HK1130264A1 - Compositions and their uses directed to diacylglycerol acyltransferase 1 - Google Patents
Compositions and their uses directed to diacylglycerol acyltransferase 1Info
- Publication number
- HK1130264A1 HK1130264A1 HK09110220.2A HK09110220A HK1130264A1 HK 1130264 A1 HK1130264 A1 HK 1130264A1 HK 09110220 A HK09110220 A HK 09110220A HK 1130264 A1 HK1130264 A1 HK 1130264A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- compositions
- diacylglycerol acyltransferase
- uses directed
- directed
- acyltransferase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/0102—Diacylglycerol O-acyltransferase (2.3.1.20)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82151106P | 2006-08-04 | 2006-08-04 | |
PCT/US2007/075297 WO2008019351A2 (fr) | 2006-08-04 | 2007-08-06 | Compositions et leurs utilisations dirigées sur la diacylglycérol acyltransférase 1 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1130264A1 true HK1130264A1 (en) | 2009-12-24 |
Family
ID=39033610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09110220.2A HK1130264A1 (en) | 2006-08-04 | 2009-11-04 | Compositions and their uses directed to diacylglycerol acyltransferase 1 |
Country Status (5)
Country | Link |
---|---|
US (2) | US8003620B2 (fr) |
EP (1) | EP2057177B1 (fr) |
ES (1) | ES2397661T3 (fr) |
HK (1) | HK1130264A1 (fr) |
WO (1) | WO2008019351A2 (fr) |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6867039B2 (en) | 2001-05-25 | 2005-03-15 | Isis Pharmaceuticals, Inc. | Antisense modulation of dual specific phosphatase 5 expression |
US6582908B2 (en) | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
US5801154A (en) | 1993-10-18 | 1998-09-01 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of multidrug resistance-associated protein |
US5708160A (en) | 1995-04-26 | 1998-01-13 | The National Research Council | HSP-60 genomic locus and primers for species identification |
WO2000078961A1 (fr) | 1999-06-23 | 2000-12-28 | Genentech, Inc. | Polypeptides secretes et transmembranaires et acides nucleiques codant pour ces polypeptides |
US20030228597A1 (en) | 1998-04-13 | 2003-12-11 | Cowsert Lex M. | Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation |
US20030167483A1 (en) | 1998-06-24 | 2003-09-04 | Farese Robert V. | Diacylglycerol O-acyltransferase |
US6344548B1 (en) | 1998-06-24 | 2002-02-05 | The Regents Of The University Of California | Diacylglycerol o-acyltransferase |
ATE406448T1 (de) | 1998-06-24 | 2008-09-15 | David Gladstone Inst | Diacylglycerin o-acyltransferase |
US20030100480A1 (en) | 1998-06-24 | 2003-05-29 | Smith Steven J. | Methods and compositions for modulating sebaceous glands |
US20030154504A1 (en) * | 1998-06-24 | 2003-08-14 | Farese Robert V. | Methods and compositions for modulating carbohydrate metabolism |
US7135617B2 (en) | 1998-07-02 | 2006-11-14 | Calgene Llc | Diacylglycerol acyl transferase proteins |
ATE442435T1 (de) | 1998-07-02 | 2009-09-15 | Calgene Llc | Diacylglyzerin-acyltransferase proteine |
US6100077A (en) | 1998-10-01 | 2000-08-08 | The Trustees Of Columbia University In The City Of New York | Isolation of a gene encoding diacylglycerol acyltransferase |
US5998148A (en) | 1999-04-08 | 1999-12-07 | Isis Pharmaceuticals Inc. | Antisense modulation of microtubule-associated protein 4 expression |
AU6802801A (en) | 2000-03-01 | 2001-09-24 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA2403946A1 (fr) | 2000-04-05 | 2001-10-18 | Incyte Genomics, Inc. | Genes exprimes lors de la differenciation de cellules spumeuses |
US6444427B1 (en) | 2000-07-11 | 2002-09-03 | The Regents Of The University Of California | Polymorphisms in a diacylglycerol acyltransferase gene, and methods of use thereof |
WO2002008260A2 (fr) | 2000-07-26 | 2002-01-31 | Stanford University | Proteine bstp-ecg1 et reactifs associes et procedes d'utilisation de ceux-ci |
