HK1146281A1 - 三取代的 -三唑化合物 - Google Patents

三取代的 -三唑化合物

Info

Publication number
HK1146281A1
HK1146281A1 HK11100474.2A HK11100474A HK1146281A1 HK 1146281 A1 HK1146281 A1 HK 1146281A1 HK 11100474 A HK11100474 A HK 11100474A HK 1146281 A1 HK1146281 A1 HK 1146281A1
Authority
HK
Hong Kong
Prior art keywords
trisubstituted
triazoles
Prior art date
Application number
HK11100474.2A
Other languages
English (en)
Inventor
Johannes Wilhelmus John F Thuring
Theodorus Dinklo
Anne Simone Josephine Lesage
Bruyn Marcel Frans Leopold De
Wei Zhuang
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1146281A1 publication Critical patent/HK1146281A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK11100474.2A 2007-10-18 2011-01-18 三取代的 -三唑化合物 HK1146281A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07118825 2007-10-18
PCT/EP2008/063845 WO2009050186A1 (en) 2007-10-18 2008-10-15 Trisubstituted 1,2,4-triazoles

Publications (1)

Publication Number Publication Date
HK1146281A1 true HK1146281A1 (zh) 2011-05-27

Family

ID=38754647

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11100474.2A HK1146281A1 (zh) 2007-10-18 2011-01-18 三取代的 -三唑化合物

Country Status (17)

Country Link
US (1) US8440701B2 (zh)
EP (1) EP2212309B1 (zh)
JP (1) JP2011500625A (zh)
CN (1) CN101827836B (zh)
AR (1) AR070661A1 (zh)
AU (1) AU2008313776B2 (zh)
CA (1) CA2697974C (zh)
CL (1) CL2008003066A1 (zh)
ES (1) ES2424023T3 (zh)
HK (1) HK1146281A1 (zh)
IL (1) IL205101A (zh)
MX (1) MX2010004177A (zh)
PA (1) PA8799801A1 (zh)
PE (1) PE20090877A1 (zh)
RU (1) RU2474579C2 (zh)
TW (1) TWI438198B (zh)
WO (1) WO2009050186A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2508524A3 (en) * 2006-10-19 2012-10-24 Takeda Pharmaceutical Company Limited Indole compound
JO2784B1 (en) * 2007-10-18 2014-03-15 شركة جانسين فارماسوتيكا ان. في 5,3,1 - Triazole substitute derivative
MY152486A (en) * 2008-03-19 2014-10-15 Janssen Pharmaceutica Nv Trisubstituted 1,2,4 - triazoles as nicotinic acetylcholine receptor modulators
CN102015655A (zh) * 2008-05-09 2011-04-13 詹森药业有限公司 作为乙酰胆碱受体调节剂的三取代吡唑类
JP5841617B2 (ja) 2011-02-25 2016-01-13 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプＪａｎｓｓｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａ Ｎａａｍｌｏｚｅ Ｖｅｎｎｏｏｔｓｃｈａｐ アルファ７ｎＡＣｈＲのアロステリック調節因子としての（ピリジン−４−イル）ベンジルアミド

