DE602005025902D1 - Neue azabizyklische arylderivate und medizinische verwendung damit - Google Patents

Neue azabizyklische arylderivate und medizinische verwendung damit

Info

Publication number
DE602005025902D1
DE602005025902D1 DE602005025902T DE602005025902T DE602005025902D1 DE 602005025902 D1 DE602005025902 D1 DE 602005025902D1 DE 602005025902 T DE602005025902 T DE 602005025902T DE 602005025902 T DE602005025902 T DE 602005025902T DE 602005025902 D1 DE602005025902 D1 DE 602005025902D1
Authority
DE
Germany
Prior art keywords
diseases
disorders
compounds
azabic
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005025902T
Other languages
English (en)
Inventor
Dan Peters
Daniel B Timmermann
Gunnar M Olsen
Elsebet Oestergaard Nielsen
Tino Dyhring Joergensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTG Nordic Transport Group AS
Original Assignee
Neurosearch AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch AS filed Critical Neurosearch AS
Publication of DE602005025902D1 publication Critical patent/DE602005025902D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE602005025902T 2004-10-15 2005-10-14 Neue azabizyklische arylderivate und medizinische verwendung damit Active DE602005025902D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61859804P 2004-10-15 2004-10-15
DKPA200401582 2004-10-15
PCT/EP2005/055263 WO2006040352A1 (en) 2004-10-15 2005-10-14 Novel azabicyclic aryl derivatives and their medical use

Publications (1)

Publication Number Publication Date
DE602005025902D1 true DE602005025902D1 (de) 2011-02-24

Family

ID=38744785

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005025902T Active DE602005025902D1 (de) 2004-10-15 2005-10-14 Neue azabizyklische arylderivate und medizinische verwendung damit

Country Status (9)

Country Link
US (1) US7652010B2 (de)
EP (1) EP1802616B1 (de)
CN (1) CN100588657C (de)
AT (1) ATE495172T1 (de)
AU (1) AU2005293510A1 (de)
CA (1) CA2584836A1 (de)
DE (1) DE602005025902D1 (de)
HK (1) HK1106513A1 (de)
WO (1) WO2006040352A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
PE20060437A1 (es) 2004-06-18 2006-06-08 Novartis Ag COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
EP1987032A1 (de) 2006-02-14 2008-11-05 NeuroSearch A/S 3, 9-diazabicyclo(3.3.1)non-3-yl-arylmethanon-derivate als nikotin-acetylcholin-rezeptoragonisten
DE602007004307D1 (de) * 2006-02-16 2010-03-04 Neurosearch As Enantiomerenreine chinuclidinyloxy-pyridazine und ihre verwendung als nikotin-acetylcholin-rezeptorliganden
US8314119B2 (en) * 2006-11-06 2012-11-20 Abbvie Inc. Azaadamantane derivatives and methods of use
JO3250B1 (ar) 2009-09-22 2018-09-16 Novartis Ag إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7
AU2011305462B2 (en) 2010-09-23 2015-11-26 Abbvie Bahamas Ltd. Monohydrate of an azaadamantane derivative
WO2016100184A1 (en) 2014-12-16 2016-06-23 Forum Pharmaceuticals, Inc. Geminal substituted quinuclidine amide compounds as agonists of alpha-7 nicotinic acetylcholine receptors
JP2018516973A (ja) 2015-06-10 2018-06-28 フォーラム・ファーマシューティカルズ・インコーポレイテッドForum Pharmaceuticals Inc. α7−ニコチン性アセチルコリン受容体のアゴニストとしてのアミノベンゾイソオキサゾール化合物
US10428062B2 (en) 2015-08-12 2019-10-01 Axovant Sciences Gmbh Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors
CN109593088B (zh) * 2018-12-27 2022-03-25 华东理工大学 氮杂双环衍生物及其制备和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2791678B1 (fr) * 1999-03-30 2001-05-04 Synthelabo Derives de 1,4-diazabicyclo [3.2.2] nonane-4-carboxylates et -carboxamides, leur preparation et leur application en therapeutique
US6492385B2 (en) * 2000-08-18 2002-12-10 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
MXPA04012439A (es) * 2002-06-10 2005-04-19 Bayer Healthcare Ag Amidas de acidos 2-heteroarilcarboxilicos.
SE0202430D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab New Compounds
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
US20070299082A1 (en) 2007-12-27
US7652010B2 (en) 2010-01-26
CN101027300A (zh) 2007-08-29
CN100588657C (zh) 2010-02-10
WO2006040352A1 (en) 2006-04-20
CA2584836A1 (en) 2006-04-20
HK1106513A1 (en) 2008-03-14
ATE495172T1 (de) 2011-01-15
EP1802616A1 (de) 2007-07-04
EP1802616B1 (de) 2011-01-12
AU2005293510A1 (en) 2006-04-20

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