AR031609A1 - Derivados de acido 2-amino-2-alquil-3 heptenoico y heptinoico utiles como inhibidores de oxido nitrico sintetasa - Google Patents

Derivados de acido 2-amino-2-alquil-3 heptenoico y heptinoico utiles como inhibidores de oxido nitrico sintetasa

Info

Publication number
AR031609A1
AR031609A1 ARP010104368A ARP010104368A AR031609A1 AR 031609 A1 AR031609 A1 AR 031609A1 AR P010104368 A ARP010104368 A AR P010104368A AR P010104368 A ARP010104368 A AR P010104368A AR 031609 A1 AR031609 A1 AR 031609A1
Authority
AR
Argentina
Prior art keywords
amino
inhibitors
nitrico
heptinoico
heptenoico
Prior art date
Application number
ARP010104368A
Other languages
English (en)
Inventor
Ronald Keith Webber
Alok K Awasthi
Mahima Trivedi
James A Sikorski
Donald W Hansen Jr
Barnett S Pitzele
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of AR031609A1 publication Critical patent/AR031609A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/30—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same unsaturated acyclic carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
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    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
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    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
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  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
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Abstract

Se relaciona con ácido 2-amino-2-alquil-3-heptenoico y heptinoico y su uso terapéutico, en particular su uso como inhibidotes de oxido nítrico sintetasa.
ARP010104368A 2000-09-15 2001-09-14 Derivados de acido 2-amino-2-alquil-3 heptenoico y heptinoico utiles como inhibidores de oxido nitrico sintetasa AR031609A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23268400P 2000-09-15 2000-09-15

Publications (1)

Publication Number Publication Date
AR031609A1 true AR031609A1 (es) 2003-09-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010104368A AR031609A1 (es) 2000-09-15 2001-09-14 Derivados de acido 2-amino-2-alquil-3 heptenoico y heptinoico utiles como inhibidores de oxido nitrico sintetasa

Country Status (9)

Country Link
US (1) US20020072630A1 (es)
EP (1) EP1317417A2 (es)
JP (1) JP2004509096A (es)
AR (1) AR031609A1 (es)
AU (1) AU2001289076A1 (es)
CA (1) CA2421279A1 (es)
MX (1) MXPA03002272A (es)
NZ (1) NZ524560A (es)
WO (1) WO2002022558A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003097163A2 (en) * 2002-05-16 2003-11-27 Pharmacia Corporation Using a selective inos inhibitor for the treatment of respiratory diseases and conditions
KR100927911B1 (ko) * 2003-03-11 2009-11-19 파마시아 코포레이션 에스-[2-[(1-이미노에틸)아미노]에틸]-2-메틸-엘-시스테인 말레에이트 히드로클로라이드 결정질 염

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0751930T3 (da) * 1994-03-24 2000-04-17 Searle & Co Amidinoderivater anvendelige som nitrogenoxid-synthase-inhibitorer
HUP0101467A3 (en) * 1998-03-11 2003-03-28 G D Searle & Co Skokie Halogenated amidino amino acid derivatives useful as nitric monoxide synthase inhibitors

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NZ524560A (en) 2004-12-24
WO2002022558A3 (en) 2002-07-18
AU2001289076A1 (en) 2002-03-26
EP1317417A2 (en) 2003-06-11
US20020072630A1 (en) 2002-06-13
WO2002022558A2 (en) 2002-03-21
JP2004509096A (ja) 2004-03-25
MXPA03002272A (es) 2003-06-06
CA2421279A1 (en) 2002-03-21

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