HK1157635A1 - Metal-binding compounds and uses thereof - Google Patents
Metal-binding compounds and uses thereofInfo
- Publication number
- HK1157635A1 HK1157635A1 HK11111939.8A HK11111939A HK1157635A1 HK 1157635 A1 HK1157635 A1 HK 1157635A1 HK 11111939 A HK11111939 A HK 11111939A HK 1157635 A1 HK1157635 A1 HK 1157635A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- metal
- animal
- reducing
- binding compounds
- binding compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15740499P | 1999-10-01 | 1999-10-01 | |
US21107800P | 2000-06-13 | 2000-06-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1157635A1 true HK1157635A1 (en) | 2012-07-06 |
Family
ID=26854102
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11111939.8A HK1157635A1 (en) | 1999-10-01 | 2003-05-06 | Metal-binding compounds and uses thereof |
Country Status (12)
Country | Link |
---|---|
EP (2) | EP1220870B1 (ru) |
JP (1) | JP5349722B2 (ru) |
KR (6) | KR101312880B1 (ru) |
CN (2) | CN1390231A (ru) |
AT (1) | ATE553116T1 (ru) |
AU (1) | AU770999C (ru) |
BR (1) | BR0014389A (ru) |
CA (1) | CA2385551A1 (ru) |
HK (1) | HK1157635A1 (ru) |
IL (4) | IL148797A0 (ru) |
NZ (1) | NZ518266A (ru) |
WO (1) | WO2001025265A1 (ru) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020160417A1 (en) * | 2001-04-30 | 2002-10-31 | George Jackowski | Biopolymer marker indicative of disease state having a molecular weight of 1424 daltons |
US20030040602A1 (en) * | 2001-04-30 | 2003-02-27 | George Jackowski | Biopolymer marker indicative of disease state having a molecular weight of 1406 daltons |
JP2005517636A (ja) * | 2001-11-20 | 2005-06-16 | ディーエムアイ バイオサイエンシズ インコーポレイテッド | オーラル・ケアのための方法および製品 |
WO2004050023A2 (en) | 2002-11-27 | 2004-06-17 | Dmi Biosciences, Inc. | Treatment of diseases and conditions mediated by increased phosphorylation |
JP5265762B2 (ja) | 2008-05-13 | 2013-08-14 | ユニバーシティ・オブ・カンザス | 金属抽出ペプチド(map)タグおよび関連する方法 |
US9187735B2 (en) | 2012-06-01 | 2015-11-17 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
CN111925411B (zh) * | 2017-06-29 | 2022-04-08 | 安徽省农业科学院农产品加工研究所 | 一种含有Cys-Ser的高锌螯合活性锌螯合肽及其应用 |
CN113563418B (zh) * | 2021-06-22 | 2023-03-03 | 中国科学院化学研究所 | 一种原位响应ros的人工酶及其制备方法与应用 |
CN114437175B (zh) * | 2022-01-29 | 2023-09-29 | 山东第一医科大学第三附属医院(山东省医学科学院附属医院) | 一种肽探针及其应用和包含该肽探针的试剂盒 |
Family Cites Families (56)
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US3941763A (en) | 1975-03-28 | 1976-03-02 | American Home Products Corporation | PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates |
US4022888A (en) | 1975-09-09 | 1977-05-10 | Diagnostic Data, Inc. | Esterified orgotein |
US4461724A (en) | 1981-10-28 | 1984-07-24 | Nippon Zoki Pharmaceutical Co., Ltd. | Peptide compounds, a process for manufacturing them, pharmaceutical compositions containing them, and methods for treating ulcer and thrombus with them |
US4912118A (en) | 1983-09-23 | 1990-03-27 | National Research Development Corporation | Pharmaceutical compositions |
US4760051A (en) | 1985-01-24 | 1988-07-26 | Pickart Loren R | Use of GHL-Cu as a wound-healing and anti-inflammatory agent |
