HK1098131A1 - Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer - Google Patents

Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer

Info

Publication number
HK1098131A1
HK1098131A1 HK07101845A HK07101845A HK1098131A1 HK 1098131 A1 HK1098131 A1 HK 1098131A1 HK 07101845 A HK07101845 A HK 07101845A HK 07101845 A HK07101845 A HK 07101845A HK 1098131 A1 HK1098131 A1 HK 1098131A1
Authority
HK
Hong Kong
Prior art keywords
cancer
treatment
production
bengamide derivatives
bengamide
Prior art date
Application number
HK07101845A
Other languages
English (en)
Inventor
Holger Hoffmann
Sabine Haag-Richter
Michael Kurz
Heiko Tietgen
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of HK1098131A1 publication Critical patent/HK1098131A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08Oxygen atoms
    • C07D223/10Oxygen atoms attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
HK07101845A 2003-10-24 2007-02-15 Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer HK1098131A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10349669A DE10349669B3 (de) 2003-10-24 2003-10-24 Bengamide-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
PCT/EP2004/011244 WO2005044803A1 (fr) 2003-10-24 2004-10-08 Derives de bengamide, procede de preparation desdits derives et leur utilisation pour traiter les maladies cancereuses

Publications (1)

Publication Number Publication Date
HK1098131A1 true HK1098131A1 (en) 2007-07-13

Family

ID=34484998

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07101845A HK1098131A1 (en) 2003-10-24 2007-02-15 Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer

Country Status (30)

Country Link
EP (2) EP1873146B1 (fr)
JP (1) JP4769190B2 (fr)
KR (1) KR20060120044A (fr)
CN (2) CN101294173A (fr)
AR (1) AR046553A1 (fr)
AT (2) ATE420074T1 (fr)
AU (1) AU2004287561B2 (fr)
BR (1) BRPI0415529A (fr)
CA (1) CA2543003A1 (fr)
CL (1) CL2009000674A1 (fr)
CY (1) CY1110458T1 (fr)
DE (3) DE10349669B3 (fr)
DK (1) DK1680405T3 (fr)
ES (1) ES2320894T3 (fr)
HK (1) HK1098131A1 (fr)
HR (1) HRP20090187T1 (fr)
IL (1) IL174524A (fr)
MA (1) MA28213A1 (fr)
ME (1) MEP33108A (fr)
MX (1) MXPA06004084A (fr)
NO (1) NO20062149L (fr)
NZ (1) NZ546744A (fr)
PL (1) PL1680405T3 (fr)
PT (1) PT1680405E (fr)
RS (1) RS20060263A (fr)
RU (1) RU2357956C2 (fr)
SI (1) SI1680405T1 (fr)
UY (1) UY28574A1 (fr)
WO (1) WO2005044803A1 (fr)
ZA (1) ZA200602231B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2878525B1 (fr) 2004-11-29 2007-02-23 Aventis Pharma Sa Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation
FR2878528B1 (fr) 2004-11-29 2008-05-16 Aventis Pharma Sa 2-alcoxy-3,4,5-trihydroxy-alkylamides, leur preparation, compositions les contenant et utilisation
FR2901556A1 (fr) 2006-05-24 2007-11-30 Sanofi Aventis Sa Derives de 2-alcoxy-3,4,5-trihydroxy-alkylamide, leur preparation, compositions les contenant et utilisation
FR2901554B1 (fr) 2006-05-24 2011-04-01 Sanofi Aventis 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzazepine, leur preparation, compositions les contenant et utilisation
FR2901555A1 (fr) 2006-05-24 2007-11-30 Sanofi Aventis Sa 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzothiazepine, leur preparation, compositions les contenant et utilisation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5140099A1 (es) * 1998-11-17 2002-03-22 Novartis Ag Ciertas caprolactamas sustituidas, composiciones farmaceuticas que las contienen, y su uso en el tratamiento de tumores
AU2001295206A1 (en) * 2000-05-11 2001-11-20 Novartis Ag Substituted caprolactam carbonates and ethers and their use as anti-tumor agents
JP2004262793A (ja) * 2003-02-28 2004-09-24 Noyaku Bio Technology Kaihatsu Gijutsu Kenkyu Kumiai 化合物n−9011、その製造法及び用途
BRPI0412843A (pt) * 2003-07-25 2006-09-26 Novartis Ag lactamas substituìdas e uso das mesmas como agentes anticáncer

Also Published As

Publication number Publication date
DE502004011536D1 (de) 2010-09-23
MXPA06004084A (es) 2006-06-27
KR20060120044A (ko) 2006-11-24
EP1680405A1 (fr) 2006-07-19
SI1680405T1 (sl) 2009-06-30
CN101294173A (zh) 2008-10-29
IL174524A (en) 2012-08-30
CL2009000674A1 (es) 2009-08-07
HRP20090187T1 (en) 2009-05-31
CN100398520C (zh) 2008-07-02
DK1680405T3 (da) 2009-05-04
EP1873146A2 (fr) 2008-01-02
DE10349669B3 (de) 2005-05-25
RU2006117769A (ru) 2007-11-27
AU2004287561A1 (en) 2005-05-19
PT1680405E (pt) 2009-03-31
IL174524A0 (en) 2006-08-01
CA2543003A1 (fr) 2005-05-19
ATE420074T1 (de) 2009-01-15
MA28213A1 (fr) 2006-10-02
JP4769190B2 (ja) 2011-09-07
AU2004287561B2 (en) 2011-06-02
ES2320894T3 (es) 2009-05-29
DE502004008837D1 (de) 2009-02-26
ATE477244T1 (de) 2010-08-15
JP2007509084A (ja) 2007-04-12
PL1680405T3 (pl) 2009-06-30
UY28574A1 (es) 2005-05-31
RS20060263A (en) 2008-09-29
NO20062149L (no) 2006-07-11
ZA200602231B (en) 2007-06-27
CN1871217A (zh) 2006-11-29
NZ546744A (en) 2009-03-31
EP1873146A3 (fr) 2008-05-21
CY1110458T1 (el) 2015-04-29
BRPI0415529A (pt) 2006-12-26
WO2005044803A1 (fr) 2005-05-19
RU2357956C2 (ru) 2009-06-10
EP1680405B1 (fr) 2009-01-07
EP1873146B1 (fr) 2010-08-11
AR046553A1 (es) 2005-12-14
MEP33108A (en) 2010-10-10

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20121008