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795907A (fr) * 1972-02-25 1973-06-18 Luso Farmaco Inst 2-amino-4-arylthiazoles 5-substitues et leur preparation
DE3773746D1 (en) 1986-05-07 1991-11-21 Fisons Plc Pyrazole.
JPS6339868A (ja) 1986-08-04 1988-02-20 Otsuka Pharmaceut Factory Inc ジ低級アルキルフエノ−ル誘導体
US4761422A (en) 1986-11-20 1988-08-02 Lusofarmaco Istituto Lusofarmaco D'italia Spa (2-amino-4-aryl-thiazole-5-yl)ethanols and their derivatives having diuretic activity and methods for preparing the same
JPH10504542A (ja) 1994-07-27 1998-05-06 ジー．ディー．サール アンド カンパニー 炎症処置用の置換チアゾール化合物
JPH10507205A (ja) 1995-08-02 1998-07-14 ホータ．ウリアッヒ イ シイア．エセ．アー． 抗真菌活性を有する新規カルボンアミド
FR2754258B1 (fr) 1996-10-08 1998-12-31 Sanofi Sa Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
US6187797B1 (en) * 1996-12-23 2001-02-13 Dupont Pharmaceuticals Company Phenyl-isoxazoles as factor XA Inhibitors
JP2001506271A (ja) 1996-12-23 2001-05-15 デュポン ファーマシューティカルズ カンパニー Ｘａ因子阻害剤としての酸素またはイオウを含む複素環式芳香族化合物
JPH11193281A (ja) 1997-10-27 1999-07-21 Takeda Chem Ind Ltd アデノシンａ３受容体拮抗剤およびチアゾール化合物
FR2792314B1 (fr) 1999-04-15 2001-06-01 Adir Nouveaux composes aminotriazoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ATE257827T1 (de) 1999-07-21 2004-01-15 Hoffmann La Roche Triazolderivate
CA2381215A1 (en) 1999-08-06 2001-02-15 Takeda Chemical Industries, Ltd. P38map kinase inhibitors
FR2802530B1 (fr) 1999-12-17 2002-02-22 Sanofi Synthelabo Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant
AU3740101A (en) 2000-03-01 2001-09-12 Janssen Pharmaceutica Nv 2,4-disubstituted thiazolyl derivatives
WO2001074793A2 (en) 2000-04-03 2001-10-11 3-Dimensional Pharmaceuticals, Inc. Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1
AU2001296255B2 (en) 2000-09-21 2005-07-28 Bristol-Myers Squibb Company Substituted azole derivatives as inhibitors of corticotropin releasing factor
GB0028383D0 (en) 2000-11-21 2001-01-03 Novartis Ag Organic compounds
BR0116792A (pt) 2000-12-22 2004-02-17 Ortho Mcneil Pharm Inc Derivados de diamina de triazol substituìdos como inibidores de quinase
KR101034489B1 (ko) 2001-08-13 2011-05-17 얀센 파마슈티카 엔.브이. 2-아미노-4,5-삼치환 티아졸릴 유도체
WO2003039451A2 (en) * 2001-11-08 2003-05-15 Fujisawa Pharmaceutical Co., Ltd. Thiazole pyridazinones as adenosine antagonists
CA2474322A1 (en) 2002-01-25 2003-07-31 Kylix Pharmaceuticals B.V. 4(hetero-) aryl substituted (thia-/oxa-/pyra) zoles for inhibition of tie-2
US7300933B2 (en) * 2002-05-07 2007-11-27 Neurosearch A/S Diazabicyclic biaryl derivatives
CL2003002353A1 (es) * 2002-11-15 2005-02-04 Vertex Pharma Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condic
WO2004096225A2 (en) 2003-04-28 2004-11-11 Ab Science Use of tyrosine kinase inhibitors for treating cerebral ischemia
CN102584813B (zh) 2003-05-14 2016-07-06 Ngc药物公司 化合物及其在调节淀粉样蛋白β中的用途
WO2005000298A2 (en) * 2003-06-03 2005-01-06 Novartis Ag 5-membered heterocycle-based p-38 inhibitors
CA2532505A1 (en) 2003-07-24 2005-02-10 Pharmagene Laboratories Limited 5-ht2b receptor antagonists
FR2862647B1 (fr) 2003-11-25 2008-07-04 Aventis Pharma Sa Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant
GB0401336D0 (en) 2004-01-21 2004-02-25 Novartis Ag Organic compounds
ES2359007T3 (es) * 2004-09-17 2011-05-17 Vertex Pharmaceuticals Incorporated Compuestos de diaminotriazol útiles como inhibidores de proteínas quinasas.
CN101072556A (zh) 2004-10-21 2007-11-14 沃泰克斯药物股份有限公司 可用作蛋白激酶抑制剂的三唑
WO2006064375A2 (en) 2004-12-16 2006-06-22 Ab Science Aminoaryl substituted five-membered ring heterocyclic compounds for the treatment of diseases
AU2006206611A1 (en) * 2005-01-19 2006-07-27 Bristol-Myers Squibb Company 2-phenoxy-N- (1, 3 , 4-thiadizol-2-yl) pyridin-3-amine derivatives and related compounds as P2Y1 receptor inhibitors for the treatment of thromboembolic disorders
AU2006290814B2 (en) * 2005-09-13 2012-06-07 Janssen Pharmaceutica N.V. 2-aniline-4-aryl substituted thiazole derivatives
JO3019B1 (ar) * 2006-04-19 2016-09-05 Janssen Pharmaceutica Nv ثلاثي مستبدل 4،2،1-ثلاثي زولات
JO2784B1 (en) * 2007-10-18 2014-03-15 شركة جانسين فارماسوتيكا ان. في 5,3,1 - Triazole substitute derivative
MY152486A (en) * 2008-03-19 2014-10-15 Janssen Pharmaceutica Nv Trisubstituted 1,2,4 - triazoles as nicotinic acetylcholine receptor modulators
AU2009237649B2 (en) 2008-04-17 2012-07-26 Proximagen Limited Indole modulators of the alpha 7 nicotinic acetylcholine receptor
CN102015655A (zh) * 2008-05-09 2011-04-13 詹森药业有限公司 作为乙酰胆碱受体调节剂的三取代吡唑类
BR112012005960A2 (pt) * 2009-09-17 2016-03-15 Janssen Pharmaceutica Nv n-fenil-1-(4-piridinil)-1h-pirazol-3-aminas substituídas
JO3078B1 (ar) * 2009-11-27 2017-03-15 Janssen Pharmaceutica Nv مورفولينوثيازولات بصفتها منظمات الوستيرية نوع الفا 7 موجبة
JP5841617B2 (ja) 2011-02-25 2016-01-13 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプＪａｎｓｓｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａ Ｎａａｍｌｏｚｅ Ｖｅｎｎｏｏｔｓｃｈａｐ アルファ７ｎＡＣｈＲのアロステリック調節因子としての（ピリジン−４−イル）ベンジルアミド

