HK116797A - Alicyclic phospholipase A2 inhibitors - Google Patents

Alicyclic phospholipase A2 inhibitors

Info

Publication number
HK116797A
HK116797A HK116797A HK116797A HK116797A HK 116797 A HK116797 A HK 116797A HK 116797 A HK116797 A HK 116797A HK 116797 A HK116797 A HK 116797A HK 116797 A HK116797 A HK 116797A
Authority
HK
Hong Kong
Prior art keywords
inhibitors
phospholipase
alicyclic
pla2
certain novel
Prior art date
Application number
HK116797A
Other languages
English (en)
Inventor
Joanne J Bronson
F Ivy Carroll
Katharine M Greene
Anita Lewin
Muzammil M Mansuri
Andrea Stanley V D
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/200,798 external-priority patent/US5436369A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of HK116797A publication Critical patent/HK116797A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/66—Polycyclic acids with unsaturation outside the aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/618—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/65—Halogen-containing esters of unsaturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24—Anthracenes; Hydrogenated anthracenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HK116797A 1993-06-16 1997-06-26 Alicyclic phospholipase A2 inhibitors HK116797A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7907293A 1993-06-16 1993-06-16
US08/200,798 US5436369A (en) 1993-06-16 1994-02-23 Alicyclic phospholipase A2 inhibitors

Publications (1)

Publication Number Publication Date
HK116797A true HK116797A (en) 1997-09-05

Family

ID=26761593

Family Applications (1)

Application Number Title Priority Date Filing Date
HK116797A HK116797A (en) 1993-06-16 1997-06-26 Alicyclic phospholipase A2 inhibitors

Country Status (22)

Country Link
EP (1) EP0629604B1 (ja)
JP (1) JPH0717913A (ja)
CN (1) CN1099380A (ja)
AT (1) ATE151742T1 (ja)
AU (1) AU667777B2 (ja)
CA (1) CA2125802A1 (ja)
CY (1) CY2020A (ja)
CZ (1) CZ288786B6 (ja)
DE (1) DE69402613T2 (ja)
DK (1) DK0629604T3 (ja)
ES (1) ES2102776T3 (ja)
FI (1) FI942796A (ja)
GR (1) GR3024104T3 (ja)
HK (1) HK116797A (ja)
HU (1) HU222521B1 (ja)
IL (1) IL110013A (ja)
NO (1) NO301417B1 (ja)
NZ (1) NZ260735A (ja)
PL (1) PL176790B1 (ja)
SG (1) SG50539A1 (ja)
TW (1) TW419461B (ja)
ZA (1) ZA944227B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1764405A1 (en) * 2005-09-20 2007-03-21 Rolic AG Functionalized photoreactive compounds
RU2453536C2 (ru) * 2007-10-22 2012-06-20 Оркид Рисерч Лабораториз Лимитед Ингибиторы гистондезацетилазы

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS244440B2 (en) * 1983-02-28 1986-07-17 Celamerck Gmbh & Co Kg Method of acrylic acids' new amides production

Also Published As

Publication number Publication date
HU222521B1 (hu) 2003-08-28
NO942244L (no) 1994-12-19
DK0629604T3 (da) 1997-09-15
SG50539A1 (en) 1998-07-20
IL110013A0 (en) 1994-10-07
AU667777B2 (en) 1996-04-04
ZA944227B (en) 1995-02-10
AU6466694A (en) 1994-12-22
CZ288786B6 (cs) 2001-09-12
CZ147294A3 (en) 1995-01-18
ES2102776T3 (es) 1997-08-01
CY2020A (en) 1998-02-20
HUT70550A (en) 1995-10-30
PL176790B1 (pl) 1999-07-30
DE69402613T2 (de) 1997-10-30
FI942796A (fi) 1994-12-17
CA2125802A1 (en) 1994-12-17
NO301417B1 (no) 1997-10-27
EP0629604B1 (en) 1997-04-16
GR3024104T3 (en) 1997-10-31
ATE151742T1 (de) 1997-05-15
JPH0717913A (ja) 1995-01-20
NZ260735A (en) 1996-12-20
NO942244D0 (no) 1994-06-15
EP0629604A2 (en) 1994-12-21
DE69402613D1 (de) 1997-05-22
TW419461B (en) 2001-01-21
FI942796A0 (fi) 1994-06-13
PL303862A1 (en) 1994-12-27
HU9401789D0 (en) 1994-09-28
IL110013A (en) 1998-07-15
CN1099380A (zh) 1995-03-01
EP0629604A3 (en) 1995-03-01

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)