PT1499587E - Processo para síntese de sais de dissulfureto farmaceuticamente activos - Google Patents
Processo para síntese de sais de dissulfureto farmaceuticamente activos Download PDFInfo
- Publication number
- PT1499587E PT1499587E PT37243011T PT03724301T PT1499587E PT 1499587 E PT1499587 E PT 1499587E PT 37243011 T PT37243011 T PT 37243011T PT 03724301 T PT03724301 T PT 03724301T PT 1499587 E PT1499587 E PT 1499587E
- Authority
- PT
- Portugal
- Prior art keywords
- pharmaceutically active
- active disulfide
- disulfide salts
- synthesizing
- synthesizing pharmaceutically
- Prior art date
Links
- 150000002019 disulfides Chemical class 0.000 title 1
- 230000002194 synthesizing effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/22—Esters of monothiocarboxylic acids having carbon atoms of esterified thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
- C07C319/24—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides by reactions involving the formation of sulfur-to-sulfur bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/135,756 US6504049B1 (en) | 2002-04-30 | 2002-04-30 | Process for synthesizing pharmaceutically active disulfide salts |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1499587E true PT1499587E (pt) | 2014-11-21 |
Family
ID=22469512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT37243011T PT1499587E (pt) | 2002-04-30 | 2003-04-29 | Processo para síntese de sais de dissulfureto farmaceuticamente activos |
Country Status (10)
Country | Link |
---|---|
US (1) | US6504049B1 (pt) |
EP (1) | EP1499587B1 (pt) |
JP (1) | JP4478561B2 (pt) |
AU (1) | AU2003231169B2 (pt) |
CA (1) | CA2483775C (pt) |
DK (1) | DK1499587T3 (pt) |
ES (1) | ES2523653T3 (pt) |
MX (1) | MXPA04010859A (pt) |
PT (1) | PT1499587E (pt) |
WO (1) | WO2003093226A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2811987A1 (fr) * | 2000-07-18 | 2002-01-25 | Expansia Sa | Procede de preparation du 2,2'-dithiobis(ethanesulfonate) de disodium |
US8710095B2 (en) | 2002-04-30 | 2014-04-29 | Bionumerik Pharmaceuticals, Inc. | Drugs for prophylaxis or mitigation of taxane-induced neurotoxicity |
US7317124B2 (en) | 2003-11-13 | 2008-01-08 | Sanofi-Aventis Deutschland Gmbh | Ortho-substituted pentafluorosulfanylbenzenes, process for their preparation and their use as valuable synthetic intermediates |
WO2005058005A2 (en) * | 2003-12-17 | 2005-06-30 | Bionumerik Pharmaceuticals, Inc. | Process for synthesizing disulfides |
US7282602B2 (en) * | 2004-09-21 | 2007-10-16 | Bionumerik Pharmaceuticals, Inc. | Medicinal disulfide salts |
CA2647297A1 (en) * | 2006-03-16 | 2007-09-27 | Bionumerik Pharmaceuticals, Inc. | Anti-cancer activity augmentation compounds and formulations and methods of use thereof |
JP5109081B2 (ja) * | 2006-04-26 | 2012-12-26 | 東洋紡株式会社 | アルケンスルホン酸塩を用いたチオカルボアルキルアルカンスルホン酸塩、メルカプトアルカンスルホン酸塩およびジチオビス(アルカンスルホン酸)塩の製造方法 |
CA2706378C (en) * | 2007-11-20 | 2017-09-12 | Lankenau Institute For Medical Research | Disulfide chemotherapeutic agents and methods of use thereof |
CA2718233A1 (en) | 2008-03-14 | 2009-09-17 | Bionumerik Pharmaceuticals, Inc. | Compositions and methods of use of compounds to increase cancer patient survival time |
DK2249825T3 (en) | 2008-03-14 | 2016-01-11 | Bionumerik Pharmaceuticals Inc | Treatment methods and compositions for lung cancer, adenocarcinoma, and other medical conditions |
EP2430178B1 (en) | 2009-05-15 | 2014-07-09 | Lankenau Institute for Medical Research | Methods and kits for measuring toxicity and oxidative stress in live cells |
CN108914171B (zh) * | 2018-07-19 | 2020-05-19 | 广东工业大学 | 一种加速铜沉积添加剂及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2396879A (en) * | 1945-04-12 | 1946-03-19 | Eastman Kodak Co | Sulphur-containing esters |
CS252564B1 (cs) * | 1985-06-17 | 1987-09-17 | Jiri Jary | Způsob výroby 2-merkaptoethansulfonové kyseliny |
EP0934261B1 (en) * | 1996-10-01 | 2001-10-31 | Bionumerik Pharmaceuticals, Inc. | Process for producing dithiobis-alkanesulfonates and phosphonates |
FR2811987A1 (fr) | 2000-07-18 | 2002-01-25 | Expansia Sa | Procede de preparation du 2,2'-dithiobis(ethanesulfonate) de disodium |
-
2002
- 2002-04-30 US US10/135,756 patent/US6504049B1/en not_active Expired - Lifetime
-
2003
- 2003-04-29 EP EP03724301.1A patent/EP1499587B1/en not_active Expired - Lifetime
- 2003-04-29 MX MXPA04010859A patent/MXPA04010859A/es active IP Right Grant
- 2003-04-29 JP JP2004501366A patent/JP4478561B2/ja not_active Expired - Lifetime
- 2003-04-29 PT PT37243011T patent/PT1499587E/pt unknown
- 2003-04-29 AU AU2003231169A patent/AU2003231169B2/en not_active Ceased
- 2003-04-29 WO PCT/US2003/013178 patent/WO2003093226A1/en active Application Filing
- 2003-04-29 CA CA2483775A patent/CA2483775C/en not_active Expired - Fee Related
- 2003-04-29 ES ES03724301.1T patent/ES2523653T3/es not_active Expired - Lifetime
- 2003-04-29 DK DK03724301.1T patent/DK1499587T3/en active
Also Published As
Publication number | Publication date |
---|---|
JP4478561B2 (ja) | 2010-06-09 |
AU2003231169A1 (en) | 2003-11-17 |
ES2523653T3 (es) | 2014-11-28 |
CA2483775C (en) | 2011-02-08 |
AU2003231169B2 (en) | 2008-09-04 |
US6504049B1 (en) | 2003-01-07 |
DK1499587T3 (en) | 2015-01-26 |
CA2483775A1 (en) | 2003-11-13 |
EP1499587A1 (en) | 2005-01-26 |
WO2003093226A1 (en) | 2003-11-13 |
JP2005523935A (ja) | 2005-08-11 |
EP1499587B1 (en) | 2014-11-05 |
MXPA04010859A (es) | 2005-02-14 |
EP1499587A4 (en) | 2006-05-24 |
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