HK1163160A1 - 通過細菌性來源的完整小細胞向哺乳動物細胞遞送功能性核酸 - Google Patents

通過細菌性來源的完整小細胞向哺乳動物細胞遞送功能性核酸

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Publication number
HK1163160A1
HK1163160A1 HK12103437.1A HK12103437A HK1163160A1 HK 1163160 A1 HK1163160 A1 HK 1163160A1 HK 12103437 A HK12103437 A HK 12103437A HK 1163160 A1 HK1163160 A1 HK 1163160A1
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HK
Hong Kong
Prior art keywords
derived
nucleic acids
mammalian cells
cells via
functional nucleic
Prior art date
Application number
HK12103437.1A
Other languages
English (en)
Inventor
Himanshu Brahmbhatt
Jennifer Macdiarmid
Original Assignee
Engeneic Molecular Delivery Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Engeneic Molecular Delivery Pty Ltd filed Critical Engeneic Molecular Delivery Pty Ltd
Publication of HK1163160A1 publication Critical patent/HK1163160A1/zh

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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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HK12103437.1A 2004-08-26 2007-12-05 通過細菌性來源的完整小細胞向哺乳動物細胞遞送功能性核酸 HK1163160A1 (zh)

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US60443304P 2004-08-26 2004-08-26

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HK1163160A1 true HK1163160A1 (zh) 2012-09-07

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US (11) US8691963B2 (zh)
EP (2) EP1791959A4 (zh)
JP (1) JP4965447B2 (zh)
CN (2) CN102921019B (zh)
AU (2) AU2005276145C1 (zh)
CA (1) CA2577938C (zh)
DK (1) DK2386640T3 (zh)
ES (1) ES2535235T3 (zh)
HK (1) HK1163160A1 (zh)
HU (1) HUE024999T2 (zh)
MX (1) MX2007002294A (zh)
NZ (1) NZ553910A (zh)
PL (1) PL2386640T3 (zh)
PT (1) PT2386640E (zh)
SI (1) SI2386640T1 (zh)
WO (1) WO2006021894A2 (zh)

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US7611885B2 (en) * 2003-06-24 2009-11-03 Engeneic Molecular Delivery Pty, Ltd. Pharmaceutically compatible method for purifying intact bacterial minicells
ES2362881T3 (es) 2003-12-09 2011-07-14 Engeneic Molecular Delivery Pty Ltd. Administración génica dirigida a células de mamífero no fagocíticas a través de minicélulas intactas obtenidas de bacterias.
US8772013B2 (en) * 2004-02-02 2014-07-08 Engeneic Molecular Delivery Pty Ltd Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells
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HUE024999T2 (en) 2004-08-26 2016-02-29 Engeneic Molecular Delivery Pty Ltd Introducing functional nucleic acids into mammalian cells with bacterial intact minicells
EP2270136A1 (en) 2004-12-17 2011-01-05 Beth Israel Deaconess Medical Center Compositions for bacterial mediated gene silencing and methods of using same
HUE033007T2 (en) 2006-06-23 2017-11-28 Engeneic Molecular Delivery Pty Ltd Targeted drug, therapeutic nucleic acid and functional nucleic acid delivery to mammalian cells via intact killed bacterial cells
ATE485512T1 (de) * 2006-11-10 2010-11-15 Absorption Systems Group Llc Stabile zelllinien und verfahren zur beurteilung der aufnahme von chemikalien im magen-darm-trakt
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