HK1131169A1 - Peptide vaccines for cancers expressing mphosph1 or depdc1 polypeptides - Google Patents

Peptide vaccines for cancers expressing mphosph1 or depdc1 polypeptides

Info

Publication number
HK1131169A1
HK1131169A1 HK09110942.9A HK09110942A HK1131169A1 HK 1131169 A1 HK1131169 A1 HK 1131169A1 HK 09110942 A HK09110942 A HK 09110942A HK 1131169 A1 HK1131169 A1 HK 1131169A1
Authority
HK
Hong Kong
Prior art keywords
peptide vaccines
cancers expressing
expressing mphosph1
depdc1
polypeptides
Prior art date
Application number
HK09110942.9A
Other languages
English (en)
Inventor
Tomoaki Fujioka
Yusuke Nakamura
Takuya Tsunoda
Ryuji Osawa
Midori Shida
Original Assignee
Oncotherapy Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncotherapy Science Inc filed Critical Oncotherapy Science Inc
Publication of HK1131169A1 publication Critical patent/HK1131169A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
HK09110942.9A 2006-10-17 2009-11-23 Peptide vaccines for cancers expressing mphosph1 or depdc1 polypeptides HK1131169A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85257506P 2006-10-17 2006-10-17
PCT/JP2007/001122 WO2008047473A1 (fr) 2006-10-17 2007-10-16 Vaccins peptidiques pour des cancers exprimant les polypeptides mphosph1 ou depdc1

Publications (1)

Publication Number Publication Date
HK1131169A1 true HK1131169A1 (en) 2010-01-15

Family

ID=39313729

Family Applications (4)

Application Number Title Priority Date Filing Date
HK09110942.9A HK1131169A1 (en) 2006-10-17 2009-11-23 Peptide vaccines for cancers expressing mphosph1 or depdc1 polypeptides
HK12111316.0A HK1171026A1 (en) 2006-10-17 2009-11-23 Peptide vaccines for cancers expressing depdc1 polypeptides depdc1
HK12111315.1A HK1171025A1 (en) 2006-10-17 2009-11-23 Peptide vaccines for cancers expressing depdc1 polypeptides depdc1
HK12111314.2A HK1171024A1 (en) 2006-10-17 2009-11-23 Peptide vaccines for cancers expressing mphosph1 polypeptides mphosph1

Family Applications After (3)

Application Number Title Priority Date Filing Date
HK12111316.0A HK1171026A1 (en) 2006-10-17 2009-11-23 Peptide vaccines for cancers expressing depdc1 polypeptides depdc1
HK12111315.1A HK1171025A1 (en) 2006-10-17 2009-11-23 Peptide vaccines for cancers expressing depdc1 polypeptides depdc1
HK12111314.2A HK1171024A1 (en) 2006-10-17 2009-11-23 Peptide vaccines for cancers expressing mphosph1 polypeptides mphosph1

Country Status (18)

