ATE406448T1 - Diacylglycerin o-acyltransferase - Google Patents
Diacylglycerin o-acyltransferaseInfo
- Publication number
- ATE406448T1 ATE406448T1 AT99930624T AT99930624T ATE406448T1 AT E406448 T1 ATE406448 T1 AT E406448T1 AT 99930624 T AT99930624 T AT 99930624T AT 99930624 T AT99930624 T AT 99930624T AT E406448 T1 ATE406448 T1 AT E406448T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- well
- acid compositions
- applications
- diacylglycerin
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000002148 Diacylglycerol O-acyltransferase Human genes 0.000 abstract 1
- 108010001348 Diacylglycerol O-acyltransferase Proteins 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 150000003626 triacylglycerols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Child & Adolescent Psychology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/103,754 US6344548B1 (en) | 1998-06-24 | 1998-06-24 | Diacylglycerol o-acyltransferase |
| US10777198P | 1998-11-09 | 1998-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE406448T1 true ATE406448T1 (de) | 2008-09-15 |
Family
ID=26800810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99930624T ATE406448T1 (de) | 1998-06-24 | 1999-06-23 | Diacylglycerin o-acyltransferase |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1090026B1 (de) |
| AT (1) | ATE406448T1 (de) |
| AU (1) | AU779423B2 (de) |
| CA (1) | CA2330363C (de) |
| DE (1) | DE69939426D1 (de) |
| WO (1) | WO1999067268A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000066749A1 (en) * | 1999-05-04 | 2000-11-09 | Cargill, Incorporated | Plant acyltransferases |
| US6995301B1 (en) | 1999-05-04 | 2006-02-07 | Cargill, Incorporated | Plant acyltransferases |
| US6552250B1 (en) | 2000-06-14 | 2003-04-22 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food | Diacylglycerol O-acyltransferase |
| US6444427B1 (en) * | 2000-07-11 | 2002-09-03 | The Regents Of The University Of California | Polymorphisms in a diacylglycerol acyltransferase gene, and methods of use thereof |
| US20020119138A1 (en) | 2001-02-26 | 2002-08-29 | Sylvaine Cases | Diacylglycerol o-acyltransferase 2alpha (DGAT2alpha) |
| US7045326B2 (en) | 2001-02-23 | 2006-05-16 | The Regents Of The University Of California | Mono- and diacylglycerol acyltransferases and methods of use thereof |
| CA2453001C (en) * | 2001-07-06 | 2011-05-24 | Arbeitsgemeinschaft Deutscher Rinderzuchter E.V. | Method of testing a mammal for its predisposition for fat content of milk and/or its predisposition for meat marbling |
| AU2003259682A1 (en) | 2002-07-31 | 2004-02-16 | Monsanto Technology, Llc | Diacylglycerol acyltransferase nucleic acid sequences and associated products |
| US20040185559A1 (en) * | 2003-03-21 | 2004-09-23 | Isis Pharmaceuticals Inc. | Modulation of diacylglycerol acyltransferase 1 expression |
| AR044152A1 (es) | 2003-05-09 | 2005-08-24 | Bayer Corp | Derivados de alquilarilo, metodo de preparacion y uso para el tratamiento de la obesidad |
| AU2007272316B2 (en) | 2006-07-14 | 2014-01-09 | Commonwealth Scientific And Industrial Research Organisation | Altering the fatty acid composition of rice |
| US8003620B2 (en) | 2006-08-04 | 2011-08-23 | Isis Pharmaceuticals, Inc. | Compositions and their uses directed to diacylglycerol acyltransferase 1 |
| NZ554114A (en) * | 2007-04-23 | 2010-01-29 | Agres Ltd | Plants with an increased ratio of oleosin to TAG synthesising enzymes |
| AU2009273755A1 (en) | 2008-07-21 | 2010-01-28 | Commonwealth Scientific And Industrial Research Organisation | Improved vegetable oils and uses therefor |
| AU2009273754B2 (en) | 2008-07-21 | 2016-07-14 | Commonwealth Scientific And Industrial Research Organisation | Improved cottonseed oil and uses |
| MA34097B1 (fr) | 2010-03-30 | 2013-03-05 | Novartis Ag | Utilisations d'inhibiteurs de dgat1 |
| EP2585589B1 (de) | 2010-06-28 | 2017-06-21 | Commonwealth Scientific and Industrial Research Organisation | Verfahren zur herstellung von lipiden |
| US11639507B2 (en) | 2011-12-27 | 2023-05-02 | Commonwealth Scientific And Industrial Research Organisation | Processes for producing lipids |
