HK1134495A1 - Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof - Google Patents

Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof

Info

Publication number
HK1134495A1
HK1134495A1 HK10100169.3A HK10100169A HK1134495A1 HK 1134495 A1 HK1134495 A1 HK 1134495A1 HK 10100169 A HK10100169 A HK 10100169A HK 1134495 A1 HK1134495 A1 HK 1134495A1
Authority
HK
Hong Kong
Prior art keywords
methods
polynucleotides encoding
modifying enzymes
isoprenoid modifying
encoding isoprenoid
Prior art date
Application number
HK10100169.3A
Other languages
English (en)
Inventor
Dae-Kyun Ro
Karyn Newman
Eric M Paradise
Jay D Keasling
Mario Ouellet
Rachel Eachus
Kimberly Ho
Timothy Ham
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of HK1134495A1 publication Critical patent/HK1134495A1/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042NADPH-cytochrome P450 reductase (1.6.2.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y106/00Oxidoreductases acting on NADH or NADPH (1.6)
    • C12Y106/02Oxidoreductases acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12Y106/02004NADPH-hemoprotein reductase (1.6.2.4), i.e. NADP-cytochrome P450-reductase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
HK10100169.3A 2005-07-05 2010-01-08 Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof HK1134495A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69706705P 2005-07-05 2005-07-05
PCT/US2006/025572 WO2007005604A2 (en) 2005-07-05 2006-06-29 Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof

Publications (1)

Publication Number Publication Date
HK1134495A1 true HK1134495A1 (en) 2010-04-30

Family

ID=37605033

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10100169.3A HK1134495A1 (en) 2005-07-05 2010-01-08 Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof

Country Status (19)

