HK1168588A1 - 製備 -鹵代聯苯- -基 -環丙烷羧酸的衍生物的方法 - Google Patents
製備 -鹵代聯苯- -基 -環丙烷羧酸的衍生物的方法Info
- Publication number
- HK1168588A1 HK1168588A1 HK12109297.7A HK12109297A HK1168588A1 HK 1168588 A1 HK1168588 A1 HK 1168588A1 HK 12109297 A HK12109297 A HK 12109297A HK 1168588 A1 HK1168588 A1 HK 1168588A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- halobiphenyl
- derivatives
- preparation
- cyclopropanecarboxylic acid
- cyclopropanecarboxylic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/14—Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/54—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36
- B01J23/56—Platinum group metals
- B01J23/58—Platinum group metals with alkali- or alkaline earth metals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Materials Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09167206 | 2009-08-04 | ||
| PCT/EP2010/004481 WO2011015287A2 (en) | 2009-08-04 | 2010-07-22 | Process for the preparation of derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1168588A1 true HK1168588A1 (zh) | 2013-01-04 |
Family
ID=41479261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12109297.7A HK1168588A1 (zh) | 2009-08-04 | 2012-09-21 | 製備 -鹵代聯苯- -基 -環丙烷羧酸的衍生物的方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9056818B2 (zh) |
| EP (1) | EP2462098B1 (zh) |
| JP (2) | JP5996428B2 (zh) |
| KR (1) | KR101737653B1 (zh) |
| CN (1) | CN102596879B (zh) |
| AU (1) | AU2010281069B2 (zh) |
| BR (1) | BR112012002500A2 (zh) |
| CA (1) | CA2769960C (zh) |
| DK (1) | DK2462098T3 (zh) |
| ES (1) | ES2437163T3 (zh) |
| HK (1) | HK1168588A1 (zh) |
| HR (1) | HRP20140032T1 (zh) |
| IL (1) | IL217886A (zh) |
| MX (1) | MX2012001411A (zh) |
| MY (1) | MY152980A (zh) |
| PT (1) | PT2462098E (zh) |
| RU (1) | RU2540076C2 (zh) |
| SG (1) | SG178239A1 (zh) |
| SI (1) | SI2462098T1 (zh) |
| UA (1) | UA106619C2 (zh) |
| WO (1) | WO2011015287A2 (zh) |
| ZA (1) | ZA201200821B (zh) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2133322A1 (en) * | 2008-06-11 | 2009-12-16 | CHIESI FARMACEUTICI S.p.A. | Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid |
| CN102596879B (zh) * | 2009-08-04 | 2015-01-28 | 奇斯药制品公司 | 制备1-(2-卤代联苯-4-基)-环丙烷羧酸的衍生物的方法 |
| CA2794940A1 (en) | 2010-04-01 | 2011-10-06 | Chiesi Farmaceutici S.P.A. | Novel polymorphs and salts |
| US8975438B2 (en) * | 2011-07-13 | 2015-03-10 | Hoffmann-La Roche Inc. | Process for the preparation of cyclohexanecarboxylic acid derivatives |
| US9592210B2 (en) | 2011-12-22 | 2017-03-14 | Chiesi Farmaceutici S.P.A. | 1-phenylalkanecarboxylic acid derivatives for the treatment of cognitive impairment |
| US8835494B2 (en) | 2012-04-04 | 2014-09-16 | Chiesi Farmaceutici S.P.A. | Derivatives of 1-(2-halo-biphenyl-4-yl)-Alkanecarboxylic for the treatment of neurodegenerative diseases |
| EP3013786B1 (en) | 2013-06-24 | 2018-04-04 | Chiesi Farmaceutici S.p.A. | Improved process for the preparation of derivatives of 1-(2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid |
| EP2818460A1 (en) | 2013-06-24 | 2014-12-31 | ZaCh System S.p.A. | Cyclopropanation of substituted phenylacetonitriles or phenyl acetates |
| CN117897174A (zh) | 2021-08-31 | 2024-04-16 | 塞雷斯皮尔股份有限公司 | 共晶 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20030311A1 (it) * | 2003-02-21 | 2004-08-22 | Chiesi Farma Spa | Acidi 2-fenil-2-dialchil-acetici per il trattamento della malattia di alzheimer. |
| ATE409176T1 (de) * | 2003-02-21 | 2008-10-15 | Chiesi Farma Spa | 1-phenylalkancarbonsäurederivate zur behandlung neurodegenerativer erkrankungen |