Country Link
US (5) US8557955B2 (fr)
EP (7) EP2687541A1 (fr)
JP (2) JP5339292B2 (fr)
KR (4) KR101543622B1 (fr)
CN (5) CN102850435B (fr)
AU (1) AU2007311395B2 (fr)
BR (1) BRPI0717651A2 (fr)
CA (2) CA2667030C (fr)
DK (1) DK2091965T3 (fr)
ES (4) ES2545817T3 (fr)
HK (4) HK1131169A1 (fr)
IL (4) IL198186A (fr)
MX (1) MX2009004147A (fr)
PL (1) PL2091965T3 (fr)
PT (1) PT2091965E (fr)
RU (1) RU2469044C2 (fr)
SG (2) SG10201502098YA (fr)
WO (1) WO2008047473A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101175862A (zh) 2005-02-10 2008-05-07 肿瘤疗法科学股份有限公司 诊断膀胱癌的方法
MX2010002018A (es) * 2007-08-20 2010-05-27 Oncotherapy Science Inc Peptido de cdh3 y agente medicinal que comprende al mismo.
US8975086B2 (en) 2008-08-28 2015-03-10 Oncotherapy Science, Inc. Method for treating or preventing bladder cancer using the DEPDC1 polypeptide
AU2010219951A1 (en) * 2009-03-04 2011-08-25 Oncotherapy Science, Inc. VANGL1 peptides and vaccines including the same
WO2012032763A1 (fr) * 2010-09-07 2012-03-15 Oncotherapy Science, Inc. Peptides vangl1 et vaccins les contenant
US9458447B2 (en) 2011-08-12 2016-10-04 Oncotherapy Science, Inc. MPHOSPH1 peptides and vaccines including the same
JP2013058294A (ja) * 2011-09-09 2013-03-28 Toshiba Corp 磁気記録媒体及び磁気記録媒体の製造方法
SG11201404991YA (en) 2012-02-23 2014-09-26 Stage Cell Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
CN104168917A (zh) * 2012-03-09 2014-11-26 肿瘤疗法科学股份有限公司 含有肽的医药组合物
JP6041297B2 (ja) * 2012-08-24 2016-12-07 国立大学法人山口大学 犬リンパ腫の診断方法及び診断キット
MY177482A (en) * 2013-03-13 2020-09-16 Zhong Li Microvesicle and method for producing the same
PT3132247T (pt) 2014-04-16 2021-11-03 Juno Therapeutics Gmbh Métodos, kits e aparelho para ampliar uma população de células
CA3116265A1 (fr) * 2014-10-07 2016-04-14 Cytlimic Inc. Peptide derive de hsp70, et procede de fabrication de composition pharmaceutique, inducteur d'immunite, et cellule presentatrice d'antigene permettant le traitement ou la prevention du cancer l'utilisant
JP6781508B2 (ja) * 2014-11-18 2020-11-04 塩野義製薬株式会社 安定化されたペプチド組成物
RU2714117C2 (ru) 2015-03-09 2020-02-11 Ситлимик Инк. Пептид, полученный из gpc3, фармацевтическая композиция для лечения или предотвращения рака с его использованием, индуктор иммунитета и способ получения антиген-презентирующих клеток
EP3797794A1 (fr) 2015-04-07 2021-03-31 Cytlimic Inc. Médicament comprenant un agoniste au recepteur toll like 3 et une proteine lag-3
AU2016306527B2 (en) * 2015-08-12 2022-03-17 Oncotherapy Science, Inc. DEPDC1-derived peptide and vaccine containing same
EP3360885A4 (fr) * 2015-10-08 2019-04-24 Oncotherapy Science, Inc. Peptide dérivé de mphosph1 et vaccin le contenant
MA45488A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés, kits et appareil de culture de cellules
EP3365453A2 (fr) 2015-10-22 2018-08-29 Juno Therapeutics GmbH Procédés, kits, agents et appareils de transduction
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
WO2018070069A1 (fr) 2016-10-11 2018-04-19 サイトリミック株式会社 Médicament
WO2018092754A1 (fr) * 2016-11-18 2018-05-24 Oncotherapy Science, Inc. Peptides d'épitopes de depdc1 pour des cellules th1 et vaccins les contenant
WO2018092755A1 (fr) * 2016-11-18 2018-05-24 Oncotherapy Science, Inc. Peptides d'épitope de mphosph1 pour des cellules th1 et vaccins les contenant
WO2018094569A1 (fr) * 2016-11-22 2018-05-31 深圳华大基因研究院 Polypeptide et son application
MX2019008878A (es) 2017-01-25 2020-02-13 Ose Immunotherapeutics Metodo para fabricar una emulsion estable para suministro de peptidos.
WO2018197949A1 (fr) 2017-04-27 2018-11-01 Juno Therapeutics Gmbh Reactifs particulaires oligomères et leurs méthodes d'utilisation
MX2020000413A (es) * 2017-07-12 2020-09-28 Nouscom Ag Una vacuna universal basada en neoantigenos de tumor compartidos para prevencion y tratamiento de canceres inestables de microsatelite (msi).
BR112020011620A2 (pt) * 2017-12-13 2020-12-08 Inovio Pharmaceuticals, Inc. Vacinas de câncer com alvo lemd1 e usos das mesmas
CN109932510B (zh) * 2017-12-18 2022-07-12 天津云检医学检验所有限公司 一种宫颈癌生物标志物及其检测试剂盒
CN112142824B (zh) * 2019-06-27 2022-03-11 深圳市东贵博康生化科技有限公司 具有诱导细胞毒性t淋巴细胞能力的多肽及其应用
WO2021060343A1 (fr) * 2019-09-24 2021-04-01 オンコセラピー・サイエンス株式会社 Récepteur de lymphocytes t exprimé par des lymphocytes t humains qui reconnaissent un peptide dérivé d'urlc10 ou un peptide dérivé de depdc1