Country Link
US (2) US8163980B2 (ko)
EP (2) EP2489672B1 (ko)
JP (1) JP2009504138A (ko)
KR (2) KR101444090B1 (ko)
CN (4) CN106939323B (ko)
AP (1) AP3827A (ko)
BR (1) BRPI0612411B8 (ko)
CA (1) CA2613469C (ko)
DK (1) DK1919514T3 (ko)
ES (2) ES2621657T3 (ko)
HK (1) HK1134495A1 (ko)
IL (1) IL188376A (ko)
MX (1) MX2008000200A (ko)
PL (1) PL1919514T3 (ko)
PT (1) PT1919514E (ko)
SG (1) SG176459A1 (ko)
SI (1) SI1919514T1 (ko)
WO (1) WO2007005604A2 (ko)
ZA (1) ZA200800889B (ko)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1778831B1 (en) 2004-07-27 2012-05-23 The Regents of The University of California Genetically modified host cells and use of same for producing isoprenoid compounds
JP2009504138A (ja) * 2005-07-05 2009-02-05 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア イソプレノイド修飾酵素をコードするポリヌクレオチド、およびその使用方法
SG172646A1 (en) 2006-05-26 2011-07-28 Amyris Biotechnologies Inc Production of isoprenoids
EP2066778B1 (en) * 2006-09-26 2016-01-27 The Regents of The University of California Production of isoprenoids and isoprenoid precursors
EP2171085A4 (en) 2007-06-01 2010-07-14 Sapphire Energy SCREENING OF GENETICALLY MODIFIED PHOTOSYNTHETIC ORGANISMS WITH HIGH THROUGHPUT
GB2463337B (en) 2007-09-11 2012-11-21 Sapphire Energy Inc Methods of producing organic products with photosynthetic organisms
EP2444415A1 (en) * 2010-10-20 2012-04-25 Genoplante-Valor 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
HUE034344T2 (en) * 2011-11-01 2018-02-28 Firmenich & Cie Cytochrome P450 and its use for enzymatic oxidation of terpenes
JP5827601B2 (ja) * 2012-07-04 2015-12-02 住友ゴム工業株式会社 特定の蛋白質の発現を光応答転写因子により調整する方法、光応答転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法
SG11201500682WA (en) * 2012-09-07 2015-02-27 Sanofi Sa Fusion proteins for treating a metabolic syndrome
PL224377B1 (pl) * 2012-11-02 2016-12-30 Inst Biochemii I Biofizyki Polskiej Akademii Nauk Szczep Trichoderma atroviride, sposób otrzymywania i zastosowanie szczepu Trichoderma atroviride jako środka biobójczego
JP6410802B2 (ja) * 2013-09-19 2018-10-24 フイルメニツヒ ソシエテ アノニムFirmenich Sa 芳香性アルコールの製造方法
JP6475336B2 (ja) * 2014-08-21 2019-02-27 チュン−アン ユニヴァーシティ インダストリー−アカデミー コーポレーション ファウンデーションChung−Ang University Industry−Academy Cooperation Foundation rDNA NTS基盤の遺伝子多重挿入カセットセット、及びそれを用いたGRAS等級の組換え酵母菌株
WO2016168681A1 (en) * 2015-04-15 2016-10-20 William Marsh Rice University Iterative platform for the synthesis of alpha functionalized products
US11697830B2 (en) * 2015-04-15 2023-07-11 Ramon Gonzalez Iterative platform for the synthesis of alpha functionalized products
CN105177007B (zh) * 2015-10-30 2017-11-10 上海交通大学 一种调控基因在非分泌型腺毛中表达的启动子及其应用
CN105274109B (zh) * 2015-10-30 2017-12-29 上海交通大学 一种调控基因在非分泌型腺毛中表达的启动子及其应用
CN105483236A (zh) * 2015-12-26 2016-04-13 吉林省农业科学院 转基因植物中cry1C基因的LAMP检测引物组、试剂盒及检测方法
CN105567685B (zh) * 2016-01-18 2018-07-13 上海交通大学 AaPDR3基因启动子及其应用
MX2019003063A (es) 2016-09-20 2019-10-14 22Nd Century Ltd Llc Promotores específicos de tricoma para la manipulación de cannabinoides y otros compuestos en tricomas glandulares.
WO2018111194A1 (en) * 2016-12-16 2018-06-21 Temasek Life Sciences Laboratory Limited Targets for improving terpene production in rhodosporidium toruloides
CA3056929A1 (en) 2017-03-24 2018-09-27 Trait Biosciences, Inc. High level in vivo biosynthesis and isolation of water-soluble cannabinoids in plant systems
US11946059B2 (en) 2017-07-11 2024-04-02 Trait Biosciences, Inc. In vivo generation of water-soluble cannabinoids in plant cell suspension cultures
CN111465700A (zh) 2017-07-11 2020-07-28 特征生物科学公司 在酵母和植物细胞悬浮培养物中产生水溶性大麻素化合物和材料组合物
US11905543B2 (en) 2017-07-11 2024-02-20 Trait Biosceinces, Inc. In vivo generation of water-soluble acetylated cannabinoid glycoside compounds in plant cell suspension cultures
WO2021150960A1 (en) * 2020-01-23 2021-07-29 Amyris, Inc. Amorpha-4,11-diene 12-monooxygenase variants and uses thereof
CN111621508B (zh) * 2020-06-11 2022-07-01 云南中烟工业有限责任公司 烟草萜类合成酶NtTPS7基因及其载体与应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
ES2196005T3 (es) * 1992-03-27 2003-12-16 Int Flower Dev Pty Ltd Secuencias geneticas que codifican enzimas de la ruta flavonoide con actividad flavonoide -3`-hidroxilasa y sus usos.
FR2689905B1 (fr) * 1992-04-13 1995-07-13 Orsan Procede de clonage d'une sequence d'adn codant pour une nadph cytochrome p450 reductase et sequences d'adn codant pour une nadph-cytochrome p450 reductase, notamment de plantes.
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
US5545817A (en) 1994-03-11 1996-08-13 Calgene, Inc. Enhanced expression in a plant plastid
CZ296981B6 (cs) 1994-12-09 2006-08-16 Imperial College Innovations Limited Zpusob pro identifikaci mikroorganizmu, zpusob identifikování genu, mikroorganizmus, vakcína a zpusob její prípravy, zpusob získání mutantního mikroorganizmu, zpusob prípravy farmaceutického prostredku, zpusob identifikace slouceniny a zpusob príprav
HUP0002926A3 (en) * 1997-03-07 2005-11-28 Syngenta Participations Ag Cytochrome p450 monooxygenases
US6900012B1 (en) 1997-06-03 2005-05-31 The University Of Chicago Plant artificial chromosome compositions and methods
US6083731A (en) 1997-06-24 2000-07-04 Washington State University Research Foundation Recombinant materials and methods for the production of limonene hydroxylases
US6080849A (en) 1997-09-10 2000-06-27 Vion Pharmaceuticals, Inc. Genetically modified tumor-targeted bacteria with reduced virulence
EP0982404A1 (en) * 1998-08-27 2000-03-01 Wallaart, Thorvald Eelco DNA encoding amorpha-4,11-diene synthase
US6645747B1 (en) 1999-09-21 2003-11-11 E. I. Du Pont De Nemours And Company Cis-prenyltransferases from plants
US6369212B1 (en) 2000-02-07 2002-04-09 Korea Kumbo Petrochemical Co., Ltd. Cytochrome P450 gene highly expressed in the incompatible interaction
EP1354955A4 (en) * 2000-12-28 2005-01-05 Toyota Motor Co Ltd PROCESS FOR PREPARING PRENYL ALCOHOL
GB0105924D0 (en) 2001-03-09 2001-04-25 Microscience Ltd Promoter
ATE513046T1 (de) * 2001-03-09 2011-07-15 Univ Kentucky Res Found Cytochrom p450s und verwendungen davon
AUPR446701A0 (en) * 2001-04-18 2001-05-17 Gene Stream Pty Ltd Transgenic mammals for pharmacological and toxicological studies
JP2005503163A (ja) 2001-09-17 2005-02-03 プラント リサーチ インターナショナル ビー. ブイ. 生物的転化のための植物酵素
US20040162420A1 (en) * 2002-10-16 2004-08-19 U.S. Smokeless Tobacco Company Cloning of cytochrome p450 genes from nicotiana
US7192751B2 (en) 2001-12-06 2007-03-20 The Regents Of The University Of California Biosynthesis of amorpha-4,11-diene
US7172886B2 (en) 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
US6733996B2 (en) 2002-08-26 2004-05-11 Trustees Of Dartmouth College Methods for regulating gene expression using light
JP2009504138A (ja) * 2005-07-05 2009-02-05 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア イソプレノイド修飾酵素をコードするポリヌクレオチド、およびその使用方法
CA2630305A1 (en) * 2005-10-24 2007-05-03 National Research Council Of Canada A novel gene encoding amorphadiene hydroxylase and a process to produce artemisinic alcohol therewith

