HK1104965A1 - Granules comprising a non-steroidal anti-inflammatory drug and a sugar alcohol made by melt extrusion - Google Patents

Granules comprising a non-steroidal anti-inflammatory drug and a sugar alcohol made by melt extrusion

Info

Publication number
HK1104965A1
HK1104965A1 HK07110249.1A HK07110249A HK1104965A1 HK 1104965 A1 HK1104965 A1 HK 1104965A1 HK 07110249 A HK07110249 A HK 07110249A HK 1104965 A1 HK1104965 A1 HK 1104965A1
Authority
HK
Hong Kong
Prior art keywords
granules
sugar alcohol
steroidal anti
melt extrusion
inflammatory drug
Prior art date
Application number
HK07110249.1A
Other languages
English (en)
Inventor
Robert Sherry
Original Assignee
Reckitt Benckiser Healthcare
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0417942A external-priority patent/GB0417942D0/en
Priority claimed from GB0417939A external-priority patent/GB0417939D0/en
Application filed by Reckitt Benckiser Healthcare filed Critical Reckitt Benckiser Healthcare
Publication of HK1104965A1 publication Critical patent/HK1104965A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK07110249.1A 2004-08-12 2007-09-20 Granules comprising a non-steroidal anti-inflammatory drug and a sugar alcohol made by melt extrusion HK1104965A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0417942A GB0417942D0 (en) 2004-08-12 2004-08-12 Therapeutic agents
GB0417939A GB0417939D0 (en) 2004-08-12 2004-08-12 Therapeutic agents
PCT/GB2005/003077 WO2006016125A1 (fr) 2004-08-12 2005-08-08 Granules composes de « a ains » et d’un polyol fabrique par extrusion de matiere fondue

Publications (1)

Publication Number Publication Date
HK1104965A1 true HK1104965A1 (en) 2008-02-01

Family

ID=35044771

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07110249.1A HK1104965A1 (en) 2004-08-12 2007-09-20 Granules comprising a non-steroidal anti-inflammatory drug and a sugar alcohol made by melt extrusion

Country Status (15)

Country Link
US (2) US20080085308A1 (fr)
EP (2) EP1804772B1 (fr)
JP (2) JP2008509206A (fr)
KR (3) KR101232114B1 (fr)
CN (2) CN102631325A (fr)
AR (2) AR052523A1 (fr)
AT (1) ATE526949T1 (fr)
AU (3) AU2005271036B2 (fr)
CA (2) CA2576642A1 (fr)
HK (1) HK1104965A1 (fr)
MX (2) MX2007001689A (fr)
PL (2) PL1799195T3 (fr)
PT (1) PT1804772E (fr)
RU (2) RU2389478C2 (fr)
WO (2) WO2006016126A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0519350D0 (en) * 2005-09-22 2005-11-02 Boots Healthcare Int Ltd Therapeutic agents
CN101340896A (zh) * 2005-12-22 2009-01-07 特瓦制药工业有限公司 含有低溶解性药物的压缩的固体剂型和其制备方法
EP1808163A1 (fr) * 2005-12-22 2007-07-18 Teva Pharmaceutical Industries Ltd. Formes galéniques solides comprimées avec des principes actifs de faible solubilité et leur procédé de fabrication
US8083603B2 (en) * 2007-11-09 2011-12-27 Qubicaamf Worldwide Llc Bowling bumper system and method of use and installation
JPWO2009128543A1 (ja) * 2008-04-17 2011-08-04 ニプロ株式会社 シリカを含む錠剤の製造方法、錠剤及び錠剤用複合粒子
US8759279B2 (en) * 2008-06-30 2014-06-24 Kimberly-Clark Worldwide, Inc. Fragranced biodegradable film
EP2323976A4 (fr) * 2008-08-14 2014-07-02 Shasun Chemicals And Drugs Ltd Sels d acide arylalkylcarboxylique, procédé pour leur préparation et formes galéniques
EP2238974B9 (fr) * 2009-04-09 2014-05-21 E-Pharma Trento S.p.A. Granulé pour la formulation de comprimés orodispersibles
RU2715680C2 (ru) * 2009-06-22 2020-03-03 ВАЙЕТ ЭлЭлСи Таблетки ибупрофена натрия и способы изготовления фармацевтических композиций, включающих ибупрофен натрия
EA019805B1 (ru) * 2010-09-16 2014-06-30 Закрытое Акционерное Общество "Афофарм" Комбинированный анальгетик на основе парацетамола
JP5750856B2 (ja) * 2010-10-04 2015-07-22 ライオン株式会社 固形医薬組成物及び医薬製剤
RU2449777C1 (ru) * 2010-12-20 2012-05-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Новосибирский национальный исследовательский государственный университет" (Новосибирский государственный университет, НГУ) Способ получения высокодисперсного парацетамола
JP6255908B2 (ja) * 2012-11-09 2018-01-10 大正製薬株式会社 固形製剤
FR2997856B1 (fr) * 2012-11-14 2015-04-24 Pf Medicament Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
CN104968335A (zh) 2013-01-07 2015-10-07 三亚制药(株) 具有改善的溶解度的新型快速溶解颗粒制剂
CN104723597B (zh) * 2015-03-23 2017-04-05 辽宁天亿机械有限公司 一种间歇式压片机
WO2018197932A1 (fr) * 2017-04-27 2018-11-01 Dr. Reddy's Laboratories Ltd. Compositions pharmaceutiques de kétorolac
WO2023281089A2 (fr) 2021-07-08 2023-01-12 Krka, D.D., Novo Mesto Composition pharmaceutique comprenant du naproxène et du paracétamol
CN114041519A (zh) * 2021-11-25 2022-02-15 浙江华康药业股份有限公司 一种制备可直接压片木糖醇颗粒的方法
AU2022201576A1 (en) * 2022-03-08 2023-09-28 Aft Pharmaceuticals Limited Medication
WO2024097694A1 (fr) * 2022-11-04 2024-05-10 Johnson & Johnson Consumer Inc. Acétaminophène et naproxène pour le traitement de la douleur

