HK1126390A1 - Use of citrulline in the manufacture of a medicament for the correction of arginine deficiency in septic patients - Google Patents
Use of citrulline in the manufacture of a medicament for the correction of arginine deficiency in septic patientsInfo
- Publication number
- HK1126390A1 HK1126390A1 HK09104767.4A HK09104767A HK1126390A1 HK 1126390 A1 HK1126390 A1 HK 1126390A1 HK 09104767 A HK09104767 A HK 09104767A HK 1126390 A1 HK1126390 A1 HK 1126390A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- citrulline
- arginine
- medicament
- correction
- manufacture
- Prior art date
Links
- 239000004475 Arginine Substances 0.000 title abstract 5
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 title abstract 5
- RHGKLRLOHDJJDR-BYPYZUCNSA-N L-citrulline Chemical compound NC(=O)NCCC[C@H]([NH3+])C([O-])=O RHGKLRLOHDJJDR-BYPYZUCNSA-N 0.000 title abstract 4
- 229960002173 citrulline Drugs 0.000 title abstract 3
- RHGKLRLOHDJJDR-UHFFFAOYSA-N Ndelta-carbamoyl-DL-ornithine Natural products OC(=O)C(N)CCCNC(N)=O RHGKLRLOHDJJDR-UHFFFAOYSA-N 0.000 title abstract 2
- 235000013477 citrulline Nutrition 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 230000007812 deficiency Effects 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 238000012423 maintenance Methods 0.000 abstract 2
- 208000030090 Acute Disease Diseases 0.000 abstract 1
- 208000017667 Chronic Disease Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 201000006549 dyspepsia Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000001771 impaired effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000036186 satiety Effects 0.000 abstract 1
- 235000019627 satiety Nutrition 0.000 abstract 1
- 230000009469 supplementation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Obesity (AREA)
- Polymers & Plastics (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78933006P | 2006-04-04 | 2006-04-04 | |
US74749306P | 2006-05-17 | 2006-05-17 | |
PCT/US2007/008143 WO2007114903A2 (en) | 2006-04-04 | 2007-04-02 | Treatments using citrulline |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1126390A1 true HK1126390A1 (en) | 2009-09-04 |
Family
ID=38461725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK09104767.4A HK1126390A1 (en) | 2006-04-04 | 2009-05-26 | Use of citrulline in the manufacture of a medicament for the correction of arginine deficiency in septic patients |
Country Status (13)
Country | Link |
---|---|
US (1) | US20090291877A1 (ru) |
EP (3) | EP2612666A3 (ru) |
JP (2) | JP2009533342A (ru) |
CN (1) | CN102935231A (ru) |
AU (1) | AU2007233371B2 (ru) |
BR (1) | BRPI0710044A2 (ru) |
CA (2) | CA2648126C (ru) |
HK (1) | HK1126390A1 (ru) |
IL (1) | IL194202A0 (ru) |
MX (1) | MX2008012723A (ru) |
RU (1) | RU2444355C2 (ru) |
WO (1) | WO2007114903A2 (ru) |
ZA (1) | ZA200809393B (ru) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2913885B1 (fr) * | 2007-03-22 | 2012-07-20 | Univ Paris Descartes | Utilisation de la citrulline pour le traitement des pathologies liees a une augmentation de la carbonylation des proteines |
CA2702045C (en) | 2007-10-10 | 2017-07-25 | Kyowa Hakko Bio Co., Ltd. | Rapid-acting, blood-arginine-level-increasable oral preparation comprising citrulline and arginine |
ITMI20080567A1 (it) * | 2008-04-02 | 2009-10-03 | Androsystems Srl | L-citrullina per il trattamento della disfunzione endoteliale e della disfunzione erettile. |
CN102215837B (zh) | 2008-09-19 | 2014-04-30 | 雀巢产品技术援助有限公司 | 预防和/或减轻癌性肿瘤的骨髓毒性的营养支持 |
CN105876780A (zh) | 2008-09-19 | 2016-08-24 | 雀巢产品技术援助有限公司 | 抗癌治疗中的免疫系统营养支持 |
US20100179089A1 (en) * | 2009-01-13 | 2010-07-15 | Deutz Nicolaas E P | Compositions and Methods to Manage the Inflammatory Basis of Chronic Disease Conditions and Maintain an Optimal Immune Response in Elderly |
WO2011019641A2 (en) * | 2009-08-13 | 2011-02-17 | Nestec S.A. | Nutritional compositions including exogenous nucleotides |
FR2970414B1 (fr) * | 2011-01-14 | 2013-03-22 | Univ Paris Descartes | Action preventive de la citrulline sur le developpement spontane des tumeurs |
US20140037604A1 (en) * | 2011-04-18 | 2014-02-06 | Nestec S.A. | Nutritional compositions comprising alpha-hydroxyisocaproic acid |