Also Published As

Publication number Publication date
IL205101A (en) 2015-02-26
EP2212309A1 (en) 2010-08-04
TWI438198B (zh) 2014-05-21
CN101827836A (zh) 2010-09-08
MX2010004177A (es) 2010-05-03
PA8799801A1 (es) 2009-05-15
RU2474579C2 (ru) 2013-02-10
WO2009050186A1 (en) 2009-04-23
JP2011500625A (ja) 2011-01-06
US20100216846A1 (en) 2010-08-26
RU2010119459A (ru) 2011-11-27
TW200934769A (en) 2009-08-16
CN101827836B (zh) 2014-02-19
CL2008003066A1 (es) 2009-10-16
ES2424023T3 (es) 2013-09-26
AU2008313776A1 (en) 2009-04-23
CA2697974A1 (en) 2009-04-23
PE20090877A1 (es) 2009-07-02
CA2697974C (en) 2015-06-30
AR070661A1 (es) 2010-04-28
IL205101A0 (en) 2010-11-30
EP2212309B1 (en) 2013-06-19
AU2008313776B2 (en) 2013-12-05
US8440701B2 (en) 2013-05-14

Similar Documents

Publication Publication Date Title
IL194744A0 (en) Trisubstituted 1,2,4-triazoles
EP2361902A4 (en) 4,6-DIAMINONICOTINSÄUREAMIDVERBINDUNG
IL225694A0 (en) Compounds 6,5- dihydro-h1-pyridine-2-one
SI2356123T1 (sl) Piro-5,6-dihidro-4h-2,3,5,10b-tetraaza-benzo(e)azuleni
HK1110857A1 (en) Heterocyclylamide-substituted imidazoles
HK1146281A1 (zh) 三取代的 -三唑化合物
EP2202231A4 (en) 2,3-DIHYDROIMINOISOINDOLE DERIVATIVE
GB0702228D0 (en) The cosy-cushion
GB0707146D0 (en) The bealyboard
HK1161684A1 (zh) -二氫 - -吡啶- -酮化合物
IL194972A0 (en) 2-alkoxy-3,4,5-trihydroxy-alkylamide-
GB0719111D0 (en) T.m.2
GB0711387D0 (en) The fincubator
GB0701309D0 (en) The easi-strutt
GB0720590D0 (en) T.m.3
GB0723127D0 (en) T.m.5
PL383280A1 (pl) Układ do sterowania urządzeń połączonych w sieć, sposób sterowania poprzez otwartą magistralę typu Feldbus urządzeń połączonych w sieć za pomocą magistrali oraz łącznik sterowany przez układ
GB0808811D0 (en) Algabe 2.1
PL384214A1 (pl) Drzwi, zwłaszcza do więzień i aresztów
AU2007047V (en) PP 031 Scaevola aemula
GB0702708D0 (en) IP.Access 2
GB0702705D0 (en) IP.Access 1
GB0813815D0 (en) Corcost Pre 1001,10
GB0703554D0 (en) The allotpot
GB0704798D0 (en) The dagice

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20221017