| JP2005047842A (ja) * | 2003-07-31 | 2005-02-24 | Mitsubishi Chemicals Corp | 有機化合物の製造方法 |
| EP1650183A1 (en) * | 2004-10-21 | 2006-04-26 | Cellzome Ag | (Benzyloxy-biphenyl) acetic acids and derivatives thereof and their use in therapy |
| AU2006257670A1 (en) * | 2005-06-14 | 2006-12-21 | Merck Frosst Canada Ltd | Reversible inhibitors of monoamine oxidase A and B |
| WO2008087933A1 (ja) * | 2007-01-15 | 2008-07-24 | Santen Pharmaceutical Co., Ltd. | ＩκＢキナーゼβ阻害活性を有する新規インドール誘導体 |
| EP2133322A1 (en) * | 2008-06-11 | 2009-12-16 | CHIESI FARMACEUTICI S.p.A. | Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid |
| CN102596879B (zh) * | 2009-08-04 | 2015-01-28 | 奇斯药制品公司 | 制备1-(2-卤代联苯-4-基)-环丙烷羧酸的衍生物的方法 |
-
2010
- 2010-07-22 CN CN201080034395.7A patent/CN102596879B/zh not_active Expired - Fee Related
- 2010-07-22 RU RU2012104795/04A patent/RU2540076C2/ru active
- 2010-07-22 EP EP10742083.8A patent/EP2462098B1/en active Active
- 2010-07-22 WO PCT/EP2010/004481 patent/WO2011015287A2/en active Application Filing
- 2010-07-22 KR KR1020127001858A patent/KR101737653B1/ko active IP Right Grant
- 2010-07-22 ES ES10742083.8T patent/ES2437163T3/es active Active
- 2010-07-22 AU AU2010281069A patent/AU2010281069B2/en not_active Ceased
- 2010-07-22 MX MX2012001411A patent/MX2012001411A/es active IP Right Grant
- 2010-07-22 MY MYPI2012000462 patent/MY152980A/en unknown
- 2010-07-22 UA UAA201200649A patent/UA106619C2/uk unknown
- 2010-07-22 BR BR112012002500A patent/BR112012002500A2/pt not_active IP Right Cessation
- 2010-07-22 CA CA2769960A patent/CA2769960C/en not_active Expired - Fee Related
- 2010-07-22 PT PT107420838T patent/PT2462098E/pt unknown
- 2010-07-22 SI SI201030468T patent/SI2462098T1/sl unknown
- 2010-07-22 SG SG2012007548A patent/SG178239A1/en unknown
- 2010-07-22 DK DK10742083.8T patent/DK2462098T3/da active
- 2010-07-22 JP JP2012523221A patent/JP5996428B2/ja active Active
- 2010-07-29 US US12/846,341 patent/US9056818B2/en active Active
-
2012
- 2012-02-02 IL IL217886A patent/IL217886A/en not_active IP Right Cessation
- 2012-02-02 ZA ZA2012/00821A patent/ZA201200821B/en unknown
- 2012-09-21 HK HK12109297.7A patent/HK1168588A1/zh not_active IP Right Cessation
-
2014
- 2014-01-13 HR HRP20140032AT patent/HRP20140032T1/hr unknown
-
2015
- 2015-02-25 JP JP2015034663A patent/JP6001112B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013501010A (ja) | 2013-01-10 |
| WO2011015287A3 (en) | 2011-03-31 |
| JP2015131824A (ja) | 2015-07-23 |
| KR20120050977A (ko) | 2012-05-21 |
| ES2437163T3 (es) | 2014-01-09 |
| JP5996428B2 (ja) | 2016-09-21 |
| JP6001112B2 (ja) | 2016-10-05 |
| PT2462098E (pt) | 2013-12-04 |
| SG178239A1 (en) | 2012-03-29 |
| KR101737653B1 (ko) | 2017-05-18 |
| US9056818B2 (en) | 2015-06-16 |
| DK2462098T3 (da) | 2013-11-25 |
| AU2010281069A1 (en) | 2012-02-23 |
| CN102596879B (zh) | 2015-01-28 |
| CN102596879A (zh) | 2012-07-18 |
| US20110039934A1 (en) | 2011-02-17 |
| AU2010281069B2 (en) | 2015-09-10 |
| HRP20140032T1 (hr) | 2014-02-14 |
| CA2769960C (en) | 2017-04-18 |
| EP2462098A2 (en) | 2012-06-13 |
| EP2462098B1 (en) | 2013-10-23 |
| RU2012104795A (ru) | 2013-09-10 |
| BR112012002500A2 (pt) | 2018-03-13 |
| WO2011015287A2 (en) | 2011-02-10 |
| MX2012001411A (es) | 2012-03-29 |
| IL217886A (en) | 2014-11-30 |
| ZA201200821B (en) | 2013-05-29 |
| IL217886A0 (en) | 2012-03-29 |
| CA2769960A1 (en) | 2011-02-10 |
| UA106619C2 (uk) | 2014-09-25 |
| SI2462098T1 (sl) | 2014-01-31 |
| RU2540076C2 (ru) | 2015-01-27 |
| MY152980A (en) | 2014-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20220722 |