HK1146056A1 - Substituted n-phenyl-bipyrrolidine ureas and therapeutic use thereof - Google Patents
Substituted n-phenyl-bipyrrolidine ureas and therapeutic use thereofInfo
- Publication number
- HK1146056A1 HK1146056A1 HK11100257.5A HK11100257A HK1146056A1 HK 1146056 A1 HK1146056 A1 HK 1146056A1 HK 11100257 A HK11100257 A HK 11100257A HK 1146056 A1 HK1146056 A1 HK 1146056A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- phenyl
- substituted
- therapeutic use
- bipyrrolidine
- ureas
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98060607P | 2007-10-17 | 2007-10-17 | |
PCT/US2008/079763 WO2009052068A1 (fr) | 2007-10-17 | 2008-10-14 | Urées de n-phényl-bipyrrolidine substituées et leur utilisation thérapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1146056A1 true HK1146056A1 (en) | 2011-05-13 |
Family
ID=40248052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11100257.5A HK1146056A1 (en) | 2007-10-17 | 2011-01-12 | Substituted n-phenyl-bipyrrolidine ureas and therapeutic use thereof |
Country Status (25)
Country | Link |
---|---|
US (1) | US8222290B2 (fr) |
EP (1) | EP2215058B1 (fr) |
JP (1) | JP5380455B2 (fr) |
KR (1) | KR20100082349A (fr) |
CN (1) | CN101903341B (fr) |
AT (1) | ATE534625T1 (fr) |
AU (1) | AU2008312641A1 (fr) |
CA (1) | CA2702933C (fr) |
CY (1) | CY1112391T1 (fr) |
DK (1) | DK2215058T3 (fr) |
ES (1) | ES2378011T3 (fr) |
HK (1) | HK1146056A1 (fr) |
HR (1) | HRP20120166T1 (fr) |
IL (1) | IL205002A0 (fr) |
MA (1) | MA31889B1 (fr) |
MX (1) | MX2010003948A (fr) |
MY (1) | MY148807A (fr) |
NZ (1) | NZ584692A (fr) |
PL (1) | PL2215058T3 (fr) |
PT (1) | PT2215058E (fr) |
RS (1) | RS52221B (fr) |
RU (1) | RU2478094C2 (fr) |
SI (1) | SI2215058T1 (fr) |
WO (1) | WO2009052068A1 (fr) |
ZA (1) | ZA201002114B (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2010003949A (es) * | 2007-10-17 | 2010-04-30 | Sanofi Aventis | N-fenil-bipirrolidina carboxamidas sustituidas y uso terapeutico de las mismas. |
WO2009052065A1 (fr) * | 2007-10-17 | 2009-04-23 | Sanofi-Aventis | Carboxamides de n-phényl-bipyrrolidine substitués et leur utilisation thérapeutique |
BRPI0818766A2 (pt) * | 2007-10-17 | 2015-04-14 | Sanofi Aventis | N-fenil-pirrolidinilmetilpirrolidinamidas substituídas e uso terapêutico das mesmas |
CN101983181B (zh) | 2008-06-13 | 2015-10-14 | Lg化学株式会社 | 加热件及其制备方法 |
US10412788B2 (en) | 2008-06-13 | 2019-09-10 | Lg Chem, Ltd. | Heating element and manufacturing method thereof |
KR20090129927A (ko) | 2008-06-13 | 2009-12-17 | 주식회사 엘지화학 | 발열체 및 이의 제조방법 |
EP2569304A1 (fr) | 2010-05-11 | 2013-03-20 | Sanofi | Bipyrrolidines n-hétéroaryl spirolactame substituées, procédé de préparation et usage thérapeutique associés |
WO2011143161A1 (fr) * | 2010-05-11 | 2011-11-17 | Sanofi | Dérivés de n-hétérocycloalkyl-bipyrrolidinylphénylamide substitués, préparation et utilisation thérapeutique de ceux-ci |
AR081384A1 (es) * | 2010-05-11 | 2012-08-29 | Sanofi Aventis | N- fenil espirolactama bipirrolidinas sustituidas, preparacion y uso terapeutico de las mismas |
WO2011143145A1 (fr) | 2010-05-11 | 2011-11-17 | Sanofi | Dérivés n-alkyl et n-acyl tétrahydro-isoquinoline substitués, procédé de préparation et application thérapeutiques associés |
WO2011143155A1 (fr) | 2010-05-11 | 2011-11-17 | Sanofi | Dérivés de n-hétéroaryl tétrahydro-isoquinolines substituées, procédé de préparation et usage thérapeutique associés |
WO2011143162A1 (fr) * | 2010-05-11 | 2011-11-17 | Sanofi | Carboxamides de n-hétéroaryl-bipyrrolidine substitués, leur préparation et leur utilisation thérapeutique |
AR083718A1 (es) | 2010-05-11 | 2013-03-20 | Sanofi Aventis | Fenil cicloalquil pirrolidina (piperidina) espirolactamas y amidas sustituidas, preparacion y uso terapeutico de las mismas |
TW201238950A (en) | 2010-11-15 | 2012-10-01 | Abbott Lab | NAMPT and rock inhibitors |
AP3340A (en) * | 2011-02-23 | 2015-07-31 | Suven Life Science Ltd | Novel compounds as histamine H3 receptor ligands |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20020507A1 (es) * | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
WO2004037257A1 (fr) * | 2002-10-23 | 2004-05-06 | Janssen Pharmaceutica, N.V. | Phenylpiperidines et phenylpyrrolidines utilisees comme modulateurs du recepteur h3 de l'histamine |
