HK1130252A1 - Aminoacyl prodrug derivatives and medicaments for the treatment of thromboembolitic disorders - Google Patents
Aminoacyl prodrug derivatives and medicaments for the treatment of thromboembolitic disordersInfo
- Publication number
- HK1130252A1 HK1130252A1 HK09108129.8A HK09108129A HK1130252A1 HK 1130252 A1 HK1130252 A1 HK 1130252A1 HK 09108129 A HK09108129 A HK 09108129A HK 1130252 A1 HK1130252 A1 HK 1130252A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- treatment
- medicaments
- disorders
- thromboembolitic
- prodrug derivatives
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 239000000651 prodrug Substances 0.000 title abstract 2
- 229940002612 prodrug Drugs 0.000 title abstract 2
- 125000000266 alpha-aminoacyl group Chemical group 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- KGFYHTZWPPHNLQ-AWEZNQCLSA-N rivaroxaban Chemical class S1C(Cl)=CC=C1C(=O)NC[C@@H]1OC(=O)N(C=2C=CC(=CC=2)N2C(COCC2)=O)C1 KGFYHTZWPPHNLQ-AWEZNQCLSA-N 0.000 abstract 1
- 230000009424 thromboembolic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006007146A DE102006007146A1 (de) | 2006-02-16 | 2006-02-16 | Aminoacyl-Prodrugs |
PCT/EP2007/001135 WO2007093328A1 (de) | 2006-02-16 | 2007-02-06 | Aminoacyl-prodrug derivate und arzneimittel zur behandlung von thromboembolischen erkrankungen |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1130252A1 true HK1130252A1 (en) | 2009-12-24 |
Family
ID=38179935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09108129.8A HK1130252A1 (en) | 2006-02-16 | 2009-09-04 | Aminoacyl prodrug derivatives and medicaments for the treatment of thromboembolitic disorders |
Country Status (23)
Country | Link |
---|---|
US (2) | US8101601B2 (xx) |
EP (1) | EP1987026B1 (xx) |
JP (1) | JP5225864B2 (xx) |
KR (1) | KR20080094696A (xx) |
CN (1) | CN101384585B (xx) |
AT (1) | ATE440839T1 (xx) |
AU (1) | AU2007214766B2 (xx) |
BR (1) | BRPI0708064A2 (xx) |
CA (1) | CA2642376C (xx) |
CY (1) | CY1109375T1 (xx) |
DE (2) | DE102006007146A1 (xx) |
DK (1) | DK1987026T3 (xx) |
ES (1) | ES2330689T3 (xx) |
HK (1) | HK1130252A1 (xx) |
HR (1) | HRP20090629T1 (xx) |
IL (1) | IL192987A0 (xx) |
PL (1) | PL1987026T3 (xx) |
PT (1) | PT1987026E (xx) |
RS (1) | RS51190B (xx) |
RU (1) | RU2435768C2 (xx) |
SI (1) | SI1987026T1 (xx) |
WO (1) | WO2007093328A1 (xx) |
ZA (1) | ZA200806891B (xx) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102006039589A1 (de) * | 2006-08-24 | 2008-03-06 | Bayer Healthcare Ag | Aminoacyl-Prodrugs II |
DE102007032347A1 (de) * | 2007-07-11 | 2009-01-15 | Bayer Healthcare Ag | Aminoacyl-Prodrugs |
DE102007032345A1 (de) * | 2007-07-11 | 2009-01-15 | Bayer Healthcare Ag | Aminoacyl-Prodrugs |
CN101875655B (zh) * | 2009-04-28 | 2012-05-09 | 天津药物研究院 | 氨基苯甲酸衍生物及其制备方法和用途 |
US7816355B1 (en) | 2009-04-28 | 2010-10-19 | Apotex Pharmachem Inc | Processes for the preparation of rivaroxaban and intermediates thereof |
US8971019B2 (en) | 2012-03-16 | 2015-03-03 | Avx Corporation | Wet capacitor cathode containing an alkyl-substituted poly(3,4-ethylenedioxythiophene) |
CN102746287B (zh) * | 2012-06-21 | 2014-05-28 | 成都苑东药业有限公司 | 一种恶唑烷酮化合物及其制备方法 |
RU2015112195A (ru) | 2012-12-26 | 2017-01-31 | Уэнбери Лтд. | Альдегидное производное замещенных оксазолидинонов |
PT2895176T (pt) | 2012-12-26 | 2017-01-27 | Wanbury Ltd | Intermediário de rivaroxabano e a sua preparação |
CN114384185A (zh) * | 2022-01-20 | 2022-04-22 | 北京航空航天大学 | 用于检测γ-氨基丁酸含量的试剂在制备诊断静脉流出障碍性疾病的试剂盒中的应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1196414T3 (da) * | 1999-06-25 | 2003-11-24 | Vertex Pharma | Prolægemiddel af carbamathæmmer for IMPDH |
DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
DE10129725A1 (de) * | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
