HK1087409A1 - Novel heteroaryl derivative - Google Patents

Novel heteroaryl derivative

Info

Publication number
HK1087409A1
HK1087409A1 HK06109338.6A HK06109338A HK1087409A1 HK 1087409 A1 HK1087409 A1 HK 1087409A1 HK 06109338 A HK06109338 A HK 06109338A HK 1087409 A1 HK1087409 A1 HK 1087409A1
Authority
HK
Hong Kong
Prior art keywords
optionally substituted
heteroaryl derivative
heteroaryl
novel heteroaryl
single bond
Prior art date
Application number
HK06109338.6A
Other languages
English (en)
Inventor
Ken-Ichi Watanabe
Katsunori Maruta
Kantaro Ushiroda
Ryu Nagata
Original Assignee
Dainippon Sumitomo Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Sumitomo Pharma Co filed Critical Dainippon Sumitomo Pharma Co
Publication of HK1087409A1 publication Critical patent/HK1087409A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333Radicals substituted by oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12Radicals substituted by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrrole Compounds (AREA)
HK06109338.6A 2003-07-15 2006-08-22 Novel heteroaryl derivative HK1087409A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003274684 2003-07-15
PCT/JP2004/010282 WO2005012245A1 (fr) 2003-07-15 2004-07-13 Nouveau dérivé d'hétéroaryle

Publications (1)

Publication Number Publication Date
HK1087409A1 true HK1087409A1 (en) 2006-10-13

Family

ID=34113749

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06109338.6A HK1087409A1 (en) 2003-07-15 2006-08-22 Novel heteroaryl derivative

Country Status (12)

Country Link
US (2) US7425642B2 (fr)
EP (1) EP1647546B1 (fr)
JP (2) JP4820169B2 (fr)
KR (1) KR101086654B1 (fr)
CN (1) CN100516041C (fr)
AT (1) ATE556051T1 (fr)
CA (1) CA2531064C (fr)
ES (1) ES2383895T3 (fr)
HK (1) HK1087409A1 (fr)
MX (1) MXPA06000539A (fr)
TW (1) TW200523249A (fr)
WO (1) WO2005012245A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1837329A4 (fr) * 2005-01-14 2009-08-05 Dainippon Sumitomo Pharma Co Nouveau derive d'heteroaryle
US20060241073A1 (en) * 2005-04-20 2006-10-26 Wanders Ronaldus J A Means and methods for counteracting fatty acid accumulation
US8273738B2 (en) 2006-09-05 2012-09-25 Kyowa Hakko Kirin Co., Ltd. Imidazole derivatives
US20090054450A1 (en) * 2007-06-19 2009-02-26 Ironwood Pharmaceuticals, Inc. Compositions and methods of use for treating or preventing lipid related disorders
WO2010050422A1 (fr) 2008-10-31 2010-05-06 大日本住友製薬株式会社 Agent destiné au traitement du diabète
MX2011010030A (es) * 2009-03-26 2011-10-11 Dainippon Sumitomo Pharma Co Medicamento novedoso para el tratamiento del deterioro cognitivo.
JPWO2011002012A1 (ja) * 2009-07-01 2012-12-13 キッセイ薬品工業株式会社 Sglt1阻害薬とインスリン抵抗性改善薬を組み合わせてなる医薬
AU2011210765A1 (en) 2010-01-28 2012-09-13 President And Fellows Of Harvard College Compositions and methods for enhancing proteasome activity
WO2012007500A2 (fr) 2010-07-15 2012-01-19 Bayer Cropscience Ag Nouveaux composés hétérocycliques servant d'agents de lutte contre les nuisibles
SI2707101T1 (sl) 2011-05-12 2019-06-28 Proteostasis Therapeutics, Inc. Regulatorji proteostaze
US10266490B2 (en) * 2012-03-16 2019-04-23 Georgetown University Radioprotector compounds
WO2014116228A1 (fr) 2013-01-25 2014-07-31 President And Fellows Of Harvard College Inhibiteurs de l'usp14 utilisables en vue du traitement ou de la prévention d'infections virales
WO2015073528A1 (fr) 2013-11-12 2015-05-21 Proteostasis Therapeutics, Inc. Composés renforçant l'activité des protéasomes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2752361A1 (de) * 1977-11-24 1979-06-07 Troponwerke Gmbh & Co Kg Neue indolderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JP2001514631A (ja) 1997-03-07 2001-09-11 ノボ ノルディスク アクティーゼルスカブ 4,5,6,7−テトラヒドロ−チエノ[3,2−c]ピリジン誘導体類、それらの製造方法及び使用
US6177443B1 (en) * 1997-03-07 2001-01-23 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno[3, 2-C]pyridine derivatives, their preparation and use
JP2002121186A (ja) 2000-05-22 2002-04-23 Takeda Chem Ind Ltd チロシンホスファターゼ阻害剤
US6911468B2 (en) * 2000-05-22 2005-06-28 Takeda Chemical Industries, Ltd. Tyrosine phosphatase inhibitors
SI1294724T1 (sl) * 2000-06-26 2006-08-31 Pfizer Prod Inc Pirolo(2,3-d)primidinske spojine kot imunosupresivna sredstva
ATE401306T1 (de) * 2001-04-19 2008-08-15 Dainippon Sumitomo Pharma Co Pyrrolderivat
JP2003171275A (ja) 2001-12-11 2003-06-17 Sumitomo Pharmaceut Co Ltd PPARδアゴニスト
WO2004048341A1 (fr) * 2002-11-28 2004-06-10 Sumitomo Pharmaceuticals Co., Ltd. Nouveau derive heteroaryle

Also Published As

Publication number Publication date
US20060194857A1 (en) 2006-08-31
TWI331142B (fr) 2010-10-01
EP1647546B1 (fr) 2012-05-02
KR101086654B1 (ko) 2011-11-24
ATE556051T1 (de) 2012-05-15
JP2011251974A (ja) 2011-12-15
MXPA06000539A (es) 2006-03-30
ES2383895T3 (es) 2012-06-27
CA2531064A1 (fr) 2005-02-10
EP1647546A1 (fr) 2006-04-19
TW200523249A (en) 2005-07-16
US20080306275A1 (en) 2008-12-11
US7425642B2 (en) 2008-09-16
JP4820169B2 (ja) 2011-11-24
JPWO2005012245A1 (ja) 2006-09-14
EP1647546A4 (fr) 2008-07-23
CN100516041C (zh) 2009-07-22
WO2005012245A1 (fr) 2005-02-10
CA2531064C (fr) 2012-05-22
KR20060040681A (ko) 2006-05-10
CN1849303A (zh) 2006-10-18

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160713