DE10306250A1 (de) * | 2003-02-14 | 2004-09-09 | Aventis Pharma Deutschland Gmbh | Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US7223788B2 (en) * | 2003-02-14 | 2007-05-29 | Sanofi-Aventis Deutschland Gmbh | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments |
BRPI0608523A2 (pt) | 2005-03-17 | 2010-11-16 | Lilly Co Eli | composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, métodos para inibir receptor de histamina h3 em um mamìfero, para tratar ou prevenir um distúrbio do sistema nervoso, para tratar ou prevenir obesidade e para tratar ou prevenir um distúrbio ou doença, e, uso de um composto ou um sal do mesmo |
CN101151244B (zh) * | 2005-04-01 | 2014-09-03 | 伊莱利利公司 | 组胺h3受体活性剂、制备和治疗用途 |
ATE523488T1 (de) * | 2005-07-01 | 2011-09-15 | Lilly Co Eli | Histamin-h3-rezeptor-mittel, deren herstellung und therapeutische verwendung |
US7943605B2 (en) * | 2005-10-27 | 2011-05-17 | Ucb Pharma S.A. | Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses |
WO2009052065A1 (fr) | 2007-10-17 | 2009-04-23 | Sanofi-Aventis | Carboxamides de n-phényl-bipyrrolidine substitués et leur utilisation thérapeutique |
MX2010003949A (es) | 2007-10-17 | 2010-04-30 | Sanofi Aventis | N-fenil-bipirrolidina carboxamidas sustituidas y uso terapeutico de las mismas. |
BRPI0818766A2 (pt) | 2007-10-17 | 2015-04-14 | Sanofi Aventis | N-fenil-pirrolidinilmetilpirrolidinamidas substituídas e uso terapêutico das mesmas |
-
2008
- 2008-10-14 WO PCT/US2008/079763 patent/WO2009052068A1/fr active Application Filing
- 2008-10-14 RU RU2010119554/04A patent/RU2478094C2/ru not_active IP Right Cessation
- 2008-10-14 AU AU2008312641A patent/AU2008312641A1/en not_active Abandoned
- 2008-10-14 KR KR1020107010481A patent/KR20100082349A/ko not_active Application Discontinuation
- 2008-10-14 CA CA2702933A patent/CA2702933C/fr not_active Expired - Fee Related
- 2008-10-14 EP EP08838702A patent/EP2215058B1/fr active Active
- 2008-10-14 PT PT08838702T patent/PT2215058E/pt unknown
- 2008-10-14 CN CN2008801212096A patent/CN101903341B/zh not_active Expired - Fee Related
- 2008-10-14 DK DK08838702.2T patent/DK2215058T3/da active
- 2008-10-14 ES ES08838702T patent/ES2378011T3/es active Active
- 2008-10-14 MX MX2010003948A patent/MX2010003948A/es active IP Right Grant
- 2008-10-14 MY MYPI2010001300A patent/MY148807A/en unknown
- 2008-10-14 AT AT08838702T patent/ATE534625T1/de active
- 2008-10-14 PL PL08838702T patent/PL2215058T3/pl unknown
- 2008-10-14 NZ NZ584692A patent/NZ584692A/en not_active IP Right Cessation
- 2008-10-14 RS RS20120067A patent/RS52221B/en unknown
- 2008-10-14 SI SI200830552T patent/SI2215058T1/sl unknown
- 2008-10-14 JP JP2010530054A patent/JP5380455B2/ja not_active Expired - Fee Related
-
2010
- 2010-03-15 US US12/724,045 patent/US8222290B2/en active Active
- 2010-03-25 ZA ZA2010/02114A patent/ZA201002114B/en unknown
- 2010-04-11 IL IL205002A patent/IL205002A0/en unknown
- 2010-05-17 MA MA32842A patent/MA31889B1/fr unknown
-
2011
- 2011-01-12 HK HK11100257.5A patent/HK1146056A1/xx not_active IP Right Cessation
-
2012
- 2012-02-20 HR HR20120166T patent/HRP20120166T1/hr unknown
- 2012-02-23 CY CY20121100185T patent/CY1112391T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
HRP20120166T1 (hr) | 2012-03-31 |
CA2702933A1 (fr) | 2009-04-23 |
MX2010003948A (es) | 2010-04-30 |
RU2010119554A (ru) | 2011-11-27 |
CY1112391T1 (el) | 2015-12-09 |
MY148807A (en) | 2013-05-31 |
JP2011500697A (ja) | 2011-01-06 |
EP2215058A1 (fr) | 2010-08-11 |
ES2378011T3 (es) | 2012-04-04 |
CN101903341A (zh) | 2010-12-01 |
RU2478094C2 (ru) | 2013-03-27 |
PL2215058T3 (pl) | 2012-04-30 |
PT2215058E (pt) | 2012-03-06 |
AU2008312641A1 (en) | 2009-04-23 |
CN101903341B (zh) | 2012-10-03 |
ATE534625T1 (de) | 2011-12-15 |
DK2215058T3 (da) | 2012-03-12 |
ZA201002114B (en) | 2010-12-29 |
NZ584692A (en) | 2011-12-22 |
JP5380455B2 (ja) | 2014-01-08 |
MA31889B1 (fr) | 2010-12-01 |
KR20100082349A (ko) | 2010-07-16 |
US20100173908A1 (en) | 2010-07-08 |
RS52221B (en) | 2012-10-31 |
WO2009052068A1 (fr) | 2009-04-23 |
IL205002A0 (en) | 2010-11-30 |
CA2702933C (fr) | 2012-12-18 |
US8222290B2 (en) | 2012-07-17 |
SI2215058T1 (sl) | 2012-03-30 |
EP2215058B1 (fr) | 2011-11-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20161014 |