JP2013060406A (ja) * | 2011-09-15 | 2013-04-04 | Kyowa Hakko Bio Co Ltd | 脳疲労改善用経口剤 |
WO2013063533A1 (en) * | 2011-10-26 | 2013-05-02 | Clinical And Herbal Innovations, Inc. | Dietary supplement for vascular health |
US20150025147A1 (en) * | 2012-03-02 | 2015-01-22 | Kyowa Hakko Bio Co., Ltd | Enhancer for eating activity and/or gastrointestinal activity |
JP6876632B2 (ja) * | 2015-06-29 | 2021-05-26 | バンダービルト・ユニバーシティVanderbilt University | 手術中のシトルリン静脈内投与 |
JP6357625B2 (ja) * | 2015-07-23 | 2018-07-18 | テクノサイエンス株式会社 | 栄養補助食品用の組成物 |
KR102396603B1 (ko) | 2015-09-16 | 2022-05-11 | 원광대학교산학협력단 | 시트룰린을 유효성분으로 함유하는 간 기능 개선용 조성물 |
JP2016121194A (ja) * | 2016-04-05 | 2016-07-07 | 協和発酵バイオ株式会社 | 脳疲労改善用経口剤 |
JP2018119017A (ja) * | 2018-05-16 | 2018-08-02 | テクノサイエンス株式会社 | 栄養補助食品用の組成物 |
EP4142520A1 (en) * | 2020-04-29 | 2023-03-08 | Société des Produits Nestlé S.A. | A nutritional product containing a buffer composition and an amino acid and methods of using such a nutritional product |
CN112868919B (zh) * | 2021-02-25 | 2023-01-17 | 新疆农业大学 | 一种提升公羊精液品质的饲料及其应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4096254A (en) * | 1976-05-10 | 1978-06-20 | Richardson-Merrell Inc. | Method of treating the symptoms of menopause and osteoporosis |
US5411757A (en) * | 1989-11-09 | 1995-05-02 | Buist; Neil R. M. | Palatable balanced amino acid-modified diet |
CA2116684A1 (en) * | 1991-09-27 | 1993-04-01 | Robert G. Kilbourn | Amino acids containing parenteral formulations for the treatment of hypotension and related pathologies |
US5780039A (en) | 1992-04-23 | 1998-07-14 | Novartis Nutrition Ag | Orally-ingestible nutrition compositions having improved palatability |
US5356873A (en) * | 1992-11-05 | 1994-10-18 | Clintec Nutrition Co. | Method for providing nutritional requirements to patients having a chronic inflammation reaction |
US5874471A (en) * | 1997-02-27 | 1999-02-23 | Waugh; William Howard | Orthomolecular medical use of L-citrulline for vasoprotection, relaxative smooth muscle tone and cell protection |
US20010056068A1 (en) * | 1998-03-04 | 2001-12-27 | Kristof Chwalisz | Method of treatment and prevention of nitric oxide deficiency-related disorders with citrulline and citrulline derivatives |
US20020068365A1 (en) | 1998-07-28 | 2002-06-06 | Eric H. Kuhrts | Controlled release nitric oxide producing agents |
CA2348741C (en) * | 1998-10-30 | 2010-04-20 | Nitromed Inc. | Nitrosasted and nitrosylated nonsteroidal antiinflammatory compounds, comositions and methods of use |
ATE308254T1 (de) * | 1998-12-15 | 2005-11-15 | Nestle Sa | Ballaststoffemischung für enterale zusammensetzung |
US20020193342A1 (en) | 2001-05-09 | 2002-12-19 | Hamman John P. | Modifying undesirable tastes |
WO2004012659A2 (en) * | 2002-08-01 | 2004-02-12 | Nitromed, Inc. | Nitrosated proton pump inhibitors, compositions and methods of use |
JPWO2004052125A1 (ja) * | 2002-12-06 | 2006-04-06 | 協和醗酵工業株式会社 | アミノ酸を含有する飲料およびアミノ酸の苦味を低減する方法 |
FR2857262B1 (fr) * | 2003-07-08 | 2007-10-05 | Biocodex Lab | Utilisation de la citrulline dans le cadre de l'insuffisance intestinale |
WO2005107735A2 (en) * | 2004-04-30 | 2005-11-17 | Pump Formulations, Ltd. | Nutritional composition for enhancing lean muscle stimulus, growth, strength and recovery, creating and prolonging intense muscle pumps, supporting endurance, strength, performance, size and stamina, providing a transducer effect for nitric oxide, incresing nutrient delivery and/or promoting increased vascular response in a |
WO2006002096A2 (en) * | 2004-06-18 | 2006-01-05 | Vivo Therapeutics, Inc. | Low doses of l-citrulline for treating diseases |
US20060046982A1 (en) * | 2004-08-26 | 2006-03-02 | Waugh William H | Orthomolecular medical use of L-citrulline for capillary endothelial protection and adjacent cell protection in neurodegenerative disease |
-
2007
- 2007-04-02 BR BRPI0710044-2A patent/BRPI0710044A2/pt not_active IP Right Cessation
- 2007-04-02 EP EP13150724.6A patent/EP2612666A3/en not_active Withdrawn
- 2007-04-02 MX MX2008012723A patent/MX2008012723A/es not_active Application Discontinuation
- 2007-04-02 US US12/293,283 patent/US20090291877A1/en not_active Abandoned
