HK1149709A1 - Use of mva to treat prostate cancer mva - Google Patents
Use of mva to treat prostate cancer mvaInfo
- Publication number
- HK1149709A1 HK1149709A1 HK11103921.5A HK11103921A HK1149709A1 HK 1149709 A1 HK1149709 A1 HK 1149709A1 HK 11103921 A HK11103921 A HK 11103921A HK 1149709 A1 HK1149709 A1 HK 1149709A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- mva
- prostate cancer
- treat prostate
- recombinant mva
- mva viruses
- Prior art date
Links
- 206010060862 Prostate cancer Diseases 0.000 title 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 230000005867 T cell response Effects 0.000 abstract 1
- 229940123237 Taxane Drugs 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001193—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; PAP or PSGR
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001193—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; PAP or PSGR
- A61K39/001194—Prostate specific antigen [PSA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/023—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a poxvirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/04—Uses of viruses as vector in vivo
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Developmental Biology & Embryology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US96089307P | 2007-10-18 | 2007-10-18 | |
PCT/US2008/080229 WO2009052328A1 (en) | 2007-10-18 | 2008-10-16 | Use of mva to treat prostate cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1149709A1 true HK1149709A1 (en) | 2011-10-14 |
Family
ID=40342626
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11103921.5A HK1149709A1 (en) | 2007-10-18 | 2011-04-19 | Use of mva to treat prostate cancer mva |
Country Status (14)
Country | Link |
---|---|
US (2) | US7867483B2 (ja) |
EP (1) | EP2207564B1 (ja) |
JP (1) | JP5669581B2 (ja) |
KR (2) | KR20160065985A (ja) |
CN (1) | CN101888853B (ja) |
AU (1) | AU2008312444B2 (ja) |
CA (1) | CA2702586C (ja) |
DK (1) | DK2207564T3 (ja) |
ES (1) | ES2608604T3 (ja) |
HK (1) | HK1149709A1 (ja) |
IL (1) | IL204541A (ja) |
NZ (2) | NZ601827A (ja) |
RU (1) | RU2499606C2 (ja) |
WO (1) | WO2009052328A1 (ja) |
Families Citing this family (36)
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US6136311A (en) | 1996-05-06 | 2000-10-24 | Cornell Research Foundation, Inc. | Treatment and diagnosis of cancer |
EP1598425A1 (en) * | 2000-11-23 | 2005-11-23 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant |
US8940871B2 (en) | 2006-03-20 | 2015-01-27 | The Regents Of The University Of California | Engineered anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting |
JP6126773B2 (ja) | 2007-09-04 | 2017-05-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 癌のターゲッティングおよび検出のための高親和性抗前立腺幹細胞抗原(psca)抗体 |
EP2740490A1 (en) * | 2007-10-03 | 2014-06-11 | Cornell University | Treatment of proliferative disorders using antibodies to PSMA |
KR20160065985A (ko) * | 2007-10-18 | 2016-06-09 | 버베리안 노딕 에이/에스 | 전립선 암 치료를 위한 mva의 용도 |
US20100069616A1 (en) * | 2008-08-06 | 2010-03-18 | The Regents Of The University Of California | Engineered antibody-nanoparticle conjugates |
ES2712732T3 (es) * | 2009-02-17 | 2019-05-14 | Cornell Res Foundation Inc | Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico |
GB2484058A (en) * | 2009-12-01 | 2012-04-04 | Uni Konstanz | Prostate cancer DNA vaccine |
EP2506876B1 (en) | 2009-12-02 | 2016-10-12 | Imaginab, Inc. | J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use |
EP2833150A4 (en) | 2012-03-30 | 2016-03-23 | Univ Kyoto | URINBIOMARKER FOR USE IN A TEST ON PROSTATE CANCER |
BR112016008806A2 (pt) | 2013-11-01 | 2017-10-03 | Pfizer | Vetores para expressão de antígenos associados à próstata |
