HK1134042A1 - Identification of a micro-rna that activates expression of - Google Patents
Identification of a micro-rna that activates expression ofInfo
- Publication number
- HK1134042A1 HK1134042A1 HK10102134.1A HK10102134A HK1134042A1 HK 1134042 A1 HK1134042 A1 HK 1134042A1 HK 10102134 A HK10102134 A HK 10102134A HK 1134042 A1 HK1134042 A1 HK 1134042A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- identification
- rna
- micro
- treatment
- function
- Prior art date
Links
- 108091070501 miRNA Proteins 0.000 title 1
- 239000000835 fiber Substances 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 108010068426 Contractile Proteins Proteins 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 206010020880 Hypertrophy Diseases 0.000 abstract 1
- 108091092539 MiR-208 Proteins 0.000 abstract 1
- 108700011259 MicroRNAs Proteins 0.000 abstract 1
- 208000023178 Musculoskeletal disease Diseases 0.000 abstract 1
- 230000003416 augmentation Effects 0.000 abstract 1
- 230000009787 cardiac fibrosis Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000002679 microRNA Substances 0.000 abstract 1
- 210000002027 skeletal muscle Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0375—Animal model for cardiovascular diseases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
- C12N2310/141—MicroRNAs, miRNAs
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/10—Production naturally occurring
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Environmental Sciences (AREA)
- Analytical Chemistry (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83466706P | 2006-08-01 | 2006-08-01 | |
US95291107P | 2007-07-31 | 2007-07-31 | |
US95291707P | 2007-07-31 | 2007-07-31 | |
PCT/US2007/074866 WO2008016924A2 (en) | 2006-08-01 | 2007-07-31 | Identification of a micro-rna that activates expression of beta-myosin heavy chain |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1134042A1 true HK1134042A1 (en) | 2010-04-16 |
Family
ID=38896739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10102134.1A HK1134042A1 (en) | 2006-08-01 | 2010-03-01 | Identification of a micro-rna that activates expression of |
Country Status (17)
Country | Link |
---|---|
US (1) | US8304397B2 (xx) |
EP (2) | EP2434017A3 (xx) |
JP (2) | JP5718570B2 (xx) |
KR (1) | KR101485495B1 (xx) |
CN (1) | CN101522222B (xx) |
AU (1) | AU2007281261B2 (xx) |
BR (1) | BRPI0714794A2 (xx) |
CA (1) | CA2659364C (xx) |
CY (1) | CY1113539T1 (xx) |
DK (1) | DK2056882T3 (xx) |
ES (1) | ES2397439T3 (xx) |
HK (1) | HK1134042A1 (xx) |
MX (1) | MX2009001281A (xx) |
NZ (1) | NZ574563A (xx) |
PL (1) | PL2056882T3 (xx) |
PT (1) | PT2056882E (xx) |
WO (1) | WO2008016924A2 (xx) |
Families Citing this family (25)
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PL2056882T3 (pl) | 2006-08-01 | 2013-03-29 | Univ Texas | Identyfikacja mikro-RNA, który aktywuje ekspresję łańcucha ciężkiego beta-miozyny |
US20090306181A1 (en) * | 2006-09-29 | 2009-12-10 | Children's Medical Center Corporation | Compositions and methods for evaluating and treating heart failure |