CA2452513A1 (en) * | 2001-07-12 | 2003-01-23 | Pharmacia & Upjohn Company | Amide-containing compound having improved solubility and method of improving the solubility of an amide-containing compound |
US7265140B2 (en) * | 2003-09-23 | 2007-09-04 | Pfizer Inc | Acyloxymethylcarbamate prodrugs of oxazolidinones |
DE10355461A1 (de) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
DE102004002044A1 (de) | 2004-01-15 | 2005-08-04 | Bayer Healthcare Ag | Herstellverfahren |
DE102004062475A1 (de) | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
DE102005047558A1 (de) | 2005-10-04 | 2008-02-07 | Bayer Healthcare Ag | Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen |
DE102006039589A1 (de) * | 2006-08-24 | 2008-03-06 | Bayer Healthcare Ag | Aminoacyl-Prodrugs II |
-
2006
- 2006-02-16 DE DE102006007146A patent/DE102006007146A1/de not_active Withdrawn
-
2007
- 2007-02-06 DK DK07703379T patent/DK1987026T3/da active
- 2007-02-06 CA CA2642376A patent/CA2642376C/en not_active Expired - Fee Related
- 2007-02-06 PT PT07703379T patent/PT1987026E/pt unknown
- 2007-02-06 RU RU2008136769/04A patent/RU2435768C2/ru not_active IP Right Cessation
- 2007-02-06 AT AT07703379T patent/ATE440839T1/de active
- 2007-02-06 AU AU2007214766A patent/AU2007214766B2/en not_active Ceased
- 2007-02-06 EP EP07703379A patent/EP1987026B1/de active Active
- 2007-02-06 BR BRPI0708064-6A patent/BRPI0708064A2/pt not_active IP Right Cessation
- 2007-02-06 ES ES07703379T patent/ES2330689T3/es active Active
- 2007-02-06 RS RSP-2009/0408A patent/RS51190B/sr unknown
- 2007-02-06 DE DE502007001402T patent/DE502007001402D1/de active Active
- 2007-02-06 JP JP2008554638A patent/JP5225864B2/ja not_active Expired - Fee Related
- 2007-02-06 PL PL07703379T patent/PL1987026T3/pl unknown
- 2007-02-06 US US12/224,007 patent/US8101601B2/en not_active Expired - Fee Related
- 2007-02-06 SI SI200730099T patent/SI1987026T1/sl unknown
- 2007-02-06 CN CN2007800055375A patent/CN101384585B/zh not_active Expired - Fee Related
- 2007-02-06 WO PCT/EP2007/001135 patent/WO2007093328A1/de active Application Filing
- 2007-02-06 KR KR1020087020037A patent/KR20080094696A/ko not_active Application Discontinuation
-
2008
- 2008-07-23 IL IL192987A patent/IL192987A0/en unknown
- 2008-08-11 ZA ZA200806891A patent/ZA200806891B/xx unknown
-
2009
- 2009-09-04 HK HK09108129.8A patent/HK1130252A1/xx not_active IP Right Cessation
- 2009-09-18 CY CY20091100964T patent/CY1109375T1/el unknown
- 2009-11-25 HR HR20090629T patent/HRP20090629T1/hr unknown
-
2011
- 2011-12-16 US US13/328,532 patent/US8334284B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2007214766A1 (en) | 2007-08-23 |
RU2435768C2 (ru) | 2011-12-10 |
BRPI0708064A2 (pt) | 2011-05-17 |
SI1987026T1 (sl) | 2010-01-29 |
CA2642376A1 (en) | 2007-08-23 |
HRP20090629T1 (hr) | 2010-01-31 |
EP1987026A1 (de) | 2008-11-05 |
PT1987026E (pt) | 2009-10-30 |
RU2008136769A (ru) | 2010-03-27 |
US20120088761A1 (en) | 2012-04-12 |
IL192987A0 (en) | 2009-02-11 |
ES2330689T3 (es) | 2009-12-14 |
ATE440839T1 (de) | 2009-09-15 |
JP5225864B2 (ja) | 2013-07-03 |
US8334284B2 (en) | 2012-12-18 |
CY1109375T1 (el) | 2014-07-02 |
PL1987026T3 (pl) | 2010-03-31 |
RS51190B (sr) | 2010-10-31 |
AU2007214766B2 (en) | 2013-05-02 |
EP1987026B1 (de) | 2009-08-26 |
DE102006007146A1 (de) | 2007-08-23 |
US20110034453A1 (en) | 2011-02-10 |
ZA200806891B (en) | 2010-02-24 |
DK1987026T3 (da) | 2009-11-02 |
US8101601B2 (en) | 2012-01-24 |
CA2642376C (en) | 2014-08-12 |
CN101384585B (zh) | 2012-09-26 |
DE502007001402D1 (de) | 2009-10-08 |
CN101384585A (zh) | 2009-03-11 |
KR20080094696A (ko) | 2008-10-23 |
WO2007093328A1 (de) | 2007-08-23 |
JP2009526788A (ja) | 2009-07-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20180206 |