BR112017005245A2 (pt) | 2014-09-19 | 2017-12-12 | Regeneron Pharma | animal não humano geneticamente modificado, métodos para produzir célula t, hibridoma de célula t, um ácido nucleico, um anticorpo específico, uma célula humana, um animal não humano geneticamente modificado e para induzir uma resposta imunológica, célula, hibridoma de célula t, ácido nucleico, anticorpo específico, receptor de antígeno quimérico, embrião não humano, locus de um receptor de antígeno quimérico, e, composição de ácidos nucleicos. |
WO2016144564A2 (en) | 2015-02-25 | 2016-09-15 | Memorial Sloan-Kettering Cancer Center | Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors |
WO2016168862A1 (en) | 2015-04-17 | 2016-10-20 | Memorial Sloan-Kettering Cancer Center | Use of mva or mvadeltae3l as immunotherapeutic agents against solid tumors |
EP4137158A1 (en) | 2015-08-07 | 2023-02-22 | Imaginab, Inc. | Antigen binding constructs to target molecules |
FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
GB201520570D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520568D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd | Peptides |
GB201520550D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
US11000578B2 (en) * | 2016-02-12 | 2021-05-11 | Madison Vaccines Inc. | Treatment of prostate cancer with pap vaccine and PD-1 inhibitor co-therapy |
MX2018010204A (es) | 2016-02-25 | 2019-05-06 | Memorial Sloan Kettering Cancer Center | Virus de la vaccinia atenuada competentes para replicacion con la supresion de timidina quinasa con y sin la expresion del flt3l o gm-csf humanos para inmunoterapia del cancer. |
CN109152827B (zh) | 2016-02-25 | 2023-07-21 | 纪念斯隆凯特琳癌症中心 | 重组mva或表达人flt3l的mvaδe3l及其作为抗固体肿瘤的免疫治疗剂的用途 |
US10703755B2 (en) * | 2016-04-26 | 2020-07-07 | Sumitomo Dainippon Pharma Co., Ltd. | Substituted purine derivative |
CN116458475A (zh) | 2016-06-03 | 2023-07-21 | 瑞泽恩制药公司 | 表达外源末端脱氧核苷酸转移酶的非人动物 |
AU2017274540B2 (en) * | 2016-06-03 | 2020-04-16 | Etubics Corporation | Compositions and methods for tumor vaccination using prostate cancer-associated antigens |
CN106084027A (zh) * | 2016-06-24 | 2016-11-09 | 安徽未名细胞治疗有限公司 | 特异性肿瘤抗原EphA2的CTL识别表位肽及其应用 |
CN106119231A (zh) * | 2016-06-24 | 2016-11-16 | 安徽未名细胞治疗有限公司 | 一种肿瘤抗原psa的ctl识别表位肽及其应用 |
WO2018147960A1 (en) | 2017-02-08 | 2018-08-16 | Imaginab, Inc. | Extension sequences for diabodies |
CN111107872A (zh) | 2017-05-12 | 2020-05-05 | 纪念斯隆-凯特林癌症中心 | 有用于癌症免疫疗法的牛痘病毒突变体 |
US10925947B2 (en) * | 2018-06-29 | 2021-02-23 | Immatics Biotechnologies Gmbh | A*03 restricted peptides for use in immunotherapy against cancers and related methods |
TW202043256A (zh) | 2019-01-10 | 2020-12-01 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
JP2022536122A (ja) * | 2019-06-07 | 2022-08-12 | オレゴン ヘルス アンド サイエンス ユニバーシティ | 腫瘍関連抗原特異的t細胞応答 |
WO2021099906A1 (en) | 2019-11-18 | 2021-05-27 | Janssen Biotech, Inc. | Vaccines based on mutant calr and jak2 and their uses |
US20210315986A1 (en) * | 2020-04-13 | 2021-10-14 | Janssen Biotech, Inc. | Psma and steap1 vaccines and their uses |
US20230029453A1 (en) * | 2020-07-06 | 2023-02-02 | Janssen Biotech, Inc. | Prostate Neoantigens And Their Uses |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
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EP0596032B2 (en) * | 1991-07-25 | 2004-04-07 | Idec Pharmaceuticals Corporation | Induction of cytotoxic t-lymphocyte responses |
US5925362A (en) * | 1993-08-11 | 1999-07-20 | Jenner Technologies | Method to elicit an antitumor response with human prostate-specific antigen |
US6045802A (en) * | 1994-10-03 | 2000-04-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule |
US6165460A (en) * | 1995-07-10 | 2000-12-26 | Therion Biologics Corporation | Generation of immune responses to prostate-specific antigen (PSA) |