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
EP1018344A3 (fr) 1991-08-26 2000-09-20 Epimmune, Inc. Epitopes du virus de l'hépatite B induisant une réponse CTL rétrécie par HLA
ZA926441B (en) * 1991-08-26 1993-06-07 Cytel Corp HLA-restricted hepatitis B virus CTL epitopes.
EP0689455A4 (fr) * 1993-03-11 1997-07-23 Univ Southern California Strategies therapeutiques pour le traitement d'infections virales groupees immuno-infectieuses
US5679647A (en) 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US5804566A (en) 1993-08-26 1998-09-08 The Regents Of The University Of California Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides
US5739118A (en) 1994-04-01 1998-04-14 Apollon, Inc. Compositions and methods for delivery of genetic material
US5736524A (en) 1994-11-14 1998-04-07 Merck & Co.,. Inc. Polynucleotide tuberculosis vaccine
US5922687A (en) 1995-05-04 1999-07-13 Board Of Trustees Of The Leland Stanford Junior University Intracellular delivery of nucleic acids using pressure
US20030198642A1 (en) 1995-08-03 2003-10-23 Johannes J. Geuze Cell derived antigen presenting vesicles
US5853719A (en) 1996-04-30 1998-12-29 Duke University Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
WO1998004720A1 (fr) 1996-07-26 1998-02-05 Sloan-Kettering Institute For Cancer Research Procedes et reactifs destines a l'immunisation genetique
FR2766205B1 (fr) 1997-07-16 2002-08-30 Inst Nat Sante Rech Med Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede
US7001999B1 (en) 1998-04-15 2006-02-21 Ludwig Institute For Cancer Research Tumor associated nucleic acids and uses therefor
ATE399179T1 (de) * 1998-09-30 2008-07-15 Corixa Corp Zusammensetzungen und verfahren für wt1- spezifische immunotherapie
US20050123938A1 (en) 1999-01-06 2005-06-09 Chondrogene Limited Method for the detection of osteoarthritis related gene transcripts in blood
US20040241726A1 (en) 1999-01-06 2004-12-02 Chondrogene Limited Method for the detection of allergies related gene transcripts in blood
US6291663B1 (en) 1999-03-03 2001-09-18 Board Of Trustees Of The University Of Arkansas TADG-12: a novel transmembrane serine protease overexpressed in a ovarian carcinoma
US7030215B2 (en) * 1999-03-24 2006-04-18 Sangamo Biosciences, Inc. Position dependent recognition of GNN nucleotide triplets by zinc fingers
JP2003518364A (ja) * 1999-05-28 2003-06-10 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ 乳癌、胃癌および前立腺癌関連抗原ならびにそれらの使用
ATE353366T1 (de) 2000-08-22 2007-02-15 Agensys Inc Nukleinsäure und protein, genannt 158p1d7, für die behandlung und erkennung von blasenkrebs und anderen krebsarten
WO2002031111A2 (fr) 2000-10-12 2002-04-18 Hyseq, Inc. Acides nucleiques et polypeptides
EP1911461B1 (fr) * 2000-10-19 2011-12-07 Epimmune Inc. Peptides de liaisons HLA de classe I et II et leurs utilisations
AU2002226030A1 (en) * 2000-12-04 2002-06-18 Argonex Pharmaceuticals Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
US7919467B2 (en) 2000-12-04 2011-04-05 Immunotope, Inc. Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
US20040142325A1 (en) 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
KR20040077928A (ko) * 2002-01-31 2004-09-07 와이어쓰 아그레카나제 분자
WO2003083074A2 (fr) 2002-03-28 2003-10-09 Idec Pharmaceuticals Corporation Nouvelles cibles geniques et ligands se liant a celles-ci pour le traitement et le diagnostic de carcinomes du colon
US20060024692A1 (en) 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
WO2005007090A2 (fr) 2003-07-03 2005-01-27 President And Fellows Of Harvard College Inhibiteurs de la voie de signalisation des map kinases
CA2580412A1 (fr) 2004-09-13 2006-03-23 Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services Preparations comprenant des recepteurs cellulaires t et methodes d'utilisation de ces preparations
CN101175862A (zh) 2005-02-10 2008-05-07 肿瘤疗法科学股份有限公司 诊断膀胱癌的方法
JP2006302684A (ja) 2005-04-21 2006-11-02 D D K Ltd カードコネクタ
EP2295571A1 (fr) 2005-07-27 2011-03-16 Oncotherapy Science, Inc. Procédé de diagnostic du cancer pulmonaire à petites cellules
CN101287831B (zh) 2005-09-13 2013-05-15 国立大学法人三重大学 T细胞受体和编码该受体的核酸
EP1938104A2 (fr) 2005-10-17 2008-07-02 Institute for Systems Biology Glycoproteines derivees de tissus et du serum et leurs methodes d'utilisation
TWM336439U (en) * 2008-02-14 2008-07-11 Optivision Technology Inc Diffuser capable of light condensing
US8975086B2 (en) 2008-08-28 2015-03-10 Oncotherapy Science, Inc. Method for treating or preventing bladder cancer using the DEPDC1 polypeptide
US9458447B2 (en) 2011-08-12 2016-10-04 Oncotherapy Science, Inc. MPHOSPH1 peptides and vaccines including the same