Also Published As

Publication number Publication date
WO2007005604A3 (en) 2008-12-31
BRPI0612411B1 (pt) 2020-05-05
DK1919514T3 (da) 2012-08-20
KR20130054468A (ko) 2013-05-24
KR101444090B1 (ko) 2014-09-26
CA2613469C (en) 2014-08-12
CN106939323A (zh) 2017-07-11
WO2007005604A2 (en) 2007-01-11
PT1919514E (pt) 2012-08-16
CA2613469A1 (en) 2007-01-11
US8163980B2 (en) 2012-04-24
KR20080031054A (ko) 2008-04-07
SI1919514T1 (sl) 2012-08-31
BRPI0612411A8 (pt) 2017-12-26
BRPI0612411A2 (pt) 2010-11-09
CN103667370A (zh) 2014-03-26
IL188376A0 (en) 2008-04-13
ES2386554T3 (es) 2012-08-22
JP2009504138A (ja) 2009-02-05
CN103667370B (zh) 2016-08-10
AP2013006962A0 (en) 2013-07-31
CN106939323B (zh) 2021-07-13
MX2008000200A (es) 2008-04-07
SG176459A1 (en) 2011-12-29
PL1919514T3 (pl) 2012-10-31
ZA200800889B (en) 2009-09-30
BRPI0612411B8 (pt) 2021-05-25
CN101495499A (zh) 2009-07-29
US20100218283A1 (en) 2010-08-26
EP1919514A4 (en) 2009-12-02
EP2489672A2 (en) 2012-08-22
AP3827A (en) 2016-09-30
CN101495499B (zh) 2013-09-04
KR101487304B1 (ko) 2015-01-28
EP1919514B1 (en) 2012-05-16
EP2489672B1 (en) 2017-01-18
IL188376A (en) 2012-12-31
US20120288905A1 (en) 2012-11-15
EP2489672A3 (en) 2013-01-09
ES2621657T3 (es) 2017-07-04
CN105950667A (zh) 2016-09-21
US8759632B2 (en) 2014-06-24
EP1919514A2 (en) 2008-05-14

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Effective date: 20170629