HK1092711A1 - Pharmeceutical composition with improved solubility and fluidity - Google Patents

Pharmeceutical composition with improved solubility and fluidity

Info

Publication number
HK1092711A1
HK1092711A1 HK06113473A HK06113473A HK1092711A1 HK 1092711 A1 HK1092711 A1 HK 1092711A1 HK 06113473 A HK06113473 A HK 06113473A HK 06113473 A HK06113473 A HK 06113473A HK 1092711 A1 HK1092711 A1 HK 1092711A1
Authority
HK
Hong Kong
Prior art keywords
fluidity
improved solubility
pharmeceutical
composition
pharmeceutical composition
Prior art date
Application number
HK06113473A
Other languages
English (en)
Inventor
Hideyoshi Kanbe
Toshiaki Kurazumi
Teiji Murata
Original Assignee
Ssp Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ssp Co Ltd filed Critical Ssp Co Ltd
Publication of HK1092711A1 publication Critical patent/HK1092711A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK06113473A 2003-09-05 2006-12-07 Pharmeceutical composition with improved solubility and fluidity HK1092711A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003313853A JP4575654B2 (ja) 2003-09-05 2003-09-05 溶解性と流動性を改善した医薬組成物
PCT/JP2004/012827 WO2005023222A1 (ja) 2003-09-05 2004-09-03 溶解性と流動性を改善した医薬組成物

Publications (1)

Publication Number Publication Date
HK1092711A1 true HK1092711A1 (en) 2007-02-16

Family

ID=34269778

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06113473A HK1092711A1 (en) 2003-09-05 2006-12-07 Pharmeceutical composition with improved solubility and fluidity

Country Status (6)

Country Link
JP (1) JP4575654B2 (ko)
KR (1) KR20060119860A (ko)
CN (1) CN100389750C (ko)
HK (1) HK1092711A1 (ko)
TW (1) TWI344376B (ko)
WO (1) WO2005023222A1 (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5148296B2 (ja) * 2005-06-27 2013-02-20 第一三共株式会社 アンジオテンシンｉｉ受容体拮抗剤及びカルシウム拮抗剤含有医薬組成物
JP5670053B2 (ja) * 2006-11-13 2015-02-18 エシコン・インコーポレイテッドＥｔｈｉｃｏｎ， Ｉｎｃｏｒｐｏｒａｔｅｄ マイクロキャリアを使用した、産褥由来の細胞の生体外での拡大
JP5201819B2 (ja) * 2006-11-22 2013-06-05 エスエス製薬株式会社 固形組成物
JP5817715B2 (ja) * 2010-03-03 2015-11-18 ライオン株式会社 固形医薬組成物、医薬製剤及び固形医薬組成物の製造方法
CN105343006B (zh) * 2015-12-02 2019-05-14 北京大学 一种载难溶性药物的纳米骨架系统及其制备方法和应用
CN105832680B (zh) * 2016-05-12 2018-12-25 沈阳药科大学 一种改善螺内酯体外溶出及流动性的药物组合物
JP6918392B2 (ja) * 2021-01-13 2021-08-11 築野食品工業株式会社 粉末製造における歩留向上又は粉末使用における微粉末の発生、飛散若しくは固化抑制剤

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU84875A1 (fr) * 1983-06-27 1985-03-29 Oreal Compositions tinctoriales pour fibres keratiniques a base de colorants directs et de gomme de xanthane
DE3720757A1 (de) * 1987-06-24 1989-01-05 Bayer Ag Dhp-manteltablette
CH675537A5 (ko) * 1988-03-25 1990-10-15 Ciba Geigy Ag
JP3037393B2 (ja) * 1990-10-22 2000-04-24 大正薬品工業株式会社 経口投与用固形薬剤の製造方法
WO1992009275A1 (en) * 1990-11-30 1992-06-11 Yamanouchi Pharmaceutical Co., Ltd. Quick release coated preparation
US5656290A (en) * 1993-02-26 1997-08-12 The Procter & Gamble Company Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
US5651983A (en) * 1993-02-26 1997-07-29 The Procter & Gamble Company Bisacodyl dosage form for colonic delivery
JP3247511B2 (ja) * 1993-09-07 2002-01-15 山之内製薬株式会社 医薬用組成物
JP3096666B2 (ja) * 1996-11-01 2000-10-10 藤崎電機株式会社 粉体を造粒する方法及びその装置
JP3870470B2 (ja) * 1997-02-07 2007-01-17 大正製薬株式会社 マルチプルユニットタイプ徐放性錠剤
DE19709663A1 (de) * 1997-03-10 1998-09-17 Basf Ag Verwendung von redispergierbaren Polymerpulvern oder Polymergranulaten als Bindemittel zur Herstellung von festen pharmazeutischen Darreichungsformen
JP4063386B2 (ja) * 1998-01-29 2008-03-19 キッセイ薬品工業株式会社 速放性経口医薬品組成物
JP4438121B2 (ja) * 1998-04-27 2010-03-24 大正製薬株式会社 口腔内速崩錠及びその製造方法
GB9816899D0 (en) * 1998-08-05 1998-09-30 Boots Co Plc Therapeutic agents
EP1203580A4 (en) * 1999-06-18 2004-06-30 Takeda Chemical Industries Ltd SOLID PREPARATIONS WITH FAST DISINTEGRATION

Also Published As

Publication number Publication date
JP2005082503A (ja) 2005-03-31
TWI344376B (en) 2011-07-01
TW200514571A (en) 2005-05-01
CN100389750C (zh) 2008-05-28
WO2005023222A1 (ja) 2005-03-17
KR20060119860A (ko) 2006-11-24
CN1842324A (zh) 2006-10-04
JP4575654B2 (ja) 2010-11-04

Similar Documents

Publication Publication Date Title
AP2089A (en) Compositions and methods for combination antiviraltherapy
HK1080717A1 (en) Pharmaceutical compositions with improved dissolution
EP1654005A4 (en) STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR PREPARATION
GB0411940D0 (en) Methods and compositions
IL173639A (en) Ppar-activating compound and pharmaceutical composition containing same
EP1701725A4 (en) PROCESS AND COMPOSITIONS
IL197889A (en) Pyridylvinylazacyclopentane compound and pharmaceutical compositions comprising same
HU0301154D0 (en) Pharmaceutical composition
IL183986A0 (en) Pharmaceutical compounds and compositions
IL182126A (en) Preparations containing and used in the history of 5-phenoxyalkoxypsoralen
GB0300427D0 (en) Pharmaceutical composition
HK1092711A1 (en) Pharmeceutical composition with improved solubility and fluidity
GB0307866D0 (en) Pharmaceutical composition
EP1699458A4 (en) PHARMACEUTICAL COMPOSITION
GB0329232D0 (en) Pharmaceutical composition
GB0317663D0 (en) Pharmaceutical composition
HK1093896A1 (en) Medicinal composition
AU2003267231A8 (en) Pharmaceutical compositions with improved dissolution
EP1600445A4 (en) CURATIVE PREPARATION
GB0300885D0 (en) Pharmaceutical composition
EP1655029A4 (en) MEDICINAL COMPOSITIONS
HK1095737A1 (en) Medicinal composition in solution form
GB0306933D0 (en) Pharmaceutical composition
GB0307869D0 (en) Pharmaceutical composition
GB0307862D0 (en) Pharmaceutical composition

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130903