Also Published As

Publication number Publication date
DK2091965T3 (da) 2013-08-05
US20150231222A1 (en) 2015-08-20
AU2007311395B2 (en) 2013-02-21
MX2009004147A (es) 2009-06-15
KR20140057681A (ko) 2014-05-13
CN102850435B (zh) 2016-02-17
EP2695895A1 (fr) 2014-02-12
US9017688B2 (en) 2015-04-28
US20130129759A1 (en) 2013-05-23
ES2415958T3 (es) 2013-07-29
KR101543622B1 (ko) 2015-08-11
CN102850434B (zh) 2016-04-13
JP2013116115A (ja) 2013-06-13
KR20140104057A (ko) 2014-08-27
IL198186A (en) 2017-05-29
EP2476699A3 (fr) 2013-11-27
JP5339292B2 (ja) 2013-11-13
EP2091965A4 (fr) 2011-02-16
HK1171025A1 (en) 2013-03-15
HK1171026A1 (en) 2013-03-15
EP2091965B9 (fr) 2013-09-25
EP2476697A2 (fr) 2012-07-18
US20100028373A1 (en) 2010-02-04
KR101527473B1 (ko) 2015-06-17
US9545437B2 (en) 2017-01-17
CN102850434A (zh) 2013-01-02
RU2469044C2 (ru) 2012-12-10
US20120288514A1 (en) 2012-11-15
KR20090083378A (ko) 2009-08-03
US20120282286A1 (en) 2012-11-08
EP2476699B1 (fr) 2015-06-17
US8557955B2 (en) 2013-10-15
WO2008047473A1 (fr) 2008-04-24
KR101454287B1 (ko) 2014-11-04
EP2687540A1 (fr) 2014-01-22
ES2545457T3 (es) 2015-09-11
IL222925A0 (en) 2012-12-31
IL216712A0 (en) 2012-01-31
CN101568550B (zh) 2012-12-26
IL216713A0 (en) 2012-01-31
CN101568550A (zh) 2009-10-28
SG175566A1 (en) 2011-11-28
KR20150015042A (ko) 2015-02-09
EP2476698B1 (fr) 2015-06-17
BRPI0717651A2 (pt) 2013-12-24
IL216712A (en) 2017-07-31
EP2476698A2 (fr) 2012-07-18
EP2476699A2 (fr) 2012-07-18
EP2476698A3 (fr) 2013-11-27
EP2687541A1 (fr) 2014-01-22
KR101493773B1 (ko) 2015-03-03
RU2009118432A (ru) 2010-11-27
US8552146B2 (en) 2013-10-08
EP2476697B1 (fr) 2015-06-17
EP2476697A3 (fr) 2013-11-27
CN105693843A (zh) 2016-06-22
CA2915560A1 (fr) 2008-04-24
CA2667030C (fr) 2016-03-15
PL2091965T3 (pl) 2013-10-31
CA2667030A1 (fr) 2008-04-24
CN102850433B (zh) 2016-03-02
US8653234B2 (en) 2014-02-18
EP2091965B1 (fr) 2013-05-15
PT2091965E (pt) 2013-06-11
JP2010506826A (ja) 2010-03-04
EP2091965A1 (fr) 2009-08-26
ES2545818T3 (es) 2015-09-16
HK1171024A1 (en) 2013-03-15
CN102850435A (zh) 2013-01-02
ES2545817T3 (es) 2015-09-16
SG10201502098YA (en) 2015-05-28
CN102850433A (zh) 2013-01-02
AU2007311395A1 (en) 2008-04-24
IL198186A0 (en) 2011-08-01

Similar Documents

Publication Publication Date Title
IL222925A0 (en) Peptide vaccines for cancers expressing mphosph1 or depdc1 polypeptides
IL221062A0 (en) Stitched polypeptides
GB0721686D0 (en) Polypeptides
PL2325305T3 (pl) Szczepionki peptydowe na nowotwory płuc z ekspresją polipeptydów TTK, URLC10 lub KOC1
ZA200810738B (en) Polypeptide
GB0712670D0 (en) Isolated peptides and uses thereof
GB0708376D0 (en) Novel polypeptides and uses thereof
ZA201000283B (en) Reinigung pegylierter polypeptide
GB0723712D0 (en) Peptides
EP2123666A4 (fr) Peptide
EP2162740A4 (fr) Identification de séquences de peptides modifiées oxydativement dans le protéome
GB0725201D0 (en) Peptide fusion proteins
GB0623539D0 (en) Polypeptides
EP2188305A4 (fr) Peptides modifiés présentant des effets améliorateurs de toxines
GB0703945D0 (en) Peptide
IL203073A0 (en) Modified growth hormone polypeptides
IL197675A0 (en) Peptides
EP2097439A4 (fr) Nouveaux peptides
GB0708529D0 (en) Peptide standards
GB0705251D0 (en) Peptides
GB0705115D0 (en) Peptides
EP2123751A4 (fr) Nouveau peptide
GB0609920D0 (en) Peptides
GB0625176D0 (en) Peptides
GB0618512D0 (en) Peptides

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20221016