| UA119739C2 (uk) | 2011-12-27 | 2019-08-12 | Коммонвелт Сайнтіфік Енд Індастріел Рісерч Організейшн | Метод отримання ліпідів |
| US8809026B2 (en) | 2011-12-27 | 2014-08-19 | Commonwealth Scientific And Industrial Research Organisation | Processes for producing lipids |
| US10323209B2 (en) | 2012-04-25 | 2019-06-18 | Commonwealth Scientific And Industrial Research Organisation | High oleic acid oils |
| EP4303288B1 (de) | 2014-07-07 | 2025-09-10 | Nuseed Global Innovation Ltd | Verfahren zur herstellung von industriellen produkten aus pflanzlichen lipiden |
| US11020429B2 (en) | 2015-11-05 | 2021-06-01 | Juno Therapeutics, Inc. | Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy |
| CN110462043A (zh) | 2016-09-02 | 2019-11-15 | 联邦科学技术研究组织 | 具有修饰的性状的植物 |
| CA3093970A1 (en) | 2018-03-16 | 2019-09-19 | Anji Pharmaceuticals Inc. | Compositions and methods for treating severe constipation |
| WO2023085931A1 (en) | 2021-11-11 | 2023-05-19 | Koninklijke Nederlandse Akademie Van Wetenschappen | Hepatic organoids |
-
1999
- 1999-06-23 DE DE69939426T patent/DE69939426D1/de not_active Expired - Lifetime
- 1999-06-23 WO PCT/US1999/014245 patent/WO1999067268A1/en not_active Ceased
- 1999-06-23 AT AT99930624T patent/ATE406448T1/de not_active IP Right Cessation
- 1999-06-23 CA CA002330363A patent/CA2330363C/en not_active Expired - Fee Related
- 1999-06-23 EP EP99930624A patent/EP1090026B1/de not_active Expired - Lifetime
- 1999-06-23 AU AU47124/99A patent/AU779423B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU4712499A (en) | 2000-01-10 |
| CA2330363A1 (en) | 1999-12-29 |
| EP1090026B1 (de) | 2008-08-27 |
| CA2330363C (en) | 2009-10-20 |
| AU779423B2 (en) | 2005-01-20 |
| DE69939426D1 (de) | 2008-10-09 |
| EP1090026A4 (de) | 2004-05-06 |
| WO1999067268A1 (en) | 1999-12-29 |
| EP1090026A1 (de) | 2001-04-11 |
| WO1999067268A9 (en) | 2000-03-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE376054T1 (de) | Diacylglyzerin o-acyltransferase | |
| ATE406448T1 (de) | Diacylglycerin o-acyltransferase | |
| BR9910251A (pt) | Estimulação hematopoiética | |
| FI945793L (fi) | DNA-sekvenssejä, joita käytetään rekombinanttisen ihmis-BSSL/CEL:n valmistuksessa transgeenisissä ei-ihmisnisäkkäissä, ja valmistettu BSSL/CEL, jota käytetään pikkulasten formulaateissa | |
| GR3033630T3 (en) | Gene expression elements and the production of chimeric mouse-human antibodies. | |
| CA2006473A1 (en) | Improved anti-infective therapy | |
| DE68924026D1 (de) | Biosensor und dessen herstellung. | |
| DE3687646D1 (de) | Biosensor und dessen herstellung. | |
| DE69835367D1 (de) | Gentherapie für gaucher-krankheit | |
| ES2109945T3 (es) | Composiciones y procedimientos para identificar moleculas biologicamente activas. | |
| DE69738581D1 (de) | Menschliche dnase i hyperaktive varianten | |
| AU2003266214A1 (en) | Human coagulation factor vii polypeptides | |
| DE3879975D1 (de) | Demethylavermectine und herstellung dazu. | |
| ID25950A (id) | Katalis-katalis untuk memproduksi aldehid tidak jenuh dan asam karboksilat tidak jenuh dan proses untuk produksi aldehid tidak jenuh dan asam karboksilat tidak jenuh menggunakan katalis | |
| DE69916856T2 (de) | Micropartikeln zur verwendung in nadellosen injektion | |
| TW200407425A (en) | Human coagulation factor VII polypeptides | |
| DE3485826D1 (de) | Herstellung und verwendung polymerer kugeln. | |
| DE69532485D1 (de) | Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung | |
| WO1997009420A3 (en) | Dna sequences coding for a human metalloproteinase and variants thereof | |
| BR0000698A (pt) | 15, 15'-dioxigenases de beta, beta-caroteno | |
| DE69728863D1 (de) | Enzym mit pektin-esterase-aktivität | |
| ITRM930818A0 (it) | Procedimento per la produzione in piante di anticorpi ingegnerizzati, anticorpi prodotti e loro uso in diagnosi e terapia. | |
| FI954889A0 (fi) | Proteiini, jolla on TPO-aktiviteetti | |
| EP0759976A4 (de) | Die isolierung und herstellung von katalytischen antikörpern mittels phagentechnologie | |
| DK0517756T3 (da) | Vævs-plasminogenaktivator med fibrinspecifikke egenskaber |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |