HK1168509A1 - Dual vector for inhibition of human immunodeficiency virus - Google Patents
Dual vector for inhibition of human immunodeficiency virusInfo
- Publication number
- HK1168509A1 HK1168509A1 HK12109456.4A HK12109456A HK1168509A1 HK 1168509 A1 HK1168509 A1 HK 1168509A1 HK 12109456 A HK12109456 A HK 12109456A HK 1168509 A1 HK1168509 A1 HK 1168509A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- inhibition
- immunodeficiency virus
- human immunodeficiency
- dual vector
- dual
- Prior art date
Links
- 241000725303 Human immunodeficiency virus Species 0.000 title 1
- 230000009977 dual effect Effects 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
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- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0634—Cells from the blood or the immune system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/12—Animals modified by administration of exogenous cells
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0337—Animal models for infectious diseases
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- A—HUMAN NECESSITIES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
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- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C12N2310/531—Stem-loop; Hairpin
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- C12N2740/16171—Demonstrated in vivo effect
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- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Environmental Sciences (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22568709P | 2009-07-15 | 2009-07-15 | |
US28759909P | 2009-12-17 | 2009-12-17 | |
PCT/US2010/036247 WO2011008348A2 (en) | 2009-07-15 | 2010-05-26 | Dual vector for inhibition of human immunodeficiency virus |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1168509A1 true HK1168509A1 (en) | 2013-01-04 |
Family
ID=42797105
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK12109456.4A HK1168509A1 (en) | 2009-07-15 | 2012-09-25 | Dual vector for inhibition of human immunodeficiency virus |
Country Status (10)
Country | Link |
---|---|
US (3) | US20120201794A1 (ru) |
EP (4) | EP3659435A1 (ru) |
JP (4) | JP5828838B2 (ru) |
AU (1) | AU2010274031B2 (ru) |
CA (1) | CA2767972A1 (ru) |
DK (2) | DK3329772T3 (ru) |
ES (3) | ES2770627T3 (ru) |
HK (1) | HK1168509A1 (ru) |
RU (2) | RU2562868C2 (ru) |
WO (1) | WO2011008348A2 (ru) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100183558A1 (en) | 2008-10-17 | 2010-07-22 | Zhennan Lai | Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules |
GB201012410D0 (en) * | 2010-07-23 | 2010-09-08 | Medical Res Council | Intracellular immunity |
WO2013003410A2 (en) * | 2011-06-29 | 2013-01-03 | Ronilu Development Corporation | Prevention and treatment of hiv infection |
JP6516740B2 (ja) * | 2013-08-02 | 2019-05-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 幹細胞及びキメラ抗原受容体を介した抗腫瘍性t細胞免疫の改変 |
WO2016014837A1 (en) * | 2014-07-25 | 2016-01-28 | Sangamo Biosciences, Inc. | Gene editing for hiv gene therapy |
SG11201703281RA (en) | 2014-11-14 | 2017-05-30 | Voyager Therapeutics Inc | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
AU2016261864B2 (en) | 2015-05-13 | 2022-05-26 | Csl Behring Gene Therapy, Inc. | Bio-production of lentiviral vectors |
AU2016265003A1 (en) | 2015-05-18 | 2017-12-07 | Csl Behring Gene Therapy, Inc. | Gene therapeutic for the treatment of HIV and uses thereof |
CA2986133A1 (en) | 2015-05-18 | 2016-11-24 | Calimmune, Inc. | Methods of discriminating between hiv-1 and lentiviral vectors |
JP6890831B2 (ja) * | 2015-07-08 | 2021-06-18 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | Hiv予備免疫化および免疫療法 |
US10137144B2 (en) | 2016-01-15 | 2018-11-27 | American Gene Technologies International Inc. | Methods and compositions for the activation of gamma-delta T-cells |
EP3402483B1 (en) | 2016-01-15 | 2023-11-08 | American Gene Technologies International Inc. | Methods and compositons for the activation of gamma-delta t-cells |
EP3413926A4 (en) * | 2016-02-08 | 2019-10-09 | American Gene Technologies International, Inc. | HIV VACCINATION AND IMMUNOTHERAPY |
EP3426777B1 (en) | 2016-03-09 | 2022-02-16 | American Gene Technologies International Inc. | Combination vectors and methods for treating cancer |
CN105861559B (zh) * | 2016-04-11 | 2018-05-01 | 苏州奥特铭医药科技有限公司 | 一种能直接反应i型干扰素应答的慢病毒载体及其制备方法与应用 |
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JP2016013128A (ja) | 2016-01-28 |
JP2019122413A (ja) | 2019-07-25 |
RU2562868C2 (ru) | 2015-09-10 |
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EP2453735B1 (en) | 2015-07-08 |
JP6247259B2 (ja) | 2017-12-13 |
EP3329772A1 (en) | 2018-06-06 |
CA2767972A1 (en) | 2011-01-20 |
US20160243169A1 (en) | 2016-08-25 |
ES2657737T3 (es) | 2018-03-06 |
EP2949208B1 (en) | 2017-11-15 |
DK2949208T3 (en) | 2018-01-22 |
JP2012533299A (ja) | 2012-12-27 |
JP6840189B2 (ja) | 2021-03-10 |
AU2010274031B2 (en) | 2015-07-16 |
EP2453735A2 (en) | 2012-05-23 |
WO2011008348A3 (en) | 2011-03-10 |
ES2770627T3 (es) | 2020-07-02 |
RU2012105281A (ru) | 2013-08-20 |
EP3659435A1 (en) | 2020-06-03 |
JP5828838B2 (ja) | 2015-12-09 |
US20120201794A1 (en) | 2012-08-09 |
EP2949208A1 (en) | 2015-12-02 |
WO2011008348A2 (en) | 2011-01-20 |
US20220016176A1 (en) | 2022-01-20 |
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