HK1122808A1 - Preparation and use of tetrahydropyrrolo [3, 2-c]t pyridin-4-one derivatives for treatment of obesitty, psychiatric and neurological disorders - Google Patents
Preparation and use of tetrahydropyrrolo [3, 2-c]t pyridin-4-one derivatives for treatment of obesitty, psychiatric and neurological disordersInfo
- Publication number
- HK1122808A1 HK1122808A1 HK08114099.3A HK08114099A HK1122808A1 HK 1122808 A1 HK1122808 A1 HK 1122808A1 HK 08114099 A HK08114099 A HK 08114099A HK 1122808 A1 HK1122808 A1 HK 1122808A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- obesitty
- tetrahydropyrrolo
- psychiatric
- pyridin
- derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
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- Hematology (AREA)
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- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
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- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72415605P | 2005-10-06 | 2005-10-06 | |
PCT/GB2006/003695 WO2007039740A2 (en) | 2005-10-06 | 2006-10-05 | Preparation and use of tetrahydropyrrolo [3, 2-c] pyridin-4-one derivatives for treatment of obesity, psychiatric and neurological disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1122808A1 true HK1122808A1 (en) | 2009-05-29 |
Family
ID=37781800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08114099.3A HK1122808A1 (en) | 2005-10-06 | 2008-12-30 | Preparation and use of tetrahydropyrrolo [3, 2-c]t pyridin-4-one derivatives for treatment of obesitty, psychiatric and neurological disorders |
Country Status (21)
Country | Link |
---|---|
US (2) | US7875626B2 (zh) |
EP (1) | EP1937679B1 (zh) |
JP (1) | JP4277062B2 (zh) |
KR (1) | KR20080058456A (zh) |
CN (1) | CN101277957A (zh) |
AR (1) | AR056560A1 (zh) |
AT (1) | ATE440099T1 (zh) |
AU (1) | AU2006298530B2 (zh) |
BR (1) | BRPI0616653A2 (zh) |
CA (1) | CA2624495A1 (zh) |
DE (1) | DE602006008641D1 (zh) |
EC (1) | ECSP088413A (zh) |
ES (1) | ES2329616T3 (zh) |
HK (1) | HK1122808A1 (zh) |
IL (1) | IL190025A0 (zh) |
NO (1) | NO20081523L (zh) |
RU (1) | RU2415856C2 (zh) |
TW (1) | TW200730525A (zh) |
UY (1) | UY29838A1 (zh) |
WO (1) | WO2007039740A2 (zh) |
ZA (1) | ZA200802946B (zh) |
Families Citing this family (27)
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AR056560A1 (es) * | 2005-10-06 | 2007-10-10 | Astrazeneca Ab | Pirrolopiridinonas como moduladores cb1 |
EP1973910B1 (en) * | 2006-01-27 | 2013-06-26 | Shanghai Hengrui Pharmaceutical Co. Ltd. | Pyrrolo[3,2-c]pyridine-4-one 2-indolinone protein kinase inhibitors |
EP2061767B1 (de) | 2006-08-08 | 2014-12-17 | Sanofi | Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung |
AR065909A1 (es) * | 2007-04-03 | 2009-07-08 | Astrazeneca Ab | Agentes terapeuticos 685 |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
JP4719317B2 (ja) * | 2008-02-26 | 2011-07-06 | 武田薬品工業株式会社 | 縮合複素環誘導体およびその用途 |
TW201014822A (en) | 2008-07-09 | 2010-04-16 | Sanofi Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
US20110015154A1 (en) * | 2009-07-20 | 2011-01-20 | Kellermann Gottfried H | Supporting acetylcholine function |
DK2470552T3 (en) | 2009-08-26 | 2014-02-17 | Sanofi Sa | NOVEL, CRYSTALLINE, heteroaromatic FLUORGLYCOSIDHYDRATER, MEDICINES COVERING THESE COMPOUNDS AND THEIR USE |
US20110098265A1 (en) * | 2009-10-28 | 2011-04-28 | Neuroscience, Inc. | Methods for reducing cravings and impulses associated with addictive and compulsive behaviors |
US8933024B2 (en) | 2010-06-18 | 2015-01-13 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
KR101273643B1 (ko) * | 2010-10-12 | 2013-06-11 | 한국화학연구원 | 5,6-디하이드로-피롤로[3,4-b]피리딘-7-온 유도체 또는 이의 약학적으로 허용 가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 약학적 조성물 |
WO2012120053A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8828994B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
US8901114B2 (en) | 2011-03-08 | 2014-12-02 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US9560630B2 (en) * | 2011-08-12 | 2017-01-31 | Qualcomm Incorporated | Devices for reduced overhead paging |
