HK1135692A1 - Camptothecin derivatives with antitumor activity - Google Patents

Camptothecin derivatives with antitumor activity

Info

Publication number
HK1135692A1
HK1135692A1 HK10100447.7A HK10100447A HK1135692A1 HK 1135692 A1 HK1135692 A1 HK 1135692A1 HK 10100447 A HK10100447 A HK 10100447A HK 1135692 A1 HK1135692 A1 HK 1135692A1
Authority
HK
Hong Kong
Prior art keywords
antitumor activity
camptothecin derivatives
camptothecin
derivatives
antitumor
Prior art date
Application number
HK10100447.7A
Other languages
English (en)
Inventor
Gabriele Fontana
Ezio Bombardelli
Carla Manzotti
Arturo Battaglia
Cristian Samori
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of HK1135692A1 publication Critical patent/HK1135692A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
HK10100447.7A 2006-07-26 2010-01-15 Camptothecin derivatives with antitumor activity HK1135692A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001474A ITMI20061474A1 (it) 2006-07-26 2006-07-26 Derivati della camptotecina ad attivita antitumorale
PCT/EP2007/006294 WO2008012003A1 (en) 2006-07-26 2007-07-16 Camptothecin derivatives with antitumor activity

Publications (1)

Publication Number Publication Date
HK1135692A1 true HK1135692A1 (en) 2010-06-11

Family

ID=38668855

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10100447.7A HK1135692A1 (en) 2006-07-26 2010-01-15 Camptothecin derivatives with antitumor activity

Country Status (20)

Country Link
US (1) US8193210B2 (xx)
EP (1) EP2044080B1 (xx)
JP (1) JP5313895B2 (xx)
KR (1) KR101496374B1 (xx)
CN (1) CN101495485B (xx)
AU (1) AU2007278509B2 (xx)
BR (1) BRPI0714672B8 (xx)
CA (1) CA2658902C (xx)
DK (1) DK2044080T3 (xx)
ES (1) ES2628022T3 (xx)
HK (1) HK1135692A1 (xx)
IL (1) IL196652A0 (xx)
IT (1) ITMI20061474A1 (xx)
MX (1) MX2009000828A (xx)
NO (1) NO342506B1 (xx)
PL (1) PL2044080T3 (xx)
PT (1) PT2044080T (xx)
RU (1) RU2450007C2 (xx)
SI (1) SI2044080T1 (xx)
WO (1) WO2008012003A1 (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9379559B2 (en) 2012-02-03 2016-06-28 International Business Machines Corporation System and method of charging a vehicle using a dynamic power grid, and system and method of managing power consumption in the vehicle
PL235836B1 (pl) * 2012-10-25 2020-11-02 Inst Chemii Organicznej Polskiej Akademii Nauk Pochodne kamptotecyny, sposób ich otrzymywania i zastosowanie
CN108690036B (zh) * 2018-05-22 2021-05-25 北京海步医药科技股份有限公司 一种10-二氟甲基喜树碱类化合物及其制备方法和应用
LU102067B1 (en) 2020-09-17 2022-03-18 Narodowy Inst Lekow 7-Ethyl-10-hydroxycamptothecin derivatives for use in the treatment of cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972955A (en) * 1995-06-06 1999-10-26 Dr. Reddy's Research Foundation Water soluble C-ring analogues of 20(S)-camptothecin
IT1282673B1 (it) * 1996-02-23 1998-03-31 Ist Naz Stud Cura Dei Tumori Derivati della camptotecina e loro uso come agenti antitumorali

Also Published As

Publication number Publication date
AU2007278509A1 (en) 2008-01-31
JP2010500971A (ja) 2010-01-14
KR20090032100A (ko) 2009-03-31
CA2658902C (en) 2014-09-23
EP2044080B1 (en) 2017-05-10
RU2009102241A (ru) 2010-07-27
WO2008012003A1 (en) 2008-01-31
CA2658902A1 (en) 2008-01-31
EP2044080A1 (en) 2009-04-08
BRPI0714672B8 (pt) 2021-05-25
AU2007278509B2 (en) 2012-10-04
ES2628022T3 (es) 2017-08-01
CN101495485B (zh) 2012-04-11
DK2044080T3 (en) 2017-07-17
US8193210B2 (en) 2012-06-05
US20100010032A1 (en) 2010-01-14
CN101495485A (zh) 2009-07-29
SI2044080T1 (sl) 2017-07-31
NO342506B1 (no) 2018-06-04
IL196652A0 (en) 2009-11-18
NO20090252L (no) 2009-01-16
RU2450007C2 (ru) 2012-05-10
BRPI0714672A2 (pt) 2013-03-26
MX2009000828A (es) 2009-02-03
PL2044080T3 (pl) 2017-10-31
PT2044080T (pt) 2017-06-15
KR101496374B1 (ko) 2015-03-04
BRPI0714672B1 (pt) 2020-10-20
JP5313895B2 (ja) 2013-10-09
ITMI20061474A1 (it) 2008-01-27

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20210720