HK1102197A1 - Hif prolyl hydroxylase activity assay - Google Patents

Hif prolyl hydroxylase activity assay

Info

Publication number
HK1102197A1
HK1102197A1 HK07110215.1A HK07110215A HK1102197A1 HK 1102197 A1 HK1102197 A1 HK 1102197A1 HK 07110215 A HK07110215 A HK 07110215A HK 1102197 A1 HK1102197 A1 HK 1102197A1
Authority
HK
Hong Kong
Prior art keywords
activity assay
prolyl hydroxylase
hydroxylase activity
hif prolyl
methods
Prior art date
Application number
HK07110215.1A
Other languages
English (en)
Inventor
Mitchell C Brenner
Original Assignee
Fibrogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrogen Inc filed Critical Fibrogen Inc
Publication of HK1102197A1 publication Critical patent/HK1102197A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90245—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
HK07110215.1A 2004-05-28 2007-09-20 Hif prolyl hydroxylase activity assay HK1102197A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57532404P 2004-05-28 2004-05-28
PCT/US2005/018577 WO2005118836A2 (fr) 2004-05-28 2005-05-26 Essai d'activite de prolyl hydroxylase de hif

Publications (1)

Publication Number Publication Date
HK1102197A1 true HK1102197A1 (en) 2007-11-09

Family

ID=34979114

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07110215.1A HK1102197A1 (en) 2004-05-28 2007-09-20 Hif prolyl hydroxylase activity assay

Country Status (13)

Country Link
US (1) US20080113383A1 (fr)
EP (1) EP1766047B1 (fr)
JP (1) JP2008500834A (fr)
AT (1) ATE443775T1 (fr)
AU (1) AU2005250412B2 (fr)
CA (1) CA2567619A1 (fr)
DE (1) DE602005016800D1 (fr)
ES (1) ES2332798T3 (fr)
HK (1) HK1102197A1 (fr)
IL (1) IL179441A (fr)
NZ (1) NZ551632A (fr)
WO (1) WO2005118836A2 (fr)
ZA (1) ZA200610164B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101374815B (zh) 2006-01-27 2013-07-17 菲布罗根有限公司 使低氧诱导因子（hif）稳定的氰基异喹啉化合物
US7588924B2 (en) 2006-03-07 2009-09-15 Procter & Gamble Company Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
BRPI0710527B8 (pt) 2006-04-04 2021-05-25 Fibrogen Inc compostos de pirrolo- e tiazolo-piridina e composição farmacêutica que os compreende
HUE041300T2 (hu) 2006-06-26 2019-05-28 Akebia Therapeutics Inc Prolilhidroxiláz inhibitorok és alkalmazási eljárások
WO2011057112A1 (fr) 2009-11-06 2011-05-12 Akebia Therapeutics Inc. Procédés pour augmenter la stabilisation du facteur inductible par l'hypoxie 1-alpha
US8921389B2 (en) 2011-02-02 2014-12-30 Fibrogen, Inc. Naphthyridine derivatives as inhibitors of hypoxia inducible factor (HIF) hydroxylase
GB201102659D0 (en) 2011-02-15 2011-03-30 Isis Innovation Assay
US8865748B2 (en) 2011-06-06 2014-10-21 Akebia Therapeutics Inc. Compounds and compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer
NO2686520T3 (fr) 2011-06-06 2018-03-17
GB201113101D0 (en) 2011-07-28 2011-09-14 Isis Innovation Assay
AU2013229922B2 (en) 2012-03-09 2017-09-28 Fibrogen, Inc. 4 -hydroxy- isoquinoline compounds as HIF hydroxylase inhibitors
US9340511B2 (en) 2012-07-16 2016-05-17 Fibrogen, Inc. Process for making isoquinoline compounds
LT2872488T (lt) 2012-07-16 2018-10-25 Fibrogen, Inc. Kristalinės prolilhidroksilazės inhibitoriaus formos
NZ714963A (en) 2013-06-13 2020-07-31 Akebia Therapeutics Inc Compositions and methods for treating anemia
AU2016209126A1 (en) 2015-01-23 2017-08-10 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
NZ773901A (en) 2015-04-01 2024-07-26 Akebia Therapeutics Inc Compositions and methods for treating anemia
AU2019265629B2 (en) 2018-05-09 2024-09-12 Akebia Therapeutics, Inc. Process for preparing 2-((5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl)amino)acetic acid
CN114577945B (zh) * 2022-03-10 2023-06-02 中国科学院兰州化学物理研究所 一种从中药提取物中筛选脯氨酰羟化酶2抑制剂的胶束电动色谱方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002074981A2 (fr) * 2001-03-21 2002-09-26 Isis Innovation Ltd. Dosages, procedes et dispositifs
CN1602360A (zh) * 2001-12-06 2005-03-30 法布罗根股份有限公司 提高内源性红细胞生成素(epo)的方法

Also Published As

Publication number Publication date
US20080113383A1 (en) 2008-05-15
NZ551632A (en) 2009-09-25
JP2008500834A (ja) 2008-01-17
ES2332798T3 (es) 2010-02-12
WO2005118836A3 (fr) 2006-04-06
CA2567619A1 (fr) 2005-12-15
EP1766047A2 (fr) 2007-03-28
AU2005250412A1 (en) 2005-12-15
IL179441A (en) 2010-12-30
ATE443775T1 (de) 2009-10-15
EP1766047B1 (fr) 2009-09-23
IL179441A0 (en) 2007-05-15
ZA200610164B (en) 2008-02-27
DE602005016800D1 (de) 2009-11-05
AU2005250412B2 (en) 2009-09-17
WO2005118836A2 (fr) 2005-12-15

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130526