시 엣스. 피. 에이. | 1-(2-플루오로［1,1′-비페닐］-4-일)-시클로프로판카복실산의 유도체의 개선된 제조 방법 |
| WO2023034184A1 (fr) | 2021-08-31 | 2023-03-09 | Cerespir Incorporated | Co-cristaux |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20030311A1 (it) * | 2003-02-21 | 2004-08-22 | Chiesi Farma Spa | Acidi 2-fenil-2-dialchil-acetici per il trattamento della malattia di alzheimer. |
| EP1594833B1 (fr) | 2003-02-21 | 2008-09-24 | CHIESI FARMACEUTICI S.p.A. | Derives d'acide 1-phenylalcane-carboxylique pour le traitement de maladies neurodegeneratives |
| JP2005047842A (ja) * | 2003-07-31 | 2005-02-24 | Mitsubishi Chemicals Corp | 有機化合物の製造方法 |
| EP1650183A1 (fr) * | 2004-10-21 | 2006-04-26 | Cellzome Ag | L'acides acétiques (de benzyloxy-biphenyle) et de leurs derives ainsi que leurs utilisation en thérapie |
| EP1893562A4 (fr) * | 2005-06-14 | 2010-04-28 | Merck Frosst Canada Ltd | Inhibiteurs reversibles des monoamines oxydases a et b |
| RU2470918C2 (ru) * | 2007-01-15 | 2012-12-27 | Сантен Фармасьютикал Ко., Лтд. | НОВЫЕ ПРОИЗВОДНЫЕ ИНДОЛА, ОБЛАДАЮЩИЕ ИНГИБИРУЮЩЕЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ IκB КИНАЗЫ β |
| EP2133322A1 (fr) * | 2008-06-11 | 2009-12-16 | CHIESI FARMACEUTICI S.p.A. | Procédé de préparation de dérivés d'acide 1-(2-halobiphényl-4-yl)-cyclopropanecardxylique |
| WO2011015287A2 (fr) * | 2009-08-04 | 2011-02-10 | Chiesi Farmaceutici S.P.A. | Procédé pour la préparation de dérivés dacide 1-(2-halogénobiphényl-4-yl)-cyclopropanecarboxylique |
-
2010
- 2010-07-22 WO PCT/EP2010/004481 patent/WO2011015287A2/fr active Application Filing
- 2010-07-22 KR KR1020127001858A patent/KR101737653B1/ko active IP Right Grant
- 2010-07-22 RU RU2012104795/04A patent/RU2540076C2/ru active
- 2010-07-22 JP JP2012523221A patent/JP5996428B2/ja active Active
- 2010-07-22 DK DK10742083.8T patent/DK2462098T3/da active
- 2010-07-22 MY MYPI2012000462 patent/MY152980A/en unknown
- 2010-07-22 MX MX2012001411A patent/MX2012001411A/es active IP Right Grant
- 2010-07-22 EP EP10742083.8A patent/EP2462098B1/fr active Active
- 2010-07-22 CN CN201080034395.7A patent/CN102596879B/zh not_active Expired - Fee Related
- 2010-07-22 SI SI201030468T patent/SI2462098T1/sl unknown
- 2010-07-22 ES ES10742083.8T patent/ES2437163T3/es active Active
- 2010-07-22 BR BR112012002500A patent/BR112012002500A2/pt not_active IP Right Cessation
- 2010-07-22 PT PT107420838T patent/PT2462098E/pt unknown
- 2010-07-22 SG SG2012007548A patent/SG178239A1/en unknown
- 2010-07-22 UA UAA201200649A patent/UA106619C2/uk unknown
- 2010-07-22 CA CA2769960A patent/CA2769960C/fr not_active Expired - Fee Related
- 2010-07-22 AU AU2010281069A patent/AU2010281069B2/en not_active Ceased
- 2010-07-29 US US12/846,341 patent/US9056818B2/en active Active
-
2012
- 2012-02-02 IL IL217886A patent/IL217886A/en not_active IP Right Cessation
- 2012-02-02 ZA ZA2012/00821A patent/ZA201200821B/en unknown
- 2012-09-21 HK HK12109297.7A patent/HK1168588A1/xx not_active IP Right Cessation
-
2014
- 2014-01-13 HR HRP20140032AT patent/HRP20140032T1/hr unknown
-
2015
- 2015-02-25 JP JP2015034663A patent/JP6001112B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2012104795A (ru) | 2013-09-10 |
| JP5996428B2 (ja) | 2016-09-21 |
| JP6001112B2 (ja) | 2016-10-05 |
| IL217886A0 (en) | 2012-03-29 |
| CN102596879B (zh) | 2015-01-28 |
| CA2769960A1 (fr) | 2011-02-10 |
| DK2462098T3 (da) | 2013-11-25 |
| EP2462098A2 (fr) | 2012-06-13 |
| UA106619C2 (uk) | 2014-09-25 |
| KR101737653B1 (ko) | 2017-05-18 |
| WO2011015287A3 (fr) | 2011-03-31 |
| US9056818B2 (en) | 2015-06-16 |
| AU2010281069A1 (en) | 2012-02-23 |
| ES2437163T3 (es) | 2014-01-09 |
| IL217886A (en) | 2014-11-30 |
| PT2462098E (pt) | 2013-12-04 |
| CA2769960C (fr) | 2017-04-18 |
| BR112012002500A2 (pt) | 2018-03-13 |
| MX2012001411A (es) | 2012-03-29 |
| ZA201200821B (en) | 2013-05-29 |
| MY152980A (en) | 2014-12-15 |
| US20110039934A1 (en) | 2011-02-17 |
| EP2462098B1 (fr) | 2013-10-23 |
| JP2015131824A (ja) | 2015-07-23 |
| WO2011015287A2 (fr) | 2011-02-10 |
| RU2540076C2 (ru) | 2015-01-27 |
| HRP20140032T1 (hr) | 2014-02-14 |
| SG178239A1 (en) | 2012-03-29 |
| SI2462098T1 (sl) | 2014-01-31 |
| JP2013501010A (ja) | 2013-01-10 |
| CN102596879A (zh) | 2012-07-18 |
| KR20120050977A (ko) | 2012-05-21 |
| AU2010281069B2 (en) | 2015-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20220722 |