HK1140420A1 - Reconstituted surfactants having improved properties - Google Patents
Reconstituted surfactants having improved propertiesInfo
- Publication number
- HK1140420A1 HK1140420A1 HK10106769.4A HK10106769A HK1140420A1 HK 1140420 A1 HK1140420 A1 HK 1140420A1 HK 10106769 A HK10106769 A HK 10106769A HK 1140420 A1 HK1140420 A1 HK 1140420A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- improved properties
- directed
- amino acid
- reconstituted surfactants
- polypeptide
- Prior art date
Links
- 239000004094 surface-active agent Substances 0.000 title abstract 3
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000007620 Pulmonary Surfactant-Associated Protein C Human genes 0.000 abstract 1
- 108010007125 Pulmonary Surfactant-Associated Protein C Proteins 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Fire-Extinguishing Compositions (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07010857A EP1997502A1 (en) | 2007-06-01 | 2007-06-01 | Reconstituted surfactants having improved properties |
| PCT/EP2008/004097 WO2008145298A1 (en) | 2007-06-01 | 2008-05-22 | Reconstituted surfactants having improved properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1140420A1 true HK1140420A1 (en) | 2010-10-15 |
Family
ID=38421186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK10106769.4A HK1140420A1 (en) | 2007-06-01 | 2010-07-13 | Reconstituted surfactants having improved properties |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7897577B2 (ko) |
| EP (2) | EP1997502A1 (ko) |
| JP (1) | JP5575639B2 (ko) |
| KR (1) | KR101516443B1 (ko) |
| CN (1) | CN101687006B (ko) |
| AT (1) | ATE544461T1 (ko) |
| AU (1) | AU2008256449B2 (ko) |
| BR (1) | BRPI0811320A2 (ko) |
| CA (1) | CA2689066C (ko) |
| EA (1) | EA017697B1 (ko) |
| HK (1) | HK1140420A1 (ko) |
| MX (1) | MX2009012675A (ko) |
| WO (1) | WO2008145298A1 (ko) |
| ZA (1) | ZA200908445B (ko) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20021058A1 (it) | 2002-05-17 | 2003-11-17 | Chiesi Farma Spa | Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito |
| SI2078038T1 (sl) | 2006-10-13 | 2014-02-28 | Chiesi Farmaceutici S.P.A. | Rekonstituirani surfaktanti z izboljšanimi lastnostmi |
| EP2022798A1 (en) | 2007-08-09 | 2009-02-11 | CHIESI FARMACEUTICI S.p.A. | Synthetic pulmonary surfactant peptides |
| US8551534B2 (en) * | 2007-10-10 | 2013-10-08 | Parion Sciences, Inc. | Inhaled hypertonic saline delivered by a heated nasal cannula |
| US8399406B2 (en) * | 2009-06-05 | 2013-03-19 | Chiesi Farmaceutici S.P.A. | Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C) |
| CA2838529C (en) | 2011-06-07 | 2020-03-24 | Parion Sciences, Inc. | Methods of treatment |
| US8945605B2 (en) | 2011-06-07 | 2015-02-03 | Parion Sciences, Inc. | Aerosol delivery systems, compositions and methods |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| MY164868A (en) | 2012-03-28 | 2018-01-30 | Discovery Lab Inc | Lyophilization of synthetic liposomal pulmonary surfactant |
| EA032734B1 (ru) | 2012-05-29 | 2019-07-31 | Парион Сайэнс, Инк. | Дендримероподобные аминоамиды, обладающие активностью блокаторов натриевых каналов, для лечения сухости глаз и других заболеваний слизистых оболочек |
| ES2674665T3 (es) | 2012-12-17 | 2018-07-03 | Parion Sciences, Inc. | Compuestos de 3,5-diamino-6-cloro-N-(N-(4-fenilbutilo)carbamimidoilo)-pirazina-2-carboxamida |
| BR112015014178A2 (pt) | 2012-12-17 | 2017-07-11 | Parion Sciences Inc | compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida |
| RS55618B1 (sr) | 2012-12-17 | 2017-06-30 | Parion Sciences Inc | Derivati hloropirazin karboksamida korisni za lečenje bolesti kojima pogoduje nedovoljna hidracija sluznica |
| BR112017006575B1 (pt) | 2014-10-01 | 2023-11-21 | Plant Health Care, Inc | Peptídeo isolado, polipeptídeo de fusão, composição e métodos de conferir resistência à doença às plantas, de potencializar o crescimento da planta, de aumentar a tolerância da planta ao estresse biótico ou ao estresse abiótico e de modular a sinalização bioquímica da planta |
| EP3201223A4 (en) | 2014-10-01 | 2018-06-27 | Plant Health Care, Inc. | Elicitor peptides having disrupted hypersensitive response box and use thereof |
| WO2017176588A1 (en) | 2016-04-06 | 2017-10-12 | Plant Health Care, Inc. | Beneficial microbes for delivery of effector peptides or proteins and use thereof |
| BR112018070141A2 (pt) | 2016-04-06 | 2019-02-12 | Plant Health Care, Inc. | resposta hipersensitiva de peptídeos derivados de eliciador e uso dos mesmos |
| AU2017384467B2 (en) | 2016-12-22 | 2023-10-19 | Chiesi Farmaceutici S.P.A. | A therapeutic combination comprising a pulmonary surfactant and a steroid for the treatment of evolving BPD |