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH677606A5 (fr) * 1988-07-12 1991-06-14 Aesculapius Pharma Sa
US5075291A (en) * 1989-11-22 1991-12-24 Ici Americas Inc. Crystalline sugar alcohol containing uniformly dispersed particulate pharmaceutical compound
HU219242B (en) * 1991-05-13 2001-03-28 Boots Co Plc S(+)-ibuprofen sodium salt dihydrate, pharmaceutical composition comprising this compound and process for production of them
WO1993004675A1 (fr) * 1991-09-06 1993-03-18 Mcneilab, Inc. Composition renfermant une matiere a base de tramadol et de l'acetaminophene, et son utilisation
US5409709A (en) * 1991-11-29 1995-04-25 Lion Corporation Antipyretic analgesic preparation containing ibuprofen
FR2705677B1 (fr) * 1993-05-28 1995-08-11 Roquette Freres Micro-granules obtenus par extrusion-sphéronisation contenant une cyclodextrine.
DE19504832A1 (de) * 1995-02-14 1996-08-22 Basf Ag Feste Wirkstoff-Zubereitungen
GB9603699D0 (en) * 1996-02-21 1996-04-17 Boots Co Plc Therapeutic composition
GB9616536D0 (en) * 1996-08-06 1996-09-25 Quadrant Holdings Cambridge Co-amoxiclav dosage form
US6649186B1 (en) * 1996-09-20 2003-11-18 Ethypharm Effervescent granules and methods for their preparation
US6160020A (en) * 1996-12-20 2000-12-12 Mcneill-Ppc, Inc. Alkali metal and alkaline-earth metal salts of acetaminophen
DE19710213A1 (de) * 1997-03-12 1998-09-17 Basf Ag Verfahren zur Herstellung von festen Kombinationsarzneiformen
DE19809242A1 (de) * 1998-03-05 1999-09-09 Basf Ag Verfahren zur Herstellung von festen, sphärischen Formkörpern, enthaltend pharmazeutische Wirkstoffe in einer Bindemittelmatrix
EP1301186A1 (fr) * 2000-07-19 2003-04-16 Lavipharm Laboratories, Inc. Dispersions solides de citrate de sildenafil ayant une forte solubilite dans l'eau
FR2814366A1 (fr) * 2000-09-22 2002-03-29 Rhodia Chimie Sa Procede de granulation de matieres actives par extrusion basse pression pour l'obtention de granules directement compressibles
AU2002255190A1 (en) * 2001-04-10 2002-10-28 Fakhreddin Jamali Composition for enhanced absorption of nsaids
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
GB0113843D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
GB0113842D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
US6766817B2 (en) * 2001-07-25 2004-07-27 Tubarc Technologies, Llc Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action
CH693586A8 (de) * 2002-10-14 2003-12-15 Roche Consumer Health Ag Darreichungsform von Ibuprofen-Natrium.

Also Published As

Publication number Publication date
RU2389480C2 (ru) 2010-05-20
AU2010200633A1 (en) 2010-03-11
AR050783A1 (es) 2006-11-22
AU2010200633B2 (en) 2013-01-31
WO2006016125A1 (fr) 2006-02-16
MX2007001689A (es) 2007-06-11
CN102784113A (zh) 2012-11-21
PT1804772E (pt) 2011-12-02
JP2008509206A (ja) 2008-03-27
CA2576652A1 (fr) 2006-02-16
KR20070062978A (ko) 2007-06-18
WO2006016126A1 (fr) 2006-02-16
CN102631325A (zh) 2012-08-15
KR101482922B1 (ko) 2015-01-15
RU2389478C2 (ru) 2010-05-20
AR052523A1 (es) 2007-03-21
EP1799195A1 (fr) 2007-06-27
KR20070069143A (ko) 2007-07-02
KR101232114B1 (ko) 2013-02-13
MX2007001597A (es) 2007-05-23
AU2005271036A1 (en) 2006-02-16
ATE526949T1 (de) 2011-10-15
US20080085308A1 (en) 2008-04-10
AU2005271035B2 (en) 2009-09-17
KR20130014647A (ko) 2013-02-07
EP1799195B1 (fr) 2016-03-23
RU2007108778A (ru) 2008-09-20
US20070254028A1 (en) 2007-11-01
PL1804772T3 (pl) 2012-03-30
AU2005271036B2 (en) 2009-11-19
RU2007108779A (ru) 2008-09-20
AU2005271035A1 (en) 2006-02-16
JP2008509207A (ja) 2008-03-27
EP1804772B1 (fr) 2011-10-05
CA2576642A1 (fr) 2006-02-16
EP1804772A1 (fr) 2007-07-11
PL1799195T3 (pl) 2016-09-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150808