US5348943A (en) | 1985-02-08 | 1994-09-20 | Procyte Corporation | Cosmetic and skin treatment compositions |
US4767753A (en) | 1985-02-08 | 1988-08-30 | Procyte Corporation | Methods and compositions for preventing ulcers |
US4665054A (en) | 1985-02-08 | 1987-05-12 | Bioheal, Inc. | Chemical derivatives of GHL-Cu |
US5177061A (en) | 1985-02-08 | 1993-01-05 | Procyte Corporation | Method for stimulating hair growth using GHL-Cu complexes |
US4877770A (en) | 1985-02-08 | 1989-10-31 | Procyte Corporation | Chemical derivatives of GHL-Cu |
US5550183A (en) | 1985-02-08 | 1996-08-27 | Procyte Corporation | Metal-peptide compositions and methods for stimulating hair growth |
US5214032A (en) | 1985-02-08 | 1993-05-25 | Procyte Corporation | GHL-CU pharmaceutical compositions and compounds |
US4810693A (en) | 1985-02-08 | 1989-03-07 | Procyte Corporation | Method for inducing biological coverings in wounds |
US5120831A (en) | 1985-02-08 | 1992-06-09 | Procyte Corporation | Metal-peptide compositions |
US5422096A (en) | 1985-05-08 | 1995-06-06 | The General Hospital Corporation | Hydroxy-aryl metal chelates for diagnostic NMR imaging |
JPS62116565A (ja) * | 1985-11-15 | 1987-05-28 | Fujisawa Pharmaceut Co Ltd | 新規ペプチド |
GB8603537D0 (en) | 1986-02-13 | 1986-03-19 | Parker D | Conjugate compound |
EP0314755B1 (en) | 1987-05-11 | 1994-08-24 | Procyte Corporation | Use of derivatives of GHL-Cu for the manufacture of a medicament for stimulating hair growth |
ATE110954T1 (de) | 1988-01-29 | 1994-09-15 | Peter H Proctor | Haarwachstumanregung mit nitroxyd und anderen radikalen. |
US5101041A (en) | 1989-04-26 | 1992-03-31 | The Curators Of The University Of Missouri | Triamines and their derivatives as bifunctional chelating agents |
US5759515A (en) | 1989-08-09 | 1998-06-02 | Rhomed Incorporated | Polyvalent peptide pharmaceutical applications |
US5443816A (en) | 1990-08-08 | 1995-08-22 | Rhomed Incorporated | Peptide-metal ion pharmaceutical preparation and method |
US5460785A (en) | 1989-08-09 | 1995-10-24 | Rhomed Incorporated | Direct labeling of antibodies and other protein with metal ions |
DK0486622T3 (da) | 1989-08-09 | 1999-07-19 | Rhomed Inc | Direkte radiomærkning af antistoffer og andre proteiner med technetium eller rhenium |
US5145838A (en) | 1989-08-30 | 1992-09-08 | Procyte Corporation | Methods and compositions for healing ulcers |
US5023237A (en) | 1989-08-30 | 1991-06-11 | Procyte Corporation | Methods and compositions for healing ulcers |
US5059588A (en) | 1989-10-13 | 1991-10-22 | Procyte Corporation, Incorporated | Methods and compositions for healing bone using gly his lys: copper |
US5118665A (en) | 1990-02-09 | 1992-06-02 | Procyte Corporation | Anti-oxidative and anti-inflammatory metal:peptide complexes and uses thereof |
US5164367A (en) | 1990-03-26 | 1992-11-17 | Procyte Corporation | Method of using copper(ii) containing compounds to accelerate wound healing |
US5252559A (en) | 1991-08-20 | 1993-10-12 | The Procter & Gamble Company | His-Gly-Gly peptide and derivatives thereof for hair growth |