US20100305195A1 (en) * | 2006-11-10 | 2010-12-02 | The Uab Research Foundation | microrna mediator of cardiomyopathy and heart failure |
WO2008076324A2 (en) * | 2006-12-14 | 2008-06-26 | Novartis Ag | Compositions and methods to treat muscular & cardiovascular disorders |
US8440636B2 (en) * | 2007-07-31 | 2013-05-14 | The Board Of Regents, The University Of Texas System | Micro-RNA family that modulates fibrosis and uses thereof |
CN105030808B (zh) * | 2007-07-31 | 2018-12-14 | 得克萨斯系统大学董事会 | 调控纤维化的微小rna家族及其用途 |
AU2008283794B2 (en) | 2007-07-31 | 2014-03-20 | Board Of Regents, The University Of Texas System | Micro-RNAs that control myosin expression and myofiber identity |
EP2331143B1 (en) * | 2008-09-04 | 2016-08-17 | Universität Zürich Prorektorat Mnw | Treatment of scleroderma |
AU2010210605B2 (en) | 2009-02-04 | 2015-08-13 | Board Of Regents, The University Of Texas System | Dual targeting of miR-208 and miR-499 in the treatment of cardiac disorders |
EP2427472B1 (en) | 2009-05-05 | 2016-06-22 | Miragen Therapeutics | Lipophilic polynucleotide conjugates |
WO2011154553A2 (en) * | 2010-06-11 | 2011-12-15 | Cellartis Ab | Novel micrornas for the detection and isolaton of human embryonic stem cell-derived cardiac cell types |
CN103492569B (zh) | 2010-11-05 | 2020-04-07 | 米拉根医疗公司 | 碱基经修饰的寡核苷酸 |
EP2652151A2 (en) | 2010-12-15 | 2013-10-23 | Miragen Therapeutics | Microrna inhibitors comprising locked nucleotides |
CN104011208B (zh) * | 2011-09-06 | 2020-04-10 | 马普科技促进协会 | 作为治疗靶的miRNA-212/132家族 |
AU2013201303C1 (en) * | 2011-10-06 | 2016-06-23 | MiRagen Therapeutics, Inc. | Control of whole body energy homeostasis by microRNA regulation |
US9388408B2 (en) | 2012-06-21 | 2016-07-12 | MiRagen Therapeutics, Inc. | Oligonucleotide-based inhibitors comprising locked nucleic acid motif |
CN102719436A (zh) * | 2012-06-27 | 2012-10-10 | 南开大学 | 一种寡核苷酸及其制备在防治心肌肥大与心力衰竭药物中的用途 |
US10076384B2 (en) | 2013-03-08 | 2018-09-18 | Symple Surgical, Inc. | Balloon catheter apparatus with microwave emitter |
EP2968396B1 (en) | 2013-03-15 | 2018-12-19 | Miragen Therapeutics, Inc. | Locked nucleic acid inhibitor of mir-145 and uses thereof |
GB201400598D0 (en) | 2014-01-14 | 2014-03-05 | Univ Glasgow | Materials and methods for modulation of tendon healing |
JP2018503646A (ja) | 2015-01-20 | 2018-02-08 | ミラゲン セラピューティクス, インコーポレイテッド | miR−92阻害剤およびその使用 |
CN105695606B (zh) * | 2016-04-07 | 2020-08-28 | 昆明理工大学 | 用于非治疗目的的肥厚型心肌病相关致病基因突变的筛查方法 |
US10150115B2 (en) * | 2016-07-21 | 2018-12-11 | Spacepharma SA | System and method for rehydrating powder and delivering the rehydrated powder to a reactor |
WO2018047148A1 (en) | 2016-09-12 | 2018-03-15 | Novartis Ag | Compounds for the inhibition of mirna |
CN109097461B (zh) * | 2018-09-06 | 2021-07-30 | 北京中关村生命科学园生物医药科技孵化有限公司 | 一种心肌病相关基因检测试剂及其应用 |
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EP2476762B1 (de) | 2006-10-09 | 2014-01-08 | Julius-Maximilians-Universität Würzburg | MicroRNA (miRNA) zur Diagnose und Therapie von Herzerkrankungen |
JP2010509923A (ja) | 2006-11-23 | 2010-04-02 | ミルクス セラピューティクス アンパーツゼルスカブ | 標的rnaの活性を変化させるためのオリゴヌクレオチド |