| MX2020011127A (es) | 2018-04-23 | 2021-01-15 | Chiesi Farm Spa | Combinacion terapeutica que comprende agente tensioactivo pulmonar y esteroide para la profilaxis de displasia broncopulmonar (bpd). |
| US20230097886A1 (en) * | 2021-07-30 | 2023-03-30 | Ayuvis Research, Inc. | Compositions and methods for the treatment of bronchopulmonary dysplasia (bpd) and bpd-associated pulmonary hypertension |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260273A (en) | 1988-01-06 | 1993-11-09 | The Scripps Research Institute | Pulmonary surfactant protein and related polypeptide |
| IT1308180B1 (it) | 1999-02-12 | 2001-12-07 | Chiesi Farma Spa | Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante |
| EP1189625A1 (en) * | 1999-06-11 | 2002-03-27 | Byk Gulden Lomberg Chemische Fabrik GmbH | Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c) |
| NZ536796A (en) * | 2002-04-25 | 2007-03-30 | Scripps Research Inst | Treatment and prevention of pulmonary conditions comprising at least one lung surfactant polypeptide and at least one protease inhibitor, lipase inhibitor or an anti-oxidant |
| ITMI20021058A1 (it) * | 2002-05-17 | 2003-11-17 | Chiesi Farma Spa | Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito |
| EP1481665A1 (en) * | 2003-05-30 | 2004-12-01 | CHIESI FARMACEUTICI S.p.A. | Novel lipid mixtures for synthetic surfactants |
| US7582312B2 (en) * | 2004-11-15 | 2009-09-01 | Discovery Laboratories, Inc. | Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof |
| SI2078038T1 (sl) * | 2006-10-13 | 2014-02-28 | Chiesi Farmaceutici S.P.A. | Rekonstituirani surfaktanti z izboljšanimi lastnostmi |
| EP2022798A1 (en) * | 2007-08-09 | 2009-02-11 | CHIESI FARMACEUTICI S.p.A. | Synthetic pulmonary surfactant peptides |
-
2007
- 2007-06-01 EP EP07010857A patent/EP1997502A1/en not_active Withdrawn
-
2008
- 2008-05-22 AT AT08758696T patent/ATE544461T1/de active
- 2008-05-22 EA EA200901459A patent/EA017697B1/ru not_active IP Right Cessation
- 2008-05-22 CN CN2008800171370A patent/CN101687006B/zh not_active Expired - Fee Related
- 2008-05-22 AU AU2008256449A patent/AU2008256449B2/en not_active Ceased
- 2008-05-22 CA CA2689066A patent/CA2689066C/en active Active
- 2008-05-22 JP JP2010509714A patent/JP5575639B2/ja not_active Expired - Fee Related
- 2008-05-22 WO PCT/EP2008/004097 patent/WO2008145298A1/en active Application Filing
- 2008-05-22 MX MX2009012675A patent/MX2009012675A/es active IP Right Grant
- 2008-05-22 EP EP08758696A patent/EP2152288B1/en active Active
- 2008-05-22 BR BRPI0811320-3A2A patent/BRPI0811320A2/pt not_active Application Discontinuation
- 2008-05-22 KR KR1020097022083A patent/KR101516443B1/ko active IP Right Grant
- 2008-06-02 US US12/131,373 patent/US7897577B2/en active Active
-
2009
- 2009-11-30 ZA ZA2009/08445A patent/ZA200908445B/en unknown
-
2010
- 2010-07-13 HK HK10106769.4A patent/HK1140420A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2689066A1 (en) | 2008-12-04 |
| KR101516443B1 (ko) | 2015-05-07 |
| ZA200908445B (en) | 2011-02-23 |
| CN101687006A (zh) | 2010-03-31 |
| EA200901459A1 (ru) | 2010-06-30 |
| EP1997502A1 (en) | 2008-12-03 |
| US7897577B2 (en) | 2011-03-01 |
| WO2008145298A1 (en) | 2008-12-04 |
| US20090088379A1 (en) | 2009-04-02 |
| EA017697B1 (ru) | 2013-02-28 |
| JP2010528997A (ja) | 2010-08-26 |
| CA2689066C (en) | 2016-03-29 |
| EP2152288A1 (en) | 2010-02-17 |
| EP2152288B1 (en) | 2012-02-08 |
| AU2008256449A1 (en) | 2008-12-04 |
| CN101687006B (zh) | 2013-10-16 |
| JP5575639B2 (ja) | 2014-08-20 |
| AU2008256449B2 (en) | 2012-09-13 |
| MX2009012675A (es) | 2009-12-14 |
| ATE544461T1 (de) | 2012-02-15 |
| KR20100015802A (ko) | 2010-02-12 |
| BRPI0811320A2 (pt) | 2014-10-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1140420A1 (en) | Reconstituted surfactants having improved properties | |
| TN2009000099A1 (en) | Reconstituted surfactants having improved properties | |
| TN2011000558A1 (en) | Improved reconstituted surfactant composition containing analogs of surfactant protein b (sp-b) and surfactant protein c (sp-c) | |
| IL210668A (en) | Glucagon-like peptide-2 (2-glp) analogues and their pharmaceutical preparations | |
| HK1205193A1 (en) | Recombinant n-glycosylated proteins from procaryotic cells n- | |
| ATE503768T1 (de) | Synthetische lungensurfactant peptide | |
| MY147920A (en) | Antibacterial and antiviral peptides from actinomadura namibiensis | |
| RS20170169A1 (sr) | Poboljšana rekonstituisana kompozicija sufraktanta koja sadrži analoge sufraktanta proteina b (sp-b) i surfaktanta proteina c (sp-c) | |
| TH127104B (th) | สารลดความตึงผิวที่ถูกประกอบขึ้นใหม่โดยมีคุณสมบัติที่ได้รับการปรับปรุงให้ดีขึ้น |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20230522 |