US5280038A (en) | 1992-03-13 | 1994-01-18 | Virginia Commonwealth University | Histidine as a protective agent in cardiac surgery and myocardial ischemic syndrome |
CA2094785A1 (en) | 1992-05-08 | 1993-11-09 | Jean Gariepy | Metal chelating peptide |
US5807535A (en) | 1992-07-31 | 1998-09-15 | Australian Nuclear Science & Technology Organisation | Metal complexes of hydroxyaryl containing aminocarboxylic acid chelating agents |
US5380747A (en) | 1992-10-30 | 1995-01-10 | Emory University | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases |
US5650134A (en) | 1993-01-12 | 1997-07-22 | Novartis Ag (Formerly Sandoz Ltd.) | Peptides |
US5464934A (en) | 1993-05-14 | 1995-11-07 | Mallinckrodt Medical, Inc. | Metal chelates as spacer compounds in biologically active peptides |
US5994339A (en) | 1993-10-15 | 1999-11-30 | University Of Alabama At Birmingham Research Foundation | Oxidant scavengers |
US5476939A (en) | 1993-12-30 | 1995-12-19 | Abbott Laboratories | Certain pyridyl and isoquinolyl carbinolamine derivatives |
JPH07316192A (ja) | 1994-05-27 | 1995-12-05 | Hoechst Japan Ltd | L−リシル−グリシル−l−ヒスチジンおよびこれを含有する創傷治療剤 |
US5538945A (en) | 1994-06-17 | 1996-07-23 | Procyte Corporation | Stimulation of hair growth by peptide copper complexes |
US5891418A (en) | 1995-06-07 | 1999-04-06 | Rhomed Incorporated | Peptide-metal ion pharmaceutical constructs and applications |
EP0955044B1 (en) | 1995-06-26 | 2005-11-16 | Chelator LLC | Method of inhibiting bacterial or fungal growth using a complexing agent |
US5637311A (en) | 1995-06-29 | 1997-06-10 | Procyte Corporation | Zinc(II) complexes and methods related thereto |
RU2106146C1 (ru) | 1995-07-17 | 1998-03-10 | Институт элементоорганических соединений РАН | Средство для подавления опухолевого роста |
US5786335A (en) | 1995-11-06 | 1998-07-28 | Warner-Lambert Company | Sulfhydryl containing peptides for treating vascular disease |
US5928955A (en) | 1996-03-22 | 1999-07-27 | California Institute Of Technology | Peptidyl fluorescent chemosensor for divalent zinc |
AU2958397A (en) | 1996-05-21 | 1997-12-09 | Novartis Ag | N,n'-di(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid derivatives |
GB9613182D0 (en) | 1996-06-24 | 1996-08-28 | Nycomed Imaging As | Method |
PL184070B1 (pl) | 1996-07-30 | 2002-08-30 | Politechnika Lodzka | Sposób wytwarzania peptydów zawierających a-hydroksymetyloserynę |
US5906996A (en) | 1996-08-21 | 1999-05-25 | Murphy; Michael A. | Tetramine treatment of neurological disorders |
US5922761A (en) | 1996-09-06 | 1999-07-13 | Medinox, Inc. | Methods for in vivo reduction of iron levels and compositions useful therefor |
US5739395A (en) | 1997-01-10 | 1998-04-14 | University Of Florida Research Foundation, Inc. | Method for synthesis of rhizoferrin |
GB9711093D0 (en) | 1997-05-29 | 1997-07-23 | British Tech Group | Novel orally active iron (III) chelators |
CA2319255C (en) | 1998-02-04 | 2010-01-26 | University Of Florida Research Foundation, Inc. | Pharmaceuticals comprising n,n'-bis(2- hydroxybenzyl) ethylenediamine-n, n'-diacetic acid for iron chelating therapy |
