ATE151742T1 - Alicyclische phospholipase a 2 inhibitoren - Google Patents

Alicyclische phospholipase a 2 inhibitoren

Info

Publication number
ATE151742T1
ATE151742T1 AT94304337T AT94304337T ATE151742T1 AT E151742 T1 ATE151742 T1 AT E151742T1 AT 94304337 T AT94304337 T AT 94304337T AT 94304337 T AT94304337 T AT 94304337T AT E151742 T1 ATE151742 T1 AT E151742T1
Authority
AT
Austria
Prior art keywords
inhibitors
phospholipase
alicyclic
pla2
certain novel
Prior art date
Application number
AT94304337T
Other languages
English (en)
Inventor
Joanne J Bronson
F Ivy Carroll
Katharine M Greene
Anita Lewin
Muzammil M Mansuri
Andrea Stanley V D
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/200,798 external-priority patent/US5436369A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE151742T1 publication Critical patent/ATE151742T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/66Polycyclic acids with unsaturation outside the aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/618Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62Halogen-containing esters
    • C07C69/65Halogen-containing esters of unsaturated acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/24Anthracenes; Hydrogenated anthracenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/70Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT94304337T 1993-06-16 1994-06-15 Alicyclische phospholipase a 2 inhibitoren ATE151742T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7907293A 1993-06-16 1993-06-16
US08/200,798 US5436369A (en) 1993-06-16 1994-02-23 Alicyclic phospholipase A2 inhibitors

Publications (1)

Publication Number Publication Date
ATE151742T1 true ATE151742T1 (de) 1997-05-15

Family

ID=26761593

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94304337T ATE151742T1 (de) 1993-06-16 1994-06-15 Alicyclische phospholipase a 2 inhibitoren

Country Status (22)

Country Link
EP (1) EP0629604B1 (de)
JP (1) JPH0717913A (de)
CN (1) CN1099380A (de)
AT (1) ATE151742T1 (de)
AU (1) AU667777B2 (de)
CA (1) CA2125802A1 (de)
CY (1) CY2020A (de)
CZ (1) CZ288786B6 (de)
DE (1) DE69402613T2 (de)
DK (1) DK0629604T3 (de)
ES (1) ES2102776T3 (de)
FI (1) FI942796A (de)
GR (1) GR3024104T3 (de)
HK (1) HK116797A (de)
HU (1) HU222521B1 (de)
IL (1) IL110013A (de)
NO (1) NO301417B1 (de)
NZ (1) NZ260735A (de)
PL (1) PL176790B1 (de)
SG (1) SG50539A1 (de)
TW (1) TW419461B (de)
ZA (1) ZA944227B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1764405A1 (de) * 2005-09-20 2007-03-21 Rolic AG Funktionalisierte photoreaktive Verbindungen
RU2453536C2 (ru) * 2007-10-22 2012-06-20 Оркид Рисерч Лабораториз Лимитед Ингибиторы гистондезацетилазы

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS244440B2 (en) * 1983-02-28 1986-07-17 Celamerck Gmbh & Co Kg Method of acrylic acids' new amides production

Also Published As

Publication number Publication date
HU222521B1 (hu) 2003-08-28
NO942244L (no) 1994-12-19
DK0629604T3 (da) 1997-09-15
SG50539A1 (en) 1998-07-20
IL110013A0 (en) 1994-10-07
AU667777B2 (en) 1996-04-04
HK116797A (en) 1997-09-05
ZA944227B (en) 1995-02-10
AU6466694A (en) 1994-12-22
CZ288786B6 (cs) 2001-09-12
CZ147294A3 (en) 1995-01-18
ES2102776T3 (es) 1997-08-01
CY2020A (en) 1998-02-20
HUT70550A (en) 1995-10-30
PL176790B1 (pl) 1999-07-30
DE69402613T2 (de) 1997-10-30
FI942796A (fi) 1994-12-17
CA2125802A1 (en) 1994-12-17
NO301417B1 (no) 1997-10-27
EP0629604B1 (de) 1997-04-16
GR3024104T3 (en) 1997-10-31
JPH0717913A (ja) 1995-01-20
NZ260735A (en) 1996-12-20
NO942244D0 (no) 1994-06-15
EP0629604A2 (de) 1994-12-21
DE69402613D1 (de) 1997-05-22
TW419461B (en) 2001-01-21
FI942796A0 (fi) 1994-06-13
PL303862A1 (en) 1994-12-27
HU9401789D0 (en) 1994-09-28
IL110013A (en) 1998-07-15
CN1099380A (zh) 1995-03-01
EP0629604A3 (de) 1995-03-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee