HK1088301A1 - S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine maleate hydrochloride crystalline salt ; - Google Patents

S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine maleate hydrochloride crystalline salt ;

Info

Publication number
HK1088301A1
HK1088301A1 HK06108667.9A HK06108667A HK1088301A1 HK 1088301 A1 HK1088301 A1 HK 1088301A1 HK 06108667 A HK06108667 A HK 06108667A HK 1088301 A1 HK1088301 A1 HK 1088301A1
Authority
HK
Hong Kong
Prior art keywords
iminoethyl
ethyl
amino
methyl
crystalline salt
Prior art date
Application number
HK06108667.9A
Other languages
English (en)
Inventor
Ahmad Sheikh
Lyle R Brostrom
Ann M Czyzewski
Vahid Zia
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of HK1088301A1 publication Critical patent/HK1088301A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
HK06108667.9A 2003-03-11 2006-08-04 S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine maleate hydrochloride crystalline salt ; HK1088301A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45349603P 2003-03-11 2003-03-11
PCT/IB2004/000678 WO2004080956A1 (en) 2003-03-11 2004-03-04 S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine maleate hydrochloride crystalline salt

Publications (1)

Publication Number Publication Date
HK1088301A1 true HK1088301A1 (en) 2006-11-03

Family

ID=32990778

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06108667.9A HK1088301A1 (en) 2003-03-11 2006-08-04 S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine maleate hydrochloride crystalline salt ;

Country Status (33)

Country Link
US (2) US20050038120A1 (pt)
EP (1) EP1603872B1 (pt)
JP (1) JP4794433B2 (pt)
KR (2) KR100927911B1 (pt)
CN (1) CN100460387C (pt)
AR (1) AR043521A1 (pt)
AT (1) ATE509909T1 (pt)
AU (1) AU2004220266B2 (pt)
BR (1) BRPI0408226A (pt)
CA (1) CA2518745C (pt)
CL (1) CL2004000472A1 (pt)
CO (1) CO5611122A2 (pt)
CY (1) CY1112461T1 (pt)
DK (1) DK1603872T3 (pt)
ES (1) ES2363001T3 (pt)
GT (1) GT200400040A (pt)
HK (1) HK1088301A1 (pt)
IL (1) IL170554A (pt)
MX (1) MXPA05008674A (pt)
NL (1) NL1025691C2 (pt)
NO (1) NO20054645L (pt)
NZ (1) NZ574218A (pt)
PA (1) PA8597701A1 (pt)
PE (1) PE20050309A1 (pt)
PL (1) PL1603872T3 (pt)
PT (1) PT1603872E (pt)
RU (1) RU2357953C2 (pt)
SG (1) SG155782A1 (pt)
SI (1) SI1603872T1 (pt)
TW (1) TWI352076B (pt)
UY (1) UY28229A1 (pt)
WO (1) WO2004080956A1 (pt)
ZA (1) ZA200506459B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6094101A (en) * 1999-03-17 2000-07-25 Tropian, Inc. Direct digital frequency synthesis enabling spur elimination
PL1793187T3 (pl) * 2004-09-21 2012-07-31 G & I Irtech S L Sposób i urządzenie do spiekania i/lub suszenia sproszkowanych materiałów z użyciem promieniowania podczerwonego

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI0765308T1 (en) * 1994-06-15 2000-08-31 The Wellcome Foundation Limited Enzyme inhibitors
ATE313525T1 (de) * 2000-03-24 2006-01-15 Pharmacia Corp Amidino-verbindungen als hemmstoffe der stickstoffmonoxid-synthase
AR031609A1 (es) * 2000-09-15 2003-09-24 Pharmacia Corp Derivados de acido 2-amino-2-alquil-3 heptenoico y heptinoico utiles como inhibidores de oxido nitrico sintetasa
AR031608A1 (es) * 2000-09-15 2003-09-24 Pharmacia Corp Derivados de los acidos 2-amino-2-alquil-3-hexenoico y -hexinoico utiles como inhibidores de oxido nitrico sintetasa

Also Published As

Publication number Publication date
MXPA05008674A (es) 2005-10-18
NL1025691A1 (nl) 2004-09-14
IL170554A (en) 2011-10-31
CA2518745C (en) 2010-10-19
RU2357953C2 (ru) 2009-06-10
JP2006519838A (ja) 2006-08-31
NO20054645D0 (no) 2005-10-10
CY1112461T1 (el) 2015-12-09
NL1025691C2 (nl) 2006-06-30
KR20090048521A (ko) 2009-05-13
UY28229A1 (es) 2004-11-08
EP1603872B1 (en) 2011-05-18
BRPI0408226A (pt) 2006-03-01
SI1603872T1 (sl) 2011-07-29
ZA200506459B (en) 2006-11-29
KR20050107617A (ko) 2005-11-14
AR043521A1 (es) 2005-08-03
DK1603872T3 (da) 2011-07-18
CL2004000472A1 (es) 2005-05-13
TW200508185A (en) 2005-03-01
PL1603872T3 (pl) 2011-09-30
PE20050309A1 (es) 2005-05-04
US7767850B2 (en) 2010-08-03
EP1603872A1 (en) 2005-12-14
NZ574218A (en) 2009-11-27
SG155782A1 (en) 2009-10-29
PT1603872E (pt) 2011-06-07
PA8597701A1 (es) 2005-02-04
WO2004080956A1 (en) 2004-09-23
GT200400040A (es) 2005-01-14
NO20054645L (no) 2005-11-25
JP4794433B2 (ja) 2011-10-19
ES2363001T3 (es) 2011-07-18
CO5611122A2 (es) 2006-02-28
AU2004220266A1 (en) 2004-09-23
CA2518745A1 (en) 2004-09-23
CN1787993A (zh) 2006-06-14
KR100927911B1 (ko) 2009-11-19
TWI352076B (en) 2011-11-11
ATE509909T1 (de) 2011-06-15
AU2004220266B2 (en) 2010-08-19
US20050038120A1 (en) 2005-02-17
US20090215891A1 (en) 2009-08-27
CN100460387C (zh) 2009-02-11
RU2005125833A (ru) 2006-05-10

Similar Documents

Publication Publication Date Title
PL360967A1 (en) Pharmaceutical compound containing donepezyl hydrochloride
GEP20094625B (en) Amidino compound and salts thereof useful as nitric oxide synthase inhibitors
IL164155A (en) Method for the preparation of crystalline quetiapine hemifumarate form i
HK1052502A1 (en) Hydrochloride salts of 5-Ä4-Ä2-(N-methyl-n-2-pyridyl) amino) ethoxyÜbenzylÜthiazolidine-2,4-dione
PL379385A1 (pl) Nowe związki 2-pirydynyloetylobenzamidowe
IL170037A (en) Synthesis of quetiapine and quetiapine hemifumarate salt
HK1171030A1 (en) Hydrochloride salts of a glycopeptide phosphonate derivative
ZA200501418B (en) Benzenesulfonate salts of 4-fluoro-2-cyanopyrrolidine derivatives
AU2003214112A1 (en) Salts of nateglinide
HUP0401694A3 (en) Crystal forms of a hydrochloride salt of a hydroxynorephedrine derivative, pharmaceutical compositions comprising thereof and use
AU2003269747A1 (en) A stable aqueous composition of a peptide
PL372880A1 (en) Crystalline parecoxib sodium
HK1088301A1 (en) S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine maleate hydrochloride crystalline salt ;
PT1499587E (pt) Processo para síntese de sais de dissulfureto farmaceuticamente activos
GB0211626D0 (en) Succinnylated fish gelatin for use as a blood plasma expander
HK1061857A1 (en) A novel crystalline form of 6-hydroxy-3-(4-Ä2-(piperidin-1-yl)ethoxyÜphenoxy)-2-(4-methoxyphenyl)benzoÄBÜthiophene hydrochloride
TW200503680A (en) S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine maleate form ii crystalline salt
TW200504000A (en) Methods for selectively removing counterions from compounds and compounds derived from such methods
MXPA05009779A (es) Sal cristalina de salicilato de s-[2-[(1-iminoetil)amino]etil]-2-metil-l-cisteina monohidrato.
MXPA05009302A (es) Sal cristalina de maleato de s-[2-[(1-iminoetil)amino]etil]-2-metil-l-cisteina.
ITBO20040045A1 (it) Procedimento per l'applicazione di un inserto in una cinghia dentata
GB0206708D0 (en) Pharmaceutical salts
GB0204683D0 (en) Pharmaceutical salts
AU2003243605A8 (en) 3-'2-(dimethylamino) ethyl
TW538975U (en) Improved structure of tool for plating of film

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180304