DE19819843A1 (de) | 1998-05-05 | 1999-11-11 | Biotechnolog Forschung Gmbh | Metallchelat bindende Peptide |
AU755564B2 (en) | 1998-06-20 | 2002-12-12 | Washington University | Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy |
-
2000
- 2000-09-29 KR KR1020117031645A patent/KR101312880B1/ko not_active IP Right Cessation
- 2000-09-29 KR KR1020117031646A patent/KR101353140B1/ko not_active IP Right Cessation
- 2000-09-29 AU AU77407/00A patent/AU770999C/en not_active Ceased
- 2000-09-29 KR KR1020097012559A patent/KR101062041B1/ko not_active IP Right Cessation
- 2000-09-29 KR KR1020107008232A patent/KR20100075503A/ko not_active Application Discontinuation
- 2000-09-29 CA CA002385551A patent/CA2385551A1/en not_active Abandoned
- 2000-09-29 EP EP00967163A patent/EP1220870B1/en not_active Expired - Lifetime
- 2000-09-29 CN CN00815718A patent/CN1390231A/zh active Pending
- 2000-09-29 CN CN2010105807752A patent/CN102038932B/zh not_active Expired - Fee Related
- 2000-09-29 EP EP10183238A patent/EP2327713A1/en not_active Withdrawn
- 2000-09-29 KR KR1020027004228A patent/KR20020057966A/ko not_active Application Discontinuation
- 2000-09-29 NZ NZ518266A patent/NZ518266A/en not_active IP Right Cessation
- 2000-09-29 AT AT00967163T patent/ATE553116T1/de active
- 2000-09-29 JP JP2001528205A patent/JP5349722B2/ja not_active Expired - Fee Related
- 2000-09-29 IL IL14879700A patent/IL148797A0/xx unknown
- 2000-09-29 BR BR0014389-8A patent/BR0014389A/pt not_active IP Right Cessation
- 2000-09-29 WO PCT/US2000/026952 patent/WO2001025265A1/en active IP Right Grant
- 2000-09-29 KR KR1020117006608A patent/KR20110049875A/ko not_active Application Discontinuation
-
2002
- 2002-03-20 IL IL148797A patent/IL148797A/en not_active IP Right Cessation
-
2003
- 2003-05-06 HK HK11111939.8A patent/HK1157635A1/xx not_active IP Right Cessation
-
2009
- 2009-12-17 IL IL202812A patent/IL202812A0/en unknown
-
2010
- 2010-09-01 IL IL207923A patent/IL207923A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP2327713A1 (en) | 2011-06-01 |
EP1220870A1 (en) | 2002-07-10 |
WO2001025265A1 (en) | 2001-04-12 |
KR20110049875A (ko) | 2011-05-12 |
KR20120024890A (ko) | 2012-03-14 |
KR20090086437A (ko) | 2009-08-12 |
IL148797A (en) | 2010-12-30 |
KR101062041B1 (ko) | 2011-09-02 |
BR0014389A (pt) | 2002-10-29 |
AU770999B2 (en) | 2004-03-11 |
CN102038932B (zh) | 2013-11-06 |
KR101353140B1 (ko) | 2014-01-20 |
CN1390231A (zh) | 2003-01-08 |
EP1220870B1 (en) | 2012-04-11 |
KR20120023147A (ko) | 2012-03-12 |
KR20020057966A (ko) | 2002-07-12 |
CN102038932A (zh) | 2011-05-04 |
JP5349722B2 (ja) | 2013-11-20 |
ATE553116T1 (de) | 2012-04-15 |
CA2385551A1 (en) | 2001-04-12 |
KR101312880B1 (ko) | 2013-09-30 |
IL207923A0 (en) | 2011-07-31 |
IL202812A0 (en) | 2011-07-31 |
JP2003528814A (ja) | 2003-09-30 |
EP1220870A4 (en) | 2004-04-07 |
AU7740700A (en) | 2001-05-10 |
IL148797A0 (en) | 2002-09-12 |
AU770999C (en) | 2005-04-21 |
NZ518266A (en) | 2005-01-28 |
KR20100075503A (ko) | 2010-07-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20170929 |