HK1139861A1 - 磷酸二酯酶 抑制劑用在治療肢體活動障礙 - Google Patents

磷酸二酯酶 抑制劑用在治療肢體活動障礙

Info

Publication number
HK1139861A1
HK1139861A1 HK10106488.4A HK10106488A HK1139861A1 HK 1139861 A1 HK1139861 A1 HK 1139861A1 HK 10106488 A HK10106488 A HK 10106488A HK 1139861 A1 HK1139861 A1 HK 1139861A1
Authority
HK
Hong Kong
Prior art keywords
pde7
treatment
movement disorders
inhibitors
pde7 inhibitors
Prior art date
Application number
HK10106488.4A
Other languages
English (en)
Inventor
John E Bergmann
Neil S Cutshall
Gregory A Demopulos
Vincent A Florio
George Gaitanaris
Patrick Gray
John Hohmann
Rene Onrust
Hongkui Zeng
Original Assignee
Omeros Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omeros Corp filed Critical Omeros Corp
Publication of HK1139861A1 publication Critical patent/HK1139861A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/527—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK10106488.4A 2007-03-27 2010-07-05 磷酸二酯酶 抑制劑用在治療肢體活動障礙 HK1139861A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92049607P 2007-03-27 2007-03-27
PCT/US2008/058530 WO2008119057A2 (en) 2007-03-27 2008-03-27 The use of pde7 inhibitors for the treatment of movement disorders

Publications (1)

Publication Number Publication Date
HK1139861A1 true HK1139861A1 (zh) 2010-09-30

Family

ID=39789284

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10106488.4A HK1139861A1 (zh) 2007-03-27 2010-07-05 磷酸二酯酶 抑制劑用在治療肢體活動障礙

Country Status (13)

Country Link
US (3) US20080260643A1 (zh)
EP (1) EP2139475B1 (zh)
JP (2) JP5580192B2 (zh)
CN (2) CN104758291B (zh)
AU (1) AU2008230710B2 (zh)
BR (1) BRPI0809244A2 (zh)
CA (1) CA2681650C (zh)
ES (1) ES2533206T3 (zh)
HK (1) HK1139861A1 (zh)
MX (1) MX2009010450A (zh)
NZ (1) NZ580413A (zh)
RU (1) RU2449790C2 (zh)
WO (1) WO2008119057A2 (zh)

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US8637528B2 (en) 2007-03-27 2014-01-28 Omeros Corporation Use of PDE7 inhibitors for the treatment of movement disorders
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FR2944282B1 (fr) 2009-04-09 2013-05-03 Sanofi Aventis Derives de quinazolinedione, leur preparation et leurs diverses applications therapeutiques
FR2944206B1 (fr) 2009-04-09 2012-12-28 Sanofi Aventis Applications therapeutiques dans le domaine cardiovasculaire de derives de quinazolinedione
AU2013202493B2 (en) * 2009-05-04 2016-03-10 Omeros Corporation Use of PDE7 inhibitors for the treatment of movement disorders
ES2353093B1 (es) * 2009-05-20 2012-01-03 Consejo Superior De Investigaciones Científicas (Csic) Uso de derivados de quinazolinas y sus composiciones farmacéuticas en enfermedades neurodegenerativas.
ES2360783B1 (es) 2009-10-02 2012-07-04 Consejo Superior De Investigaciones Científicas (Csic) 1,2,4-tiadiazoles-5-imino sustituidos utiles en el tratamiento de enfermedades neurodegenerativas
US9220715B2 (en) 2010-11-08 2015-12-29 Omeros Corporation Treatment of addiction and impulse-control disorders using PDE7 inhibitors
KR102385359B1 (ko) 2010-11-08 2022-04-11 오메로스 코포레이션 Pde7 억제제를 사용한 중독 및 충동-조절 장애의 치료
DK2846805T3 (en) * 2012-05-07 2019-03-18 Omeros Corp TREATMENT OF DEPENDENCE AND IMPULSE CONTROL DISORDERS USING PDE7 INHIBITORS
IN2014DN10404A (zh) * 2012-05-07 2015-08-14 Omeros Corp
WO2018038265A1 (ja) * 2016-08-26 2018-03-01 田辺三菱製薬株式会社 二環式含窒素複素環化合物
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Also Published As

Publication number Publication date
RU2009138966A (ru) 2011-05-10
AU2008230710B2 (en) 2014-04-10
CA2681650A1 (en) 2008-10-02
CN101917992A (zh) 2010-12-15
MX2009010450A (es) 2009-11-23
JP2010522768A (ja) 2010-07-08
RU2449790C2 (ru) 2012-05-10
CA2681650C (en) 2016-11-22
JP5943964B2 (ja) 2016-07-05
EP2139475A2 (en) 2010-01-06
BRPI0809244A2 (pt) 2014-09-23
AU2008230710A1 (en) 2008-10-02
EP2139475A4 (en) 2012-03-07
WO2008119057A3 (en) 2008-11-20
WO2008119057A2 (en) 2008-10-02
US20080260643A1 (en) 2008-10-23
EP2139475B1 (en) 2014-12-17
CN104758291A (zh) 2015-07-08
JP5580192B2 (ja) 2014-08-27
US20190183824A1 (en) 2019-06-20
JP2014198718A (ja) 2014-10-23
ES2533206T3 (es) 2015-04-08
NZ580413A (en) 2012-11-30
CN104758291B (zh) 2020-03-03
US20110091388A1 (en) 2011-04-21

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