HK1106513A1 - Novel azabicyclic aryl derivatives and their medical use - Google Patents

Novel azabicyclic aryl derivatives and their medical use

Info

Publication number
HK1106513A1
HK1106513A1 HK07111831.3A HK07111831A HK1106513A1 HK 1106513 A1 HK1106513 A1 HK 1106513A1 HK 07111831 A HK07111831 A HK 07111831A HK 1106513 A1 HK1106513 A1 HK 1106513A1
Authority
HK
Hong Kong
Prior art keywords
diseases
disorders
compounds
pyridazinyl
medical use
Prior art date
Application number
HK07111831.3A
Other languages
English (en)
Inventor
Dan Peters
Daniel B Timmermann
Gunnar M Olsen
Elsebet Ostergaard Nielsen
Tino Dyhring Jorgensen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of HK1106513A1 publication Critical patent/HK1106513A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
HK07111831.3A 2004-10-15 2007-11-01 Novel azabicyclic aryl derivatives and their medical use HK1106513A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200401582 2004-10-15
PCT/EP2005/055263 WO2006040352A1 (en) 2004-10-15 2005-10-14 Novel azabicyclic aryl derivatives and their medical use

Publications (1)

Publication Number Publication Date
HK1106513A1 true HK1106513A1 (en) 2008-03-14

Family

ID=38744785

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07111831.3A HK1106513A1 (en) 2004-10-15 2007-11-01 Novel azabicyclic aryl derivatives and their medical use

Country Status (9)

Country Link
US (1) US7652010B2 (xx)
EP (1) EP1802616B1 (xx)
CN (1) CN100588657C (xx)
AT (1) ATE495172T1 (xx)
AU (1) AU2005293510A1 (xx)
CA (1) CA2584836A1 (xx)
DE (1) DE602005025902D1 (xx)
HK (1) HK1106513A1 (xx)
WO (1) WO2006040352A1 (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
PE20060437A1 (es) 2004-06-18 2006-06-08 Novartis Ag COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
US7855208B2 (en) 2006-02-14 2010-12-21 Neurosearch A/S 3, 9-diazabicyclo(3.3.1)non-3-yl-aryl methanone derivatives as nicotinic acetylcholine receptor agonists
EP1987029B1 (en) * 2006-02-16 2010-01-13 Neurosearch A/S Enantiopure quinuclidinyloxy pyridazines and their use as nicotinic acetylcholine receptor ligands
US8314119B2 (en) 2006-11-06 2012-11-20 Abbvie Inc. Azaadamantane derivatives and methods of use
JO3250B1 (ar) 2009-09-22 2018-09-16 Novartis Ag إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7
CN106074548A (zh) 2010-09-23 2016-11-09 艾伯维巴哈马有限公司 氮杂金刚烷衍生物的一水合物
JP6612874B2 (ja) 2014-12-16 2019-11-27 アクソファント サイエンシーズ ゲーエムベーハー α７−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換キヌクリジンアミド化合物
US10370370B2 (en) 2015-06-10 2019-08-06 Axovant Sciences Gmbh Aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors
US10428062B2 (en) 2015-08-12 2019-10-01 Axovant Sciences Gmbh Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors
CN109593088B (zh) * 2018-12-27 2022-03-25 华东理工大学 氮杂双环衍生物及其制备和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2791678B1 (fr) 1999-03-30 2001-05-04 Synthelabo Derives de 1,4-diazabicyclo [3.2.2] nonane-4-carboxylates et -carboxamides, leur preparation et leur application en therapeutique
US6492385B2 (en) * 2000-08-18 2002-12-10 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
CA2488761C (en) 2002-06-10 2011-05-31 Bayer Healthcare Ag 2-benzofuryl or benzothiophenyl-quinuclidinyl amides as nicotinic acetylcholine receptor inhibitors
SE0202430D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab New Compounds
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
EP1802616A1 (en) 2007-07-04
CN100588657C (zh) 2010-02-10
WO2006040352A1 (en) 2006-04-20
CN101027300A (zh) 2007-08-29
US20070299082A1 (en) 2007-12-27
ATE495172T1 (de) 2011-01-15
CA2584836A1 (en) 2006-04-20
US7652010B2 (en) 2010-01-26
EP1802616B1 (en) 2011-01-12
AU2005293510A1 (en) 2006-04-20
DE602005025902D1 (de) 2011-02-24

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20131014