HK1167865A1 - 地加瑞克的製造方法 - Google Patents

地加瑞克的製造方法

Info

Publication number
HK1167865A1
HK1167865A1 HK12108504.8A HK12108504A HK1167865A1 HK 1167865 A1 HK1167865 A1 HK 1167865A1 HK 12108504 A HK12108504 A HK 12108504A HK 1167865 A1 HK1167865 A1 HK 1167865A1
Authority
HK
Hong Kong
Prior art keywords
degarelix
manufacture
Prior art date
Application number
HK12108504.8A
Other languages
English (en)
Inventor
．張
．弗姆斯加德
．斯泰卡爾
Original Assignee
多肽實驗室聯合股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42494847&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1167865(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 多肽實驗室聯合股份有限公司 filed Critical 多肽實驗室聯合股份有限公司
Publication of HK1167865A1 publication Critical patent/HK1167865A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
HK12108504.8A 2009-04-24 2012-08-30 地加瑞克的製造方法 HK1167865A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0900558 2009-04-24
PCT/EP2010/002550 WO2010121835A1 (en) 2009-04-24 2010-04-26 Method for the manufacture of degarelix

Publications (1)

Publication Number Publication Date
HK1167865A1 true HK1167865A1 (zh) 2012-12-14

Family

ID=42494847

Family Applications (1)

Application Number Title Priority Date Filing Date
HK12108504.8A HK1167865A1 (zh) 2009-04-24 2012-08-30 地加瑞克的製造方法

Country Status (18)

Country Link
US (1) US8828938B2 (zh)
EP (1) EP2421887B1 (zh)
JP (1) JP5850458B2 (zh)
KR (1) KR101621725B1 (zh)
CN (1) CN102428097B (zh)
AU (1) AU2010241171B2 (zh)
CA (1) CA2759255C (zh)
DK (1) DK2421887T3 (zh)
ES (1) ES2538828T3 (zh)
HK (1) HK1167865A1 (zh)
HU (1) HUE025732T2 (zh)
IL (1) IL215846A (zh)
NZ (1) NZ595888A (zh)
PL (1) PL2421887T3 (zh)
RU (1) RU2515555C2 (zh)
SG (1) SG175744A1 (zh)
WO (1) WO2010121835A1 (zh)
ZA (1) ZA201107709B (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20090061B1 (ar) 2008-02-11 2021-08-17 Ferring Int Center Sa طريقة معالجة سرطان البروستاتا بمضادات الهرمونات التناسلية GnRH
WO2011066386A1 (en) 2009-11-25 2011-06-03 Novetide, Ltd. Process for production of degarelix
ES2617336T3 (es) * 2010-10-27 2017-06-16 Ferring B.V. Procedimiento para la fabricación de degarelix y sus productos intermedios
EP2447276A1 (en) * 2010-10-27 2012-05-02 Ferring B.V. Process for the manufacture of Degarelix and its intermediates
CN102329373B (zh) * 2011-09-29 2014-10-22 深圳翰宇药业股份有限公司 地加瑞克的固相合成工艺
MX364010B (es) 2012-06-01 2019-04-11 Ferring Bv Manufactura de degarelix.
CN102952174A (zh) * 2012-11-16 2013-03-06 济南环肽医药科技有限公司 一种地加瑞克的合成方法
CN103351428B (zh) * 2013-08-05 2016-09-07 海南双成药业股份有限公司 一种固相片段法合成地加瑞克
CN103992392B (zh) * 2014-05-19 2017-05-31 泰州启瑞医药科技有限公司 一种地加瑞克的固相合成方法
CN104177478B (zh) * 2014-08-27 2018-04-03 成都圣诺生物制药有限公司 一种合成地加瑞克的方法
CN104292394B (zh) * 2014-09-19 2017-02-08 深圳微球科技有限公司 一种Rink酰胺树脂的制备方法
CN105085634A (zh) * 2015-08-29 2015-11-25 中肽生化有限公司 一种地加瑞克的制备方法
US11168114B2 (en) 2015-12-17 2021-11-09 Fresenius Kabi iPSUM S.r.l Process for the manufacture of degarelix and its intermediates
CN105524143B (zh) * 2016-03-10 2019-01-22 成都圣诺生物制药有限公司 一种合成地加瑞克的方法
CN109929012B (zh) * 2017-12-15 2023-07-28 连云港恒运药业有限公司 地加瑞克关键四肽中间体的制备方法
CN109575109B (zh) * 2018-12-27 2022-03-25 兰州大学 片段缩合制备地加瑞克的方法
CA3132751A1 (en) 2019-03-07 2020-09-10 Fresenius Kabi Ipsum S.R.L. Process for the preparation of degarelix
US11332495B2 (en) 2019-09-21 2022-05-17 RK Pharma Solutions LLC Process for the preparation of Degarelix acetate and Degarelix acetate-mannitol premix
US20230024202A1 (en) * 2019-12-05 2023-01-26 Fresenius Kabi Usa, Llc Method for analyzing degarelix and associated products

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925730A (en) * 1997-04-11 1999-07-20 Ferring Bv GnRH antagonists
GB0307777D0 (en) * 2003-04-04 2003-05-07 Medical Res Council Conjugate compounds
CN100475271C (zh) * 2003-08-20 2009-04-08 加利福尼亚大学董事会 具有抑制生长激素释放活性的促生长素抑制素类似物

Also Published As

Publication number Publication date
PL2421887T3 (pl) 2015-11-30
CN102428097A (zh) 2012-04-25
CA2759255C (en) 2018-03-27
DK2421887T3 (en) 2015-07-27
IL215846A0 (en) 2012-01-31
EP2421887B1 (en) 2015-04-22
HUE025732T2 (en) 2016-04-28
RU2515555C2 (ru) 2014-05-10
US20120041172A1 (en) 2012-02-16
IL215846A (en) 2016-07-31
JP5850458B2 (ja) 2016-02-03
WO2010121835A1 (en) 2010-10-28
SG175744A1 (en) 2011-12-29
NZ595888A (en) 2013-05-31
KR101621725B1 (ko) 2016-05-17
US8828938B2 (en) 2014-09-09
RU2011142266A (ru) 2013-05-27
AU2010241171A1 (en) 2011-11-10
ZA201107709B (en) 2012-06-27
AU2010241171B2 (en) 2014-01-09
CA2759255A1 (en) 2010-10-28
CN102428097B (zh) 2014-10-29
EP2421887A1 (en) 2012-02-29
ES2538828T3 (es) 2015-06-24
KR20120030385A (ko) 2012-03-28
JP2012529425A (ja) 2012-11-22

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