DE01992795T1 (de) | 2000-10-31 | 2004-12-16 | Michel Alphonse Julien Georges | Marker-unterstützte auswahl von rindvieh für verbesserte milchproduktion unter verwendung des diacylglycerin-acyltransferase-gens dgat1 |
MXPA01012317A (es) | 2000-12-28 | 2002-07-22 | Warner Lambert Co | Prueba de aciltransferasa del diacilglicerol (dgat). |
US6440738B1 (en) | 2001-02-08 | 2002-08-27 | Isis Pharmaceuticals, Inc. | Antisense modulation of casein kinase 2-beta expression |
US20020119138A1 (en) | 2001-02-26 | 2002-08-29 | Sylvaine Cases | Diacylglycerol o-acyltransferase 2alpha (DGAT2alpha) |
US7045326B2 (en) | 2001-02-23 | 2006-05-16 | The Regents Of The University Of California | Mono- and diacylglycerol acyltransferases and methods of use thereof |
US20030161831A1 (en) | 2001-02-23 | 2003-08-28 | Sylvaine Cases | Mono-and diacylglycerol acyltransferases and methods of use thereof |
JP2002284741A (ja) | 2001-03-23 | 2002-10-03 | Kitasato Inst:The | ローズリピン誘導体 |
US6835556B2 (en) | 2001-04-12 | 2004-12-28 | Pharmacia Ab | Protein cluster V |
WO2002086085A2 (fr) | 2001-04-24 | 2002-10-31 | Bayer Corporation | Anticorps timp-1 humains |
US20040234986A1 (en) | 2001-07-06 | 2004-11-25 | Hans-Rudolf Fries | Method of testing a mammal for its predisposition for fat content of milk and/ or its predisposition for meat marbling |
EP1308459A3 (fr) | 2001-11-05 | 2003-07-09 | Research Association for Biotechnology | Séquences d'ADN complementaires pleine longueur |
AU2002360531A1 (en) | 2001-12-10 | 2003-06-23 | Millennium Pharmaceuticals, Inc. | Methods and compositions to treat cardiovascular disease using 1419, 58765 and 2201 |
WO2003052090A1 (fr) | 2001-12-17 | 2003-06-26 | E. I. Du Pont De Nemours And Company | Phospholipide : diacylglycerol acyltransferases |
US20030170691A1 (en) | 2001-12-19 | 2003-09-11 | Millennium Pharmaceuticals, Inc. | Human diacylglycerol acyltransferase 2 (DGAT2) family members and uses therefor |
US6847366B2 (en) * | 2002-03-01 | 2005-01-25 | Hewlett-Packard Development Company, L.P. | System and method utilizing multiple processes to render graphical data |
EP1496838B1 (fr) | 2002-03-12 | 2010-11-03 | Merck Sharp & Dohme Corp. | Amides substitues |
US7105526B2 (en) | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
BR0313536A (pt) | 2002-07-31 | 2005-06-14 | Monsanto Technology Llc | Sequencias de ácido nucléico de diacilglicerol acetiltransferase e produtos associados |
JP2006507841A (ja) | 2002-11-14 | 2006-03-09 | ダーマコン, インコーポレイテッド | 機能的siRNAおよび超機能的siRNA |
US20040122033A1 (en) | 2002-12-10 | 2004-06-24 | Nargund Ravi P. | Combination therapy for the treatment of obesity |
US20040185559A1 (en) * | 2003-03-21 | 2004-09-23 | Isis Pharmaceuticals Inc. | Modulation of diacylglycerol acyltransferase 1 expression |
US7795283B2 (en) * | 2004-12-14 | 2010-09-14 | Astrazeneca Ab | Oxadiazole derivative as DGAT inhibitors |
-
2007
- 2007-08-06 ES ES07813825T patent/ES2397661T3/es active Active
- 2007-08-06 US US11/834,640 patent/US8003620B2/en not_active Expired - Fee Related
- 2007-08-06 WO PCT/US2007/075297 patent/WO2008019351A2/fr active Application Filing
- 2007-08-06 EP EP07813825A patent/EP2057177B1/fr not_active Not-in-force
-
2009
- 2009-11-04 HK HK09110220.2A patent/HK1130264A1/en not_active IP Right Cessation
-
2011
- 2011-07-06 US US13/177,457 patent/US8455456B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20090054359A1 (en) | 2009-02-26 |
WO2008019351A2 (fr) | 2008-02-14 |
EP2057177A4 (fr) | 2009-10-28 |
US8003620B2 (en) | 2011-08-23 |
EP2057177A2 (fr) | 2009-05-13 |
WO2008019351A3 (fr) | 2008-10-16 |
EP2057177B1 (fr) | 2012-11-21 |
US20120029050A1 (en) | 2012-02-02 |
WO2008019351A8 (fr) | 2011-12-29 |
US8455456B2 (en) | 2013-06-04 |
ES2397661T3 (es) | 2013-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20160806 |