- 2007-04-02 AU AU2007233371A patent/AU2007233371B2/en not_active Ceased
- 2007-04-02 CA CA2648126A patent/CA2648126C/en not_active Expired - Fee Related
- 2007-04-02 JP JP2009504245A patent/JP2009533342A/ja active Pending
- 2007-04-02 CA CA2778823A patent/CA2778823A1/en not_active Abandoned
- 2007-04-02 RU RU2008143310/14A patent/RU2444355C2/ru not_active IP Right Cessation
- 2007-04-02 EP EP13175960.7A patent/EP2679223A1/en not_active Withdrawn
- 2007-04-02 CN CN2012103324817A patent/CN102935231A/zh active Pending
- 2007-04-02 WO PCT/US2007/008143 patent/WO2007114903A2/en active Application Filing
- 2007-04-02 EP EP07754640A patent/EP2004171A2/en not_active Withdrawn
-
2008
- 2008-09-18 IL IL194202A patent/IL194202A0/en unknown
- 2008-11-03 ZA ZA2008/09393A patent/ZA200809393B/en unknown
-
2009
- 2009-05-26 HK HK09104767.4A patent/HK1126390A1/xx not_active IP Right Cessation
-
2012
- 2012-05-21 JP JP2012115906A patent/JP2012197283A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
MX2008012723A (es) | 2008-10-14 |
IL194202A0 (en) | 2009-09-22 |
AU2007233371A1 (en) | 2007-10-11 |
CA2648126C (en) | 2012-12-18 |
JP2009533342A (ja) | 2009-09-17 |
EP2612666A3 (en) | 2013-10-02 |
US20090291877A1 (en) | 2009-11-26 |
BRPI0710044A2 (pt) | 2011-08-02 |
EP2004171A2 (en) | 2008-12-24 |
WO2007114903A2 (en) | 2007-10-11 |
ZA200809393B (en) | 2009-12-30 |
EP2612666A2 (en) | 2013-07-10 |
CN102935231A (zh) | 2013-02-20 |
CA2648126A1 (en) | 2007-10-11 |
WO2007114903A3 (en) | 2008-02-14 |
RU2444355C2 (ru) | 2012-03-10 |
RU2008143310A (ru) | 2010-05-10 |
JP2012197283A (ja) | 2012-10-18 |
CA2778823A1 (en) | 2007-10-11 |
EP2679223A1 (en) | 2014-01-01 |
AU2007233371B2 (en) | 2012-11-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1126390A1 (en) | Use of citrulline in the manufacture of a medicament for the correction of arginine deficiency in septic patients | |
DE602006007093D1 (de) | Kombinationstherapie zur Behandlung von Diabetes und dadurch bedingten Leiden sowie zur Behandlung von mittels Erhöhung des GLP-1-Spiegels im Blut verbesserten Leiden | |
MX2008006076A (es) | Metodos, composiciones y kits para el tratamiento de condiciones medicas. | |
MY151018A (en) | Use of nutritional compositions for preventing disorders | |
HK1141237A1 (en) | Glp-1-fc fusion protein formulation glp-1-fc | |
WO2006119958A3 (en) | Use of flibanserin in the treatment of chronic pain | |
UA90048C2 (ru) | Кондиционированная композиция и способ ее получения | |
MY176679A (en) | Use of nutritional compositions for preventing disorders | |
ATE551063T1 (de) | Verwendung von bifidobacterium longum zur prophylaxe und behandlung von entzündungen | |
MY156243A (en) | Treatment for diabetes in patients inappropriate for metformin therapy | |
ATE456369T1 (de) | Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen | |
PL385586A1 (pl) | Nowe analogi insuliny o przedłużonym działaniu | |
DE602005024352D1 (de) | Implantate zur Flüssigkeitsbehandlung mit verbesserter Verschlussbeständigkeit | |
MY153408A (en) | Novel methods | |
BRPI0509210A (pt) | uso de gaboxadol, e, métodos para tratar função respiratória enfraquecida, e apnéia do sono | |
MX2013008729A (es) | Metodos y composiciones para tratar, reducir, o prevenir el deterioro del sistema visual de los animales. | |
WO2007130501A3 (en) | Combination therapy for treatment of cancer | |
AU2016204146A1 (en) | Methods of Increasing Neuronal Differentiation Using Antibodies to Lysophoshatidic Acid | |
SE0700456L (sv) | Injicerbar suspension innefattande titan-,titanlegerings- eller titanoxidpartiklar av mikrostruktur | |
ATE539764T1 (de) | Verwendung mutierter antithrombine zur behandlung oder verhinderung von gerinnungserkrankungen | |
WO2010101301A9 (en) | Prophylaxis and treatment of macular degeneration and retinopathy using a prdx protein | |
WO2012016229A3 (en) | Oxytocin treatment to improve memory and modify blood glucose | |
MX2010003615A (es) | Tratamiento de desordenes neurologicos. | |
EA200601853A1 (ru) | Лечение нарушенной дыхательной функции | |
MX2009003676A (es) | Compuestos s-nitrosotiol y derivados relacionados. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20170402 |