HK1165797A1 - Imidazolidine-2,4-dione derivatives, and use thereof as a cancer drug - Google Patents
Imidazolidine-2,4-dione derivatives, and use thereof as a cancer drugInfo
- Publication number
- HK1165797A1 HK1165797A1 HK12106443.6A HK12106443A HK1165797A1 HK 1165797 A1 HK1165797 A1 HK 1165797A1 HK 12106443 A HK12106443 A HK 12106443A HK 1165797 A1 HK1165797 A1 HK 1165797A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- imidazolidine
- dione derivatives
- cancer drug
- materials
- cancer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C07D233/78—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0901865A FR2944524B1 (fr) | 2009-04-17 | 2009-04-17 | Derives d'imidazolidine-2,4-dione et leur utilisation comme medicament |
PCT/FR2010/000315 WO2010119193A1 (fr) | 2009-04-17 | 2010-04-16 | Derives d ' imidazolidine-2, 4-dione et leur utilisation comme medicament contre le cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1165797A1 true HK1165797A1 (en) | 2012-10-12 |
Family
ID=41349313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK12106443.6A HK1165797A1 (en) | 2009-04-17 | 2012-07-03 | Imidazolidine-2,4-dione derivatives, and use thereof as a cancer drug |
Country Status (14)
Country | Link |
---|---|
US (1) | US8710091B2 (ru) |
EP (1) | EP2419410B1 (ru) |
JP (1) | JP5730855B2 (ru) |
KR (1) | KR101678710B1 (ru) |
CN (1) | CN102428073B (ru) |
BR (1) | BRPI1014436A2 (ru) |
CA (1) | CA2758630C (ru) |
ES (1) | ES2405988T3 (ru) |
FR (1) | FR2944524B1 (ru) |
HK (1) | HK1165797A1 (ru) |
MX (1) | MX2011010693A (ru) |
RU (1) | RU2497812C2 (ru) |
UA (1) | UA107349C2 (ru) |
WO (1) | WO2010119193A1 (ru) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UY34646A (es) * | 2012-03-02 | 2013-10-31 | Novartis Ag | Compuestos de espirohidantoína y su uso como moduladores selectivos del receptor de andrógenos |
EP3089975B1 (en) * | 2013-12-31 | 2018-06-06 | Ipsen Pharma S.A.S. | Novel imidazolidine-2, 4-dione derivatives |
US9975880B2 (en) * | 2013-12-31 | 2018-05-22 | Ipsen Pharma S.A.S. | Imidazolidine-2,4-dione dervatives |
WO2015171585A1 (en) | 2014-05-05 | 2015-11-12 | The University Of Toledo | Biodegradable magnesium alloys and composites |
PL3292135T3 (pl) | 2015-05-06 | 2023-01-02 | Wageningen Universiteit | Zastosowanie polipeptydu do wpływania na sygnalizację odpornościową i/lub wpływania na funkcję bariery jelitowej i/lub modulowania stanu metabolicznego |
CN108289918B (zh) | 2015-09-10 | 2022-01-18 | 卢万天主教大学 | 经巴氏灭菌的艾克曼菌用于治疗代谢病症的用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2329276A1 (fr) * | 1975-10-29 | 1977-05-27 | Roussel Uclaf | Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant |
FR2693461B1 (fr) * | 1992-07-08 | 1994-09-02 | Roussel Uclaf | Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant. |
US5411981A (en) | 1991-01-09 | 1995-05-02 | Roussel Uclaf | Phenylimidazolidines having antiandrogenic activity |
FR2671348B1 (fr) | 1991-01-09 | 1993-03-26 | Roussel Uclaf | Nouvelles phenylimidazolidines, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant. |
JP3146596B2 (ja) * | 1992-03-10 | 2001-03-19 | 住友化学工業株式会社 | 3−ヒドロキシメチル−1−プロパルギルイミダゾリジン−2,4−ジオンの製造法 |
FR2715402B1 (fr) * | 1994-01-05 | 1996-10-04 | Roussel Uclaf | Nouvelles phénylimidazolines éventuellement substituées, leur procédé et des intermédiaires de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant. |
TW521073B (en) * | 1994-01-05 | 2003-02-21 | Hoechst Marion Roussel Inc | New optionally substituted phenylimidazolidines, their preparation process, their use as anti-androgenic agent and the pharmaceutical compositions containing them |
SE0100902D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
TW200523235A (en) * | 2003-10-15 | 2005-07-16 | Gtx Inc | Anti-cancer compounds and methods of use thereof |
TW200612920A (en) * | 2004-08-03 | 2006-05-01 | Chugai Pharmaceutical Co Ltd | Novel imidazolidine derivatives |
KR20080081359A (ko) * | 2006-01-30 | 2008-09-09 | 아이알엠 엘엘씨 | Ppar 조절제로서의 스피로 이미다졸 유도체 |
WO2007126765A2 (en) * | 2006-03-27 | 2007-11-08 | The Regents Of The University Of California | Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases |
-
2009
- 2009-04-17 FR FR0901865A patent/FR2944524B1/fr not_active Expired - Fee Related
-
2010
- 2010-04-16 US US13/264,971 patent/US8710091B2/en active Active
- 2010-04-16 MX MX2011010693A patent/MX2011010693A/es active IP Right Grant
- 2010-04-16 KR KR1020117027276A patent/KR101678710B1/ko active IP Right Grant
- 2010-04-16 ES ES10717193T patent/ES2405988T3/es active Active
- 2010-04-16 RU RU2011146641/04A patent/RU2497812C2/ru not_active IP Right Cessation
- 2010-04-16 CN CN201080021638.3A patent/CN102428073B/zh not_active Expired - Fee Related
- 2010-04-16 BR BRPI1014436A patent/BRPI1014436A2/pt not_active IP Right Cessation
- 2010-04-16 WO PCT/FR2010/000315 patent/WO2010119193A1/fr active Application Filing
- 2010-04-16 JP JP2012505196A patent/JP5730855B2/ja active Active
- 2010-04-16 CA CA2758630A patent/CA2758630C/fr not_active Expired - Fee Related
- 2010-04-16 EP EP10717193A patent/EP2419410B1/fr not_active Not-in-force
- 2010-04-16 UA UAA201113518A patent/UA107349C2/ru unknown
-
2012
- 2012-07-03 HK HK12106443.6A patent/HK1165797A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20120083514A1 (en) | 2012-04-05 |
BRPI1014436A2 (pt) | 2016-04-19 |
CA2758630A1 (fr) | 2010-10-21 |
KR20120016632A (ko) | 2012-02-24 |
JP5730855B2 (ja) | 2015-06-10 |
MX2011010693A (es) | 2011-10-28 |
KR101678710B1 (ko) | 2016-11-23 |
RU2497812C2 (ru) | 2013-11-10 |
RU2011146641A (ru) | 2013-05-27 |
US8710091B2 (en) | 2014-04-29 |
UA107349C2 (en) | 2014-12-25 |
EP2419410A1 (fr) | 2012-02-22 |
AU2010238380A1 (en) | 2011-11-10 |
CA2758630C (fr) | 2017-03-07 |
FR2944524A1 (fr) | 2010-10-22 |
ES2405988T3 (es) | 2013-06-04 |
CN102428073B (zh) | 2015-09-30 |
CN102428073A (zh) | 2012-04-25 |
EP2419410B1 (fr) | 2013-03-06 |
FR2944524B1 (fr) | 2012-11-30 |
WO2010119193A1 (fr) | 2010-10-21 |
JP2012524050A (ja) | 2012-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20210414 |