US5882864A (en) * | 1995-07-31 | 1999-03-16 | Urocor Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate disease |
AU6897998A (en) | 1997-04-11 | 1998-11-11 | Dendreon Corporation | Composition and method for inducing an immune response against tumour-rela ted antigens |
HUP0103976A3 (en) | 1998-10-05 | 2008-04-28 | Pharmexa As | Novel methods for therapeutic vaccination |
CA2354024C (en) * | 1998-12-09 | 2009-12-22 | Jeffrey Schlom | A recombinant vector expressing multiple costimulatory molecules and uses thereof |
EP1598425A1 (en) | 2000-11-23 | 2005-11-23 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant |
WO2003073828A2 (en) * | 2002-03-01 | 2003-09-12 | Applied Immune Technologies | Immunotherapy for prostate cancer using recombinant bacille calmette-guerin expressing prostate specific antigens |
CN102703393A (zh) * | 2002-05-16 | 2012-10-03 | 巴法里安诺迪克有限公司 | 表达插入痘病毒基因组中的同源基因的重组痘病毒 |
EP1660664A4 (en) * | 2003-08-21 | 2008-02-13 | Virax Dev Pty Ltd | POXVIRUS VECTOR ENCODING SPECIFIC PROSTATE ANTIGENS FOR THE TREATMENT OF PROSTATE CANCER |
BRPI0401465A (pt) | 2004-04-20 | 2006-02-21 | Embria Informatica Ltda | sistema para administrar interações entre usuários e aplicações de software em um ambiente web |
KR20160065985A (ko) | 2007-10-18 | 2016-06-09 | 버베리안 노딕 에이/에스 | 전립선 암 치료를 위한 mva의 용도 |
-
2008
- 2008-10-16 KR KR1020167013629A patent/KR20160065985A/ko not_active Application Discontinuation
- 2008-10-16 CN CN2008801193517A patent/CN101888853B/zh not_active Expired - Fee Related
- 2008-10-16 CA CA2702586A patent/CA2702586C/en not_active Expired - Fee Related
- 2008-10-16 RU RU2010115220/15A patent/RU2499606C2/ru not_active IP Right Cessation
- 2008-10-16 EP EP08839145.3A patent/EP2207564B1/en not_active Not-in-force
- 2008-10-16 NZ NZ601827A patent/NZ601827A/en not_active IP Right Cessation
- 2008-10-16 US US12/253,094 patent/US7867483B2/en not_active Expired - Fee Related
- 2008-10-16 KR KR1020107010873A patent/KR101648087B1/ko active IP Right Grant
- 2008-10-16 JP JP2010530124A patent/JP5669581B2/ja not_active Expired - Fee Related
- 2008-10-16 WO PCT/US2008/080229 patent/WO2009052328A1/en active Application Filing
- 2008-10-16 AU AU2008312444A patent/AU2008312444B2/en not_active Ceased
- 2008-10-16 NZ NZ584042A patent/NZ584042A/xx not_active IP Right Cessation
- 2008-10-16 ES ES08839145.3T patent/ES2608604T3/es active Active
- 2008-10-16 DK DK08839145.3T patent/DK2207564T3/en active
-
2010
- 2010-03-16 IL IL204541A patent/IL204541A/en active IP Right Grant
- 2010-08-30 US US12/871,017 patent/US8377688B2/en not_active Expired - Fee Related
-
2011
- 2011-04-19 HK HK11103921.5A patent/HK1149709A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NZ601827A (en) | 2014-01-31 |
US8377688B2 (en) | 2013-02-19 |
NZ584042A (en) | 2012-09-28 |
CA2702586A1 (en) | 2009-04-23 |
AU2008312444B2 (en) | 2014-02-06 |
US7867483B2 (en) | 2011-01-11 |
EP2207564A1 (en) | 2010-07-21 |
US20110008386A1 (en) | 2011-01-13 |
IL204541A0 (en) | 2010-11-30 |
RU2499606C2 (ru) | 2013-11-27 |
CN101888853A (zh) | 2010-11-17 |
JP2011500718A (ja) | 2011-01-06 |
JP5669581B2 (ja) | 2015-02-12 |
KR101648087B1 (ko) | 2016-08-17 |
US20090104225A1 (en) | 2009-04-23 |
DK2207564T3 (en) | 2017-01-16 |
KR20100109545A (ko) | 2010-10-08 |
KR20160065985A (ko) | 2016-06-09 |
CA2702586C (en) | 2017-08-01 |
WO2009052328A1 (en) | 2009-04-23 |
ES2608604T3 (es) | 2017-04-12 |
EP2207564B1 (en) | 2016-10-05 |
WO2009052328A8 (en) | 2009-07-02 |
CN101888853B (zh) | 2013-03-13 |
AU2008312444A1 (en) | 2009-04-23 |
IL204541A (en) | 2015-02-26 |
RU2010115220A (ru) | 2011-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20191010 |