JP6471103B2 (ja) | 2013-03-06 | 2019-02-13 | ヤンセン ファーマシューティカ エヌ.ベー. | ヒスタミンh4受容体のベンゾイミダゾール−2−イルピリミジンモジュレータ |
UA122221C2 (uk) | 2015-01-28 | 2020-10-12 | Байєр Фарма Акцієнгезелльшафт | 4Н-ПІРОЛО[3,2-c]ПІРИДИН-4-ОНОВІ ПОХІДНІ |
WO2020074403A1 (en) * | 2018-10-08 | 2020-04-16 | Universität Zürich | Appetite-modulating molecules |
US20230046077A1 (en) | 2019-02-07 | 2023-02-16 | Bayer Aktiengesellschaft | 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as csnk1 inhibitors |
US20210015762A1 (en) * | 2019-07-16 | 2021-01-21 | TRUETIVA, Inc. | Compositions for treating obesity |
KR20210103688A (ko) | 2020-02-14 | 2021-08-24 | (주) 디엔테크 | 오링용 고무조성물 |
US20230365554A1 (en) | 2020-07-29 | 2023-11-16 | The Broad Institute, Inc. | Substituted pyrrolo-pyridinone derivatives and therapeutic uses thereof |
US20230322767A1 (en) | 2020-07-29 | 2023-10-12 | Bayer Aktiengesellschaft | Aryl substituted pyrrolo-pyridinones and therapeutic uses thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
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FR2692575B1 (fr) * | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
FR2714057B1 (fr) * | 1993-12-17 | 1996-03-08 | Sanofi Elf | Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant. |
FR2758723B1 (fr) * | 1997-01-28 | 1999-04-23 | Sanofi Sa | Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour la preparation de medicaments |
US6858616B2 (en) * | 1998-12-23 | 2005-02-22 | Bristol-Myers Squibb Pharma Company | Nitrogen containing heterobicycles as factor Xa inhibitors |
DZ3335A1 (fr) | 2000-03-23 | 2001-09-27 | Solvay Pharm Bv | Derives de 4,5-dihydro-1h-pyrazole ayant une activite antagoniste de cb1 |
JP2005504100A (ja) * | 2001-09-24 | 2005-02-10 | バイエル・フアーマシユーチカルズ・コーポレーシヨン | 肥満の治療のための1,5,6,7−テトラヒドロピロロ[3,2−c]ピリジン誘導体の製造法および使用 |
GB0403780D0 (en) | 2004-02-20 | 2004-03-24 | Astrazeneca Ab | Therapeutic agents |
EP1718617B1 (en) | 2004-02-20 | 2009-08-19 | AstraZeneca AB | 3-substituted 1,5-diphenylpyrazole derivatives useful as cb1 modulators |
RU2377238C2 (ru) | 2004-04-03 | 2009-12-27 | Астразенека Аб | Производные имидазола, активные в отношении рецептора св1 |
AR056560A1 (es) * | 2005-10-06 | 2007-10-10 | Astrazeneca Ab | Pirrolopiridinonas como moduladores cb1 |
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2006
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- 2006-10-05 AU AU2006298530A patent/AU2006298530B2/en not_active Ceased
- 2006-10-05 ES ES06794647T patent/ES2329616T3/es active Active
- 2006-10-05 BR BRPI0616653-9A patent/BRPI0616653A2/pt not_active IP Right Cessation
- 2006-10-05 RU RU2008109185/04A patent/RU2415856C2/ru not_active IP Right Cessation
- 2006-10-05 CN CNA2006800365273A patent/CN101277957A/zh active Pending
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- 2006-10-05 KR KR1020087010582A patent/KR20080058456A/ko not_active Application Discontinuation
- 2006-10-05 DE DE602006008641T patent/DE602006008641D1/de active Active
- 2006-10-05 EP EP06794647A patent/EP1937679B1/en active Active
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Also Published As
Publication number | Publication date |
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JP4277062B2 (ja) | 2009-06-10 |
AU2006298530A1 (en) | 2007-04-12 |
ECSP088413A (es) | 2008-05-30 |
WO2007039740A2 (en) | 2007-04-12 |
CA2624495A1 (en) | 2007-04-12 |
CN101277957A (zh) | 2008-10-01 |
JP2009504722A (ja) | 2009-02-05 |
KR20080058456A (ko) | 2008-06-25 |
US7875626B2 (en) | 2011-01-25 |
NO20081523L (no) | 2008-07-02 |
TW200730525A (en) | 2007-08-16 |
UY29838A1 (es) | 2007-05-31 |
IL190025A0 (en) | 2008-08-07 |
US20080312269A1 (en) | 2008-12-18 |
AU2006298530B2 (en) | 2009-10-29 |
BRPI0616653A2 (pt) | 2011-06-28 |
WO2007039740A3 (en) | 2007-05-31 |
US7576095B2 (en) | 2009-08-18 |
RU2415856C2 (ru) | 2011-04-10 |
RU2008109185A (ru) | 2009-11-20 |
US20080009513A1 (en) | 2008-01-10 |
AR056560A1 (es) | 2007-10-10 |
DE602006008641D1 (de) | 2009-10-01 |
ATE440099T1 (de) | 2009-09-15 |
EP1937679A2 (en) | 2008-07-02 |
ES2329616T3 (es) | 2009-11-27 |
ZA200802946B (en) | 2009-03-25 |
EP1937679B1 (en) | 2009-08-19 |
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