WO2008076324A2 (en) | 2006-12-14 | 2008-06-26 | Novartis Ag | Compositions and methods to treat muscular & cardiovascular disorders |
US20090137504A1 (en) | 2006-12-21 | 2009-05-28 | Soren Morgenthaler Echwald | Microrna target site blocking oligos and uses thereof |
CA2687336C (en) | 2007-05-23 | 2014-12-23 | Dharmacon, Inc. | Micro-rna scaffolds and non-naturally occurring micro-rnas |
EP2192925A4 (en) | 2007-08-23 | 2013-04-03 | Keren Pharmaceuticals | TARGETING RNA WITH EXTERNAL GUIDE SEQUENCES |
-
2007
- 2007-07-31 PL PL07813595T patent/PL2056882T3/pl unknown
- 2007-07-31 CN CN2007800367837A patent/CN101522222B/zh not_active Expired - Fee Related
- 2007-07-31 NZ NZ574563A patent/NZ574563A/en not_active IP Right Cessation
- 2007-07-31 MX MX2009001281A patent/MX2009001281A/es active IP Right Grant
- 2007-07-31 EP EP11190352A patent/EP2434017A3/en not_active Withdrawn
- 2007-07-31 CA CA2659364A patent/CA2659364C/en not_active Expired - Fee Related
- 2007-07-31 PT PT07813595T patent/PT2056882E/pt unknown
- 2007-07-31 JP JP2009523016A patent/JP5718570B2/ja not_active Expired - Fee Related
- 2007-07-31 BR BRPI0714794-5A patent/BRPI0714794A2/pt not_active Application Discontinuation
- 2007-07-31 WO PCT/US2007/074866 patent/WO2008016924A2/en active Application Filing
- 2007-07-31 KR KR1020097004411A patent/KR101485495B1/ko not_active IP Right Cessation
- 2007-07-31 ES ES07813595T patent/ES2397439T3/es active Active
- 2007-07-31 US US11/831,427 patent/US8304397B2/en not_active Expired - Fee Related
- 2007-07-31 DK DK07813595.1T patent/DK2056882T3/da active
- 2007-07-31 AU AU2007281261A patent/AU2007281261B2/en not_active Ceased
- 2007-07-31 EP EP07813595A patent/EP2056882B1/en not_active Not-in-force
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2010
- 2010-03-01 HK HK10102134.1A patent/HK1134042A1/xx not_active IP Right Cessation
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2013
- 2013-01-11 CY CY20131100028T patent/CY1113539T1/el unknown
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Also Published As
Publication number | Publication date |
---|---|
US20090180957A1 (en) | 2009-07-16 |
EP2434017A2 (en) | 2012-03-28 |
EP2434017A3 (en) | 2012-09-05 |
JP5798165B2 (ja) | 2015-10-21 |
CN101522222A (zh) | 2009-09-02 |
NZ574563A (en) | 2012-02-24 |
MX2009001281A (es) | 2009-04-16 |
KR101485495B1 (ko) | 2015-01-22 |
KR20090037968A (ko) | 2009-04-16 |
BRPI0714794A2 (pt) | 2013-05-21 |
EP2056882A2 (en) | 2009-05-13 |
CA2659364A1 (en) | 2008-02-07 |
CA2659364C (en) | 2017-08-22 |
ES2397439T3 (es) | 2013-03-07 |
WO2008016924A2 (en) | 2008-02-07 |
EP2056882B1 (en) | 2012-10-24 |
PL2056882T3 (pl) | 2013-03-29 |
WO2008016924A3 (en) | 2008-08-07 |
AU2007281261B2 (en) | 2013-03-21 |
PT2056882E (pt) | 2012-11-19 |
CN101522222B (zh) | 2012-04-18 |
JP5718570B2 (ja) | 2015-05-13 |
US8304397B2 (en) | 2012-11-06 |
JP2014001243A (ja) | 2014-01-09 |
AU2007281261A1 (en) | 2008-02-07 |
CY1113539T1 (el) | 2016-06-22 |
JP2009545615A (ja) | 2009-12-24 |
DK2056882T3 (da) | 2012-11-19 |
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